![Official] Smart Skin Clinic｜Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)
Jalpro Super Hydro Injection｜Smart Skin Clinic [Official]
| Sessions (2.5 cc) | Price | per 1 ccPrice |
|---|---|---|
| Once | 59,800 yen | 23,900 yen |
| 2 sessions | 109,600 yen (54,800 yen per session) | 21,900 yen |
| 3 times | 149,400 yen (49,800 yen per session) | 19,900 yen |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Jalupro Super Hydro is a "skin-nurturing injection" that can help address sagging without surgery. For those concerned about a sagging jawline, jowls, and loss of firmness. Smart Skin Clinic explains the mechanism behind its natural tightening and skin-quality improvement through ligament reinforcement.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What is Jalupro Super Hydro?
Ingredients and mechanism of action (skin-nurturing injection and bio-remodeling action)
Jalupro Super Hydro isNon-cross-linked hyaluronic acid, amino acids, and peptidesIt is a "skin-nurturing injection" made up of these three groups of ingredients.
- non-cross-linked hyaluronic acidBy combining two types with different molecular weights (high molecular weight: 2000 kDa; low molecular weight: 200 kDa), it can be expected to bring moisture retention and elasticity to the superficial and deep layers respectively.
- Amino acidsincludes seven types (glycine, proline, lysine, leucine, alanine, valine, and arginine) and is an important component that supports fibroblasts and forms the foundation for collagen production.
- PeptidesFormulated with three types (Acetyl Decapeptide-3, Oligopeptide-24, and Acetyl Tetrapeptide), it can promote the cell activation involved in skin regeneration and firming.
By working on the skin's foundation (the dermis), these combined ingredients aim for "structurally beautiful skin" with moisture, firmness, and elasticity. Jalupro Super Hydro isThis is an injectable treatment that offers the potential to improve the quality of the skin itself.
Differences from conventional hyaluronic acid injections and thread lifts
Unlike hyaluronic acid injections centered on "volume replenishment" or thread lifts centered on "physical traction," Jalupro Super Hydro's core is "bioremodeling" that harnesses your own healing power. Because tissue reconstruction progresses after injection, the result is remarkably natural with little unevenness. Furthermore, by uniformly hydrating all layers of the skin, it can improve skin quality at the same time, so even as a standalone treatment it can be expected to bring out the skin's inherent, multifaceted beauty.
Who is it recommended for? (Suitable concerns and areas)
- Concerned about sagging along the jawline
- A thread lift helped temporarily, but the sagging has come back...
- Bothered by hollow cheeks, but worried that hyaluronic acid might leave them looking overfilled...
- Worried that a thread lift might cause dimpling or tightness...
How long do the effects last? (Duration)
The effects of Jalupro Super Hydro typically begin with a sense of hydration immediately after injection, followed from around 2 to 3 weeks later by improved elasticity through fibroblast activation, generally lasting 3 to 6 months. As treatments are repeated, collagen density increases and the period of stable results can be expected to lengthen. Maintenance injections every six months can help keep the sense of lift and improved skin quality over the long term. There is individual variation, but the duration may be extended further depending on your post-treatment lifestyle and skincare.
Causes of Sagging
As we age, the following changes occur in the skin and the tissues beneath it.
- Outer skin: stretches
- Inner collagen and elastin: decrease
- Inner fat tissue: atrophies
- Inner bone: recedes
- Ligaments (supporting ligaments) that connect the outer and inner layers: stretch and loosen
These factors do not act in isolation; they interact with one another to produce sagging.
The history of Jalupro (development background and safety)
Background to the development of the Jalupro formulation
"Jalupro," the base of Jalupro Super Hydro, was born as a formulation from Italy. In the early 2000s, physicians who focused on the combination of "non-crosslinked hyaluronic acid + amino acids" for skin reconstruction developed it as an injection to restore the skin's inherent beauty from within. It was subsequently introduced in many countries, including across Europe and Asia, and the Jalupro series has grown into a range of formulations able to address skin concerns across a wide range of ages.
The emergence and evolution of Super Hydro
Jalupro Super Hydro was developed as the latest evolution in the series. It contains a higher ratio of non-cross-linked hyaluronic acid and amino acids than earlier products, and three types of peptides have been newly added. These ingredients support the production of collagen and elastin, which are involved in skin elasticity, and in addition to improved skin quality and moisturizing effects, a growing number of people report a sense of "skin tightening" and "reduced jawline slackness." Some physicians have also reported using injections into the ligament (supporting ligament) areas for structural support, making it a suitable option for those concerned about mild sagging.
European approval and safety track record
Jalupro Super Hydro has obtained the "CE mark," the safety standard required in the European Union, and has a track record of use in medical settings. Across the entire Jalupro line, it has been used in more than 1.5 million procedures in over 70 countries worldwide, making it a product that has built long-term trust. The hyaluronic acid used for injection is non-crosslinked, and the fact that it is less likely to cause lumps or excessive swelling is another reason patients can feel confident about the treatment.
Jalupro Super Hydro's Threepoints
①Expect a natural tightening of the facial contour (tightening through ligament reinforcement)
Jalupro Super Hydro is a formulation designed to give three-dimensional firmness to loosened tissue and help tighten the facial contour by injecting it around the "ligaments" that support the facial structure. Unlike surgical facial-contour tightening, its approach is to "refine from the foundation" while preserving natural expressions. Among injectable treatments, it is an option offering a natural-looking result for those who are beginning to notice sagging or heaviness in the cheeks.
②Can be expected to improve skin quality (enhancing moisture, firmness, and radiance)
Jalupro Super Hydro contains non-crosslinked hyaluronic acid together with a well-balanced blend of seven amino acids and three peptides involved in the skin's structure. As these act on the dermal layer, the balance of the skin's moisture, elasticity, and radiance is more easily restored from within. Formulated to address "overall signs of skin aging" such as dry skin, uneven texture, and fine lines, some people feel their skin looks smoother and more refined after treatment.
③Short downtime (makeup possible from the day after treatment)
One reason Jalupro Super Hydro is chosen is that it involves relatively little post-treatment downtime. As it is an injection-based treatment, very mild redness or swelling may occur, but these generally become inconspicuous within 1 to 2 days. In most cases makeup can be applied the very next day, making it easy to fit in for busy people or those who want to schedule treatment around work. It is also a reassuring choice for those considering their first injectable treatment.
Treatment areas for Jalupro Super Hydro
Jalupro Super Hydro is a treatment that primarily targets the ligaments of the face. For this reason, recommended points are chosen so that the active ingredients reach the facial ligaments efficiently.
Approximately 0.1 to 0.2 ml is used per site across 13 points each on the face and neck, for a total of about 2.5 ml of Jalupro Super Hydro.
The following two diagrams (first: face, second: neck) show the representative areas where Jalupro Super Hydro is injected. By injecting particularly around the ligaments where sagging is a concern, the aim is to achieve natural tightening.
Jalupro Super Hydro'sRecommended Number & Frequency of Treatments
About three sessions at one-month intervals are recommended. After that, maintenance about once every six months to a year is recommended.
The Jalupro Super Hydro treatment process
You can easily book from your smartphone.
It is a "smart," simple reception process without complicated procedures.
The Jalupro Super Hydro treatment begins with counseling by a physician. We never push you to have the treatment, so you are welcome to visit even if you only want a consultation.
For Jalupro Super Hydro injections, a physician who understands the skin's structure and the position of the ligaments carefully injects the product into a shallow or slightly deeper layer according to the goal. To bring out a natural sense of lift and firmness, the injection volume and points may be designed individually. The injection typically takes about 15 to 30 minutes in total. We aim to create an environment where you can relax while we value conversation with you throughout.
After treatment, we explain any necessary precautions. Jalupro Super Hydro is a same-day treatment that lets you go home the same day, and face washing and makeup are usually possible from the next day. As a basic rule, vigorous massage, long baths, and excessive alcohol should be avoided for several days, but no special care is required.
For Your Daily Care
To every day beyond,
Skin-nurturing care.
&DR.is a skincare brand born from the findings of cosmetic dermatology. Its first product, BAKU, is a skin-nurturing serum that focuses on gentleness, centered on the plant-derived skin-conditioning ingredient BAKUCHIOL. It can be used gently every day, both in the morning and at night.
Frequently Asked Questions (FAQ)
- What is the difference between Jalupro and Super Hydro?
-
Jalupro comes in several types: the Classic is suited to areas such as around the eyes, while Jalupro Super Hydro has a composition that adds peptides to hyaluronic acid and amino acids, with its distinctive feature being the potential for skin tightening through injection into the ligaments.
- When do the effects of Jalupro Super Hydro begin to appear?
-
Many people find it easy to feel added moisture right after the injection and notice a change in firmness and tightness within about one to two weeks. Jalupro Super Hydro is characterized by working gradually on the skin's structure.
- What are the drawbacks of Jalupro Super Hydro?
-
Bruising and swelling may occur in rare cases, but because it uses non-cross-linked hyaluronic acid, lumps are unlikely and downtime is relatively short. Jalupro Super Hydro has a formulation designed with safety in mind.
- Is Jalupro effective under the eyes?
-
Dedicated formulations such as Jalupro Classic and Jalupro Eye are commonly used under the eyes. Jalupro Super Hydro is more often used to tighten the skin of the cheeks, jawline, and neck.
- How much downtime is there? Can I return to my normal routine right after the treatment?
-
Temporary redness or swelling may occur after the Jalupro Super Hydro treatment, but in most cases it settles within one to two days. Downtime is relatively short, and makeup can be applied from the next day.
- How many sessions do I need? What is the recommended frequency and interval?
-
Typically, three treatments performed at one-month intervals form the basic course. After that, maintenance every six months is recommended. With Jalupro Super Hydro, repeated sessions can help stabilize the skin structure.
- How is Jalupro Super Hydro different from Profhilo?
-
The effects are similar, but strictly speaking, the areas they target are different. The main target of Jalupro Super Hydro is the ligaments (supporting ligaments). The main targets of Profhilo are collagen and elastin production in the dermis and the activation of fat cells in the subcutaneous tissue.
- Can anyone receive this treatment? Are there age limits or cases where it cannot be performed (such as pre-existing conditions or pregnancy)?
-
Generally, it is intended for healthy individuals aged 18 and over.Jalupro Super HydroIt is not recommended for those who are pregnant or breastfeeding, or who have severe skin conditions or serious illness. A physician will confirm suitability before the treatment.
Risks and side effects of Jalupro Super Hydro
What side effects can occur after injection? (swelling, bruising, redness)
Jalupro Super Hydro is a minimally invasive injectable treatment, but mild side effects may occur right after the procedure. Common ones include swelling, redness, bruising, and a feeling of tightness at the injection site. These are natural biological reactions and most settle within a few days.
Bruising in particular is more likely in areas where the skin is thin, and many people return to daily life while covering it with makeup. Any pain during the procedure is also very mild and can be reduced further with anesthetic cream.
Rare risks and cases requiring caution
The non-crosslinked hyaluronic acid, amino acids, and peptides used in Jalupro Super Hydro may, on rare occasions, cause allergic reactions or skin discomfort. If you have experienced skin trouble from cosmetic injections in the past, or have a hypersensitivity to medications, please be sure to consult a physician beforehand.
In addition, as with any injection, there is a very rare risk of infection or inflammation. To minimize these risks, it is important to receive treatment at a reliable medical institution and to avoid firmly touching or rubbing the area after treatment.
What you can do to minimize side effects
After the Jalupro Super Hydro treatment, you can minimize the risk of side effects by being mindful of a few things. On the day of treatment, avoid strenuous exercise, alcohol, and long baths, and refrain from excessively boosting your metabolism and blood flow.
It is also ideal to avoid actions that place strong pressure on the injection site (massage, sleeping face-down, etc.) for two to three days. If you are pregnant, breastfeeding, or have skin problems, consult your physician in advance about whether the treatment is suitable, and prepare so you can receive it with peace of mind.
Those who are not eligible for the treatment
Jalupro Super Hydro is Treatment cannot be provided if any of the following apply.
- Those who are pregnant or breastfeedingThose who are
- At the treatment siteInfection, severe inflammation, or herpesThose with skin conditions such as
- Severe autoimmune diseaseandBleeding disordersThose whose general condition is unstable, such as serious heart or kidney disease
- Anticoagulants or antiplatelet agentsThose taking medications that increase bleeding risk, such as the above, without approval from their treating physician
- In the pastAllergic reaction to hyaluronic acid preparations or peptide-based injectionsThose who have experienced
Also,Impaired barrier function immediately after intense sunburn or due to severe atopic dermatitisIf any of these are present, the timing of the treatment may be postponed. To ensure safe treatment, please always inform your physician of any pre-existing conditions, current medications, and life events (such as trying to conceive) at the time of counseling. If you have any questions, discussing them in advance allows us to propose a more suitable treatment plan.
Smart Skin Clinic Pricing
| Sessions (2.5 cc) | Price | per 1 ccPrice |
|---|---|---|
| Once | 59,800 yen | 23,900 yen |
| 2 sessions | 109,600 yen (54,800 yen per session) | 21,900 yen |
| 3 times | 149,400 yen (49,800 yen per session) | 19,900 yen |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Summary
Jalupro Super Hydro is an injection that supports the ligaments while raising the baseline quality of the skin—a "structural" approach to bringing out the skin's inherent beauty.
At Smart Skin Clinic, physicians examine and treat you directly without a counselor in between. We do not engage in any selling or upselling. We have created an environment where you can consult us with peace of mind. Please feel free to come in for a consultation first.
(Note)Details
| Treatment Time | About 15 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | - About three times at one-month intervals - After three sessions, maintenance in six months to one year is recommended |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | From the next day |
| Skincare | From the next day |
| Shower | Possible from the same day |
| Pain | A slight pricking sensation when the needle is inserted. |
(Note)Legal Notices
Jalupro Super Hydro treatment includes procedures using pharmaceuticals or medical devices that are not approved in Japan. The pharmaceuticals and devices used in the treatment are personally imported under the judgment of our physicians.
Disclosure of the approval status of the drug in Japan: Jalupro Super Hydro is an unapproved drug in Japan.
The drugs and medical devices used in this treatment are not approved within Japan; they are provided based on their track record of use and safety information in other countries. Specifically, Jalupro Super Hydro has obtained the "CE mark," the safety standard required in the European Union, and has a track record of use in medical settings. Across the entire Jalupro line, it has been used in more than 1.5 million procedures in over 70 countries worldwide, making it a product that has built long-term trust.
For this reason, it is not eligible for relief under Japan's "Relief System for Adverse Drug Reactions."
Please refer to this page for information on medications and similar items that require caution in personal importation.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising Guidelines Medical Advertising Guidelines revised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last supervision date: June 26, 2025