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Personalized PRP injections for hand rejuvenation treatment
In this article,Ministry of Health, Labour and Welfare – Accredited Facility for Regenerative Medicine Provision PlanSmart Skin Clinic, a cosmetic dermatology clinic, provides a clear, professional explanation.(*Type II and Type III Regenerative Medicine Provision Plan accreditation number: NA8230001)
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Do any of these concerns sound familiar?
For concerns like these,
personalized PRP injection is well suited.
Why PRP is effective for hand rejuvenation
The mechanism of aging on the back of the hands
With age, the skin on the back of the hands thins, collagen decreases, and blood flow declines. As a result, wrinkles become more noticeable, veins are more likely to show through, and the hands can look older.
Why PRP is effective for hand rejuvenation
PRP works to promote collagen production, improve blood flow, and increase skin thickness. As a result, it restores natural plumpness and makes visible veins less noticeable.
Growth factors in PRP activate fibroblasts, restoring firmness and elasticity to the skin.
Promotes the formation of new blood vessels and improves circulation, for healthier-looking hands with better color.
PRP thickens the dermal layer, helping reduce a bony appearance.
Case Photos (Before/After)
This is a case of a man in his 50s, 3 months after personalized PRP injection.
We assessed the whole face to design the treatment, then customized the injections to target areas with wrinkles.
This is a case of a woman in her 50s, 3 months after personalized PRP injection.
We assessed the whole face to design the treatment, then customized the injections to target areas with wrinkles.
Comparison with other hand treatments
| Treatment name | PRP injection | fat injection | Hyaluronic acid |
|---|---|---|---|
| Treatment details | PRP extracted from your own blood is injected to promote collagen production | Your own fat is harvested, processed, and injected into the back of the hand | Hyaluronic acid is injected beneath the skin to add volume |
| Results | Natural plumpness with no sense of discomfort | Adds volume, but retention can be inconsistent | Can look unnatural if overfilled |
| Duration | Lasts as long as 4 to 5 years | Semi-permanent, but the fat can be reabsorbed by the body | Re-injection needed roughly every 6 months to 1 year |
| Downtime | Virtually none (normal activities OK from the same day) | Long (swelling and bruising can last more than 2 weeks) | Swelling and bruising may occur for a few days |
| Safety | No foreign-body reaction, since it uses your own blood | Involves a degree of surgical risk, since fat must be harvested | Carries a risk of foreign body reaction |
| Treatment Time | Approx. 20 minutes | Approx. 1 to 2 hours | Approx. 30 minutes |
Features of Personalized PRP Injection
Our clinic's original "Personalized PRP injection"
Unlike standard PRP injections, our Personalized PRP injection is built around an approach tailored to each individual. We optimize three key factors to improve the naturalness of results, how long they last, and the precision of the procedure.
We assess the condition of your face and the back of your hands, then precisely plan exactly where, how deep, and how much to inject.
Using our proprietary recipe and protocol, we create the most effective PRP + FGF formulation to improve how long results last.
Our experienced doctors inject at the optimal depth, volume, and distribution for your skin type and bone structure, for a beautiful result.
Why patients choose Personalized PRP injection
Treatment Flow
*You are free to leave the clinic during this waiting period.
Pricing
The average price of PRP injections (for the hands) in Tokyo is 300,000 to 500,000 yen (as of February 2025).
Smart Skin Clinic'sPersonalized PRP Injectionprice list for
| Treatment details | Regular Price | Monitor price |
|---|---|---|
| Back of the hand (1 session) | 259,800 yen | 229,800 yen |
| Fingers (1 session) | 259,800 yen | 229,800 yen |
| Back of hand + fingers set | 449,800 yen | 399,800 yen |
Fingers (1 session):259,800 yen
Total:519,600 yen
you receive a 50,000 yen discount will apply.
Those seeking a more natural-looking result
Those who want solid results while keeping costs down
Monitor Requirements
①Intended Use｜We may feature your photos on our website, Instagram, or other media, or show them to other patients as treatment examples [please think of them as general case-study photos].
②Procedure｜You will pay the regular price at your first visit, and the difference (between the regular price and the monitor price) will be refunded when your monitor photos are taken (approximately 3 months after treatment as a guide)
Treatment details
・Those who are pregnant or breastfeeding (please consult your doctor before treatment)
You may notice mild pain or a lump-like sensation at the injection site, which can be eased with proper aftercare.
In rare cases, allergic reactions or tumor formation at the treatment site have been reported.
Results vary from person to person, and we cannot guarantee the same outcome for every patient.
**Our Personalized PRP injection uses a proprietary protocol designed to minimize these risks as much as possible, for a safer treatment.**
FAQ
Please feel free to discuss any questions with our doctors, who can recommend the best solution for your concerns.
Free Consultation
If you have any questions about the treatment, please feel free to reach out to us first.
Our doctor will propose the treatment plan best suited to you.
There is no sales pressure or upselling — a consultation alone is completely fine.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.