PRPF injection [Improvement of dark circles under the eyes
I saw that PRP injections are effective for dark circles under the eyes, but what about their effectiveness and safety?"
I hear that injections of PRP with added FGF are scary."
I just want to get rid of those dark circles under my eyes."
I want to do something about the dark circles under my eyes, and I am comparing various options, such as dewaxing, fat injections, and the hamula method. But I'm afraid of surgery, so I'm wondering if I can do something with injections..."
Hello. I am a doctor at Smart Skin Clinic, a cosmetic dermatology clinic.
Do you have any of these questions or concerns?
In this article,Ministry of Health, Labour and WelfareThe following is an easy-to-understand explanation from a professional standpoint by a cosmetic dermatology clinic that is a member of the "Aesthetic Dermatology Clinic".
(* Type II and Type III Regenerative Medicine Provisioning Plans Accreditation Number: NA8230001)
*If you would like to know the rates, you can jump to the appropriate section from the table of contents below.
What are PRPF injections?
PRPF injections are,Treatment by injecting a preparation containing FGF (fibroblast growth factor) added to PRP (platelet-rich plasma)It is.
PRP: An ingredient extracted from your own blood and rich in growth factors
FGF: Fibroblast growth factor. An ingredient that strongly promotes skin regeneration.
The combination of the two is said to have a greater effect on the dermis than conventional PRP therapy.
Case study photographs (Before/After)
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
Role of growth factors (growth factors)
Growth factor is a general term for proteins and peptides that promote cell growth, division, and differentiationIt is. It has received particular attention in cosmetic medicine, where it contributes to skin rejuvenation and regeneration.
There is more than one growth factor.
Major growth factors include the following
- EGF (epidermal growth factor): helps skin regeneration
- FGF (Fibroblast Growth Factor): Increases collagen and elastin to plump up the skin
- IGF (insulin-like growth factor): creates new cells and reduces damage caused by aging
These growth factors act to :
Increase collagen: Skin becomes more elastic and resilient.
Repairing cells: Treats damaged skin.
Improves blood circulation: delivers plenty of nutrients and oxygen to the skin
Mechanism of PRPF injections: Why do they work on dark circles?
The main reasons why PRPF injections are effective for dark circles under the eyes areFour mechanismsDepends on the
1. promotion of collagen production
Platelet-derived growth factor (PDGF) and FGF contained in PRP stimulate fibroblasts. As a result, collagen production is promoted, improving skin firmness and elasticity. This improves thinning and sagging skin that causes dark circles.
2. promotion of angiogenesis
Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. Blood circulation is improved and blood stasis, one of the causes of blue dark circles, is eliminated.
3. improvement of pigmentation
Transforming growth factor beta (TGF-β) regulates melanocyte activity. This suppresses excessive melanin production, which causes brown circles.
Tissue Repair and Regeneration
Insulin-like growth factor (IGF) promotes cell proliferation and differentiation. It accelerates repair and regeneration of damaged skin tissue and improves overall skin quality.
The combined action of these mechanisms is what makes it effective for various types of dark circles.
Three features of PRPF injections
1. natural rejuvenation effect
Because autologous ingredients are used, the result is natural. Because it enhances the skin's natural regenerative power, it is not unnatural.
2. personalized treatment
Our clinic will adjust the concentration and amount of PRP injected to meet the skin conditions and goals of each individual client, and will design the injection individually.
3. duration and cost performance
Considering the mechanism of PRPF injections, we can expect medium- to long-term effects because the improvement is achieved by approaching the inside of the skin.
*The duration of the effect varies from person to person.
Effects of PRPF injections on different types of dark circles
1. blue dark circles
Cause:
Poor circulation, thinning of the skin
Effects of PRPF injections:
Improved blood circulation by promoting angiogenesis
Collagen production is promoted to thicken the skin and reduce vascular permeability.
2. brown bear
Cause:
Overproduction of melanin pigment
Effects of PRPF injections:
Regulates melanocyte activity and inhibits melanin production
Promotes cell turnover and expels deposited pigment
3. black bear
Cause:
Shadows due to sagging skin and fat loss
Effects of PRPF injections:
Improves sagging by promoting collagen and elastin production
Tissue regeneration to reduce dimpling
PRPF injections are recommended for
Those who are concerned about dark circles under the eyes in general.
・Fine lines and wrinkles under the eyes are becoming more noticeable.
Those who have sunken under eyes.
Those who are concerned about sagging under the eyes
Those who are concerned about under-eye puffiness but wish to avoid surgery.
Features of PRPF Injection at Smart Skin Clinic
1. clinics that specialize in injectable procedures
Our clinic focuses on injectable procedures and has accumulated knowledge and experience in this area.
Injection techniques to reduce pain
Personalized treatment for each customer
2. expertise in the area of regenerative medicine
Regenerative Medicine Provider approved by the Ministry of Health, Labour and Welfare (obtained a Type 2 Regenerative Medicine Provision Plan No.)
Specialist in the Society of Anti-Aging Medicine
3. providing treatments that combine expertise in injectable and regenerative medicine
Leveraging experience in injection systems and knowledge of regenerative medicine
Personalized treatment plans tailored to the client's condition and wishes
Charge
PRPF Injection Prices in Tokyo
The price of PRPF injections in Tokyo is200,000 to 400,000 yen(as of August 1, 2024). (as of August 1, 2024)
Smart Skin Clinic Fee Schedule
| Once | 208,000 yen |
| Monitor] 1 time | 178,000 yen |
| Price per site for more than 2 sites (face) | 166,400 yen (20%OFF from regular price) |
| Monitor] 2nd site (face) | 136,400 yen |
We are a free clinic and not covered by insurance.
The price is indicated as all-inclusive, including consultation and needle fees.
There is no separate upsell on the day of the event.
Monitoring Requirements
(i)Usage｜We may post the photos on our website, Instagram, etc. with the eye area hidden, or show them to other customers as examples of treatment [please think of them as general case photos].
(2)implementation method｜The difference (between the regular price and the monitor price) will be refunded at the time of the monitor's photo shoot (approximately one month after the treatment).
Comparison with other treatment methods
Comparison with hyaluronic acid injection
PRPF: Autologous ingredients with low allergy risk and long-term skin regeneration effects
Hyaluronic acid: Immediate volumizing effect, but absorbed in 6-12 months. Also, there is a risk of vascular occlusion, and caution should be exercised when injecting near blood vessels, such as under the eyes and between the eyebrows.
2. comparison with laser treatment
PRPF: Deep skin action and long-lasting effects
Laser: mainly superficial effect, multiple treatments required
Comparison with surgical procedures
PRPF: Non-invasive, fast recovery, and natural-looking results
Surgical procedures: dramatic changes possible, but with greater risk and downtime
PRPF injection procedure
- Blood sampling: a small amount of blood is drawn from the patient's arm
- PRP extraction: PRP is extracted using a special centrifuge
- FGF addition: FGF is added to the extracted PRP
- Injection design: Individualized design according to the symptoms you want to resolve
- Injection: A fine needle is used to inject into the skin under the eyes.
The needles used are very thin to minimize pain. In addition, anesthesia cream can be used if necessary.
Precautions and Side Effects
PRPF injections are relatively safe, but may cause temporary side effects, including
Mild swelling and internal bleeding at the injection site
Temporary pain or discomfort
In rare cases, infection or inflammatory reactions may occur, but our strict hygiene and skilled techniques minimize these risks.
FAQ
Q1: Is PRPF injection painful?
A1: Most patients experience only mild discomfort due to the use of an extremely fine needle and anesthetic cream if necessary.
Q2: When will I start seeing results?
A2: Although there are individual differences, most people begin to notice gradual effects after 2 to 4 weeks. The greatest effect is often seen after 3-6 months.
summary
PRPF injections are an effective treatment for dark circles under the eyes. It is safe because it uses autologous ingredients and features natural-looking results. The complex mechanism of this treatment can be used to treat various types of dark circles, and long-term results can be expected.
Smart Skin Clinic offers personalized PRP injections, drawing on its expertise in injection-based procedures and regenerative medicine.