{"id":3462,"date":"2024-02-18T00:41:52","date_gmt":"2024-02-17T15:41:52","guid":{"rendered":"https:\/\/smartskin-clinic.com\/?page_id=3462"},"modified":"2026-10-07T11:22:17","modified_gmt":"2026-10-07T02:22:17","slug":"semprotan-hidung-exosome","status":"publish","type":"page","link":"https:\/\/smartskin-clinic.com\/id\/menu\/exosome-nasalspray\/","title":{"rendered":"Terapi tetes hidung eksosom"},"content":{"rendered":"<div class=\"swell-block-fullWide pc-py-0 sp-py-0 alignfull\" style=\"background-color:#f7f7f7\"><div class=\"swell-block-fullWide__inner\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"614\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/11\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u85ac\u30a2\u30a4\u30ad\u30e3\u30c3\u30c1-6747dab683b0b-614x1024.jpg\" alt=\"Obat tetes hidung eksosom Penangkap Mata.\" class=\"wp-image-6730\" style=\"width:480px\" srcset=\"\" sizes=\"auto, (max-width: 614px) 100vw, 614px\" data-srcset=\"\" \/><\/figure>\n<\/div><\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><span class=\"swl-fz u-fz-s\"><span style=\"color:#777777\" class=\"swl-inline-color\">*Harga perdana berlaku untuk Anda yang pertama kali membeli produk ini di klinik kami.<\/span><\/span><\/p>\n\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/id\/reservasi-semprotan-hidung-exosome\/\" class=\"swell-block-button__link\"><span>Reservasi online atau pemesanan konsultasi gratis di sini<\/span><\/a><\/div>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<p class=\"wp-block-paragraph\"><strong>\"Saya tahu infus IV eksosom, tetapi apa itu semprot hidung? Apa bedanya?\"<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\"Saya ingin menjalani semprot hidung eksosom, tetapi masih bingung memilih tempatnya\"<\/strong><\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Apakah Anda memiliki pertanyaan atau kekhawatiran seperti ini?<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Eksosom merupakan perawatan yang terkenal sebagai terapi anti-penuaan, dan terdapat berbagai metode pemberiannya, seperti infus atau suntikan ke wajah. Di antara metode-metode tersebut, mengenai metode \"instilasi hidung\" yang diberikan melalui hidung, <strong><span class=\"swl-marker mark_blue\">Klinik Dermatologi Estetika yang merupakan Fasilitas Terakreditasi Rencana Penyediaan Terapi Regeneratif dari Kementerian Kesehatan, Tenaga Kerja, dan Kesejahteraan Jepang <\/span><\/strong> akan memberikan penjelasan yang mudah dipahami dari sudut pandang profesional. <br><span class=\"swl-fz u-fz-s\">(*Nomor Sertifikasi Rencana Penyediaan Terapi Regeneratif Tipe II dan Tipe III: NA8230001)<\/span><br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">*Bagi Anda yang sedang membandingkan klinik dan penasaran dengan biayanya, melompat dari daftar isi di bawah ini dapat menghemat waktu Anda.<\/p>\n\n\n\n<!-- ======================================\n     \u76e3\u4fee\u8005\u60c5\u5831 \u2013 Smart Skin Clinic\n     Brand Colors: #ffffff #000000 #f5f5f5 #a3e3fc\n====================================== -->\n<section class=\"ssc-supervisor\">\n\n  <!-- \u76e3\u4fee\u8005\u60c5\u5831\u30bf\u30a4\u30c8\u30eb -->\n  <div class=\"ssc-supervisor-title-wrapper\">\n    <span class=\"ssc-supervisor-title\">Informasi Penyelia<\/span>\n  <\/div>\n\n  <div class=\"ssc-supervisor-inner\">\n\n    <!-- \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f -->\n    <div class=\"ssc-supervisor-photo\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg\" alt=\"Kota Ishii, Direktur Utama Grup Klinik Smart Skin\" loading=\"lazy\" \/>\n    <\/div>\n\n    <!-- \u30c6\u30ad\u30b9\u30c8\u60c5\u5831 -->\n    <div class=\"ssc-supervisor-text\">\n\n      <p class=\"ssc-supervisor-role\">Direktur Utama Smart Skin Clinic Group<\/p>\n      <p class=\"ssc-supervisor-name translation-block\"><ruby>Ishii<rt>Ishii<\/rt><\/ruby> <ruby>Kota<rt>Kota<\/rt><\/ruby><\/p>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Riwayat<\/h4>\n        <p>Lulus dari Fakultas Kedokteran Universitas Juntendo<\/p>\n        <p>Bekerja di Rumah Sakit Universitas Kedokteran Wanita Tokyo dan fasilitas terkait<\/p>\n        <p>Bekerja di klinik kecantikan ternama di Tokyo<\/p>\n      <\/div>\n\n      <div class=\"ssc-supervisor-block\">\n        <h4>Afiliasi \/ Kualifikasi<\/h4>\n        <p>Dokter Spesialis Bersertifikat Japan Surgical Society<\/p>\n        <p>Dokter Spesialis Bersertifikat Japanese Society of Anti-Aging Medicine<\/p>\n      <\/div>\n\n    <\/div><!-- \/.text -->\n  <\/div><!-- \/.inner -->\n<\/section>\n\n<style>\n\/* =========================================================\n  Smart Skin Clinic \u2013 Supervisor Component (Monotone + Water)\n========================================================= *\/\n\n\/* \u25c7 \u30d1\u30ec\u30c3\u30c8 *\/\n:root{\n  --ssc-black:#000000;\n  --ssc-white:#ffffff;\n  --ssc-gray:#f5f5f5;\n  --ssc-water:#a3e3fc;   \/* \u30a2\u30af\u30bb\u30f3\u30c8\u6c34\u8272 *\/\n}\n\n\/* \u30bb\u30af\u30b7\u30e7\u30f3 *\/\n.ssc-supervisor{\n  background:var(--ssc-gray);\n  padding:40px 5%;\n  border:1px solid #e0e0e0;\n  border-radius:8px;\n  margin:40px 0;\n  color:var(--ssc-black);\n  font-family:\"Noto Sans JP\",\"Hiragino Sans\",\"Helvetica Neue\",Arial,sans-serif;\n}\n\n\/* \u30bf\u30a4\u30c8\u30eb *\/\n.ssc-supervisor-title-wrapper {\n  font-size: 1.5rem;\n  font-weight: 700;\n  margin: 0 0 24px;\n  display: flex;\n  align-items: flex-end;\n  gap: 8px;\n  color: var(--ssc-black);\n}\n\n.ssc-supervisor-title {\n  font-size: 1.5rem;\n  font-weight: 700;\n  color: var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30ec\u30a4\u30a2\u30a6\u30c8 *\/\n.ssc-supervisor-inner{\n  display:flex;\n  gap:28px;\n  flex-wrap:wrap;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8 *\/\n.ssc-supervisor-text{\n  flex:1 1 260px;\n  min-width:260px;\n}\n.ssc-supervisor-role{\n  font-size:0.9rem;\n  color:var(--ssc-black);  \/* \u9ed2\u6587\u5b57\u306b\u4fee\u6b63 *\/\n  margin:0 0 4px;\n}\n.ssc-supervisor-name{\n  font-size:1.25rem;\n  font-weight:700;\n  margin:0 0 16px;\n  background-color:transparent;  \/* \u80cc\u666f\u306e\u8272\u3092\u900f\u660e\u306b\u8a2d\u5b9a *\/\n  color:var(--ssc-black); \/* \u6587\u5b57\u8272\u3092\u9ed2\u306b *\/\n}\n\n\/* \u30d6\u30ed\u30c3\u30af *\/\n.ssc-supervisor-block{\n  margin-bottom:18px;\n}\n.ssc-supervisor-block h4{\n  font-size:1rem;\n  font-weight:600;\n  margin:0 0 6px;\n  color:var(--ssc-black);\n  border-left:4px solid var(--ssc-water);\n  padding-left:8px;\n}\n\n\/* \u30c6\u30ad\u30b9\u30c8\u8868\u793a\u306e\u5909\u66f4\uff08\u7b87\u6761\u66f8\u304d\u306f\u4f7f\u7528\u305b\u305a\u3001\u30b7\u30f3\u30d7\u30eb\u306b\u8868\u793a\uff09 *\/\n.ssc-supervisor-block p{\n  font-size:1rem;\n  margin: 0 0 10px;\n  color: var(--ssc-black);\n  line-height: 1.6;\n}\n\n\/* \u76e3\u4fee\u533b\u5e2b \u9854\u5199\u771f *\/\n.ssc-supervisor-photo{\n  flex:0 0 190px;\n  max-width:190px;\n}\n.ssc-supervisor-photo img{\n  width:100%;\n  height:auto;\n  display:block;\n  border-radius:8px;\n}\n\n\/* \u30b9\u30de\u30db *\/\n@media(max-width:600px){\n  .ssc-supervisor-inner{\n    flex-direction:column;\n    gap:20px;\n  }\n  .ssc-supervisor-photo{\n    flex:0 0 auto;\n    max-width:150px;\n    margin:0 auto;\n  }\n}\n<\/style>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Apa itu obat tetes hidung eksosom?<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Ini adalah prosedur yang \"memberikan eksosom melalui hidung\", di mana eksosom memiliki efek anti-penuaan.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Untuk metode pemberian eksosom, infus IV maupun Dermapen mungkin lebih dikenal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Dengan pemberian melalui hidung, eksosom dapat dihantarkan ke otak, sehingga efek seperti pencegahan demensia, peningkatan konsentrasi, dan perbaikan kelelahan otak dapat diharapkan.<\/p>\n\n\n\n<div style=\"height:54px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Apa itu eksosom?<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"650\" height=\"500\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/HP\u7528-1.jpg\" alt=\"eksosom\" class=\"wp-image-3497\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/HP\u7528-1.jpg 650w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/HP\u7528-1-300x231.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/HP\u7528-1-16x12.jpg 16w\" sizes=\"auto, (max-width: 650px) 100vw, 650px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Eksosom adalah zat yang secara alami sudah ada di dalam tubuh. Secara medis, eksosom merupakan vesikel sel kecil yang terbungkus membran lipid dua lapis, disekresikan secara aktif oleh berbagai sel, dan berperan penting dalam komunikasi antarsel.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Melalui perannya dalam komunikasi antarsel ini, eksosom memberikan beragam efek seperti anti-apoptosis, anti-inflamasi, neurogenik, dan angiogenik. Sebagai hasil dari efek-efek tersebut, eksosom memberikan apa yang disebut efek anti-penuaan.<\/p>\n\n\n\n<div style=\"height:37px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Variasi metode pemberian eksosom<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Metode pemberian eksosom secara garis besar dapat dibagi menjadi dua pola: pemberian sistemik dan pemberian lokal.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pemberian sistemik<\/h3>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list is-style-num_circle\">\n<li>Infus IV<\/li>\n\n\n\n<li>injeksi<\/li>\n\n\n\n<li>Semprot hidung<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Detail pemberian melalui infus IV dapat dilihat di sini.<\/p>\n\n\n<div class=\"swell-block-postLink\">\t\t\t<div class=\"p-blogCard -external -noimg\" data-type=\"type3\" data-onclick=\"clickLink\">\n\t\t\t\t<div class=\"p-blogCard__inner\">\n\t\t\t\t\t<span class=\"p-blogCard__caption\">[Resmi] Smart Skin Clinic&#8230;<\/span>\n\t\t\t\t\t\t\t\t\t\t<div class=\"p-blogCard__body\">\n\t\t\t\t\t\t<a class=\"p-blogCard__title\" href=\"https:\/\/smartskin-clinic.com\/id\/menu\/infus-injeksi\/infus-eksosom\/\" target=\"_blank\" rel=\"noopener noreferrer\">Apa Itu Infus Eksosom? | Penjelasan Dokter Mengenai Manfaat, Biaya, dan Frekuensi | [Resmi] Smart Skin Clinic Group<\/a>\n\t\t\t\t\t\t<span class=\"p-blogCard__excerpt\">Infus eksosom adalah infus perawatan anti-penuaan yang membantu menyeimbangkan kondisi tubuh secara keseluruhan. Smart Skin Clinic menggunakan formulasi dengan kemurnian tinggi, dan dokter akan memberikan panduan yang disesuaikan dengan kebutuhan masing-masing pasien. Tokyo (Jimbocho, \u2026<\/span>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\n<div style=\"height:38px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Pemberian lokal<\/h3>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list is-style-num_circle\">\n<li>injeksi Water Light<\/li>\n\n\n\n<li>Dermapen<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Detail pemberian dengan Dermapen dapat dilihat di sini.<\/p>\n\n\n<div class=\"swell-block-postLink\">\t\t\t<div class=\"p-blogCard -external -noimg\" data-type=\"type3\" data-onclick=\"clickLink\">\n\t\t\t\t<div class=\"p-blogCard__inner\">\n\t\t\t\t\t<span class=\"p-blogCard__caption\">[Resmi] Smart Skin Clinic&#8230;<\/span>\n\t\t\t\t\t\t\t\t\t\t<div class=\"p-blogCard__body\">\n\t\t\t\t\t\t<a class=\"p-blogCard__title\" href=\"https:\/\/smartskin-clinic.com\/id\/eksosom-dermapen\/\" target=\"_blank\" rel=\"noopener noreferrer\">Apa Itu Dermapen 4 \u00d7 Eksosom? | Penjelasan Dokter tentang Efek, Biaya, dan Waktu Pemulihan | [Resmi] Smart Skin Clinic\u2026<\/a>\n\t\t\t\t\t\t<span class=\"p-blogCard__excerpt\">Dermapen + cairan pengantar eksosom efektif untuk perbaikan kualitas kulit dan perbaikan pori-pori. Downtime pun berkurang berkat cairan pengantar eksosom. Smart Skin Cli yang mengadopsi sediaan eksosom resmi Dermapen&#8230;<\/span>\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Efek<\/h2>\n\n\n\n<div class=\"wp-block-group has-border -border01\"><div class=\"wp-block-group__inner-container\">\n<ul class=\"wp-block-list is-style-check_list\">\n<li>Pencegahan demensia<\/li>\n\n\n\n<li>Perbaikan kelelahan otak<\/li>\n\n\n\n<li>Perbaikan insomnia<\/li>\n\n\n\n<li>Peningkatan konsentrasi<\/li>\n\n\n\n<li>Rinitis alergi<\/li>\n\n\n\n<li>Perbaikan gejala sisa COVID<\/li>\n<\/ul>\n\n\n\n<div style=\"height:13px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">*Efek yang dapat diharapkan<br>*Ada perbedaan antarindividu<\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Untuk menghantarkan zat tertentu ke otak, zat tersebut perlu melewati penghalang yang disebut BBB.<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl2\"><div class=\"cap_box_ttl\"><span>Apa itu BBB?<\/span><\/div><div class=\"cap_box_content\">\n<p class=\"wp-block-paragraph\">BBB adalah istilah medis, singkatan dari Blood Brain Barrier, yang dalam bahasa Jepang disebut penghalang darah-otak.<\/p>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Untuk mengatasi rintangan dan penghalang ini, pemberian melalui hidung mulai mendapat perhatian sebagai jalur non-invasif (tanpa kerusakan) yang efektif untuk menghantarkan obat ke sistem saraf pusat (otak).<br><br>Banyak penelitian telah mengonfirmasi bahwa pemberian melalui hidung (intranasal) dapat melewati BBB dan menghantarkan zat bermolekul kecil maupun protein bermolekul besar ke sistem saraf pusat (otak).<\/p>\n\n\n\n<div class=\"swell-block-capbox cap_box is-style-onborder_ttl2\"><div class=\"cap_box_ttl\"><span>Referensi<\/span><\/div><div class=\"cap_box_content\">\n<ul class=\"wp-block-list is-style-note_list\">\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0014480015000192?via%3Dihub\">Li YH, Feng L, Zhang GX, Ma CG. Intranasal delivery of stem cells as therapy for central nervous system disease. Exp Mol Pathol. 2015;98(2):145\u201351.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0169409X11002997?via%3Dihub\">Banks WA. Drug delivery to the brain in Alzheimer's disease: consideration of the blood-brain barrier. Adv Drug Deliv Rev. 2012;64(7):629\u201339.<\/a><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Pemberian melalui hidung memiliki keunggulan non-invasif dan kepraktisan yang tinggi. Pemberian intranasal memudahkan berbagai jenis molekul obat maupun sel punca untuk melewati BBB dan mencapai sistem saraf pusat, sehingga menawarkan metode yang non-invasif dan efektif untuk terapi sel punca pada penyakit sistem saraf pusat.<\/p>\n<cite><a href=\"https:\/\/stemcellres.biomedcentral.com\/articles\/10.1186\/s13287-021-02274-0\">Yu-Ting Zhang, et al. Advances in intranasal application of stem cells in the treatment of central nervous system diseases. Stem Cell Research &amp; Therapy volume 12, Article number: 210 (2021).<\/a><\/cite><\/blockquote>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"swell-block-capbox cap_box\"><div class=\"cap_box_ttl\"><span>Ilustrasi pemberian eksosom melalui semprot hidung dalam penelitian klinis pada tikus<\/span><\/div><div class=\"cap_box_content\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"829\" height=\"586\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u70b9\u9f3b\u306b\u3088\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6295\u4e0e.jpeg\" alt=\"Pemberian eksosom melalui tetes hidung\" class=\"wp-image-3467\" style=\"width:600px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u70b9\u9f3b\u306b\u3088\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6295\u4e0e.jpeg 829w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u70b9\u9f3b\u306b\u3088\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6295\u4e0e-300x212.jpeg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u70b9\u9f3b\u306b\u3088\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6295\u4e0e-768x543.jpeg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u70b9\u9f3b\u306b\u3088\u308b\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u6295\u4e0e-18x12.jpeg 18w\" sizes=\"auto, (max-width: 829px) 100vw, 829px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">(Sumber)<a href=\"https:\/\/journals.lww.com\/nrronline\/fulltext\/2024\/06000\/intranasal_administration_of_stem_cell_derived.26.aspx\">Gotoh, Shuho, et al. Intranasal administration of stem cell-derived exosomes for central nervous system diseases. Neural Regeneration Research 19(6):p 1249-1255, June 2024.<\/a><\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:31px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Efek terapi semprot hidung pada pasien demensia tipe Alzheimer<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Tersedia data mengenai penerapan terapi semprot hidung pada pasien demensia tipe Alzheimer.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"909\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u3078\u306e\u52b9\u679c.png\" alt=\"Efek tetes hidung eksosom pada penyakit Alzheimer.\" class=\"wp-image-3469\" style=\"width:600px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u3078\u306e\u52b9\u679c.png 1000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u3078\u306e\u52b9\u679c-300x273.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u3078\u306e\u52b9\u679c-768x698.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u70b9\u9f3b\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u3078\u306e\u52b9\u679c-13x12.png 13w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n<\/div>\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Dengan menggunakan eksosom, terlihat efek perbaikan yang menonjol pada penyakit yang sulit disembuhkan seperti demensia tipe Alzheimer, infark serebral, dermatitis atopik, artritis reumatoid, dan alergi serbuk sari.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tanpa memerlukan operasi \"transplantasi\" yang mahal,<strong>perawatan dapat dilakukan hanya dengan infus, pengolesan sebagai obat luar, atau inhalasi melalui hidung.<\/strong>\u3000\u3000\u3000<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Teknologi inovatif ini telah menjadi subjek penelitian klinis bersama berskala besar dengan Universitas Bergen, Norwegia, sejak tahun 2019.<\/p>\n<cite>Minoru Ueda, \"Kedokteran Regeneratif yang Menakjubkan \u2014 Apa Itu Kultur Supernatan\"<\/cite><\/blockquote>\n\n\n\n<div style=\"height:53px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Kelebihan\/kekurangan semprot hidung<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Kelebihan<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Dengan pemberian melalui hidung, eksosom dapat mencapai otak.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pada pembuluh darah menuju otak terdapat penghalang bernama BBB (penghalang darah-otak), yang membuat hanya komponen tertentu yang dapat masuk ke otak. Karena itu, pada pemberian melalui infus dan sejenisnya, eksosom tidak dapat dihantarkan ke otak secara efisien.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sementara itu, seperti disebutkan sebelumnya, pemberian eksosom melalui hidung (pemberian intranasal) memungkinkan eksosom mencapai otak secara langsung sambil melewati penghalang darah-otak.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Kekurangan<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Untuk kekurangannya, mungkin ada faktor \"membutuhkan biaya\".<\/p>\n\n\n\n<div style=\"height:53px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Risiko &amp; efek samping<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Pada dasarnya sama dengan infus IV eksosom. Berbeda dengan infus, tidak ada jarum yang ditusukkan, sehingga tidak ada efek samping akibat penusukan jarum.<\/p>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Upaya keselamatan\uff5cKepatuhan terhadap Panduan Masyarakat Kedokteran Regeneratif<\/h2>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Perawatan infus eksosom di klinik kami dilaksanakan <strong><span class=\"swl-marker mark_blue\">sesuai dengan \"Panduan mengenai Aplikasi Klinis Vesikel Ekstraseluler dan Sejenisnya (Edisi Pertama)\" yang diterbitkan oleh Japanese Society for Regenerative Medicine pada 30 April 2024.<\/span><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Panduan ini menjadi pedoman penting untuk memastikan keamanan dan efektivitas terapi eksosom, dan klinik kami menjalankan <strong><span class=\"swl-marker mark_blue\">pengelolaan mutu yang ketat serta upaya penjaminan keamanan berdasarkan panduan tersebut<\/span><\/strong>.<\/p>\n\n\n\n<div style=\"height:34px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Langkah-langkah konkret klinik kami untuk memastikan keamanan<\/h3>\n\n\n\n<ol class=\"wp-block-list is-style-num_circle\">\n<li><strong>Pelaksanaan pembuatan profil risiko<\/strong>\n<ul class=\"wp-block-list\">\n<li>Kami mengidentifikasi potensi risiko yang terkait dengan perawatan dan mengambil langkah penanganan yang tepat.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Proses persiapan dan kontrol mutu yang ketat<\/strong>\n<ul class=\"wp-block-list\">\n<li>Kami menjalankan proses produksi dan pemeriksaan mutu berdasarkan temuan ilmiah terbaru.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Pelaksanaan verifikasi efektivitas yang tepat<\/strong>\n<ul class=\"wp-block-list\">\n<li>Kami terus mengevaluasi efektivitas perawatan untuk memberikan perawatan yang paling sesuai bagi Anda.<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<div style=\"height:23px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Kami mengutamakan keselamatan Anda dan berkomitmen memberikan perawatan berdasarkan temuan ilmiah terbaru.<\/p>\n\n\n\n<div style=\"height:55px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Cara penggunaan semprot hidung (petunjuk pemakaian)<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"614\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2-614x1024.jpg\" alt=\"Cara membuat sediaan cair\" class=\"wp-image-3478\" style=\"width:400px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2-614x1024.jpg 614w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2-180x300.jpg 180w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2-768x1280.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2-7x12.jpg 7w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/1-2.jpg 780w\" sizes=\"auto, (max-width: 614px) 100vw, 614px\" \/><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"614\" height=\"1024\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2-614x1024.jpg\" alt=\"Cara menyemprot\" class=\"wp-image-3479\" style=\"width:400px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2-614x1024.jpg 614w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2-180x300.jpg 180w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2-768x1280.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2-7x12.jpg 7w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/2-2.jpg 780w\" sizes=\"auto, (max-width: 614px) 100vw, 614px\" \/><\/figure>\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">Keunggulan terapi semprot hidung eksosom di Smart Skin Clinic<\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0.png\" alt=\"set tetes hidung\" class=\"wp-image-3492\" style=\"width:500px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0.png 1000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0-300x300.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0-150x150.png 150w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0-768x768.png 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_exosome_2_0-12x12.png 12w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\">Menggunakan eksosom yang berasal dari tali pusat<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Terdapat tiga jenis utama eksosom, yaitu \u2460 berasal dari tali pusat, \u2461 berasal dari lemak, dan \u2462 berasal dari pulpa gigi\/sumsum tulang; Smart Skin Clinic menggunakan eksosom \"\u2460 yang berasal dari tali pusat\".<br><br>Dibandingkan dengan eksosom lainnya, eksosom yang berasal dari tali pusat mengandung lebih dari 14 kali lipat komponen yang memberikan efek, seperti ditunjukkan diagram di bawah ini.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"614\" height=\"495\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0.png\" alt=\"Perbedaan antara eksosom yang berasal dari darah tali pusat dan sumber lainnya Pendahuluan 1).\" class=\"wp-image-1668\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0.png 614w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0-300x242.png 300w\" sizes=\"auto, (max-width: 614px) 100vw, 614px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Kami juga akan memperkenalkan dua hal terkait \"bahan aktif\" ini, termasuk data konkretnya.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u2460 Kaya akan bahan aktif untuk kulit<\/h4>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Yang pertama adalah data mengenai bahan aktif untuk \"kulit\".<br><br>Eksosom memiliki beragam efek anti-penuaan, dan salah satunya adalah efek terhadap \"kulit\". Seperti ditunjukkan diagram di bawah ini, eksosom yang berasal dari tali pusat mengandung bahan aktif untuk kulit lebih banyak dibanding eksosom lainnya.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"444\" height=\"487\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u2461.png\" alt=\"Perbedaan antara eksosom yang berasal dari darah tali pusat dan sumber eksosom lainnya (2).\" class=\"wp-image-1669\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u2461.png 444w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u2461-274x300.png 274w\" sizes=\"auto, (max-width: 444px) 100vw, 444px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:33px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">\u2461 Kaya akan protein peremajaan \"GDF-11\"<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Yang kedua adalah data mengenai komponen yang berperan dalam \"peremajaan\".<br><br>Terdapat komponen bernama GDF-11 yang berperan dalam peremajaan, dan eksosom yang berasal dari tali pusat mengandungnya secara melimpah seperti ditunjukkan data berikut.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"569\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/GDF-1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0.jpg\" alt=\"Eksosom yang berasal dari darah tali pusat dengan aktivitas GDF-1 yang tinggi.\" class=\"wp-image-1672\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/GDF-1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0.jpg 1000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/GDF-1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0-300x171.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2023\/09\/GDF-1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u81cd\u5e2f\u8840\u7531\u6765\u30a8\u30af\u30bd\u30bd\u30fc\u30e0-768x437.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">&#8221;Dedikasi&#8220; terhadap harga dan kualitas<\/h3>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"1000\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0.jpg\" alt=\"kotak mimisan\" class=\"wp-image-3490\" style=\"width:400px\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0.jpg 1000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0-300x300.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0-150x150.jpg 150w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0-768x768.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/02\/PS_nasal_1_0-12x12.jpg 12w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">Klinik kami memiliki dedikasi terhadap harga dan kualitas. Untuk mewujudkan dedikasi tersebut, kami menjalankan berbagai upaya. Kami menerapkan berbagai efisiensi biaya (misalnya: tidak membuat interior mewah, meniadakan resepsionis untuk mengurangi biaya tenaga kerja) dan lain-lain.<br><br>Silakan lihat di sini untuk detailnya.<\/p>\n\n\n\n<blockquote class=\"instagram-media\" data-instgrm-permalink=\"https:\/\/www.instagram.com\/p\/C0lhfufycQM\/?utm_source=ig_embed&amp;utm_campaign=loading\" data-instgrm-version=\"14\" style=\" background:#FFF; border:0; border-radius:3px; box-shadow:0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width:540px; min-width:326px; padding:0; width:99.375%; width:-webkit-calc(100% - 2px); width:calc(100% - 2px);\"><div style=\"padding:16px;\"> <a href=\"https:\/\/www.instagram.com\/p\/C0lhfufycQM\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" background:#FFFFFF; line-height:0; padding:0 0; text-align:center; text-decoration:none; width:100%;\" target=\"_blank\" rel=\"noopener\"> <div style=\" display: flex; flex-direction: row; align-items: center;\"> <div style=\"background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;\"><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;\"><\/div><\/div><\/div><div style=\"padding: 19% 0;\"><\/div> <div style=\"display:block; height:50px; margin:0 auto 12px; width:50px;\"><svg width=\"50px\" height=\"50px\" viewbox=\"0 0 60 60\" version=\"1.1\" xmlns=\"https:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"https:\/\/www.w3.org\/1999\/xlink\"><g stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\"><g transform=\"translate(-511.000000, -20.000000)\" fill=\"#000000\"><g><path d=\"M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631\"><\/path><\/g><\/g><\/g><\/svg><\/div><div style=\"padding-top: 8px;\"> <div style=\" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;\">Lihat postingan ini di Instagram<\/div><\/div><div style=\"padding: 12.5% 0;\"><\/div> <div style=\"display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;\"><div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);\"><\/div> <div style=\"background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;\"><\/div> <div style=\"background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);\"><\/div><\/div><div style=\"margin-left: 8px;\"> <div style=\" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;\"><\/div> <div style=\" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg)\"><\/div><\/div><div style=\"margin-left: auto;\"> <div style=\" width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);\"><\/div> <div style=\" background-color: #F4F4F4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);\"><\/div> <div style=\" width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);\"><\/div><\/div><\/div> <div style=\"display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;\"> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;\"><\/div> <div style=\" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;\"><\/div><\/div><\/a><p style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; line-height:17px; margin-bottom:0; margin-top:8px; overflow:hidden; padding:8px 0 7px; text-align:center; text-overflow:ellipsis; white-space:nowrap;\"><a href=\"https:\/\/www.instagram.com\/p\/C0lhfufycQM\/?utm_source=ig_embed&amp;utm_campaign=loading\" style=\" color:#c9c8cd; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:normal; line-height:17px; text-decoration:none;\" target=\"_blank\" rel=\"noopener\">Kiriman yang dibagikan oleh Smart Skin Clinic\u3010Dermatologi Estetika\u3011Jimbocho Juvelook&amp;Profhilo&amp;Sunekos (@smartskin_clinic)<\/a><\/p><\/div><\/blockquote> <script async src=\"\/\/www.instagram.com\/embed.js\"><\/script>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Sesuai dengan MISEV2018 \"Minimal Information for Studies of Extracellular Vesicles (MISEV) edisi 2018\"<\/h3>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Pada eksosom, metode ekstraksi, ukuran eksosom, metode penyimpanan, serta bentuknya, dan sebagainya, dapat bervariasi. <br><br>Oleh karena itu, International Society for Extracellular Vesicles (ISEV) telah menetapkan pedoman untuk standarisasi protokol eksosom. <br><br>Pedoman yang diusulkan oleh ISEV adalah \"Minimal Information for Studies of Extracellular Vesicles (MISEV) Edisi 2018\". <br><br><strong><span class=\"swl-marker mark_blue\">Di rumah sakit kami, kami mematuhi MISEV 2018 ini dan melakukan ekstraksi serta pemurnian di fasilitas pengolahan kultur sel, dan hasilnya digunakan di rumah sakit kami<\/span><\/strong>.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"760\" height=\"586\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/09\/misev2018.png\" alt=\"\" class=\"wp-image-5848\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/09\/misev2018.png 760w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/09\/misev2018-300x231.png 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2024\/09\/misev2018-16x12.png 16w\" sizes=\"auto, (max-width: 760px) 100vw, 760px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:12px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/id\/reservasi-semprotan-hidung-exosome\/\" class=\"swell-block-button__link\"><span>Reservasi online atau pemesanan konsultasi gratis di sini<\/span><\/a><\/div>\n\n\n\n<div style=\"height:72px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Biaya<\/h2>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"10708\">\n<figure class=\"wp-block-table is-all-centered\"><table><thead style=\"--thead-color--bg:var(--color_gray);--thead-color--txt:var(--swl-text_color--black)\"><tr><th>1 botol 5cc [persediaan 1 minggu]<\/th><th><\/th><\/tr><\/thead><tbody><tr><td>Harga kunjungan pertama<\/td><td>29,440 yen<\/td><\/tr><tr><td>1 botol<\/td><td>36,800 yen<\/td><\/tr><tr><td>2 botol (persediaan 2 minggu)<\/td><td>71,600 yen<br><span style=\"color:#929292\" class=\"swl-inline-color\">(per botol 35,800 yen<\/span>)<\/td><\/tr><tr><td>4 botol (persediaan 1 bulan)<\/td><td class=\"translation-block\">131.200 yen<br><span style=\"color:#929292\" class=\"swl-inline-color\">(1 botol <\/span> <span class=\"swl-inline-color has-swl-main-color\">32.800 yen <\/span>)<\/td><\/tr><tr><td>12 botol (persediaan 3 bulan)<\/td><td class=\"translation-block\">345.600 yen<br><span style=\"color:#929292\" class=\"swl-inline-color\">(1 botol<\/span> <span class=\"swl-inline-color has-swl-main-color\">28.800 yen<\/span>)<\/td><\/tr><\/tbody><\/table><figcaption class=\"wp-element-caption\">*Bila digunakan sesuai anjuran, satu botol memiliki kapasitas untuk sekitar satu minggu.<\/figcaption><\/figure>\n<\/div>\n\n\n<div class=\"swell-block-button blue_ -size-l is-style-btn_solid\"><a href=\"https:\/\/smartskin-clinic.com\/id\/reservasi-semprotan-hidung-exosome\/\" class=\"swell-block-button__link\"><span>Reservasi online atau pemesanan konsultasi gratis di sini<\/span><\/a><\/div>\n\n\n<div class=\"p-blogParts post_content\" data-partsid=\"14253\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"650\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA.jpg\" alt=\"\" class=\"wp-image-18918\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA.jpg 2000w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-300x98.jpg 300w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-768x250.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-1536x499.jpg 1536w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/10\/\uff06DR.\u30d0\u30ca\u30fcA-18x6.jpg 18w\" sizes=\"auto, (max-width: 2000px) 100vw, 2000px\" \/><\/figure>\n<\/div>\n\n\n<div style=\"height:113px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n\n<div class=\"wp-block-group ssc-eeat\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\n<h2 class=\"wp-block-heading\">Dokter yang mengawasi halaman ini<\/h2>\n\n\n\n<div class=\"wp-block-media-text profile is-stacked-on-mobile\" style=\"grid-template-columns:28% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"1920\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg\" alt=\"Kota Ishii, Direktur Utama Smart Skin Clinic\" class=\"wp-image-12584 size-full\" srcset=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f.jpg 1280w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-200x300.jpg 200w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-768x1152.jpg 768w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-1024x1536.jpg 1024w, https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/03\/\u77f3\u4e95\u7d71\u62ec\u9662\u9577\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb\u5199\u771f-8x12.jpg 8w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"u-mb-0 wp-block-paragraph\"><span class=\"swl-fz u-fz-s\"><strong>Smart Skin Clinic Direktur Umum \/ Dokter<\/strong><\/span><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span class=\"swl-fz u-fz-l\">Kota Ishii<\/span><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kami mengoordinasikan kebijakan perawatan yang disesuaikan dengan kondisi kulit tiap-tiap pasien di seluruh grup. Isi halaman ini disusun berdasarkan kebijakan perawatan klinik kami.<\/p>\n\n\n\n<div class=\"swell-block-button is-style-btn_normal\"><a href=\"https:\/\/smartskin-clinic.com\/id\/konsep\/\" class=\"swell-block-button__link\"><span>Lihat pandangan dokter dan klinik<\/span><\/a><\/div>\n<\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Wawancara Direktur Kota Ishii<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Kota Ishii, Direktur Umum kami, akan menyampaikan filosofi kami terhadap pelayanan medis di klinik.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Sejumlah pelanggan tetap untuk suntikan pertumbuhan kulit. \u2049\ufe0f Wawancara eksklusif dengan direktur umum yang tampan dari sebuah klinik populer. \ud83e\uddd1\u200d\u2695\ufe0f\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/u6cP6jPmfwU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n<\/div><\/div>\n\n\n\n<!-- \u25bc\u25bc Clinic List \u5171\u901a\u30d1\u30fc\u30c4 \u25bc\u25bc -->\n<section>\n  <!-- \u30bf\u30a4\u30c8\u30eb -->\n  <div class=\"ssc-shoplist-title\">\n    <small>CLINIC LIST<\/small>\n    <h2>Daftar Klinik<\/h2>\n  <\/div>\n  <!-- \u30ab\u30fc\u30c9\u4e00\u89a7 -->\n  <div class=\"ssc-shoplist-grid\">\n    <!-- \u795e\u4fdd\u753a\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/id\/klinik\/jimbocho\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/06\/smart-skin-clinic-jimbocho-reception-waiting-area-.webp\" alt=\"Klinik Kulit Cerdas Klinik Jimbocho Ruang resepsionis dan ruang tunggu Tampilan keseluruhan\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Klinik Jimbocho<\/p>\n        <p>\u3012101-0054<br>3-16-1 Kanda Nishikicho, Chiyoda-ku, Tokyo, Gedung EX Kanda Nishikicho lantai 8 (resepsi utama), lantai 7<\/p>\n        <p>Jam operasional: Senin\u2013Jumat 11:00-20:00 \/ Sabtu &amp; Minggu 10:00-19:00<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u6a2a\u6d5c\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/id\/klinik\/yokohama\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2025\/06\/smartskin-clinic-yokohama-lobby-overview.webp\" alt=\"Klinik Kulit Cerdas Klinik Yokohama Resepsionis dan ruang tunggu Tampilan umum\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Klinik Yokohama<\/p>\n        <p>\u3012221-0835<br>2-23-2 Tsuruyacho, Kanagawa-ku, Yokohama, Prefektur Kanagawa, Gedung TS Plaza lantai 2<\/p>\n        <p>Jam operasional: 10:00-19:00<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u516b\u4e01\u5800\u9662 -->\n    <a href=\"https:\/\/smartskin-clinic.com\/id\/klinik\/hatchobori\/\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"https:\/\/smartskin-clinic.com\/wp-content\/uploads\/2026\/08\/\u516b\u4e01\u5800\u9662_\u53d7\u4ed8\u5f85\u5408.jpg\" alt=\"Smart Skin Clinic Cabang Hatchobori: Tampilan Umum Resepsionis dan Ruang Tunggu\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">Klinik Hatchobori<\/p>\n        <p>Kode Pos 104-0032<br>Lantai 2, Gedung Tokyo NS, 2-29-4 Hatchobori, Chuo-ku, Tokyo<\/p>\n        <p>Jam buka: 10:00\u201319:00 (tutup pukul 13:00\u201314:00) \/ Hari libur: Senin dan Kamis<\/p>\n      <\/div>\n    <\/a>\n    <!-- \u8ffd\u52a0\u9662\u7528\u30c6\u30f3\u30d7\u30ec -->\n    <!--\n    <a href=\"\u30ea\u30f3\u30af\" class=\"ssc-shopcard\" target=\"_blank\" rel=\"noopener\">\n      <img decoding=\"async\" src=\"\u753b\u50cfURL\" alt=\"\u4ee3\u66ff\u30c6\u30ad\u30b9\u30c8\">\n      <div class=\"ssc-shopcard-inner\">\n        <p class=\"ssc-shopcard__name\">\u25ef\u25ef\u9662<\/p>\n        <p>\u4f4f\u6240<\/p>\n        <p>\u55b6\u696d\u6642\u9593<\/p>\n      <\/div>\n    <\/a>\n    -->\n  <\/div>\n<\/section>\n<!-- \u25b2\u25b2 \u3053\u3053\u307e\u3067\u5171\u901a\u30d1\u30fc\u30c4 \u25b2\u25b2 -->\n\n\n\n<!-- \u25bc\u25bc \u533b\u5e2b\u76e3\u4fee\u30d6\u30ed\u30c3\u30af v4 \u25bc\u25bc -->\n<section class=\"ssc-audit-bg\">\n  <div class=\"ssc-audit-box\">\n\n    <h2 class=\"ssc-audit-title\">Tentang pengawasan medis situs ini<\/h2>\n\n    <p>Situs ini dikelola di bawah pengawasan dokter penyelia Smart Skin Clinic.<\/p>\n\n    <p>Halaman ini disusun dan menyajikan informasi berdasarkan\n      <a href=\"https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/kenkou_iryou\/iryou\/kokokukisei\/index.html\" target=\"_blank\" rel=\"noopener\">Pedoman Periklanan Medis<\/a> yang direvisi dan diberlakukan pada Juni 2018.<\/p>\n\n    <ul>\n      <li>Cakupan pengawasan: penjelasan perawatan, risiko &amp; efek samping, tampilan harga<\/li>\n      <li>Tanggal peninjauan terakhir: 1 Agustus 2026<\/li>\n    <\/ul>\n\n    <small>\u203bEfek perawatan berbeda-beda pada setiap orang. 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