{"id":4996,"date":"2024-06-04T15:38:35","date_gmt":"2024-06-04T06:38:35","guid":{"rendered":"https:\/\/smartskin-clinic.com\/?page_id=4996"},"modified":"2026-09-06T15:10:42","modified_gmt":"2026-09-06T06:10:42","slug":"facial-wrinkles","status":"publish","type":"page","link":"https:\/\/smartskin-clinic.com\/en\/facial-wrinkles\/","title":{"rendered":"For those who suffer from wrinkles on the face and neck. Next generation hyaluronic acid treatment selected by 100 cosmetic doctors for its high praise \uff5cTo regain a youthful impression..."},"content":{"rendered":"<div class=\"swell-block-fullWide pc-py-0 sp-py-0 alignfull\" style=\"background-color:#f7f7f7\"><div class=\"swell-block-fullWide__inner\">\n<h2 class=\"wp-block-heading is-style-section_ttl\"><\/h2>\n<\/div><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"819\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9-819x1024.jpg\" alt=\"\" class=\"wp-image-5160\" style=\"width:471px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9-819x1024.jpg 819w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9-240x300.jpg 240w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9-768x960.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9-10x12.jpg 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/\u5c0f\u898b\u51fa\u3057\u3092\u8ffd\u52a0-666e7461d86e9.jpg 1000w\" sizes=\"auto, (max-width: 819px) 100vw, 819px\" \/><\/figure>\n<\/div>\n\n\n<!-- ======================================\n     \u76e3\u4fee\u8005\u60c5\u5831 \u2013 Smart Skin Clinic\n     Brand Colors: #ffffff #000000 #f5f5f5 #a3e3fc\n====================================== -->\n<section class=\"ssc-supervisor\">\n\n  <!-- \u76e3\u4fee\u8005\u60c5\u5831\u30bf\u30a4\u30c8\u30eb -->\n  <div class=\"ssc-supervisor-title-wrapper\">\n    <span class=\"ssc-supervisor-title\">Supervisor Information<\/span>\n  <\/div>\n\n  <div class=\"ssc-supervisor-inner\">\n\n    <!-- \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f -->\n    <div class=\"ssc-supervisor-photo\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg\" alt=\"Kota Ishii, Chief Medical Director, Smart Skin Clinic Group\" loading=\"lazy\" \/>\n    <\/div>\n\n    <!-- \u30c6\u30ad\u30b9\u30c8\u60c5\u5831 -->\n    <div class=\"ssc-supervisor-text\">\n\n      <p class=\"ssc-supervisor-role\">Group Chief Director, Smart Skin Clinic Group<\/p>\n      <p class=\"ssc-supervisor-name translation-block\"><ruby>Ishii<rt>Ishii<\/rt><\/ruby> <ruby>Kota<rt>Kota<\/rt><\/ruby><\/p>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Career<\/h4>\n        <p>Graduated from Juntendo University School of Medicine<\/p>\n        <p>Worked at Tokyo Women's Medical University Hospital and affiliated facilities<\/p>\n        <p>Worked at a major aesthetic clinic in Tokyo<\/p>\n      <\/div>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Affiliations \/ Qualifications<\/h4>\n        <p>Board-certified specialist, Japan Surgical Society<\/p>\n        <p>Board-certified specialist, Japanese Society of Anti-Aging Medicine<\/p>\n      <\/div>\n\n    <\/div><!-- \/.text -->\n  <\/div><!-- \/.inner -->\n<\/section>\n\n<style>\n\/* =========================================================\n  Smart Skin Clinic \u2013 Supervisor Component (Monotone + Water)\n========================================================= *\/\n\n\/* \u25c7 \u30d1\u30ec\u30c3\u30c8 *\/\n:root{\n  --ssc-black:#000000;\n  --ssc-white:#ffffff;\n  --ssc-gray:#f5f5f5;\n  --ssc-water:#a3e3fc;   \/* \u30a2\u30af\u30bb\u30f3\u30c8\u6c34\u8272 *\/\n}\n\n\/* \u30bb\u30af\u30b7\u30e7\u30f3 *\/\n.ssc-supervisor{\n  background:var(--ssc-gray);\n  padding:40px 5%;\n  border:1px solid #e0e0e0;\n  border-radius:8px;\n  margin:40px 0;\n  color:var(--ssc-black);\n  font-family:\"Noto Sans JP\",\"Hiragino Sans\",\"Helvetica Neue\",Arial,sans-serif;\n}\n\n\/* \u30bf\u30a4\u30c8\u30eb *\/\n.ssc-supervisor-title-wrapper {\n  font-size: 1.5rem;\n  font-weight: 700;\n  margin: 0 0 24px;\n  display: flex;\n  align-items: flex-end;\n  gap: 8px;\n  color: var(--ssc-black);\n}\n\n.ssc-supervisor-title {\n  font-size: 1.5rem;\n  font-weight: 700;\n  color: var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30ec\u30a4\u30a2\u30a6\u30c8 *\/\n.ssc-supervisor-inner{\n  display:flex;\n  gap:28px;\n  flex-wrap:wrap;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8 *\/\n.ssc-supervisor-text{\n  flex:1 1 260px;\n  min-width:260px;\n}\n.ssc-supervisor-role{\n  font-size:0.9rem;\n  color:var(--ssc-black);  \/* \u9ed2\u6587\u5b57\u306b\u4fee\u6b63 *\/\n  margin:0 0 4px;\n}\n.ssc-supervisor-name{\n  font-size:1.25rem;\n  font-weight:700;\n  margin:0 0 16px;\n  background-color:transparent;  \/* \u80cc\u666f\u306e\u8272\u3092\u900f\u660e\u306b\u8a2d\u5b9a *\/\n  color:var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30d6\u30ed\u30c3\u30af *\/\n.ssc-supervisor-block{\n  margin-bottom:18px;\n}\n.ssc-supervisor-block h4{\n  font-size:1rem;\n  font-weight:600;\n  margin:0 0 6px;\n  color:var(--ssc-black);\n  border-left:4px solid var(--ssc-water);\n  padding-left:8px;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8\u8868\u793a\u306e\u5909\u66f4\uff08\u7b87\u6761\u66f8\u304d\u306f\u4f7f\u7528\u305b\u305a\u3001\u30b7\u30f3\u30d7\u30eb\u306b\u8868\u793a\uff09 *\/\n.ssc-supervisor-block p{\n  font-size:1rem;\n  margin: 0 0 10px;\n  color: var(--ssc-black);\n  line-height: 1.6;\n}\n\n\/* \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f *\/\n.ssc-supervisor-photo{\n  flex:0 0 190px;\n  max-width:190px;\n}\n.ssc-supervisor-photo img{\n  width:100%;\n  height:auto;\n  display:block;\n  border-radius:8px;\n}\n\n\/* \u30b9\u30de\u30db *\/\n@media(max-width:600px){\n  .ssc-supervisor-inner{\n    flex-direction:column;\n    gap:20px;\n  }\n  .ssc-supervisor-photo{\n    flex:0 0 auto;\n    max-width:150px;\n    margin:0 auto;\n  }\n}\n<\/style>\n\n\n\n<h2 class=\"wp-block-heading\">Introduction: We, too, have struggled with wrinkles<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\"Every time I look in the mirror, I notice the wrinkles on my face and neck\u2026\"<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Do you find yourself thinking this way? Deep wrinkles etched at the corners of the eyes and mouth, and horizontal lines appearing on the neck. As the years go by, wrinkles seem only to increase.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The delicate areas around the eyes, mouth, and neck in particular are prone to wrinkles. Every time you smile, look surprised, or tilt your head, the wrinkles are thrown into sharp relief\u2026 Even if they don't bother you, having someone point them out can shake your confidence in an instant.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But you are not alone.<strong>More people than you might imagine struggle with wrinkles on the face and neck.<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As we age, it is only natural for collagen and elastin\u2014which maintain the skin's firmness and elasticity\u2014to decrease.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What matters most is a positive mindset\u2014accepting who you are now while striving to move closer to your ideal self. Wrinkles are proof of a life well lived. In fact, you can even choose to see them as attractive.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That said, you probably still want to keep a youthful look&#8230; There is a treatment that can meet exactly that wish.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Today, we would like to introduce \"Profhilo injections,\" a treatment generating a great deal of buzz among cosmetic doctors.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\"Profhilo injections\" are attracting attention as a next-generation hyaluronic acid injection. A major feature is that they can address wrinkles not only on the face but also on the neck. They help restore firmness and elasticity from within the skin, so you can achieve a natural, youthful appearance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Next-generation hyaluronic acid: What is Profhilo?<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/10\/\u30d7\u30ed\u30d5\u30a1\u30a4\u30ed\u5546\u54c1\u753b\u50cf.png\" alt=\"Profhilo Product Images\" class=\"wp-image-1798\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/10\/\u30d7\u30ed\u30d5\u30a1\u30a4\u30ed\u5546\u54c1\u753b\u50cf.png 600w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/10\/\u30d7\u30ed\u30d5\u30a1\u30a4\u30ed\u5546\u54c1\u753b\u50cf-300x250.png 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">What is a Profhilo injection?<strong>\"An injectable moisturizer\" and \"next-generation hyaluronic acid\"<\/strong>These are the names given to this injectable treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Its official product name is \"Profhilo\u00ae.\" On the market since 2015, it is a hyaluronic acid produced using NAHYCO\u2122, a patented technology developed by the Italian company IBSA.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span class=\"swl-marker mark_yellow\"><span class=\"swl-fz u-fz-l\">Because it is a cutting-edge treatment that can address wrinkles and improve skin quality at the same time, it is drawing attention within the cosmetic medicine field<\/span><\/span><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Also,<strong>Unlike ordinary hyaluronic acid, Profhilo injections do not remain in the skin as a solid mass\u2014<\/strong>which is a major advantage.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Using too much ordinary hyaluronic acid carries the risk of an unnatural-looking face, as shown in the post below, but with Profhilo, the next-generation hyaluronic acid, there is no such risk.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1080\" height=\"760\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1-1024x721.png\" alt=\"\" class=\"wp-image-5145\" style=\"width:719px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1-1024x721.png 1024w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1-300x211.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1-768x540.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1-18x12.png 18w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/1.png 1080w\" sizes=\"auto, (max-width: 1080px) 100vw, 1080px\" \/><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-1024x1024.png\" alt=\"\" class=\"wp-image-5146\" style=\"width:712px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-1024x1024.png 1024w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-300x300.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-150x150.png 150w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-768x768.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2-12x12.png 12w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/2.png 1080w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">Profhilo injections are effective for concerns like these<\/h2>\n\n\n\n<div class=\"wp-block-group is-style-kakko_box\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list is-style-check_list\">\n<li><strong><span class=\"swl-marker mark_yellow\"><span class=\"swl-fz u-fz-l\">I want to improve wrinkles and sagging across the entire face (under the eyes, outer corners of the eyes, cheeks, and neck) all at once, while also improving my skin quality<\/span><\/span><\/strong><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">As mentioned earlier, unlike ordinary hyaluronic acid, Profhilo injections do not remain in the skin as a solid mass.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a result, as shown in the case photos below,<strong>an exceptionally natural rejuvenation can be achieved.<\/strong>is what it makes possible.<\/p>\n\n\n\n<div class=\"swell-block-fullWide pc-py-0 sp-py-0 alignfull\" style=\"background-color:#f7f7f7\"><div class=\"swell-block-fullWide__inner l-article\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"444\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-444x1024.jpg\" alt=\"\" class=\"wp-image-5182\" style=\"width:675px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-444x1024.jpg 444w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-130x300.jpg 130w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-768x1772.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-666x1536.jpg 666w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1-5x12.jpg 5w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated1.jpg 780w\" sizes=\"auto, (max-width: 444px) 100vw, 444px\" \/><\/figure>\n<\/div>\n\n\n<div class=\"swell-block-fullWide pc-py-0 sp-py-0 alignfull\" style=\"background-color:#f7f7f7\"><div class=\"swell-block-fullWide__inner l-article\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"444\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-444x1024.jpg\" alt=\"\" class=\"wp-image-5183\" style=\"width:656px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-444x1024.jpg 444w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-130x300.jpg 130w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-768x1772.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-666x1536.jpg 666w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2-5x12.jpg 5w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/06\/LP\u7528_updated2.jpg 780w\" sizes=\"auto, (max-width: 444px) 100vw, 444px\" \/><\/figure>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">If you overdo ordinary hyaluronic acid injections, you run the risk of an unnatural-looking face, as in Ms. Honezawa's post below; a major advantage of Profhilo injections is that they carry no such risk.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"twitter-tweet\" data-width=\"500\" data-dnt=\"true\"><p lang=\"ja\" dir=\"ltr\">aesthetic sense <a href=\"https:\/\/x.com\/hashtag\/%E3%83%92%E3%82%A2%E3%83%AB%E3%83%AD%E3%83%B3%E9%85%B8%E6%B3%A8%E5%85%A5?src=hash&amp;ref_src=twsrc%5Etfw\">#hyaluronic acid injection<\/a> <a href=\"https:\/\/x.com\/hashtag\/%E7%BE%8E%E5%AE%B9%E5%8C%BB%E7%99%82?src=hash&amp;ref_src=twsrc%5Etfw\">#cosmetic medicine<\/a> <a href=\"https:\/\/t.co\/4gdyms95NG\">pic.twitter.com\/4gdyms95NG<\/a><\/p>\u2014 Honezawa \u25ce 39-Year-Old Who Wants to Be Beautiful (@bone_honezawa) <a href=\"https:\/\/x.com\/bone_honezawa\/status\/1797542565820187059?ref_src=twsrc%5Etfw\">June 3, 2024<\/a><\/blockquote><script async src=\"https:\/\/platform.x.com\/widgets.js\" charset=\"utf-8\"><\/script>\n<\/div><\/figure>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_shiny\" id=\"nayami\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a free consultation with a doctor online here<\/span><\/a><\/div>\n\n\n\n<div class=\"swell-block-button is-style-btn_normal\"><a href=\"tel:080-9683-3508\" class=\"swell-block-button__link\"><span>Book a free consultation by phone here<br>080-9683-3508<\/span><\/a><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Effect | Profhilo has a skin-rejuvenating effect<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Profhilo offers the following benefits.<\/p>\n\n\n\n<div style=\"height:12px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-border -border04 wp-block-paragraph\">\u3007 Improvement of wrinkles and sagging<br>\u3007 Improvement of firmness and elasticity (enhanced, dewy skin)<br>\u3007 Lifting effect<br>\u3007 Natural volume enhancement<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"819\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1-819x1024.jpg\" alt=\"Effect\" class=\"wp-image-3638\" style=\"width:500px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1-819x1024.jpg 819w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1-240x300.jpg 240w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1-768x960.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1-10x12.jpg 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/6-1.jpg 1000w\" sizes=\"auto, (max-width: 819px) 100vw, 819px\" \/><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\">When can the effects be felt after treatment?<\/h4>\n\n\n<div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30b9\u30de\u30b9\u30ad\u60a9\u3080\u5973\u6027-150x150.png\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><\/div><div class=\"c-balloon__body -speaking -border-on\"><div class=\"c-balloon__text\">\n<p>When can the effects be felt after treatment?<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div>\n\n<div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-right\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>How soon the effects are felt varies from person to person, but they are often felt gradually from a few days to a few weeks after the injection. The maximum effect is usually felt around one month after the injection.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div>\n\n\n<h4 class=\"wp-block-heading\">How long do the effects last?<\/h4>\n\n\n<div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30b9\u30de\u30b9\u30ad\u60a9\u3080\u5973\u6027-150x150.png\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><\/div><div class=\"c-balloon__body -speaking -border-on\"><div class=\"c-balloon__text\">\n<p>How long do the effects last?<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div>\n\n<div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-right\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>They are said to last from about 6 months to 1 year. For lasting results, we recommend regular injections for maintenance.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div>\n\n\n<h3 class=\"wp-block-heading\">Profhilo's characteristic | Penetrating power that reaches deep and wide in multiple directions<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">So far we have explained the properties of hyaluronic acid. Here, we will explain the characteristics of Profhilo, which also incorporate those properties of hyaluronic acid.<br><br><span class=\"swl-fz u-fz-xl\"><span class=\"swl-marker mark_yellow\">Penetrating power that reaches deep and wide in multiple directions<\/span>\"<\/span><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"819\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1-819x1024.jpg\" alt=\"Spreading Features\" class=\"wp-image-3637\" style=\"width:500px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1-819x1024.jpg 819w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1-240x300.jpg 240w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1-768x960.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1-10x12.jpg 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/5-1.jpg 1000w\" sizes=\"auto, (max-width: 819px) 100vw, 819px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\"><strong>Profhilo at Smart Skin Clinic<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">We use \"Profhilo\u00ae.\"<br><br>As of 2020,<strong><mark>it has been introduced in more than 80 countries<\/mark><\/strong>and is a hyaluronic acid with an extensive track record. More than 500,000 cases have been reported worldwide, and it has also received AMEC &amp; AESTHETICS awards,<strong>a hyaluronic acid whose safety and effectiveness are recognized worldwide<\/strong>.<br><br>Profhilo is the only treatment that can remodel the skin without the use of a device.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">At Smart Skin Clinic, we<span class=\"swl-marker mark_yellow\">A board-certified anti-aging specialist with over 3,000 Profhilo procedures to their credit<\/span>performs the treatment<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">At Smart Skin Clinic,<span class=\"swl-marker mark_yellow\">A board-certified specialist in anti-aging medicine with extensive experience\u2014over 3,000 procedures using Profhilo alone\u2014and a high level of technical expertise<\/span>will always be in charge of the treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This helps ensure not only a high-quality finish but also keeps downtime swelling and pain during the procedure to a minimum.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Below, we share comments we have actually received from our patients.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><span class=\"swl-marker mark_orange\">Since it was on my face, I was worried about injection marks (bruising), but the doctor's technique was excellent and there was zero<\/span>\u2026<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br>I had the injection on my way home from work and took care to wash my face gently when bathing; when I woke up the next day,<span class=\"swl-marker mark_orange\">the marks that had looked like mosquito bites had completely disappeared.<\/span>There was no need for unnecessary face washing before the treatment, and the treatment itself was over quickly in 15-20 minutes. I'm looking forward to my second session on 1\/11.<br><br>The doctor is remarkably quick to understand and is exceptionally skilled at picking up on what you want.<span class=\"swl-marker mark_orange\">Having had many consultations at cosmetic surgery clinics, this is a clinic I would recommend.<\/span>\uff01\uff01\uff01\uff01<br><br><span class=\"swl-marker mark_orange\">The treatment, and the needle work, is very skillful. It does hurt, but the finish is outstanding.<\/span>.<\/p>\n<cite>Excerpt from a Smart Skin Clinic review on Hot Pepper Beauty<\/cite><\/blockquote>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_shiny\" id=\"nayami\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Smart Skin Clinic's commitment to injection treatment<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Following our director's philosophy, we perform injections with the following \"attention to detail.\"<\/p>\n\n\n\n<blockquote class=\"instagram-media\" data-instgrm-captioned data-instgrm-permalink=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\"> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">View this post on Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\">A post shared by Smart Skin Clinic [Aesthetic Dermatology] Jimbocho Juvelook &amp; Profhilo &amp; Sunekos (@smartskin_clinic)<\/a><\/p><\/div><\/blockquote> <script async src=\"\/\/www.instagram.com\/embed.js\"><\/script>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Safety<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Since Profhilo contains absolutely no chemical substances\u2014including cross-linking agents\u2014or biologics, <strong> it can be said to be highly safe <\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Specifically, <strong> this means it is less likely to cause allergic reactions, etc., <\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The reason for this is that Profhilo contains no \"cross-linking agent.\"<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Cross-linking agents may cause allergic reactions, immune reactions, and inflammation. Although very infrequent, allergic reactions have been reported. Conventional hyaluronic acid injectables contain a substance called a cross-linking agent.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">In addition, the high safety profile of <strong> Profhilo has been mentioned in several research papers. <\/strong><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Based on three years of post-market experience, the safety profile of the medical device in this study is favorable.<\/p>\n<cite><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7327616\/\">Daniel Cassuto, et al. (2020) Safety Assessment of High- and Low-Molecular-Weight Hyaluronans (Profhilo\u00ae) as Derived from Worldwide Postmarketing Data. Biomed Res Int.<\/a><\/cite><\/blockquote>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Smart Skin Clinic's Profhilo consistently earns high ratings in reviews on Google, Hot Pepper, KireiPass, and more<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">At Smart Skin Clinic, we think carefully about what our patients truly need and thoroughly cut out unnecessary costs, allowing us to deliver affordability, high quality, and high satisfaction all at once.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a result,<strong><span class=\"swl-marker mark_yellow\">we earn high ratings across a variety of review sites, including Google and Hot Pepper Beauty.<\/span><\/strong>we have earned.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">As a result, about 80% of those who visit us once return for repeat treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Google review rating <strong>4.5\/5.0 (97 reviews)<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"787\" height=\"243\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/08\/image-1.png\" alt=\"\" class=\"wp-image-5680\" style=\"width:677px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/08\/image-1.png 787w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/08\/image-1-300x93.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/08\/image-1-768x237.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/08\/image-1-18x6.png 18w\" sizes=\"auto, (max-width: 787px) 100vw, 787px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<p class=\"wp-block-paragraph\">Hot Pepper Beauty rating <strong> 4.57\/5.00<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"779\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df-779x1024.jpg\" alt=\"\" class=\"wp-image-3866\" style=\"width:421px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df-779x1024.jpg 779w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df-228x300.jpg 228w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df-768x1009.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df-9x12.jpg 9w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/hotpepper\u53e3\u30b3\u30df.jpg 1000w\" sizes=\"auto, (max-width: 779px) 100vw, 779px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column\">\n<p class=\"wp-block-paragraph\">KireiPass rating<strong>4.30\/5.00<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"661\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-661x1024.png\" alt=\"\" class=\"wp-image-3867\" style=\"width:357px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-661x1024.png 661w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-194x300.png 194w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-768x1190.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-991x1536.png 991w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df-8x12.png 8w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ad\u30ec\u30a4\u30d1\u30b9\u53e3\u30b3\u30df.png 1080w\" sizes=\"auto, (max-width: 661px) 100vw, 661px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<p class=\"wp-block-paragraph\">Kumapon rating<strong>4.71\/5.00<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"844\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df-844x1024.png\" alt=\"\" class=\"wp-image-3868\" style=\"width:326px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df-844x1024.png 844w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df-247x300.png 247w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df-768x932.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df-10x12.png 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u304f\u307e\u30dd\u30f3\u53e3\u30b3\u30df.png 1080w\" sizes=\"auto, (max-width: 844px) 100vw, 844px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-column\">\n<p class=\"wp-block-paragraph\">Gangnam Unni rating<strong>9.3\/10.0<\/strong><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"898\" height=\"834\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ab\u30f3\u30ca\u30e0\u30aa\u30f3\u30cb\u53e3\u30b3\u30df-65e9ca3f0a70d.jpg\" alt=\"\" class=\"wp-image-3870\" style=\"width:443px;height:auto\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ab\u30f3\u30ca\u30e0\u30aa\u30f3\u30cb\u53e3\u30b3\u30df-65e9ca3f0a70d.jpg 898w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ab\u30f3\u30ca\u30e0\u30aa\u30f3\u30cb\u53e3\u30b3\u30df-65e9ca3f0a70d-300x279.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ab\u30f3\u30ca\u30e0\u30aa\u30f3\u30cb\u53e3\u30b3\u30df-65e9ca3f0a70d-768x713.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/\u30ab\u30f3\u30ca\u30e0\u30aa\u30f3\u30cb\u53e3\u30b3\u30df-65e9ca3f0a70d-13x12.jpg 13w\" sizes=\"auto, (max-width: 898px) 100vw, 898px\" \/><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n<div style=\"height:39px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_shiny\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">A price comparison between the usual fees at clinics in the Kanto region and Smart Skin Clinic<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Typical going rate<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">At aesthetic clinics in the Kanto region, the market rate for injecting Profhilo into the face is around 65,000\u201380,000 yen per session, 130,000\u2013170,000 yen for a set of two, and about 200,000 yen for three.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">*Surveyed in February 2024.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Smart Skin Clinic's Profhilo injection price, among the most affordable in Japan<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">At Smart Skin Clinic, through thorough cost-reduction and other efforts, we maintain prices that are among the most affordable in Japan.<\/p>\n\n\n\n<!-- \u795e\u4fdd\u753a\u671f\u9593\u9650\u5b9a\u7279\u5225\u4fa1\u683c | \u30b9\u30de\u30fc\u30c8\u30b9\u30ad\u30f3\u30af\u30ea\u30cb\u30c3\u30af  v2 (2025-08-16) -->\r\n<style>\r\n:root{\r\n  --border:#e1e6ef; --header-bg:#f4f6fb; --radius:8px; --fz-base:15px;\r\n  --gold-grad:linear-gradient(90deg,#f8e39a 0%,#e4cc7a 28%,#d1b764 55%,#b79b56 82%,#8c6f2b 100%);\r\n  --gold-ink:#6e5418;      \/* \u7279\u5225\u4fa1\u683c\u306e\u6587\u5b57\u8272\uff08\u6fc3\u3044\u91d1\u3067\u53ef\u8aad\u6027UP\uff09 *\/\r\n  --muted:#6b7280; --text:#0f2747;\r\n}\r\n.pricing-wrapper{width:100%;margin:0 auto 32px;}\r\n.pricing-block{margin:0 0 40px;}\r\n.pricing-title{\r\n  margin:0; padding:.7rem 1rem; font-weight:800; font-size:1.15rem; line-height:1;\r\n  border-top-left-radius:var(--radius); border-top-right-radius:var(--radius);\r\n  display:flex; align-items:center; gap:.5rem; color:#3a2a00; background:var(--gold-grad);\r\n  box-shadow:0 4px 12px rgba(0,0,0,.12);\r\n}\r\n.badge{display:inline-flex;align-items:center;gap:.35em;padding:.18rem .55rem;border-radius:999px;\r\n  font-size:.75rem;font-weight:800;background:#fff;color:#6a520f;border:1px solid rgba(183,155,86,.5);}\r\n.pricing-sub{font-size:.9rem;color:var(--muted);font-weight:600}\r\n\r\n.pricing-table{width:100%;border-collapse:collapse;font-size:var(--fz-base);}\r\n.pricing-table th,.pricing-table td{\r\n  padding:.75rem 1rem;border:1px solid var(--border);text-align:left;white-space:nowrap;\r\n}\r\n.pricing-table thead th{background:var(--header-bg);font-weight:700;color:#000;border-top:1px solid var(--border);}\r\n\r\n\/* \u8996\u8a8d\u6027\uff1a\u901a\u5e38\u4fa1\u683c\u306f\u53d6\u308a\u6d88\u3057\u7dda\uff06\u30b0\u30ec\u30fc\u3001\u7279\u5225\u4fa1\u683c\u306f\u91d1\u8272\u5f37\u8abf\uff083\u5217\u76ee\uff09 *\/\r\n.was{color:var(--muted); text-decoration:line-through;}\r\n.pricing-table td:nth-child(3){color:var(--gold-ink); font-weight:800;}\r\n\r\n\/* \u30b9\u30de\u30db\u6700\u9069\u5316 *\/\r\n@media(max-width:480px){\r\n  :root{--fz-base:14px;}\r\n  .pricing-wrapper{padding:0 0 24px;}\r\n  .pricing-table{display:table;width:100%;table-layout:fixed;overflow-x:visible;}\r\n  .pricing-table th,.pricing-table td{white-space:normal;}\r\n}\r\n<\/style>\r\n\r\n<div class=\"pricing-wrapper\">\r\n\r\n  <section class=\"pricing-block\">\r\n    <div class=\"pricing-title\">\r\n      Jimbocho Limited-Time Special Price\r\n      <span class=\"badge\">Jimbocho Only<\/span>\r\n      <span class=\"badge\">Limited Time<\/span>\r\n    <\/div>\r\n\r\n    <table class=\"pricing-table\">\r\n      <thead>\r\n        <tr>\r\n          <th>Sessions<\/th>\r\n          <th>Regular Price<\/th>\r\n          <th>Special Price<\/th>\r\n          <th>per vial<\/th>\r\n        <\/tr>\r\n      <\/thead>\r\n      <tbody>\r\n        <tr>\r\n          <td>1 session (2cc)<\/td>\r\n          <td class=\"was\">52,800 yen<\/td>\r\n          <td>49,800 yen<\/td>\r\n          <td>49,800 yen<\/td>\r\n        <\/tr>\r\n        <tr>\r\n          <td>Set of 2 (2cc x 2)<\/td>\r\n          <td class=\"was\">99,600 yen<\/td>\r\n          <td>95,600 yen<\/td>\r\n          <td>47,800 yen<\/td>\r\n        <\/tr>\r\n        <tr>\r\n          <td>Set of 3 (2cc x 3)<\/td>\r\n          <td class=\"was\">139,800 yen<\/td>\r\n          <td>137,400 yen<\/td>\r\n          <td>\u00a545,800<\/td>\r\n        <\/tr>\r\n      <\/tbody>\r\n    <\/table>\r\n\r\n    <div class=\"pricing-sub\" style=\"padding:0 1rem;margin-top:.4rem;\">\r\n      * Special price at the Jimbocho Clinic. The Yokohama Clinic currently offers 20% off the regular price.\r\n    <\/div>\r\n  <\/section>\r\n\r\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Below, regular prices<\/p>\n\n\n\n<figure class=\"wp-block-table is-all-centered\"><table><tbody><tr><td>1 session (2cc)<\/td><td><s>129,000 yen<\/s> \u2192 <span class=\"swl-inline-color has-swl-deep-01-color\">52,800 yen<\/span><\/td><\/tr><tr><td>Set of 2 (2cc x 2)<\/td><td><s>258,000 yen<\/s> \u2192 <span class=\"swl-inline-color has-swl-deep-01-color\">99,600 yen<\/span><br>(1st vial <span class=\"swl-inline-color has-swl-main-color\">52,800 yen<\/span>)<br><strong>(<\/strong>2nd vial<strong> <\/strong><span class=\"swl-inline-color has-swl-deep-01-color\">46,800 yen<\/span><strong>)<\/strong><\/td><\/tr><tr><td>Set of 3 (2cc x 3)<\/td><td><s>258,000 yen<\/s> \u2192 <span class=\"swl-inline-color has-swl-deep-01-color\">139,800 yen<\/span><br>(52,800 yen for the 1st vial)<br>(46,800 yen for the 2nd vial)<br>(3rd vial<span class=\"swl-inline-color has-swl-deep-01-color\">40,200 yen<\/span>)<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">*All prices include tax.<br>*We offer self-pay (non-insured) treatments only; insurance does not apply.<br>*Profhilo uses a set of designated injection points known as the BAP technique (treatment at bio-aesthetic points), so at essentially any clinic 2cc covers the treatment area described above.<\/figcaption><\/figure>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">Prices are shown all-inclusive, covering consultation and needle fees.<br>There is no separate upselling on the day.<\/p>\n<\/div><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"16629\">\n<style data-wp-block-html=\"css\">\n\/* \u9ebb\u9154\u8868\u793a\u30d6\u30ed\u30c3\u30af\uff3b\u9ebb\u9154\u306a\u3057\uff3d\n   \u8a2d\u7f6e\u5148\uff1a\u30d6\u30ed\u30b0\u30d1\u30fc\u30c4\u300c\u9ebb\u9154_\u306a\u3057\u300d\u2192 \u30ab\u30b9\u30bf\u30e0HTML\u30d6\u30ed\u30c3\u30af \u2192 CSS\u30bf\u30d6\n   \u5f71\u97ff\u7bc4\u56f2\uff1a\u5168\u30bb\u30ec\u30af\u30bf\u304c .ssc-anes-no \u914d\u4e0b\u3002\u30d6\u30ed\u30c3\u30af\u306e\u5916\u306b\u306f\u4e00\u5207\u5f71\u97ff\u3057\u307e\u305b\u3093 *\/\n\n.ssc-anes-no {\n  box-sizing: border-box;\n  margin: 26px 0 48px;\n  padding: 16px 0;\n  border-top: 1px solid #E2E2E2;\n  border-bottom: 1px solid #E2E2E2;\n}\n\n.ssc-anes-no *,\n.ssc-anes-no *::before,\n.ssc-anes-no *::after {\n  box-sizing: border-box;\n}\n\n.ssc-anes-no .ssc-anes-no__head {\n  margin: 0;\n  padding: 0;\n  font-size: 15px;\n  font-weight: 700;\n  line-height: 1.6;\n  color: #1B1B1B;\n}\n\n.ssc-anes-no .ssc-anes-no__label {\n  font-size: 12.5px;\n  font-weight: 500;\n  color: #767676;\n}\n\n.ssc-anes-no .ssc-anes-no__sep {\n  margin: 0 8px;\n  font-size: 12.5px;\n  font-weight: 400;\n  color: #C8C8C8;\n}\n\n.ssc-anes-no .ssc-anes-no__body {\n  margin: 10px 0 0;\n  padding: 0;\n  font-size: 14px;\n  font-weight: 400;\n  line-height: 1.95;\n  color: #333333;\n}\n\n@media (min-width: 768px) {\n  .ssc-anes-no {\n    margin: 30px 0 56px;\n    padding: 18px 0;\n  }\n\n  .ssc-anes-no .ssc-anes-no__head {\n    font-size: 16px;\n  }\n\n  .ssc-anes-no .ssc-anes-no__body {\n    margin-top: 12px;\n    font-size: 14.5px;\n  }\n}\n<\/style>\n\n<div class=\"ssc-anes-no\">\n  <p class=\"ssc-anes-no__head translation-block\"><span class=\"ssc-anes-no__label\">Anesthesia<\/span><span class=\"ssc-anes-no__sep\">\uff5c<\/span>None<\/p>\n  <p class=\"ssc-anes-no__body\">Since this procedure is relatively painless, we perform it without anesthesia. Because there is no waiting time for anesthesia, the total time from when you arrive until you leave is shorter.<\/p>\n<\/div>\n<\/div>\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph translation-block\"><strong>Monitor Requirements<\/strong><br><br>\u2460<strong>Intended Use<\/strong>\uff5cWe may publish your photos on our website, Instagram, and similar media with the eye area concealed, or show them to other patients as treatment examples [please picture typical case photos].<br>\u2461<strong>Procedure<\/strong>\uff5cYou pay the regular price at your first visit, and we refund the difference (between the regular price and the monitor price) when the monitor photos are taken (3 to 7 days after the second treatment).<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_shiny\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Who cannot receive this treatment<\/strong><\/h2>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">Those who are pregnant or breastfeeding<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Those with excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Profhilo injection site<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Risks and Side Effects<\/strong><\/h2>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">At the needle puncture site:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Redness, swelling, pain, edema<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bruising<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Temporary raised bumps<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Downtime<\/strong><\/h2>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">Redness and raised bumps may occur at the injection site, but in most cases they return to normal in about 24 hours.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:23px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Treatment Flow<\/strong><\/h2>\n\n\n\n<div class=\"swell-block-step\" data-num-style=\"circle\">\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Booking<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph\">You can easily book from your smartphone.<\/p>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_solid\" data-align=\"left\" data-id=\"ab461b08\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Reception<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph\">A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Counseling &amp; Examination<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph\">During counseling, please feel free to share any concerns. Rest assured, there is no pushy sales.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Profhilo injection<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph\">After marking is done, we perform the injection while checking in with you as we go.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Aftercare<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph translation-block\">We will provide detailed instructions on how to care for the treated area and what to keep in mind in your daily life. <br> In addition, with a focus on prevention and maintenance, we recommend appropriate home care products\u2014such as oral medications and skincare products\u2014that can help alleviate your concerns.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-step__item\"><div class=\"swell-block-step__number u-bg-main\"><span class=\"__label\">STEP<\/span><\/div><div class=\"swell-block-step__title u-fz-l\">Going Home<\/div><div class=\"swell-block-step__body\">\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div><\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Details<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-table is-all-centered\"><table><tbody><tr><td>Treatment Time<\/td><td>About 15 minutes (not including counseling)<\/td><\/tr><tr><td>Recommended Number &amp; Frequency of Treatments<\/td><td class=\"translation-block\">\u30fbIt is recommended to wait at least 6 weeks and undergo the treatment as a two-session set. <br>\u30fbAfter that, maintenance treatment is recommended about once every six months.<\/td><\/tr><tr><td>Downtime<\/td><td>About 24 hours<\/td><\/tr><tr><td>Treatment on the day of counseling<\/td><td>Available<\/td><\/tr><tr><td>Makeup<\/td><td>Possible right after the treatment<\/td><\/tr><tr><td>Skincare<\/td><td>Possible right after the treatment<\/td><\/tr><tr><td>Shower<\/td><td>Possible from the same day<\/td><\/tr><tr><td>Pain<\/td><td>A slight pricking sensation when the needle is inserted.<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">*Results vary from person to person.<\/figcaption><\/figure>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"swell-block-button blue_ is-style-btn_shiny\" id=\"nayami\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">FAQ<\/h2>\n\n\n\n<dl class=\"swell-block-faq\" data-q=\"col-text\" data-a=\"col-text\">\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">How often and how many times should I receive it?<\/dt><dd class=\"faq_a\"><div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>Results can be gained even from a single session, but for the most effective approach we recommend one of the following.<br>\u2460 Have the first and second sessions one month apart, then continue the same pattern once a year thereafter.<br>\u2461 Have the first and second sessions one month apart, then continue every six months thereafter.<br><br>*Profhilo's skin remodeling effect increases the extracellular matrix and rejuvenates the skin. Without maintenance, the extracellular matrix gradually decreases \"due to aging\" after the treatment reaches its peak. For this reason, we recommend the approach above.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div><\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">Does it hurt?<\/dt><dd class=\"faq_a\"><div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>It varies from person to person. We use a fine needle, but you may feel a slight pricking sensation. The center of the face is also said to be more sensitive to pain.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div><\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">How long is the downtime?<\/dt><dd class=\"faq_a\"><div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>Redness subsides in about 24 hours.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div><\/dd><\/div>\n\n\n\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">Is one session effective?<\/dt><dd class=\"faq_a\"><div class=\"swell-block-balloon\"><div class=\"c-balloon -bln-left\" data-col=\"blue\"><div class=\"c-balloon__icon -circle\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/09\/1-1-150x150.jpg\" alt=\"\" class=\"c-balloon__iconImg\" width=\"80px\" height=\"80px\"><span class=\"c-balloon__iconName\">Dr. Ishii<\/span><\/div><div class=\"c-balloon__body -speaking -border-none\"><div class=\"c-balloon__text\">\n<p>Results can be gained in a single session, and the lifting effect can be felt right away. That said, many people notice the effects from 3 to 4 weeks later, as skin remodeling progresses.<\/p>\n<span class=\"c-balloon__shapes\"><span class=\"c-balloon__before\"><\/span><span class=\"c-balloon__after\"><\/span><\/span><\/div><\/div><\/div><\/div><\/dd><\/div>\n<\/dl>\n\n\n\n<div style=\"height:59px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Introducing other injectable treatments at Smart Skin Clinic for those with skin-quality concerns<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to Profhilo injections, Smart Skin Clinic also offers other injection treatments that are effective for improving skin quality.<\/p>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"884\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2-884x1024.jpg\" alt=\"\" class=\"wp-image-4133\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2-884x1024.jpg 884w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2-259x300.jpg 259w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2-768x890.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2-10x12.jpg 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/2-2-2.jpg 1000w\" sizes=\"auto, (max-width: 884px) 100vw, 884px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"879\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5-879x1024.jpg\" alt=\"\" class=\"wp-image-4134\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5-879x1024.jpg 879w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5-258x300.jpg 258w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5-768x895.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5-10x12.jpg 10w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/03\/3-5.jpg 1000w\" sizes=\"auto, (max-width: 879px) 100vw, 879px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">If you are interested in the Juvelook injection shown in the case photo above, please refer to the link below.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/smartskin-clinic.com\/campaign-suiko\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Legal Notices<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Profhilo treatment includes procedures using medications or medical devices not approved in Japan. The medications and devices used are personally imported at the discretion of our clinic's physicians.<br><br>Please refer to this page for information on medications and similar items that require caution in personal importation.<br><a href=\"https:\/\/www.mhlw.go.jp\/topics\/bukyoku\/iyaku\/kojinyunyu\/050609-1.html\">Ministry of Health, Labour and Welfare, \"Medications and Similar Items That Require Caution in Personal Importation.\"<\/a><\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"swell-block-button is-style-btn_shiny\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-profhilo\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<p class=\"has-text-align-center sp_only wp-block-paragraph\"><span style=\"font-size:18px\" class=\"swl-fz\"><strong>Smart Skin Clinic<\/strong><\/span><\/p>\n\n\n\n<p class=\"has-text-align-center pc_only wp-block-paragraph\"><span style=\"font-size:30px\" class=\"swl-fz\">Smart Skin Clinic<\/span><\/p>\n\n\n\n<div style=\"height:3px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A clinic built on the concept of \"making aesthetic medicine more accessible and smart.\"<br><br>Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.<br><br>We aim to \"make aesthetic medicine more accessible\" for you.<\/p>\n\n\n<div class=\"wp-block-image is-style-shadow\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"690\" height=\"520\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/07\/26-1.jpg\" alt=\"Clinic Reception\" class=\"wp-image-1179\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/07\/26-1.jpg 690w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/07\/26-1-300x226.jpg 300w\" sizes=\"auto, (max-width: 690px) 100vw, 690px\" \/><\/figure>\n<\/div>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide animated fadeInUp\"\/>\n\n\n\n<p class=\"sp_only wp-block-paragraph translation-block\">Address: <span style=\"font-size:16px\" class=\"swl-fz\">EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo<\/span><br>Specialties: Aesthetic Dermatology (aesthetic dermatology, medical hair removal, medical body contouring)<\/p>\n\n\n\n<p class=\"pc_only wp-block-paragraph translation-block\">Address: <span style=\"font-size:16px\" class=\"swl-fz\">EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo<\/span><br>Specialties: Aesthetic Dermatology (aesthetic dermatology, medical hair removal, medical body contouring)<\/p>\n\n\n\n<div style=\"height:76px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center sp_only wp-block-paragraph\">About the physician supervision of this site<\/p>\n\n\n\n<p class=\"has-text-align-center pc_only wp-block-paragraph\"><span style=\"font-size:26px\" class=\"swl-fz\">About the physician supervision of this site<\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"font-size:20px\" class=\"swl-fz\">This site is operated under the supervision of Smart Skin Clinic's supervising physicians.<\/span><\/strong><\/p>\n\n\n\n<p class=\"sp_only wp-block-paragraph\">This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.<\/p>\n\n\n\n<p class=\"pc_only wp-block-paragraph\"><span style=\"font-size:18px\" class=\"swl-fz\">This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.<\/span><\/p>\n\n\n\n<div style=\"height:67px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b\uff1a\u79c1\u9054\u3082\u30b7\u30ef\u306b\u60a9\u3093\u3067\u304d\u307e\u3057\u305f \u300c\u93e1\u3092\u898b\u308b\u305f\u3073\u306b\u3001\u9854\u3084\u9996\u306e\u30b7\u30ef\u304c\u6c17\u306b\u306a\u308b\u2026\u300d \u305d\u3093\u306a\u601d\u3044\u3092\u62b1\u3048\u3066\u3044\u307e\u305b\u3093 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"swell_btn_cv_data":"{\"ab461b08\":{\"pv\":8700,\"imp\":1432,\"click\":14}}","footnotes":""},"class_list":["post-4996","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/4996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=4996"}],"version-history":[{"count":20,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/4996\/revisions"}],"predecessor-version":[{"id":16892,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/4996\/revisions\/16892"}],"wp:attachment":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=4996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}