PRPF injection [Improvement of dark circles under the eyes

I saw that PRP injections are effective for dark circles under the eyes, but what about their effectiveness and safety?"

I hear that injections of PRP with added FGF are scary."


I just want to get rid of those dark circles under my eyes."

I want to do something about the dark circles under my eyes, and I am comparing various options, such as dewaxing, fat injections, and the hamula method. But I'm afraid of surgery, so I'm wondering if I can do something with injections..."

Hello. I am a doctor at Smart Skin Clinic, a cosmetic dermatology clinic.

Do you have any of these questions or concerns?

In this article,Ministry of Health, Labour and WelfareThe following is an easy-to-understand explanation from a professional standpoint by a cosmetic dermatology clinic that is a member of the "Aesthetic Dermatology Clinic".
(* Type II and Type III Regenerative Medicine Provisioning Plans Accreditation Number: NA8230001)

*If you would like to know the rates, you can jump to the appropriate section from the table of contents below.

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What are PRPF injections?

PRPF injections are,Treatment by injecting a preparation containing FGF (fibroblast growth factor) added to PRP (platelet-rich plasma)It is.

PRP: An ingredient extracted from your own blood and rich in growth factors
FGF: Fibroblast growth factor. An ingredient that strongly promotes skin regeneration.

The combination of the two is more powerful than conventional PRP therapy.

Case study photographs (Before/After)

Role of growth factors (growth factors)

Growth factor is a general term for proteins and peptides that promote cell growth, division, and differentiationIt is. It has attracted particular attention in the field of cosmetic medicine, where it contributes to skin rejuvenation and regeneration.

There is more than one type of growth factor.

Major growth factors include the following

  1. EGF (epidermal growth factor): helps skin regeneration
  2. FGF (Fibroblast Growth Factor): Increases collagen and elastin to plump up the skin
  3. IGF (insulin-like growth factor): creates new cells and reduces damage caused by aging

These growth factors act to

Increase collagen: Skin becomes more elastic and resilient.
Repairing cells: Treats damaged skin.
Improves blood circulation: delivers plenty of nutrients and oxygen to the skin

Mechanism of PRPF injections: Why do they work on dark circles?

The main reasons why PRPF injections are effective for dark circles under the eyes areFour mechanismsDepends on the

1. promotion of collagen production

Platelet-derived growth factor (PDGF) and FGF contained in PRP stimulate fibroblasts. As a result, collagen production is promoted, improving skin firmness and elasticity. This improves thinning and sagging skin that causes dark circles.

2. promotion of angiogenesis

Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. Blood circulation is improved and blood stasis, one of the causes of blue dark circles, is eliminated.

3. improvement of pigmentation

Transforming growth factor beta (TGF-β) regulates melanocyte activity. This suppresses excessive melanin production, which causes brown circles.

Tissue Repair and Regeneration

Insulin-like growth factor (IGF) promotes cell proliferation and differentiation. It accelerates repair and regeneration of damaged skin tissue and improves overall skin quality.

The combined action of these mechanisms is what makes it effective for various types of dark circles.

Three features of PRPF injections

1. natural rejuvenation effect

Because autologous ingredients are used, the result is natural. Because it enhances the skin's natural regenerative power, it is not unnatural.

2. customized treatment

We will adjust the concentration and injection volume of PRP and perform the injection design according to the skin condition and goals of each individual client.

3. long-term effectiveness and cost performance

Effectiveness.Usually lasts 5 years or moreThe treatment is performed in a single session. It is cost-effective because of the long-lasting effect of a single treatment.

Effects of PRPF injections on different types of dark circles

1. blue dark circles

Cause:
Poor circulation, thinning of the skin

Effects of PRPF injections:
Improved blood circulation by promoting angiogenesis
Collagen production is promoted to thicken the skin and reduce vascular permeability.

2. brown bear

Cause:
Overproduction of melanin pigment

Effects of PRPF injections:
Regulates melanocyte activity and inhibits melanin production
Promotes cell turnover and expels deposited pigment

3. black bear

Cause:
Shadows due to sagging skin and fat loss

Effects of PRPF injections:
Improves sagging by promoting collagen and elastin production
Tissue regeneration to reduce dimpling

PRPF injections are recommended for

Those who are concerned about dark circles under the eyes in general.
・Fine lines and wrinkles under the eyes are becoming more noticeable.
Those who have sunken under eyes.
Those who are concerned about sagging under the eyes
Those who are concerned about under-eye puffiness but wish to avoid surgery.

Features of PRPF Injection at Smart Skin Clinic

1. specialist in injectable procedures

Optimal infusion through extensive experience and advanced technology
Unique injection technique to minimize pain
Personalized and customized treatment for each customer

2. expert in regenerative medicine

Regenerative Medicine Provider approved by the Ministry of Health, Labour and Welfare (obtained a Type 2 Regenerative Medicine Provision Plan No.)
Utilization of the latest findings by board-certified physicians of the Japanese Society of Anti-Aging Medicine

3. superiority in combining expertise in injectable and regenerative medicine

More effective and safer treatment
Optimal treatment plans tailored to the client's condition and wishes.

Charge

PRPF Injection Prices in Tokyo

The price of PRPF injections in Tokyo is200,000 to 400,000 yen(as of August 1, 2024). (as of August 1, 2024)

Smart Skin Clinic Fee Schedule

Once208,000 yen
Monitor] 1 time178,000 yen
Price per site for more than 2 sites (face)166,400 yen
(20%OFF from regular price)
Monitor] 2nd site (face)136,400 yen
All prices include tax.
We are a free clinic and not covered by insurance.

The price is indicated as all-inclusive, including consultation and needle fees.
There is no separate upsell on the day of the event.

Monitoring Requirements

(i)Usage|We may post the photos on our website, Instagram, etc. with the eye area hidden, or show them to other customers as examples of treatment [please think of them as general case photos].
(2)implementation method|The difference (between the regular price and the monitor price) will be refunded at the time of the monitor's photo shoot (approximately one month after the treatment).

Comparison with other treatment methods

Comparison with hyaluronic acid injection

PRPF: Autologous ingredients with low allergy risk and long-term skin regeneration effects
Hyaluronic acid: Immediate volumizing effect, but absorbed in 6-12 months. Also, there is a risk of vascular occlusion, and caution should be exercised when injecting near blood vessels, such as under the eyes and between the eyebrows.

2. comparison with laser treatment

PRPF: Deep skin action and long-lasting effects
Laser: mainly superficial effect, multiple treatments required

Comparison with surgical procedures

PRPF: Non-invasive, fast recovery, and natural-looking results
Surgical procedures: dramatic changes possible, but with greater risk and downtime

PRPF injection procedure

  1. Blood sampling: a small amount of blood is drawn from the patient's arm
  2. PRP extraction: PRP is extracted using a special centrifuge
  3. FGF addition: FGF is added to the extracted PRP
  4. Injection design: Individualized design according to the symptoms you want to resolve
  5. Injection: A fine needle is used to inject into the skin under the eyes.

The needles used are very thin to minimize pain. In addition, anesthesia cream can be used if necessary.

Precautions and Side Effects

PRPF injections are relatively safe, but may cause temporary side effects, including

Mild swelling and internal bleeding at the injection site
Temporary pain or discomfort

In rare cases, infection or inflammatory reactions may occur, but our strict hygiene and skilled techniques minimize these risks.

FAQ

Q1: Is PRPF injection painful?

A1: Most patients experience only mild discomfort due to the use of an extremely fine needle and anesthetic cream if necessary.

Q2: When will I start seeing results?

A2: Although there are individual differences, most people begin to notice gradual effects after 2 to 4 weeks. The greatest effect is often seen after 3-6 months.

Q3: How many times do I need to take the course?

A3: Usually, one treatment can be expected to last for 5 years or more.

summary

PRPF injections are an effective treatment for dark circles under the eyes. It is safe because it uses autologous ingredients and features natural-looking results. The complex mechanism of this treatment can be used to treat various types of dark circles, and long-term results can be expected.

At Smart Skin Clinic, we utilize our expertise in injectable procedures and regenerative medicine to provide the best PRP injections.

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