PRPF injection [Wrinkles and indentations of the forehead (forehead)
I heard that PRP injections are effective for wrinkles on the forehead, but are they really effective? How safe is it?"
I hear that injections of PRP with added FGF are dangerous."
I just want to improve the wrinkles and indentations on my forehead."
I want to do something about the wrinkles on my forehead, so I am comparing various options such as Botox injections and hyaluronic acid injections. But I'm wondering if there is a way to do it that doesn't compromise my natural facial expression..."
Hello. I am a doctor at Smart Skin Clinic, a cosmetic dermatology clinic. I am sure you all have these questions and concerns.
In this article,Ministry of Health, Labour and WelfareThe clinic is a cosmetic dermatology clinic that specializes in the treatment of skin cancer. (* Type 2 and Type 3 Regenerative Medicine Provision Plan, Approval Number: NA8230001)
*If you would like to know the rates, you can jump to the appropriate section from the table of contents below.
What are PRPF injections?
PRPF injection is a treatment in which a preparation of PRP (platelet-rich plasma) with FGF (fibroblast growth factor) is injected.
PRP: An ingredient extracted from your own blood and rich in growth factors
FGF: Fibroblast growth factor. An ingredient that strongly promotes skin regeneration.
The combination of the two is more effective than conventional PRP therapy.
Role of growth factors (growth factors)
Growth factor is a general term for proteins and peptides that promote cell growth, division, and differentiation. They are of particular interest in cosmetic medicine and play a major role in skin rejuvenation and regeneration.
Major growth factors include the following
- EGF (epidermal growth factor): helps skin regeneration
- FGF (Fibroblast Growth Factor): Increases collagen and elastin to plump up the skin
- IGF (insulin-like growth factor): creates new cells and reduces damage caused by aging
Mechanism of PRPF injection: Why does it work for forehead wrinkles?
PRPF injections work on forehead wrinkles mainly because of the following five mechanisms
1. promotion of collagen production
Platelet-derived growth factor (PDGF) and FGF contained in PRP stimulate fibroblasts. As a result, collagen production is promoted, improving skin firmness and elasticity. This improves sagging skin that causes wrinkles on the forehead.
2. promotion of elastin production
FGF also promotes the production of elastin. Elastin is an important protein that maintains skin elasticity, and its increase improves the expression lines on the forehead.
3. improvement of skin thickness
The dermal layer of the skin is thickened by the action of PRP. This reduces the appearance of forehead indentations and gives an overall youthful appearance.
4. blood circulation promotion
Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. Blood circulation is improved and skin metabolism is activated.
5. tightening of pores and improvement of shine
The skin regenerating action of growth factors is also effective in tightening pores on the forehead. In addition, the activation of cells on the skin surface leads to a naturally shiny forehead.
Three features of PRPF injections
1. natural rejuvenation effect
Because autologous ingredients are used, the result is natural. Because it enhances the skin's natural regenerative powers, it does not have the stiffness of Botox-like expressions.
2. customized treatment
Our clinic will adjust the concentration and amount of PRP injected to meet the skin conditions and goals of each individual client, and will design the injection individually.
3. long-term effectiveness and cost performance
The effect usually lasts more than 5 years. Because of the long-lasting effect of a single treatment, it is cost-effective.
PRPF injections are recommended for
- Those who are concerned about wrinkles on the forehead
- Those who have noticeable expression wrinkles.
- Concerned about forehead indentation
- Those concerned about open pores on the forehead
- Those who want to achieve naturally shiny forehead skin.
- Those who want a natural finish.
- Worried that Botox will stiffen facial expressions
Features of PRPF Injection at Smart Skin Clinic
1. specialist in injectable procedures
Optimal infusion through extensive experience and advanced technology
Unique injection technique to minimize pain
Personalized and customized treatment for each customer
2. expert in regenerative medicine
Regenerative Medicine Provider approved by the Ministry of Health, Labour and Welfare (obtained a Type 2 Regenerative Medicine Provision Plan No.)
Utilization of the latest findings by board-certified physicians of the Japanese Society of Anti-Aging Medicine
3. superiority in combining expertise in injectable and regenerative medicine
More effective and safer treatment
Optimal treatment plans tailored to the client's condition and wishes.
Charge
PRPF Injection Prices in Tokyo
The price of PRPF injections in Tokyo is200,000 to 400,000 yen(as of August 1, 2024). (as of August 1, 2024)
Smart Skin Clinic Fee Schedule
| Once | 208,000 yen |
| Monitor] 1 time | 178,000 yen |
| Price per site for more than 2 sites (face) | 166,400 yen (20%OFF from regular price) |
| Monitor] 2nd site (face) | 136,400 yen |
We are a free clinic and not covered by insurance.
The price is indicated as all-inclusive, including consultation and needle fees.
There is no separate upsell on the day of the event.
Monitoring Requirements
(i)Usage｜We may post the photos on our website, Instagram, etc. with the eye area hidden, or show them to other customers as examples of treatment [please think of them as general case photos].
(2)implementation method｜The difference (between the regular price and the monitor price) will be refunded at the time of the monitor's photo shoot (approximately one month after the treatment).
Comparison with other treatment methods
Comparison with hyaluronic acid injection
PRPF: Autologous ingredients with low allergy risk and long-term skin regeneration effects
Hyaluronic acid: Immediate volumizing effect, but absorbed in 6-12 months. Also, there is a risk of vascular occlusion, and caution should be exercised when injecting near blood vessels, such as under the eyes and between the eyebrows.
2. comparison with laser treatment
PRPF: Deep skin action and long-lasting effects
Laser: mainly superficial effect, multiple treatments required
Comparison with surgical procedures
PRPF: Non-invasive, fast recovery, and natural-looking results
Surgical procedures: dramatic changes possible, but with greater risk and downtime
PRPF injection procedure
- Blood sampling: a small amount of blood is drawn from the patient's arm
- PRP extraction: PRP is extracted using a special centrifuge
- FGF addition: FGF is added to the extracted PRP
- Injection design: Individualized design according to the symptoms you want to resolve
- Injection: A fine needle is used to inject into the skin under the eyes.
The needles used are very thin to minimize pain. In addition, anesthesia cream can be used if necessary.
Precautions and Side Effects
PRPF injections are relatively safe, but may cause temporary side effects, including
Mild swelling and internal bleeding at the injection site
Temporary pain or discomfort
In rare cases, infection or inflammatory reactions may occur, but our strict hygiene and skilled techniques minimize these risks.
FAQ
Q1: Is PRPF injection painful?
A1: Most patients experience only mild discomfort due to the use of an extremely fine needle and anesthetic cream if necessary.
Q2: When will I start seeing results?
A2: Although there are individual differences, most people begin to notice gradual effects after 2 to 4 weeks. The greatest effect is often seen after 3-6 months.
Q3: How many times do I need to take the course?
A3: Usually, one treatment can be expected to last for 5 years or more.
summary
PRPF injections are an effective treatment to improve wrinkles and indentations on the forehead. It is safe because it uses autologous ingredients and features natural-looking results.
At Smart Skin Clinic, we utilize our expertise in injectable procedures and regenerative medicine to provide the best PRP injections.