![Official] Smart Skin Clinic｜Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)
Personalized PRP Injection for Nasolabial Folds
Those pesky nasolabial folds.
In one goThe effects last for about 5 yearsdo
We offer treatments.
Treatment Name: Personalized PRP Injection (A treatment that involves injecting PRP and growth factors derived from the patient’s own blood to improve nasolabial folds and other concerns) / Price: 136,400–208,000 yen (tax included) / Major Risks and Side Effects: Redness, swelling, bruising, mild pain, or a sensation of a lump after the injection (these typically subside within a few days). Results may vary from person to person.
Nasolabial foldsAre you curious about this?
It deepens with ageNasolabial folds.With hyaluronic acid and thread lifts,I'm worried it might look unnatural...
No cutting, and it feels completely natural,Reduce nasolabial folds naturallyThere is a way to improve this.
- Without using a scalpel,Natural finish
- It's completed in a single session, andoffering long-lasting results of 4 to 5 years
- Virtually no downtime,Makeup on the day of the event is also OK
- Since we make use of the eigencomponents,No feeling of a foreign object—peace of mind
Number of PRP Treatment Cases
1,000and more
*Jimbocho Branch (Eligibility Period: June 2023 – March 14, 2026) and Yokohama Branch (Eligibility Period: July 2025 – March 14, 2026)
| Menu | Regular Price | 10/31Limited-time discount until (20% off) |
| Once | 166,400 yen | |
| Monitor 1 session | 142,400 yen | |
| Second area (face) | ¥133,120 | |
| Monitor Second Area (Face) | ¥109,120 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Compared to other clinics in Tokyo
Price for a Single PRP Injection with Growth Factors for Nasolabial Folds
Average of 7 clinics in Tokyo211,200 yen
Our Clinic's Prices Through October 31166,400 yen
Our Clinic's Trial Price142,400 yen
If the price is the same as it was through October 31,
From other hospitals44,800Great Deal
If you're looking for a promotional price,
From other hospitals68,800Great Deal
These figures represent the difference per visit compared to the Tokyo average.
Participation in the trial requires, among other things, the provision of case photos (see the "Fees" section below for details).
*Average price (including tax) for a single PRP injection containing growth factors into nasolabial folds at seven cosmetic clinics in Tokyo. Calculated based on the standard prices listed on each clinic’s website and other sources (as of October 2026, according to our clinic’s survey). Our clinic’s price is valid through October 31 and includes all fees, such as the consultation fee and the cost of the needles.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
For those with these concerns
- My nasolabial folds have deepened, andIt makes me look a lot older all of a sudden…
- Hyaluronic acid isI'm worried it might look unnatural...
- Surgery and major medical treatments areI want to avoid that…
- Since I don't want anyone to find out,I prefer treatments with minimal downtime.
- Want a treatment with long-lasting results
For those of you who are facing these kinds of challenges,Our clinic's personalized PRP injectionsIt has been selected.
Personalized PRP injections
Two Reasons Why We're the Top Choice
In just one session,Lasts about 4 to 5 years
Hyaluronic acid injections are absorbed within about half a year to one year, so repeat treatments are necessary. With personalized PRP injections, the effects typically last about 4 to 5 years after a single treatment.
My CellsSince it plays,
Hard to noticeNatural finish
Instead of injecting foreign substances to fill in wrinkles, components derived from your own blood regenerate skin tissue. This minimizes the risk of unnatural swelling caused by over-injection, allowing you to achieve a natural-looking rejuvenation that is unlikely to be noticed by others.
*Results and duration may vary from person to person.
What Is Personalized PRP Injection?
PRP (platelet-rich plasma) is,Extracted from your own blood,This ingredient is rich in growth factors.
By enhancing the skin's own regenerative ability,It improves nasolabial folds at their root.
STEP 01
Blood Draw
We will draw a small amount of blood. The procedure is the same as for a regular blood test.
STEP 02
Purification
We purify PRP to a high concentration and blend it with growth factors (FGF).
STEP 03
Injection
It precisely injects the appropriate amount into the optimal layer.
Injection
Fill in
Filling in the lines with hyaluronic acidPhysically push up. It is broken down and absorbed by the body, andIt takes about half a year to a year to return to normal..
PRP injection
Raise
Growth factors derived from your own blood,Promotes collagen production in the skin. The changes occur gradually, andTypically lasts about 4 to 5 years per treatment.
*This is an illustrative image. Results and duration may vary from person to person.
PRP contains platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and other factors that promote collagen production, improve blood flow, and facilitate cell repair.
Difference from hyaluronic acid injections
| Comparison point | ＼ Our Treatments ／Personalization PRP injection | Hyaluronic acid Injection |
|---|---|---|
| structure | Using components derived from one's own blood,Building an Organization | Use the preparation to create a groovePhysically fills |
| Sustainability Guideline | About 4 to 5 yearsUsually only once | About half a year to one yearAbsorbed by the body |
| Per Cost | 166,400 yenPrice valid through October 31 | About 50,000 yenPer 1 cc* |
| Total cost Total amount | 166,400 yenOnly once | Approximately 250,000 yenOnce a year × 5 times |
| Results | ◎Changes in the Scope of Your Organization's Growth | △Overfilling can result in an unnatural-looking bulge |
| downstream Time | ◎Virtually none; you can resume your normal daily activities the same day | ○May cause bruising or swelling |
| Foreign Body Reaction | ◎Since the patient's own blood is used, there is no foreign body reaction. | △Carries a risk of foreign-body reaction |
| Treatment Time | Approx. 20 minutes | Approx. 15-30 min. |
*The cost of hyaluronic acid is based on the median price (as of September 2026, according to our clinic’s survey) for one syringe (1 cc) of hyaluronic acid used to treat nasolabial folds at 11 clinics in Tokyo. The total cost over five years is calculated based on one injection per year. Our clinic’s price includes all fees, such as the consultation fee and needle cost. Results and duration of effect may vary from person to person.
We recommend PRP for those who want a natural, seamless result.
Causes of nasolabial folds and how PRP works
The causes of nasolabial folds are,It's not just sagging.
Loss of skin elasticity, fat atrophy,Since this results from cumulative volume loss,Comprehensive care isThis leads to a fundamental solution.
Three actions of PRP
Features of Personalized PRP Injection
Personalized treatment
Regenerative Medicine Provider
Cases by Age Group
For those concerned about nasolabial folds,
These are the changes observed after a single treatment session.
Treatment Name: Personalized PRP Injection (A treatment that involves injecting PRP and growth factors derived from the patient’s own blood to improve nasolabial folds and other concerns) / Price: 136,400–208,000 yen (tax included) / Major Risks and Side Effects: Redness, swelling, bruising, mild pain, or a sensation of a lump after the injection (these symptoms typically subside within a few days). Results may vary from person to person. The photos are posted with the consent of actual patients who have undergone the procedure at our clinic.
Pricing
| Menu | Regular Price | 10/31Limited-time discount until (20% off) |
| Once | 166,400 yen | |
| Monitor 1 session | 142,400 yen | |
| Second area (face) | ¥133,120 | |
| Monitor Second Area (Face) | ¥109,120 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Prices are shown all-inclusive, covering consultation and needle fees.
There is no separate upselling on the day.
Monitor Requirements
①Intended Use| We may publish the photos on our website, Instagram, and similar media with the eye area concealed, or show them to other patients as treatment examples [please picture typical case photos].
②Procedure｜You will pay the regular price at your first visit, and the difference (between the regular price and the monitor price) will be refunded when your monitor photos are taken (approximately 3 months after treatment as a guide)
First of all,You're welcome to just come in for a free consultation.
"I'm nervous about deciding on a treatment right away..."That's what most people say.
Counseling at our clinic is,This is not intended to be a treatment.
- Sales and Upselling areNone at all
- "Just listen to what I have to say,We also welcome you to “take your time to consider it at home.”
- Includes a doctor's consultation.Whether it applies or not, andAll the way through to assessing the final resultI can confirm that
- All-inclusive, covering consultation fees and other costsTransparent pricing.There are no additional charges on the day of the event.
Reception Hours: Weekdays 11:00 a.m.–8:00 p.m. / Saturdays and Sundays 10:00 a.m.–7:00 p.m.
Treatment Flow
Regarding your concerns and requests,Please feel free to ask us about anything.At our clinic, sales and upselling areSince there isn't any,It's perfectly fine to just come in for a consultation.
Personalized PRP InjectionsWhether it applies or not,How should I design it?Will I be able to do it naturally,From that perspective, the current situation is...We will conduct a thorough examination.*Included in the free consultation.
As the name “Personalize” suggests,Everyone's skin condition is different, andThe desired outcomes also differ.Therefore, we will handle each case carefully and individuallyWe will handle the design.We use our expert eye to create the optimal design.
PRP uses your own bloodThis falls under the category of regenerative medicine.Just imagine a regular blood drawIt's okay.
(Waiting time: about 1 hour)
From the customer's own blood,At the on-site processing facilityWe perform PRP extraction and processing.This is a delicate process, andSince this will take some time,It will take about an hour for our customersYou will need to wait.(You are free to go out.)
Based on the design we had envisioned beforehandThe appropriate amount of PRPAt the optimal location and depthWe will inject it with precision.
If you have any questions, please consult directly with a physician
To help ease any concerns as much as possible, at our clinic
During a free consultation, a doctor will speak with you directlyHere is my answer.
Whether or not to undergo the treatment depends on,
Please take your time to consider it after that.
There is absolutely no sales or upselling.
Treatment details
・Those who are pregnant or breastfeeding (please consult your doctor before treatment)
You may experience mild pain or a sensation of a lump at the injection site, but these symptoms are usually temporary and can be alleviated with proper aftercare.
In very rare cases, allergic reactions or the formation of tumors at the treatment site have been reported. If you experience any concerning symptoms, a doctor will examine you directly and provide appropriate care.
Results vary from person to person, and the same outcome cannot be guaranteed for every patient.
*Please note that the growth factor (bFGF) preparation used in this treatment is considered off-label for cosmetic purposes and is not covered by the Pharmaceutical Side Effect Victim Relief System.
Our personalized PRP injection uses a proprietary protocol to minimize these risks to the greatest extent possible,
providing a safer treatment.
FAQ
How many treatments are needed?
Basically, treatment is completed in a single session. Results vary by individual, but many patients are satisfied with the outcome after just one treatment.
Do personalized PRP injections hurt?
Anesthesia is applied before treatment, so there is little to no pain. If you have any concerns, please consult us beforehand.
How much downtime is there?
There is virtually no downtime. Some redness may appear right after treatment, but it usually settles down within a few hours.
Can I apply makeup right after the treatment?
You should avoid strong stimulation to the injection site on the day of treatment, but you can wear makeup as usual starting the next day.
Can personalized PRP injections be used for areas other than nasolabial folds?
Yes, it’s possible. We can treat a wide range of areas, including dark circles under the eyes, forehead wrinkles, sunken eyes, wrinkles around the mouth, and the backs of the hands. If there are any areas you’re concerned about, please feel free to consult with us.
Are there any side effects or risks?
Because your own blood is used, there is virtually no risk of a foreign body reaction. That said, mild redness or swelling may occur after treatment, but it typically settles down within a few days.
Please feel free to reach out first
We welcome your questions, concerns, and free counseling bookings regarding Personalized PRP injection.
We'll propose the treatment plan best suited to your concerns.
There is never any high-pressure sales, so please consult with us with confidence.
Our Commitment to Addressing Your Skin Concerns
Various facial concerns, such as,It's not just a matter of appearance...No.For daily joy and a sense of self-worthI think this is an important issue that concerns us all,I'm thinking about it.
As we get older ourselves,"I wonder if my nasolabial folds have gotten a little deeper...""My dark circles are a little noticeable today, so I might look tired..."I even found myself worrying about that.
Just one change in your face,Fashion and interpersonal relationshipsI started to enjoy it, andTo enjoy life even moreYou might find yourself able to do it.
We offer personalized PRP injections,It's not just about improving the appearance, but rather,A Positive Outlook on Life ItselfA trigger for being caughtWe consider this to be a treatment that will result in...
Under the supervision of a board-certified specialist in anti-aging medicine,No sales or upsellingWe are fully committed to providing sincere medical care.
It is true that this is a costly treatment.But more than that,"I want to enjoy the rest of my life more."For customers who think,Delivering Tangible Value"Investment"If that is the case,We are convinced.
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising Guidelines Medical Advertising Guidelines revised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last Reviewed: August 1, 2026