Personalized PRP injections for the treatment of laugh lines
When I look in the mirror, I notice the lines on my face..."
I want to fix my smile lines...but I want to do it naturally and without discomfort."
I want to avoid surgical treatments like thread lifts or cutting procedures..."
I don't like to repeat a procedure over and over again..."
Do you have any of these concerns or wishes regarding your smile lines?
Our personalized PRP injections are a procedure with the following features and may be able to meet these concerns and desires.
- Non-Invasive Cosmetic Procedures
- Because it is not hyaluronic acid, it does not cause discomfort and is a natural change
- Completed in only one basic session
- Effectiveness is more than 4~5 years
- Downtime is almost only on the same day. Makeup OK on the same day.
In this article,Ministry of Health, Labour and WelfareSmart Skin Clinic, a cosmetic dermatology clinic that specializes in cosmetic dermatology, will provide a professional and easy-to-understand explanation of the process.
(* Type II and Type III Regenerative Medicine Provisioning Plans Accreditation Number: NA8230001)
For those with these concerns
- Lines become deeper, giving the impression of aging at once...
- I'm worried that hyaluronic acid might look unnatural...
- We want to avoid surgery and extensive treatment...
- I don't want people to find out, so I prefer a procedure with short downtime.
- I like long-lasting treatment with long-lasting effects.
For those who have these concerns, ourPersonalized PRP Injectionhave been selected.
Case study photographs (Before/After)
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
What is personalized PRP injection?
PRP injections at our clinicPersonalized PRP injections are a procedure that has evolved through original research and technology.It is.
PRP injections are natural rejuvenation treatments that utilize growth factors extracted from your own blood to stimulate collagen production.
PRP: An ingredient extracted from your own blood that contains growth factors.
FGF: Fibroblast growth factor. An ingredient that strongly promotes skin regeneration.
✅ Natural finish."Rejuvenates the skin itself, rather than increasing volume like hyaluronic acid.
✅ One and done."Unlike many procedures, it can essentially be completed in a single session.
✅ Long-lasting effects."Effects last approximately 4 to 5 years, with little need for repeat treatments.
✅ Non-Surgical TreatmentNo scalpel and almost no downtime
Difference from hyaluronic acid injections
| feature | Personalized PRP Injection | hyaluronic acid injection |
|---|---|---|
| finish | It restores natural firmness and elasticity, achieving a natural rejuvenation effect. | Adds volume directly, with immediate effect. |
| Duration | The effect lasts for a long period of time, approximately 4 to 5 years. | It takes about 6 months to 1 year and requires regular treatments. |
| Main action | Autologous blood-derived growth factors promote collagen production and improve skin texture. | Injected under the skin as a filler, it physically lifts wrinkles and sagging skin. |
| Frequency of treatment | Long-term effects can be expected from a single treatment. | Periodic reinjection is necessary to maintain the effect. |
| Safety | Because autologous blood is used, the risk of allergy is low and the procedure is considered safe. | In rare cases, allergic reactions or foreign body sensations may occur. |
Personalized PRP injections are regenerative medicine using your own blood, rather than injecting solid substances. Since your own skin is regenerated, the effect lasts longer than hyaluronic acid.
In addition, because it is not solid, it is virtually impossible for it to cause discomfort.
Mechanism of personalized PRP injections: why do they work for laugh lines?
The main reasons why personalized PRP injections are effective for lines areFour mechanismsDepends on the
1. promotion of collagen production
Platelet-derived growth factor (PDGF) and FGF contained in PRP stimulate fibroblasts. As a result, collagen production is promoted, improving skin firmness and elasticity. This improves sagging skin that causes laugh lines.
2. promotion of elastin production
FGF also promotes elastin production. Elastin is an important protein that maintains skin elasticity, and its increase makes the skin in the area of the lines more flexible.
3. improvement of skin thickness
The dermal layer of the skin is thickened by the action of PRP. This reduces the appearance of lines and gives an overall youthful impression.
4. blood circulation promotion
Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. Blood circulation is improved and skin metabolism is activated. This results in an overall improvement in skin texture around the laugh lines.
The combined action of these mechanisms is effective in improving the appearance of lines.
Personalized PRP Injection Features
Flow of treatment
Please feel free to discuss any concerns or wishes you may have. There is no sales or up-selling at our clinic, so just a consultation is perfectly acceptable.
We will examine your current condition in detail in terms of whether you are eligible for personalized PRP injections and how we can design them to improve your appearance naturally. *This is included in the free consultation.
As the name "personalization" suggests, each person's face is different and the condition they wish to achieve is also different. Therefore, we will design your face individually and carefully. Our skilled eye will create the most suitable design for you.
PRP is a regenerative medicine using your own blood. You can imagine it as a normal blood draw.
PRP is extracted and processed from the client's own blood at our in-house processing facility. This is a delicate and time-consuming process that requires the client to wait approximately one hour. (You may leave the clinic at any time).
Since anesthesia is administered prior to the procedure, there is almost no pain during PRP injection.
Based on the pre-assumed design, we precisely inject "(1) the appropriate amount of PRP, (2) in the targeted area, and (3) at the optimal depth.
You may go home immediately after the procedure is completed. There will be some redness around the injection site, but it will not be noticeable because it is the redness of a tipsy person.
Charge
PRP Injection Prices in Tokyo
The price of PRPF injections in Tokyo is200,000 to 400,000 yenThe number of employees is as follows. (as of February 2025)
Smart Skin Clinic Fee Schedule
| Once | 208,000 yen |
| Monitor] 1 time | 178,000 yen |
| Price per part for more than 2 parts | 166,400 yen (20%OFF from regular price) |
| Monitor] 2nd site | 136,400 yen |
All-inclusive prices are shown, including consumption tax, consultation fee, and needle fee.
There is no separate upsell on the day of the event.
Monitoring Requirements
(i)Usage｜We may post the photos on our website, Instagram, etc. with the eye area hidden, or show them to other customers as examples of treatment [please think of them as general case photos].
(2)implementation method｜The difference (between the regular price and the monitor price) will be refunded at the time of the monitor's photo shoot (approximately one month after the treatment).
Risks and Side Effects
Although PRPF injections are relatively safe, the following side effects may occur
Mild swelling and internal bleeding at the injection site
Temporary pain or discomfort
lump
We minimize these risks through strict hygiene and skilled techniques.
FAQ
- How long will the effect last?
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Lasts 4-5 years. It lasts longer than hyaluronic acid and does not require frequent maintenance.
- Is there pain?
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The use of an ultrafine needle causes almost no pain. Block anesthesia and other techniques are also used.
- Is there any downtime?
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There may be some redness at the injection site, but it will settle down in a few hours. Most of the time, this will only occur on the same day. Makeup can be applied on the same day.
- When will the effects start to show?
-
Since this is a procedure that regenerates your own skin, the effects are gradual: you will begin to feel the effects in about 1 to 2 weeks, with a maximum in 3 months, which lasts about 4 to 5 years.
summary
Personalized injections are an effective treatment for improving lines. It is safe because it uses autologous ingredients and features natural-looking results.
Smart Skin Clinic offers personalized PRP injections, drawing on its expertise in injection-based procedures and regenerative medicine.
Since effects and durations vary from person to person, we recommend an individual consultation for more details. We will work with you to find the best method of improving your smile lines.