GOURI injection [PCL preparation

Campaign price in effect

GOURI Eye Catch

What are GOURI injections like?"
I'd like to get GOURI injections, but I'm concerned about the effects and the cost."

Do you have any of these problems?

Smart Skin Clinic, a cosmetic dermatology clinic, will explain GOURI injections in an easy-to-understand manner from a professional standpoint so that these concerns can be resolved.

*If you would like to know the fees and other information, you can skip to the table of contents below.


What is GOURI injection?

GOURI is an injectable formulation containing an ingredient called PCL (polycaprolactone).

GOURI's PCL is liquefied, making it the world's first "liquefied PCL formulation" to be developed.


Being transformed into a liquid rather than a solid.

What is GOURI?

What is PCL?

PCL will be a thread used in the medical field. Technically, it is called "biodegradable synthetic polymeric agent," which includes the meaning that it is dissolved and absorbed in the body. The word "polymer" is also a good one to note, and in the case of a polymeric component, volume enhancement can be expected.

Since PCL is a thread, it is a foreign substance to the body, causing a "foreign body reaction" in the body. This foreign body reaction stimulates fibroblasts in the skin (dermis), increasing and activating collagen and elastin, thereby producing a lifting effect.

This PCL is also a type of thread used in thread lifts. In the case of thread lift, the PCL is solid PCL, but GOURI's PCL is liquefied.

This ingredient, PCL, has been approved by the FDA (U.S. Food and Drug Administration) and CE (European safety standard) and has a high safety profile.

What is PCL?

Differences from conventional PCL formulations

PCL formulations other than GOURI have existed in the past.

However, conventional PCL is not liquefied, but solid (particulate), and thus carries the risk of vascular embolization and lumps.

The PCL formulation that eliminates these risks is GOURI.

Three Characteristics of GOURI (3S)

GOURI has the following three characteristics

  • Spredability
  • Sustainability
  • Safety

The 3Ss are an acronym for three characteristics.


(1) Spredability

Liquefied PCL is very diffusive. This provides two advantages

(1) Spreads over a wide area, so it is effective all over the place.
(2) Shorter treatment time due to the use of fewer injection sites to produce a wider range of effects.

(2) Sustainability

PCL aggregates in the skin (forming a 3-dimensional matrix) and increases and activates collagen in the mid- to long-term.

Specifically,About 6~12 monthsThe effect is sustained for a period of


PCL will be a safe ingredient approved by FDA and CE.

It is liquefied and has little risk of vascular embolization or lump formation.


GOURI has a variety of skin benefits.

  • Skin elasticity UP
  • lift up
  • tightening
  • Sagging Improvement
  • Under eye concavity
  • Improvement of wrinkles at the corners of the eyes
  • Improvement of cheek moss
  • Improvement of fine lines and wrinkles
  • Improvement of melasma

What is unique to GOURI in this,Highly effective in lifting and improving saggingThe following are some examples.

Case photos (before/after)

Case photo (1)
Case Photo (2)
Case photo (3)

Recommended number/frequency of treatments

It is recommended to perform 3~4 times with an interval of about 1 month. After that, maintenance is recommended in about 6 months to 1 year.

Treatment area/method

Treatment area

The three main treatment areas can be broadly summarized as follows

  • Forehead
  • Cheeks (around eyes, cheeks, mouth)
  • head

Treatment Method

The first premise is that there are two types of needles for injection used in GOURI as follows.

  • Sharp needle = pointed tip
  • Blunt needle = not pointed

In the GOURI procedure, the orange point in the figure below is pierced with (1) a sharp needle to make a hole in the skin.

GOURI Treatment Area

Next, (2) pass a blunt needle through the hole you just made. Then, GOURI is injected into the light blue area in the above figure.

There is pain when (1) a sharp needle penetrates the skin, but little pain when (2) a blunt needle is moved. Discomfort or pain may be felt when injecting the drug.

For the injection method shown in the figure, the recommended dosage is one bottle on each side, for a total of two bottles.

Those who cannot be treated

Pregnant or nursing mothers

Those with abnormal immune function or a history of such abnormality, and those undergoing immunosuppressive therapy.

Those prone to keloid formation, hypertrophic scars and hyperpigmentation

Those with bleeding tendency or using non-steroidal anti-inflammatory analgesics such as aspirin or anticoagulants such as warfarin

Excessive sunburn, eczema, dermatitis, acne with severe inflammation, or scabs at the site of JUVELUX VOLUME (RENISNA) injection

Risks/side effects

of the needle puncture site.

Redness, swelling, pain, edema

Intravascular hemorrhage

Temporary protuberance

of the injection site

Down time

Redness and bumps at the injection site may occur, but in most cases will return to normal within 48 hours.

Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, although not always. If subcutaneous bleeding spots occur, they will gradually disappear over a period of 10-14 days.


Since there are individual differences, the following is a general progression for reference.

several days later
Feel changes in skin luster, etc.

several weeks later
You also begin to feel a little lift and other effects.

After 1 month
The realization of effects such as lifting and increased skin elasticity will be greater.

After-sales service

Avoid strenuous exercise, saunas, bathing (showers are allowed), and alcohol consumption (in small amounts) for 24 hours after the procedure. It is recommended to reduce skin irritation and avoid strenuous activities for at least 3 days after the procedure.

Flow of treatment


You can easily make reservations with your mobile phone.

Reception (desk)

This is a "smart" and easy receptionist service that can be completed immediately by the clinic's IT system by simply providing your name.

Counseling and medical examination

Please feel free to discuss any concerns you may have during the counseling session. Please be assured that there is no pushy sales.

GOURI infusion

After the marking is carried out, the injection is carried out while talking to the patient.

After-sales service

We will explain in detail about the care of the treated area and precautions for daily life. We also suggest appropriate home care from the viewpoint of prevention and maintenance, such as oral medicines and skin care cosmetics that can be expected to improve your problems.

Returning home

Physician Comments

GOURI itself is not yet that famous in Japan, but it is a formulation that has been the topic of discussion at prestigious international conferences such as AMWC.

What is AMWC?

Abbreviation for Aesthetic & Anti-Aging Medicine World Congress.

The one and only international medical conference series with a reputation for bringing together the world's top cosmetic medicine and anti-aging specialists to share their expertise.

Official websitehttps://www.amwc-japan.com/


In actual practice, we feel that GOURI is a more comprehensive approach to the concerns of people in their 40s and beyond compared to other injectable formulations.

Please feel free to consult us if you have any problems with sagging, lifting, etc.


Campaign price in effect

1 bottle (1cc)69,800 yen →directional marker or indicator54,800 yen
Set of 2 (2cc)129,600 yen→directional marker or indicator 98,000 yen
3 sets179,400 yen→ 158,400 yen
(52,800 yen per bottle)
4 sets219,200 yen → 190,000 yen
(95,000 yen per two bottles)
Set of 6294,000 yen→ 269,400 yen
(89,800 yen per two bottles)
Set of 8392,000 yen→ 339,200 yen
(84,800 yen per two bottles)
  • 10,000 yen discount if available for monitoring (applicable for sets of 4 or more)
  • All tax included
  • Not covered by insurance, but free treatment.

Need for anesthesia|High

The price includes all fees for consultation, anesthesia, and needles. No additional fees will be charged on the day of the surgery.
*Because anesthesia is recommended for this procedure, it is basically standard to perform it after implementing cream anesthesia and local anesthesia.

Reference] How to choose the dosage

I've looked at a lot of websites, but I'm not sure what the dosage (cc) is."

We often hear this question, so we will provide an explanation in the form of a diagram. Although there are individual differences, there is an optimal dosage for each area, so the dosage required per treatment is summarized below for each area.

For example, if you want to lift up your cheeks, you will need 2 vials (2 cc) per treatment, and if you want to have a set of 3 treatments, you can choose a set of 6 vials for a good price.

Pattern (1)
GOURI dosage_amount
Pattern (iii)

More Information

Treatment Time20~30 minutes (not including counseling)
Recommended number and frequency of treatmentsIt is recommended to perform sets of 3 to 4 times at intervals of about 1 month.
After that, maintenance is recommended every 6 months to a year.
Down timeAbout 24 hours
Treatment on the day of counselingPossible
MakePossible immediately after the treatment
Skin carePossible immediately after the treatment
ShowerPossible from the same day
PainThere is a stinging pain when the needle is inserted.
Dull pain, like a slight push, during injection
*There are individual differences.

Legal description

GOURI treatment includes the use of medicines or medical devices that are not approved in Japan. The medicines and devices used in the treatment have been imported on a private import basis based on the judgment of our physicians.

Please refer to this page for information on medicines, etc. that should be noted for personal importation.
Ministry of Health, Labour and Welfare, "Medicines, etc. that Require Caution in Personal Importation".

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Smart Skin Clinic

Smart Skin Clinic

The concept of the clinic is to "make cosmetic medicine more accessible and smart. is the concept of the clinic.

Instead of eliminating ornate interiors to reduce interior design costs and installing equipment in the dark, we carefully select the equipment we need and reduce the cost of the equipment.

We aim to "make cosmetic medicine more accessible" for you.

Clinic Reception

Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)

Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)

About the physician supervision of this site

About the physician supervision of this site

This site is operated under the supervision of the Smart Skin Clinic supervising physicians.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.