Personalized PRP injection [Improvement of laugh lines
I've heard that PRP injections are effective in treating laugh lines, but do they really work? How safe is it?"
I hear that injections of PRP with added FGF are dangerous."
I just want to improve my lines."
"I want to do something about my smile lines, and I am comparing various options such as hyaluronic acid injections, facelifts, and thread lifts. But I'm afraid of surgery, and I'm wondering if there is a way to achieve a natural finish..."
Hello. I am a doctor at Smart Skin Clinic, a cosmetic dermatology clinic.
Do you have any of these questions or concerns?
In this article,Ministry of Health, Labour and WelfareThe following is an easy-to-understand explanation from a professional standpoint by a cosmetic dermatology clinic that is a member of the "Aesthetic Dermatology Clinic".
(* Type II and Type III Regenerative Medicine Provisioning Plans Accreditation Number: NA8230001)
*If you would like to know the rates, you can jump to the appropriate section from the table of contents below.
What are personalized PRP injections?
PRPF injections are,Treatment by injecting a preparation containing FGF (fibroblast growth factor) added to PRP (platelet-rich plasma)It is.
PRP: An ingredient extracted from your own blood and rich in growth factors
FGF: Fibroblast growth factor. An ingredient that strongly promotes skin regeneration.
The combination of the two is said to have a greater effect on the dermis than conventional PRP therapy.
Case study photographs (Before/After)
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
Name of treatment Personalized PRP injection: Before Before treatment, After treatment After 1 treatment
Treatment Details Personalized PRP Injection is an injection procedure that combines PRP (Plasma Reconstituted Platelets) extracted from one's own blood with growth factors (FGF). It aims to improve deep wrinkles such as laugh lines and marionette lines by enhancing the skin's ability to regenerate. In addition, this treatment supports the skin's firmness and elasticity, giving it a more youthful appearance. The procedure is personalized to each patient's concerns and skin type, so a higher level of satisfaction can be expected.
Duration and number of treatments Usually only one treatment is performed *In some cases, additional treatments may be performed if the effect is not satisfactory.
Major Risks and Side Effects Mild redness, swelling, and internal bleeding may occur after injection, but usually resolves within a few days. Mild pain or a lumpy sensation may be felt at the injection site, but this is relieved with proper aftercare. Rarely, allergic reactions or tumor formation at the treatment site may be reported. Effectiveness varies from person to person and we cannot guarantee the same results for all patients.
Price of treatment 136,400 - 208,000 yen *Price range is due to the existence of monitor plans
Role of growth factors (growth factors)
Growth factor is a general term for proteins and peptides that promote cell growth, division, and differentiationIt is. It has received particular attention in cosmetic medicine, where it contributes to skin rejuvenation and regeneration.
There is more than one growth factor.
Major growth factors include the following
- EGF (epidermal growth factor): helps skin regeneration
- FGF (Fibroblast Growth Factor): Increases collagen and elastin to plump up the skin
- IGF (insulin-like growth factor): creates new cells and reduces damage caused by aging
These growth factors act to :
Increase collagen: Skin becomes more elastic and resilient.
Repairing cells: Treats damaged skin.
Improves blood circulation: delivers plenty of nutrients and oxygen to the skin
Safety of PRP +FGF injection
There are two types of academic societies for cosmetic surgery in Japan. The first is the JSAPS, and the second is the JSAS.
Each of the directors made the following references to PRP +FGF injections
Dr. Hiroko Hayashi
Director, Japanese Society of Aesthetic Plastic Surgery (JSAPS)
It has been pointed out that there are some problems such as lumps at the site of injection, but I believe it can be a very beneficial treatment if done under strict criteria.
(Source.) Aesthetic Hifco NEWS "PRP + bFGF, what do you think of the guideline's cautious policy? ─ Interview with Hiroko Hayashi, Director of Gioia Clinic Kyoto, the first half"
Dr. Tatsuro Kamakura
President of the Japanese Society of Aesthetic Surgery (JSAS)
There is no such thing as a universal cure in the world.
The treatment method has not only benefits (main effects) but also
It is also something that has disadvantages (side effects),
That balance is important.As of that time, Sacred Heart's premium PRP treatment with
The "overinflated" is kept to less than 1 percent.
Therefore, it should be administered with caution,
That is my opinion.
(Source.)note Tatsuro Kamakura｜ Chief Director, Sacred Heart Aesthetic Clinic｜ President, Japanese Society of Aesthetic Plastic Surgery (JSAS)
There is so much information out there that it is difficult to determine what is "right". However, we believe that the stance of the head of the Society of Cosmetic Surgery can be a reliable source of information for everyone.
To add a little more, there is no such thing as "completely zero risk" in any medical treatment. Take, for example, the major treatment methods of hyaluronic acid injections and Botox.
Hyaluronic acid injections risk skin necrosis and blindness if vascular embolization occurs. Botox has the risk of difficulty in opening the eyes and facial expressions.
However, it has become popular as a good treatment. This is because the risks can be reduced to almost zero if performed with the correct injection technique.
PRP+FGF injections, like hyaluronic acid injections, can be a very beneficial treatment if done under strict criteria as the JSAPS President says.
Mechanism of personalized PRP injections: why do they work for laugh lines?
The main reasons why PRP injections are effective for lines areFour mechanismsDepends on the
1. promotion of collagen production
Platelet-derived growth factor (PDGF) and FGF contained in PRP stimulate fibroblasts. As a result, collagen production is promoted, improving skin firmness and elasticity. This improves sagging skin that causes laugh lines.
2. promotion of elastin production
FGF also promotes elastin production. Elastin is an important protein that maintains skin elasticity, and its increase makes the skin in the area of the lines more flexible.
3. improvement of skin thickness
The dermal layer of the skin is thickened by the action of PRP. This reduces the appearance of lines and gives an overall youthful impression.
4. blood circulation promotion
Vascular endothelial growth factor (VEGF) promotes the formation of new blood vessels. Blood circulation is improved and skin metabolism is activated. This results in an overall improvement in skin texture around the laugh lines.
The combined action of these mechanisms is effective in improving the appearance of lines.
Three features of personalized PRP injections
1. natural rejuvenation effect
Because autologous ingredients are used, the result is natural. Because it enhances the skin's natural regenerative power, it is not unnatural.
2. personalized treatment
Our clinic will adjust the concentration and amount of PRP injected to meet the skin conditions and goals of each individual client, and will design the injection individually.
3. duration and cost performance
Considering the mechanism of PRPF injections, we can expect medium- to long-term effects because the improvement is achieved by approaching the inside of the skin.
*The duration of the effect varies from person to person.
Personalized PRP injections are recommended for
Those who are concerned about laugh lines.
Those who have noticeable expression lines and wrinkles
Those who are concerned about sagging cheeks
Overall skin elasticity
Those who want to regain elasticity
Those who want a natural finish.
Features of our personalized PRP injections
1. clinics that specialize in injectable procedures
Our clinic focuses on injectable procedures and has accumulated knowledge and experience in this area.
Injection techniques to reduce pain
Personalized treatment for each customer
2. expertise in the area of regenerative medicine
Regenerative Medicine Provider approved by the Ministry of Health, Labour and Welfare (obtained a Type 2 Regenerative Medicine Provision Plan No.)
Specialist in the Society of Anti-Aging Medicine
3. providing treatments that combine expertise in injectable and regenerative medicine
Leveraging experience in injection systems and knowledge of regenerative medicine
Personalized treatment plans tailored to the client's condition and wishes
Charge
PRPF Injection Prices in Tokyo
The price of PRPF injections in Tokyo is200,000 to 400,000 yen(as of August 1, 2024). (as of August 1, 2024)
Smart Skin Clinic Fee Schedule
| Once | 208,000 yen |
| Monitor] 1 time | 178,000 yen |
| Price per part for more than 2 parts | 166,400 yen (20%OFF from regular price) |
| Monitor] 2nd site | 136,400 yen |
We are a free clinic and not covered by insurance.
The price is indicated as all-inclusive, including consultation and needle fees.
There is no separate upsell on the day of the event.
Monitoring Requirements
(i)Usage｜We may post the photos on our website, Instagram, etc. with the eye area hidden, or show them to other customers as examples of treatment [please think of them as general case photos].
(2)implementation method｜The difference (between the regular price and the monitor price) will be refunded at the time of the monitor's photo shoot (approximately one month after the treatment).
Comparison with other treatment methods
Comparison with hyaluronic acid injection
PRPF: Autologous ingredients with low allergy risk and long-term skin regeneration effects
Hyaluronic acid: Immediate volumetric effect, but resorbed in 6-12 months. Also, there is a risk of vascular occlusion and caution is required.
Comparison with Botox injections
PRPF: Improves the skin texture itself and maintains a natural look
Botox: temporarily paralyzes facial muscles, which may result in a stiffer expression.
Comparison with facelift
PRPF: Non-invasive, fast recovery, and natural-looking results
Facelift: dramatic changes are possible, but surgical risks and downtime are high.
Personalized PRP Injection Procedure
- Blood sampling: a small amount of blood is drawn from the patient's arm
- PRP extraction: PRP is extracted using a special centrifuge
- FGF addition: FGF is added to the extracted PRP
- Injection design: We will implement the most appropriate design according to your concerns.
- Injection: A fine needle is used to inject into the skin around the laugh lines.
The needles used are very thin to minimize pain. In addition, anesthesia cream can be used if necessary.
Risks and Side Effects
Although PRPF injections are relatively safe, the following side effects may occur
Mild swelling and internal bleeding at the injection site
Temporary pain or discomfort
lump
We minimize these risks through strict hygiene and skilled techniques.
FAQ
Q1: Is PRPF injection painful?
A1: Most patients experience only mild discomfort due to the use of an extremely fine needle and anesthetic cream if necessary.
Q2: When will I start seeing results?
A2: Although there are individual differences, most people begin to notice gradual effects after 2 to 4 weeks. The greatest effect is often seen after 3-6 months.
summary
PRPF injections are an effective treatment for improving lines. It is safe because it uses autologous ingredients and features natural-looking results. A complex mechanism is used to address the lines, and long-term results can be expected.
Smart Skin Clinic offers personalized PRP injections, drawing on its expertise in injection-based procedures and regenerative medicine.
Since effects and durations vary from person to person, we recommend an individual consultation for more details. We will work with you to find the best method of improving your smile lines.