{"id":6489,"date":"2024-11-04T15:56:56","date_gmt":"2024-11-04T06:56:56","guid":{"rendered":"https:\/\/smartskin-clinic.com\/?page_id=6489"},"modified":"2026-09-06T15:12:09","modified_gmt":"2026-09-06T06:12:09","slug":"prp-forehead","status":"publish","type":"page","link":"https:\/\/smartskin-clinic.com\/en\/menu\/prp-forehead\/","title":{"rendered":"What Are Personalized PRP Injections (for Forehead Wrinkles and Hollows)? | A Doctor Explains the Effects, Costs, and Downtime"},"content":{"rendered":"<div class=\"swell-block-fullWide pc-py-0 sp-py-0 alignfull\" style=\"background-color:#f7f7f7\"><div class=\"swell-block-fullWide__inner\">\n<figure class=\"wp-block-image size-full is-resized u-lb-off\"><img loading=\"lazy\" decoding=\"async\" width=\"780\" height=\"1300\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3.jpg\" alt=\"\" class=\"wp-image-6866\" style=\"width:500px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3.jpg 780w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3-180x300.jpg 180w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3-614x1024.jpg 614w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3-768x1280.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/01\/3-7x12.jpg 7w\" sizes=\"auto, (max-width: 780px) 100vw, 780px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10876\">\n<style>\n  .price-campaign-banner {\n    background: #fefefe;\n    border: 1px solid #d4af37;\n    border-left: 6px solid #d4af37;\n    border-radius: 10px;\n    padding: 25px;\n    font-family: 'Noto Serif JP', serif;\n    color: #4a4a4a;\n    box-shadow: 0 2px 6px rgba(0, 0, 0, 0.05);\n    max-width: 800px;\n    margin: 40px auto;\n    text-align: left;\n  }\n\n  .price-campaign-banner .title {\n    font-size: 20px;\n    font-weight: bold;\n    color: #9C505F;\n    margin-bottom: 12px;\n  }\n\n  .price-campaign-banner .body {\n    font-size: 16px;\n    line-height: 1.7;\n    color: #4a4a4a;\n  }\n\n  .price-campaign-banner .highlight {\n    color: #d2232a;\n    font-weight: bold;\n    font-size: 18px;\n  }\n\n  .price-campaign-banner .period {\n    margin-top: 15px;\n    font-size: 15px;\n    background: #fff8e5;\n    padding: 8px 12px;\n    border-radius: 6px;\n    display: inline-block;\n    font-weight: bold;\n    color: #9C505F;\n  }\n\n  @media (max-width: 768px) {\n    .price-campaign-banner {\n      padding: 20px;\n    }\n\n    .price-campaign-banner .title {\n      font-size: 18px;\n    }\n\n    .price-campaign-banner .body {\n      font-size: 15px;\n    }\n\n    .price-campaign-banner .highlight {\n      font-size: 16px;\n    }\n  }\n<\/style>\n\n<div class=\"price-campaign-banner\">\n  <p class=\"title translation-block\">Personalized PRP Injection <strong>20% OFF<\/strong> Now On<\/p>\n  <p class=\"body translation-block\">We are currently running a campaign in which <span class=\"highlight\">all areas are 20% OFF<\/span> the regular price.<\/p>\n  <p class=\"period\">Campaign Period: December 1, 2025 \u2013 November 30, 2026<\/p>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-personalizedprp\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10904\">\n<div class=\"swell-block-button -size-l is-style-btn_solid\"><a href=\"tel:050-1720-6230\" class=\"swell-block-button__link\"><span>Book by phone here<br>050-1720-6230<\/span><\/a><\/div>\n<\/div>\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">\"I've heard PRP injections are effective for forehead wrinkles, but are they really effective? How safe is it?\"<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\"I've heard that injections combining PRP with FGF can be risky, but what's the truth?\"<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\"I just want to improve the wrinkles and indentations on my forehead.\"<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\"I want to do something about my forehead wrinkles, so I've been comparing options like Botox injections and hyaluronic acid filler. But I'm wondering if there's a way to do it without losing my natural expression...\"<\/p>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Hello, I'm a physician at Smart Skin Clinic, a cosmetic dermatology clinic. Do any of these questions or concerns sound familiar?<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">In this article, a cosmetic dermatology clinic\u2014which is a <span class=\"swl-marker mark_blue\"><strong>Ministry of Health, Labor and Welfare-certified facility for regenerative medicine provision plans<\/strong><\/span>\u2014will provide an easy-to-understand explanation from a professional perspective. (*Certification Numbers for Type II and Type III Regenerative Medicine Provision Plans: NA8230001)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">*If you'd like to know the prices, you can jump to the relevant section from the table of contents below.<\/p>\n\n\n\n<!-- ======================================\n     \u76e3\u4fee\u8005\u60c5\u5831 \u2013 Smart Skin Clinic\n     Brand Colors: #ffffff #000000 #f5f5f5 #a3e3fc\n====================================== -->\n<section class=\"ssc-supervisor\">\n\n  <!-- \u76e3\u4fee\u8005\u60c5\u5831\u30bf\u30a4\u30c8\u30eb -->\n  <div class=\"ssc-supervisor-title-wrapper\">\n    <span class=\"ssc-supervisor-title\">Supervisor Information<\/span>\n  <\/div>\n\n  <div class=\"ssc-supervisor-inner\">\n\n    <!-- \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f -->\n    <div class=\"ssc-supervisor-photo\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg\" alt=\"Kota Ishii, Chief Medical Director, Smart Skin Clinic Group\" loading=\"lazy\" \/>\n    <\/div>\n\n    <!-- \u30c6\u30ad\u30b9\u30c8\u60c5\u5831 -->\n    <div class=\"ssc-supervisor-text\">\n\n      <p class=\"ssc-supervisor-role\">Group Chief Director, Smart Skin Clinic Group<\/p>\n      <p class=\"ssc-supervisor-name translation-block\"><ruby>Ishii<rt>Ishii<\/rt><\/ruby> <ruby>Kota<rt>Kota<\/rt><\/ruby><\/p>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Career<\/h4>\n        <p>Graduated from Juntendo University School of Medicine<\/p>\n        <p>Worked at Tokyo Women's Medical University Hospital and affiliated facilities<\/p>\n        <p>Worked at a major aesthetic clinic in Tokyo<\/p>\n      <\/div>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Affiliations \/ Qualifications<\/h4>\n        <p>Board-certified specialist, Japan Surgical Society<\/p>\n        <p>Board-certified specialist, Japanese Society of Anti-Aging Medicine<\/p>\n      <\/div>\n\n    <\/div><!-- \/.text -->\n  <\/div><!-- \/.inner -->\n<\/section>\n\n<style>\n\/* =========================================================\n  Smart Skin Clinic \u2013 Supervisor Component (Monotone + Water)\n========================================================= *\/\n\n\/* \u25c7 \u30d1\u30ec\u30c3\u30c8 *\/\n:root{\n  --ssc-black:#000000;\n  --ssc-white:#ffffff;\n  --ssc-gray:#f5f5f5;\n  --ssc-water:#a3e3fc;   \/* \u30a2\u30af\u30bb\u30f3\u30c8\u6c34\u8272 *\/\n}\n\n\/* \u30bb\u30af\u30b7\u30e7\u30f3 *\/\n.ssc-supervisor{\n  background:var(--ssc-gray);\n  padding:40px 5%;\n  border:1px solid #e0e0e0;\n  border-radius:8px;\n  margin:40px 0;\n  color:var(--ssc-black);\n  font-family:\"Noto Sans JP\",\"Hiragino Sans\",\"Helvetica Neue\",Arial,sans-serif;\n}\n\n\/* \u30bf\u30a4\u30c8\u30eb *\/\n.ssc-supervisor-title-wrapper {\n  font-size: 1.5rem;\n  font-weight: 700;\n  margin: 0 0 24px;\n  display: flex;\n  align-items: flex-end;\n  gap: 8px;\n  color: var(--ssc-black);\n}\n\n.ssc-supervisor-title {\n  font-size: 1.5rem;\n  font-weight: 700;\n  color: var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30ec\u30a4\u30a2\u30a6\u30c8 *\/\n.ssc-supervisor-inner{\n  display:flex;\n  gap:28px;\n  flex-wrap:wrap;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8 *\/\n.ssc-supervisor-text{\n  flex:1 1 260px;\n  min-width:260px;\n}\n.ssc-supervisor-role{\n  font-size:0.9rem;\n  color:var(--ssc-black);  \/* \u9ed2\u6587\u5b57\u306b\u4fee\u6b63 *\/\n  margin:0 0 4px;\n}\n.ssc-supervisor-name{\n  font-size:1.25rem;\n  font-weight:700;\n  margin:0 0 16px;\n  background-color:transparent;  \/* \u80cc\u666f\u306e\u8272\u3092\u900f\u660e\u306b\u8a2d\u5b9a *\/\n  color:var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30d6\u30ed\u30c3\u30af *\/\n.ssc-supervisor-block{\n  margin-bottom:18px;\n}\n.ssc-supervisor-block h4{\n  font-size:1rem;\n  font-weight:600;\n  margin:0 0 6px;\n  color:var(--ssc-black);\n  border-left:4px solid var(--ssc-water);\n  padding-left:8px;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8\u8868\u793a\u306e\u5909\u66f4\uff08\u7b87\u6761\u66f8\u304d\u306f\u4f7f\u7528\u305b\u305a\u3001\u30b7\u30f3\u30d7\u30eb\u306b\u8868\u793a\uff09 *\/\n.ssc-supervisor-block p{\n  font-size:1rem;\n  margin: 0 0 10px;\n  color: var(--ssc-black);\n  line-height: 1.6;\n}\n\n\/* \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f *\/\n.ssc-supervisor-photo{\n  flex:0 0 190px;\n  max-width:190px;\n}\n.ssc-supervisor-photo img{\n  width:100%;\n  height:auto;\n  display:block;\n  border-radius:8px;\n}\n\n\/* \u30b9\u30de\u30db *\/\n@media(max-width:600px){\n  .ssc-supervisor-inner{\n    flex-direction:column;\n    gap:20px;\n  }\n  .ssc-supervisor-photo{\n    flex:0 0 auto;\n    max-width:150px;\n    margin:0 auto;\n  }\n}\n<\/style>\n\n\n\n<h2 class=\"wp-block-heading\">What Is Personalized PRP Injection?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">PRPF injections are a treatment <\/span><\/strong> that involves injecting a preparation of <strong><span class=\"swl-marker mark_blue\">PRP (platelet-rich plasma) to which FGF (fibroblast growth factor) has been added<\/span><\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PRP: An ingredient extracted from your own blood, rich in growth factors <br>FGF: Fibroblast growth factor. An ingredient that powerfully promotes skin regeneration<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By combining these two, the treatment is said to have a greater effect on the dermis than conventional PRP therapy.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Case Photos (Before\/After)<\/h2>\n\n\n\n<!-- Smart Skin Clinic \u75c7\u4f8b Before\/After \u2013 \u30ab\u30b9\u30bf\u30e0HTML \u5b8c\u5168\u7248 -->\n\n<style>\n\n.ssc-ba-wrap{\n\n  --before-bg:#e6e6e6; --before-color:#444;\n\n  --after-bg:#a3e3fc;   \/* \u30d6\u30e9\u30f3\u30c9\u30ab\u30e9\u30fc *\/\n\n  --after-color:#0a2838;\/* \u767d\u3088\u308a\u8996\u8a8d\u6027\u306e\u9ad8\u3044\u6fc3\u7d3a\u7cfb *\/\n\n  --radius:14px; --shadow:0 8px 24px rgba(0,0,0,.08);\n\n  --ar:4\/5; \/* \u753b\u50cf\u6bd4\u7387\uff1a1\/1, 3\/4 \u306a\u3069\u306b\u5909\u66f4\u53ef *\/\n\n  max-width:720px; margin:24px auto;\n\n  font-family:system-ui,-apple-system,\"Hiragino Kaku Gothic ProN\",\"Yu Gothic\",sans-serif;\n\n}\n\n.ssc-ba-card{border-radius:var(--radius); box-shadow:var(--shadow); overflow:hidden; background:#fff;}\n\n.ssc-ba-imgs{display:grid; grid-template-columns:1fr 1fr;}\n\n.ssc-ba-imgs img{width:100%; height:auto; aspect-ratio:var(--ar); object-fit:cover; display:block;}\n\n.ssc-ba-caption{display:grid; grid-template-columns:1fr 1fr; font-weight:600; letter-spacing:.06em; font-size:14px; line-height:1;}\n\n.ssc-ba-caption span{padding:14px 10px; text-align:center;}\n\n.ssc-ba-caption .before{background:var(--before-bg); color:var(--before-color);}\n\n.ssc-ba-caption .after{background:var(--after-bg); color:var(--after-color);}\n\n\n\n\/* \u2500\u2500 \u30b9\u30de\u30db\uff1a\u5de6\u53f3\u4f59\u767d\u3092\u30d3\u30e5\u30fc\u30dd\u30fc\u30c8\u57fa\u6e96\u3067\u201c\u5747\u7b49\u306b\u201d\u56fa\u5b9a \u2500\u2500 *\/\n\n@media (max-width:600px){\n\n  .ssc-ba-wrap{\n\n    --gutter:0.8cm; \/* \u7247\u5074\u306e\u4f59\u767d\u30020.7\u20131.0cm\u3067\u8abf\u6574OK *\/\n\n    --safeL: env(safe-area-inset-left, 0px);\n\n    --safeR: env(safe-area-inset-right, 0px);\n\n\n\n    \/* \u89aa\u306e\u30d1\u30c7\u30a3\u30f3\u30b0\u306b\u5f71\u97ff\u3055\u308c\u305a\u3001\u5de6\u53f3\u3068\u3082\u540c\u3058\u898b\u3048\u65b9\u306b *\/\n\n    max-width:none; width:auto; box-sizing:border-box;\n\n    margin-left:  calc(50% - 50vw + max(var(--gutter), var(--safeL)));\n\n    margin-right: calc(50% - 50vw + max(var(--gutter), var(--safeR)));\n\n  }\n\n  .ssc-ba-caption span{padding:12px 8px; font-size:12px;}\n\n}\n\n<\/style>\n\n\n\n<div class=\"ssc-ba-wrap\">\n\n  <figure class=\"ssc-ba-card\" role=\"group\" aria-label=\"Before\/After\">\n\n    <div class=\"ssc-ba-imgs\">\n\n      <img src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/08\/\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30baPRP_Before_50\u4ee3\u7537\u6027.webp\" alt=\"Before treatment\" loading=\"lazy\" decoding=\"async\">\n\n      <img src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/08\/\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30baPRP_3\u30f6\u6708\u5f8c_50\u7b2c\u7537\u6027.webp\"  alt=\"After treatment\" loading=\"lazy\" decoding=\"async\">\n\n    <\/div>\n\n    <figcaption class=\"ssc-ba-caption\" aria-hidden=\"true\">\n\n      <span class=\"before\">BEFORE<\/span>\n\n      <span class=\"after\">AFTER<\/span>\n\n    <\/figcaption>\n\n  <\/figure>\n\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">This is a case study of a man in his 50s who received personalized PRP injections three months ago. <br> We designed the treatment plan based on an assessment of his entire face and administered the injections in a customized manner to the areas with wrinkles.<\/p>\n\n\n\n<!-- Smart Skin Clinic \u75c7\u4f8b Before\/After \u2013 \u30ab\u30b9\u30bf\u30e0HTML \u5b8c\u5168\u7248 -->\n\n<style>\n\n.ssc-ba-wrap{\n\n  --before-bg:#e6e6e6; --before-color:#444;\n\n  --after-bg:#a3e3fc;   \/* \u30d6\u30e9\u30f3\u30c9\u30ab\u30e9\u30fc *\/\n\n  --after-color:#0a2838;\/* \u767d\u3088\u308a\u8996\u8a8d\u6027\u306e\u9ad8\u3044\u6fc3\u7d3a\u7cfb *\/\n\n  --radius:14px; --shadow:0 8px 24px rgba(0,0,0,.08);\n\n  --ar:4\/5; \/* \u753b\u50cf\u6bd4\u7387\uff1a1\/1, 3\/4 \u306a\u3069\u306b\u5909\u66f4\u53ef *\/\n\n  max-width:720px; margin:24px auto;\n\n  font-family:system-ui,-apple-system,\"Hiragino Kaku Gothic ProN\",\"Yu Gothic\",sans-serif;\n\n}\n\n.ssc-ba-card{border-radius:var(--radius); box-shadow:var(--shadow); overflow:hidden; background:#fff;}\n\n.ssc-ba-imgs{display:grid; grid-template-columns:1fr 1fr;}\n\n.ssc-ba-imgs img{width:100%; height:auto; aspect-ratio:var(--ar); object-fit:cover; display:block;}\n\n.ssc-ba-caption{display:grid; grid-template-columns:1fr 1fr; font-weight:600; letter-spacing:.06em; font-size:14px; line-height:1;}\n\n.ssc-ba-caption span{padding:14px 10px; text-align:center;}\n\n.ssc-ba-caption .before{background:var(--before-bg); color:var(--before-color);}\n\n.ssc-ba-caption .after{background:var(--after-bg); color:var(--after-color);}\n\n\n\n\/* \u2500\u2500 \u30b9\u30de\u30db\uff1a\u5de6\u53f3\u4f59\u767d\u3092\u30d3\u30e5\u30fc\u30dd\u30fc\u30c8\u57fa\u6e96\u3067\u201c\u5747\u7b49\u306b\u201d\u56fa\u5b9a \u2500\u2500 *\/\n\n@media (max-width:600px){\n\n  .ssc-ba-wrap{\n\n    --gutter:0.8cm; \/* \u7247\u5074\u306e\u4f59\u767d\u30020.7\u20131.0cm\u3067\u8abf\u6574OK *\/\n\n    --safeL: env(safe-area-inset-left, 0px);\n\n    --safeR: env(safe-area-inset-right, 0px);\n\n\n\n    \/* \u89aa\u306e\u30d1\u30c7\u30a3\u30f3\u30b0\u306b\u5f71\u97ff\u3055\u308c\u305a\u3001\u5de6\u53f3\u3068\u3082\u540c\u3058\u898b\u3048\u65b9\u306b *\/\n\n    max-width:none; width:auto; box-sizing:border-box;\n\n    margin-left:  calc(50% - 50vw + max(var(--gutter), var(--safeL)));\n\n    margin-right: calc(50% - 50vw + max(var(--gutter), var(--safeR)));\n\n  }\n\n  .ssc-ba-caption span{padding:12px 8px; font-size:12px;}\n\n}\n\n<\/style>\n\n\n\n<div class=\"ssc-ba-wrap\">\n\n  <figure class=\"ssc-ba-card\" role=\"group\" aria-label=\"Before\/After\">\n\n    <div class=\"ssc-ba-imgs\">\n\n      <img src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/08\/\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30baPRP_50\u4ee3\u5973\u6027_\u9854\u5168\u4f53_Before.webp\" alt=\"Before treatment\" loading=\"lazy\" decoding=\"async\">\n\n      <img src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/08\/\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30baPRP_50\u4ee3\u5973\u6027_\u9854\u5168\u4f53_After.webp\"  alt=\"After treatment\" loading=\"lazy\" decoding=\"async\">\n\n    <\/div>\n\n    <figcaption class=\"ssc-ba-caption\" aria-hidden=\"true\">\n\n      <span class=\"before\">BEFORE<\/span>\n\n      <span class=\"after\">AFTER<\/span>\n\n    <\/figcaption>\n\n  <\/figure>\n\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">This is a case study of a woman in her 50s who received personalized PRP injections three months ago. <br> We designed the treatment plan based on an assessment of her entire face and administered the injections in a customized manner to the areas with wrinkles.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">The Role of Growth Factors<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Growth factors are a general term for proteins and peptides that promote cell growth, division, and differentiation. They have drawn particular attention in aesthetic medicine for the major role they play in skin rejuvenation and regeneration.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Key growth factors include the following:<\/p>\n\n\n\n<ol class=\"wp-block-list is-style-index\">\n<li>EGF (Epidermal Growth Factor): Helps skin regeneration<\/li>\n\n\n\n<li>FGF (Fibroblast Growth Factor): Increases collagen and elastin to plump up the skin<\/li>\n\n\n\n<li>IGF (Insulin-like Growth Factor): Generates new cells and helps reduce damage caused by aging<\/li>\n<\/ol>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Mechanism of Personalized PRP injection: why is it effective for forehead wrinkles?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">PRP injections work on forehead wrinkles mainly through the following five mechanisms:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">1. Promoting Collagen Production<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Platelet-derived growth factor (PDGF) and FGF in PRP stimulate fibroblasts, promoting collagen production and improving the skin's firmness and elasticity. This helps improve the skin laxity that causes forehead wrinkles.<\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">2. Promoting elastin production<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">FGF also promotes elastin production. Elastin is a key protein that maintains skin elasticity, and increasing it helps improve expression lines on the forehead.<\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">3. Improving skin thickness<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">PRP works to thicken the dermal layer of the skin. This makes indentations on the forehead less noticeable and creates an overall more youthful impression.<\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">4. Boosting circulation<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. This improves circulation and activates skin metabolism.<\/p>\n\n\n\n<div style=\"height:45px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">5. Tightens pores and enhances radiance<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The skin-regenerating effect of growth factors also helps tighten pores on the forehead. It also activates cells on the skin's surface, giving the forehead a naturally radiant glow.<\/p>\n\n\n\n<div style=\"height:114px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Three Features of Personalized PRP Injection<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. Natural Rejuvenation Effect<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Because it uses your own cells, the result looks natural. It enhances the skin's own regenerative ability, so it doesn't create the stiff expression sometimes associated with Botox.<\/p>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">2. Personalized Treatment<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">At our clinic, we adjust the concentration and volume of PRP and design each injection individually according to each patient's skin condition and goals.<\/p>\n\n\n\n<div style=\"height:49px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">3. Duration and Cost Performance<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Given the mechanism of PRPF injection, results are achieved by working within the skin itself, so medium- to long-term effects can be expected.<br><span class=\"swl-fz u-fz-s\">*The duration of the effect varies from person to person.<\/span><\/p>\n\n\n\n<div style=\"height:93px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Personalized PRP Injection Is Recommended For<\/h2>\n\n\n\n<ul class=\"wp-block-list is-style-check_list\">\n<li>Those concerned about forehead wrinkles<\/li>\n\n\n\n<li>Those who have started to notice expression lines<\/li>\n\n\n\n<li>Those concerned about indentations on the forehead<\/li>\n\n\n\n<li>Those concerned about enlarged pores on the forehead<\/li>\n\n\n\n<li>Those who want naturally radiant forehead skin<\/li>\n\n\n\n<li>Those who want a natural-looking result<\/li>\n\n\n\n<li>Those worried that Botox might stiffen their facial expression<\/li>\n<\/ul>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Features of Our Personalized PRP Injection<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. A Clinic Specializing in Injectable Treatments<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Our clinic is focused on injectable treatments and has built up extensive knowledge and experience in this field.<br><br>\u30fbInjection techniques designed to minimize pain <br>\u30fbTreatment personalized for each patient<\/p>\n\n\n\n<blockquote class=\"instagram-media\" data-instgrm-permalink=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\"> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">View this post on Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/p\/C1gskFoSzuV\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\">A post shared by Smart Skin Clinic [Aesthetic Dermatology] Jimbocho Juvelook &amp; Profhilo &amp; Sunekos (@smartskin_clinic)<\/a><\/p><\/div><\/blockquote> <script async src=\"\/\/www.instagram.com\/embed.js\"><\/script>\n\n\n\n<div style=\"height:52px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">2. Expertise in Regenerative Medicine<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbA regenerative medicine provider approved by the Ministry of Health, Labour and Welfare (holds a Type 2 Regenerative Medicine Provision Plan number) <br>\u30fbPhysicians certified by the Japanese Society of Anti-Aging Medicine on staff<\/p>\n\n\n\n<div style=\"height:65px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">3. Treatment That Combines Injectable and Regenerative Medicine Expertise<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbDraws on experience in injectable treatments together with regenerative medicine insight <br>\u30fbPersonalized treatment plans tailored to each patient's condition and goals<\/p>\n\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-personalizedprp\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Pricing<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Typical PRPF Injection Prices in Tokyo<\/h3>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">The typical price range for PRPF injections in Tokyo is <strong><span class=\"swl-marker mark_blue\">approximately 200,000 to 400,000 yen<\/span><\/strong>. (As of August 1, 2024)<\/p>\n\n\n\n<div style=\"height:52px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Smart Skin Clinic Price List<\/h3>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10876\">\n<style>\n  .price-campaign-banner {\n    background: #fefefe;\n    border: 1px solid #d4af37;\n    border-left: 6px solid #d4af37;\n    border-radius: 10px;\n    padding: 25px;\n    font-family: 'Noto Serif JP', serif;\n    color: #4a4a4a;\n    box-shadow: 0 2px 6px rgba(0, 0, 0, 0.05);\n    max-width: 800px;\n    margin: 40px auto;\n    text-align: left;\n  }\n\n  .price-campaign-banner .title {\n    font-size: 20px;\n    font-weight: bold;\n    color: #9C505F;\n    margin-bottom: 12px;\n  }\n\n  .price-campaign-banner .body {\n    font-size: 16px;\n    line-height: 1.7;\n    color: #4a4a4a;\n  }\n\n  .price-campaign-banner .highlight {\n    color: #d2232a;\n    font-weight: bold;\n    font-size: 18px;\n  }\n\n  .price-campaign-banner .period {\n    margin-top: 15px;\n    font-size: 15px;\n    background: #fff8e5;\n    padding: 8px 12px;\n    border-radius: 6px;\n    display: inline-block;\n    font-weight: bold;\n    color: #9C505F;\n  }\n\n  @media (max-width: 768px) {\n    .price-campaign-banner {\n      padding: 20px;\n    }\n\n    .price-campaign-banner .title {\n      font-size: 18px;\n    }\n\n    .price-campaign-banner .body {\n      font-size: 15px;\n    }\n\n    .price-campaign-banner .highlight {\n      font-size: 16px;\n    }\n  }\n<\/style>\n\n<div class=\"price-campaign-banner\">\n  <p class=\"title translation-block\">Personalized PRP Injection <strong>20% OFF<\/strong> Now On<\/p>\n  <p class=\"body translation-block\">We are currently running a campaign in which <span class=\"highlight\">all areas are 20% OFF<\/span> the regular price.<\/p>\n  <p class=\"period\">Campaign Period: December 1, 2025 \u2013 November 30, 2026<\/p>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10615\">\n<figure class=\"wp-block-table is-all-centered min_width30_\"><table><tbody><tr><td class=\"has-text-align-left\" data-align=\"left\"><strong>Menu<\/strong><\/td><td class=\"has-text-align-left\" data-align=\"left\"><strong>Regular Price<\/strong><\/td><td class=\"has-text-align-left\" data-align=\"left\"><strong><strong>11\/30<\/strong>Limited-time discount until<\/strong><br><strong><span class=\"swl-marker mark_yellow\">(20% off)<\/span><\/strong><\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">Once<\/td><td class=\"has-text-align-left\" data-align=\"left\"><s>208,000 yen<\/s><\/td><td class=\"has-text-align-left\" data-align=\"left\">166,400 yen<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">Monitor 1 session<\/td><td class=\"has-text-align-left\" data-align=\"left\"><s>178,000 yen<\/s><\/td><td class=\"has-text-align-left\" data-align=\"left\">142,400 yen<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">Second area (face)<\/td><td class=\"has-text-align-left\" data-align=\"left\"><s>166,400 yen<\/s><\/td><td class=\"has-text-align-left\" data-align=\"left\">\u00a5133,120<\/td><\/tr><tr><td class=\"has-text-align-left translation-block\" data-align=\"left\">Monitor<br>Second Area (Face)<\/td><td class=\"has-text-align-left\" data-align=\"left\"><s>136,400 yen<\/s><\/td><td class=\"has-text-align-left\" data-align=\"left\">\u00a5109,120<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">*All prices include tax.<br>*We offer self-pay (non-insured) treatments only; insurance does not apply.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n<\/div>\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\">Prices are shown all-inclusive, covering consultation and needle fees.<br>There is no separate upselling on the day.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\"><strong>Monitor Requirements<\/strong><br><br>\u2460<strong>Intended Use<\/strong>| We may publish the photos on our website, Instagram, and similar media with the eye area concealed, or show them to other patients as treatment examples [please picture typical case photos].<br>\u2461<strong>Procedure<\/strong>\uff5cYou will pay the regular price at your first visit, and the difference (between the regular price and the monitor price) will be refunded when your monitor photos are taken (approximately 3 months after treatment as a guide)<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-personalizedprp\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10904\">\n<div class=\"swell-block-button -size-l is-style-btn_solid\"><a href=\"tel:050-1720-6230\" class=\"swell-block-button__link\"><span>Book by phone here<br>050-1720-6230<\/span><\/a><\/div>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">Comparison with Other Treatments<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. Comparison with Hyaluronic Acid Injection<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbPRPF: Uses ingredients derived from your own body, so allergy risk is low, with long-term skin regeneration benefits <br>\u30fbHyaluronic acid: Provides an immediate volumizing effect, but is absorbed within 6 to 12 months. It also carries a risk of vascular occlusion, requiring caution when injected near blood vessels such as under the eyes or between the brows<\/p>\n\n\n\n<div style=\"height:69px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">2. Comparison with Laser Treatment<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbPRPF: Works deep within the skin for long-lasting results <br>\u30fbLaser: Mainly addresses surface-level concerns and requires multiple sessions<\/p>\n\n\n\n<div style=\"height:81px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">3. Comparison with Surgical Procedures<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbPRPF: Non-invasive with fast recovery and natural-looking results <br>\u30fbSurgical procedures: Can achieve dramatic change, but carry greater risk and downtime<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Personalized PRP Injection Procedure<\/h2>\n\n\n\n<ol class=\"wp-block-list is-style-num_circle\">\n<li>Blood draw: A small amount of blood is drawn from the patient's arm<\/li>\n\n\n\n<li>PRP extraction: PRP is extracted using a specialized centrifuge<\/li>\n\n\n\n<li>FGF addition: FGF is added to the extracted PRP<\/li>\n\n\n\n<li>Injection design: Individually designed to address the specific concerns you want to resolve<\/li>\n\n\n\n<li>Injection: A fine needle is used to inject into the skin under the eyes<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">The needles used are extremely fine, minimizing pain. Anesthetic cream can also be used if needed.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Precautions and Side Effects<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">PRPF injection is relatively safe, but it may cause temporary side effects such as:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30fbMild swelling or bruising at the injection site <br>\u30fbTemporary pain or discomfort<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In rare cases, infection or an inflammatory reaction may occur. At our clinic, strict hygiene protocols and skilled technique help minimize these risks.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">FAQ<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Q1: Is PRPF injection painful?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A1: Because we use an extremely fine needle and can apply anesthetic cream if needed, most patients experience only mild discomfort.<\/p>\n\n\n\n<div style=\"height:21px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Q2: When can I expect to notice results?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A2: Results vary by individual, but most patients begin to notice a gradual effect from around 2 to 4 weeks. The full effect often appears after 3 to 6 months.<\/p>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Summary<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">PRPF injection is an effective treatment for improving forehead wrinkles and indentations. Because it uses your own cells, it is safe and delivers natural-looking results.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At Smart Skin Clinic, we draw on our expertise in both injectable treatments and regenerative medicine to provide personalized PRP injections.<\/p>\n\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/en\/reservation-personalizedprp\/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"swell-block-button__link\"><span>Book a web appointment or free consultation here<\/span><\/a><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10904\">\n<div class=\"swell-block-button -size-l is-style-btn_solid\"><a href=\"tel:050-1720-6230\" class=\"swell-block-button__link\"><span>Book by phone here<br>050-1720-6230<\/span><\/a><\/div>\n<\/div>\n\n<div class=\"p-blogParts post_content\" data-partsid=\"14253\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"650\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA.jpg\" alt=\"\" class=\"wp-image-18918\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA.jpg 2000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-300x98.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-768x250.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-1536x499.jpg 1536w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-18x6.jpg 18w\" sizes=\"auto, (max-width: 2000px) 100vw, 2000px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n\n<div class=\"wp-block-group ssc-eeat\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\n<h2 class=\"wp-block-heading\">Physician Who Supervised This Page<\/h2>\n\n\n\n<div class=\"wp-block-media-text profile is-stacked-on-mobile\" style=\"grid-template-columns:28% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"1920\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg\" alt=\"Kota Ishii, Chief Medical Director, Smart Skin Clinic\" class=\"wp-image-12584 size-full\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg 1280w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-200x300.jpg 200w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-768x1152.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-1024x1536.jpg 1024w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-8x12.jpg 8w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"u-mb-0 wp-block-paragraph\"><span class=\"swl-fz u-fz-s\"><strong>Smart Skin Clinic, Chief Medical Director \/ Physician<\/strong><\/span><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span class=\"swl-fz u-fz-l\">Kota Ishii<\/span><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.<\/p>\n\n\n\n<div class=\"swell-block-button is-style-btn_normal\"><a href=\"https:\/\/smartskin-clinic.com\/en\/concept\/\" class=\"swell-block-button__link\"><span>See the Philosophy of Our Doctors and Clinics<\/span><\/a><\/div>\n<\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Interview with Director Kota Ishii<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"A number of repeat customers for skin growth injections: \u2049\ufe0fAttack on the handsome general director of a popular clinic: \ud83e\uddd1\u200d\u2695\ufe0f\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/u6cP6jPmfwU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div><\/div>\n\n\n\n<!-- \u25bc\u25bc Clinic List \u5171\u901a\u30d1\u30fc\u30c4 \u25bc\u25bc -->\n<section>\n  <!-- \u30bf\u30a4\u30c8\u30eb -->\n  <div class=\"ssc-shoplist-title\">\n    <small>CLINIC LIST<\/small>\n    <h2>Clinic List<\/h2>\n  <\/div>\n  <!-- \u30ab\u30fc\u30c9\u4e00\u89a7 -->\n  <div class=\"ssc-shoplist-grid\">\n    <!-- \u795e\u4fdd\u753a\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/en\/clinics\/jimbocho\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/06\/smart-skin-clinic-jimbocho-reception-waiting-area-.webp\" alt=\"Smart Skin Clinic Jimbocho Clinic Reception and Waiting Area\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Jimbocho Clinic<\/p>\n        <p>\u3012101-0054<br>3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) \/ 7F<\/p>\n        <p>Hours: Mon\u2013Fri 11:00\u201320:00 \/ Sat &amp; Sun 10:00\u201319:00<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u6a2a\u6d5c\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/en\/clinics\/yokohama\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/06\/smartskin-clinic-yokohama-lobby-overview.webp\" alt=\"Smart Skin Clinic Yokohama Clinic Reception and Waiting Area Overview\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Yokohama Clinic<\/p>\n        <p>\u3012221-0835<br>TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa<\/p>\n        <p>Hours: 10:00\u201319:00<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u516b\u4e01\u5800\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/en\/clinics\/hatchobori\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/08\/\u516b\u4e01\u5800\u9662_\u53d7\u4ed8\u5f85\u5408.jpg\" alt=\"Smart Skin Clinic Hatchobori Branch: Overview of the Reception and Waiting Area\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Hatchobori Clinic<\/p>\n        <p>104-0032<br>2nd Floor, Tokyo NS Building, 2-29-4 Hatchobori, Chuo-ku, Tokyo<\/p>\n        <p>Hours: 10:00 a.m.\u20137:00 p.m. (Closed from 1:00 p.m. to 2:00 p.m.) \/ Closed: Mondays and Thursdays<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u8ffd\u52a0\u9662\u7528\u30c6\u30f3\u30d7\u30ec -->\n    <!--\n    <a href=\"\u30ea\u30f3\u30af\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"\u753b\u50cfURL\" alt=\"\u4ee3\u66ff\u30c6\u30ad\u30b9\u30c8\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">\u25ef\u25ef\u9662<\/p>\n        <p>\u4f4f\u6240<\/p>\n        <p>\u55b6\u696d\u6642\u9593<\/p>\n      <\/div>\n    <\/a>\n    -->\n  <\/div>\n<\/section>\n<!-- \u25b2\u25b2 \u3053\u3053\u307e\u3067\u5171\u901a\u30d1\u30fc\u30c4 \u25b2\u25b2 -->\n\n\n\n<!-- \u25bc\u25bc \u533b\u5e2b\u76e3\u4fee\u30d6\u30ed\u30c3\u30af v4 \u25bc\u25bc -->\n<section class=\"ssc-audit-bg\">\n  <div class=\"ssc-audit-box\">\n\n    <h2 class=\"ssc-audit-title\">About the physician supervision of this site<\/h2>\n\n    <p>This site is operated under the supervision of a Smart Skin Clinic supervising physician.<\/p>\n\n    <p>This page was produced in accordance with the Medical Advertising Guidelines\n      <a href=\"https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/iryou\/kokokukisei\/index.html\" target=\"_blank\" rel=\"noopener\">Medical Advertising Guidelines<\/a> revised and enforced in June 2018, under which we produce and provide this information.<\/p>\n\n    <ul>\n      <li>Scope of supervision: treatment descriptions, risks and side effects, price display<\/li>\n      <li>Last Reviewed: August 1, 2026<\/li>\n    <\/ul>\n\n    <small>*Treatment effects vary from person to person. Please be sure to consult a physician regarding side effects and risks.<\/small>\n\n  <\/div>\n<\/section>\n<!-- \u25b2\u25b2 \u533b\u5e2b\u76e3\u4fee\u30d6\u30ed\u30c3\u30af v4 \u25b2\u25b2 -->","protected":false},"excerpt":{"rendered":"<p>\u300cPRP\u6ce8\u5c04\u304c\u304a\u3067\u3053\u306e\u30b7\u30ef\u306b\u52b9\u679c\u7684\u3063\u3066\u805e\u3044\u305f\u3051\u3069\u3001\u672c\u5f53\u306b\u52b9\u679c\u304c\u3042\u308b\u306e\uff1f\u5b89\u5168\u6027\u306f\u3069\u3046\u306a\u3093\u3060\u308d\u3046\uff1f\u300d \u300cPRP\u306bF [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":14,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"swell_btn_cv_data":"","footnotes":""},"class_list":["post-6489","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/6489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/comments?post=6489"}],"version-history":[{"count":20,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/6489\/revisions"}],"predecessor-version":[{"id":16927,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/6489\/revisions\/16927"}],"up":[{"embeddable":true,"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/pages\/14"}],"wp:attachment":[{"href":"https:\/\/smartskin-clinic.com\/en\/wp-json\/wp\/v2\/media?parent=6489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}