Personalized PRP Injection for Nasolabial Folds

| Menu | Regular Price | Limited-time discount through 8/31 (20%Off) |
| Once | 166,400 yen | |
| Monitor 1 session | 142,400 yen | |
| Second area (face) | ¥133,120 | |
| Monitor Second Area (Face) | ¥109,120 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Nasolabial foldsAre you curious about this?
It deepens with ageNasolabial folds.With hyaluronic acid and thread lifts,I'm worried it might look unnatural...
No cutting, and it feels completely natural,Reduce nasolabial folds naturallyThere is a way to improve this.
- Without using a scalpel,Natural finish
- It's completed in a single session, andoffering long-lasting results of 4 to 5 years
- Virtually no downtime,Makeup on the day of the event is also OK
- Since we make use of the eigencomponents,No feeling of a foreign object—peace of mind
In this article,Ministry of Health, Labour and Welfare – Accredited Facility for Regenerative Medicine Provision PlanisSmart Skin Clinic, a cosmetic dermatology clinic,From a professional standpointI'll explain it in simple terms.
(*Type II and Type III Regenerative Medicine Provision Plans) Certification Number: NA8230001)
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
For those with these concerns
- My nasolabial folds have deepened, andIt makes me look a lot older all of a sudden…
- Hyaluronic acid isI'm worried it might look unnatural...
- Surgery and major medical treatments areI want to avoid that…
- Since I don't want anyone to find out,I prefer treatments with minimal downtime.
- Want a treatment with long-lasting results
For those of you who are facing these kinds of challenges,Our clinic's personalized PRP injectionsIt has been selected.
Case Photos (Before/After)





Before: Before Treatment
After: Following the completion of one treatment session
| Treatment period and number of sessions | Typically, only one treatment session is required*In cases where the results are insufficient, additional treatments may be performed. |
|---|---|
| Treatment price | 136,400 yen to 208,000 yen*The price range varies because there is a trial plan. |
- Mild redness, swelling, or bruising may occur after the injection, but these symptoms usually subside on their own within a few days.
- You may experience mild pain or a sensation of a lump at the injection site, but these symptoms are usually temporary and can be alleviated with proper aftercare.
- In very rare cases, allergic reactions or the formation of tumors at the treatment site have been reported. If you experience any concerning symptoms, a doctor will examine you directly and provide appropriate care.
- Results vary from person to person, and we cannot guarantee the same outcome for every patient.
Number of PRP Treatment Cases
1,000and more
*Jimbocho Branch (Eligibility Period: June 2023 – March 14, 2026) and Yokohama Branch (Eligibility Period: July 2025 – March 14, 2026)
What Is Personalized PRP Injection?
PRP (platelet-rich plasma) is,Extracted from your own blood,This ingredient is rich in growth factors.
By enhancing the skin's own regenerative ability,It improves nasolabial folds at their root.
STEP 01
Blood Draw
We will draw a small amount of blood. The procedure is the same as for a regular blood test.
STEP 02
Purification
We purify PRP to a high concentration and blend it with growth factors (FGF).
STEP 03
Injection
It precisely injects the appropriate amount into the optimal layer.
PRP contains platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and other factors that promote collagen production, improve blood flow, and facilitate cell repair.
Guiding you to the solution that’s best for you,Four Points of Personalization
Rather than relying solely on a doctor's judgment,In every step of the processBacked by clinical data.
So, the end result isIt's stable and natural.
Personalized Diagnosis
Based on case dataAnalyze body structure and skin condition.Is PRP really the best option?We'll assess the situation before making a proposal.
Personalized Purification
Based on numerous clinical results,We have derived,Our clinic’s proprietary purification protocol.
Personalized Design
The tissue lifts most naturallyCalculate the position and quantity, andFirst, create the design plan, then proceed with the treatment.
Personalized Injection
Across the entire groupOver 24,000 injections performed annually.The right amount to the right layer,We'll deliver it right on target.
Difference from hyaluronic acid injections
| Comparison point | Personalized PRP Injection | Hyaluronic acid injections |
|---|---|---|
| Treatment details | Injects PRP extracted from your own blood to promote skin regeneration | Injects synthetic hyaluronic acid to add volume |
| Results | Natural firmness and plumpness | Overfilling can result in an unnatural-looking bulge |
| Duration | Lasts as long as 4 to 5 years | Absorbed within roughly 6 months to a year |
| Downtime | Virtually none (normal activities OK from the same day) | May cause bruising or swelling |
| Safety | No foreign-body reaction, since it uses your own blood | Carries a risk of foreign-body reaction |
| Treatment Time | Approx. 20 minutes | Approx. 15-30 min. |
Treatment details
Results
Duration
Downtime
Safety
Treatment Time
We recommend PRP for those who want a natural, seamless result.
Causes of nasolabial folds and how PRP works
The causes of nasolabial folds are,It's not just sagging.
Loss of skin elasticity, fat atrophy,Since this results from cumulative volume loss,Comprehensive care isThis leads to a fundamental solution.
Three actions of PRP
Features of Personalized PRP Injection
Personalized treatment
Regenerative Medicine Provider
Pricing
| Menu | Regular Price | Limited-time discount through 8/31 (20%Off) |
| Once | 166,400 yen | |
| Monitor 1 session | 142,400 yen | |
| Second area (face) | ¥133,120 | |
| Monitor Second Area (Face) | ¥109,120 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Prices are shown all-inclusive, covering consultation and needle fees.
There is no separate upselling on the day.
Monitor Requirements
①Intended Use| We may publish the photos on our website, Instagram, and similar media with the eye area concealed, or show them to other patients as treatment examples [please picture typical case photos].
②Procedure|You will pay the regular price at your first visit, and the difference (between the regular price and the monitor price) will be refunded when your monitor photos are taken (approximately 3 months after treatment as a guide)
First of all,You're welcome to just come in for a free consultation.
"I'm nervous about deciding on a treatment right away..."That's what most people say.
Counseling at our clinic is,This is not intended to be a treatment.
- Sales and Upselling areNone at all
- "Just listen to what I have to say,We also welcome you to “take your time to consider it at home.”
- Includes a doctor's consultation.Whether it applies or not, andAll the way through to assessing the final resultI can confirm that
- All-inclusive, covering consultation fees and other costsTransparent pricing.There are no additional charges on the day of the event.
Reception Hours: Weekdays 11:00 a.m.–8:00 p.m. / Saturdays and Sundays 10:00 a.m.–7:00 p.m.
Treatment Flow
(Waiting time: about 1 hour) From the customer's own blood,At the on-site processing facilityWe perform PRP extraction and processing.This is a delicate process, andSince this will take some time,It will take about an hour for our customersYou will need to wait.(You are free to go out.)
If you have any questions, please consult directly with a physician
To help ease any concerns as much as possible, at our clinic
During a free consultation, a doctor will speak with you directlyHere is my answer.
Whether or not to undergo the treatment depends on,
Please take your time to consider it after that.
There is absolutely no sales or upselling.
Treatment details
・Those who are pregnant or breastfeeding (please consult your doctor before treatment)
You may experience mild pain or a sensation of a lump at the injection site, but these symptoms are usually temporary and can be alleviated with proper aftercare.
In very rare cases, allergic reactions or the formation of tumors at the treatment site have been reported. If you experience any concerning symptoms, a doctor will examine you directly and provide appropriate care.
Results vary from person to person, and the same outcome cannot be guaranteed for every patient.
*Please note that the growth factor (bFGF) preparation used in this treatment is considered off-label for cosmetic purposes and is not covered by the Pharmaceutical Side Effect Victim Relief System.
Our personalized PRP injection uses a proprietary protocol to minimize these risks to the greatest extent possible,
providing a safer treatment.
FAQ
How many treatments are needed?
Basically, treatment is completed in a single session. Results vary by individual, but many patients are satisfied with the outcome after just one treatment.
Do personalized PRP injections hurt?
Anesthesia is applied before treatment, so there is little to no pain. If you have any concerns, please consult us beforehand.
How much downtime is there?
There is virtually no downtime. Some redness may appear right after treatment, but it usually settles down within a few hours.
Can I apply makeup right after the treatment?
You should avoid strong stimulation to the injection site on the day of treatment, but you can wear makeup as usual starting the next day.
Can personalized PRP injections be used for areas other than nasolabial folds?
Yes, it’s possible. We can treat a wide range of areas, including dark circles under the eyes, forehead wrinkles, sunken eyes, wrinkles around the mouth, and the backs of the hands. If there are any areas you’re concerned about, please feel free to consult with us.
Are there any side effects or risks?
Because your own blood is used, there is virtually no risk of a foreign body reaction. That said, mild redness or swelling may occur after treatment, but it typically settles down within a few days.
Please feel free to reach out first
We welcome your questions, concerns, and free counseling bookings regarding Personalized PRP injection.
We'll propose the treatment plan best suited to your concerns.
There is never any high-pressure sales, so please consult with us with confidence.
Our Commitment to Addressing Your Skin Concerns
Various facial concerns, such as,It's not just a matter of appearance...No.For daily joy and a sense of self-worthI think this is an important issue that concerns us all,I'm thinking about it.
As we get older ourselves,"I wonder if my nasolabial folds have gotten a little deeper...""My dark circles are a little noticeable today, so I might look tired..."I even found myself worrying about that.
Just one change in your face,Fashion and interpersonal relationshipsI started to enjoy it, andTo enjoy life even moreYou might find yourself able to do it.
We offer personalized PRP injections,It's not just about improving the appearance, but rather,A Positive Outlook on Life ItselfA trigger for being caughtWe consider this to be a treatment that will result in...
Under the supervision of a board-certified specialist in anti-aging medicine,No sales or upsellingWe are fully committed to providing sincere medical care.
It is true that this is a costly treatment.But more than that,"I want to enjoy the rest of my life more."For customers who think,Delivering Tangible Value"Investment"If that is the case,We are convinced.
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising Guidelines Medical Advertising Guidelines revised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last supervision date: June 26, 2025
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