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Exosome Penis Injection Therapy" Penile Cavernous Injection (ICI), a radical treatment for ED
So that more people can experience ED treatment through regenerative medicine,
we offer "30% OFF the treatment cost" for first-time visitors only.Please see the details below.
Take this opportunity to experience a consultation and treatment by a physician.
| Plan | Regular Price | First-time price (30% OFF) |
|---|---|---|
| Once | ¥49,800 | 34,860 yen (tax included) |
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Do any of these concerns sound familiar?
At the root of your concerns, there may be a medical cause, such as "impaired blood flow" or "aging of the tissue."
At our clinic,A treatment that addresses these issues through the power of regenerative medicineWe are carrying out the following.
What is Exosome Penile Injection Therapy?
What is an exosome?
Exosomes are extremely small, capsule-like substances secreted by cells,that play an important role in cell-to-cell communication and in tissue repair and regeneration.they carry out.
Because of their high capacity for regeneration and repair,they are a noteworthy ingredient whose use is expanding in the fields of anti-aging and cosmetic medicine..
At our clinic, we apply the power of these exosomes to ED treatment, aiming for more natural and fundamental improvement.
Why inject into the penis?
The tissues involved in erection, such as "blood vessels, nerves, and smooth muscle," decline in function with age.
By injecting exosomes directly into the corpus cavernosum of the penis,their high regenerative and restorative power acts on the tissue, helping to promote the recovery of blood flow, nerve function, and cellular function,.
making possible a medical approach to regaining your "natural erection."
Treatment features
- The option of "fundamental treatment" that does not rely on drugs
- A treatment considered to have few side effects
- An incision-free, short injection procedure (as little as 10 minutes)
Through the approach of regenerative medicine, we make ED treatment possible without relying on drugs.
The effects of exosomes on the penis
Improved erectile strength through better blood flow
The action of exosomes helps promote the repair and formation of blood vessels within the penis, which is expected to improve blood flow.
As a result,improved firmness and staying power of erectionsare anticipated.
Restored sensitivity through nerve regeneration
Exosomes may also act on the nervous system, which becomes less responsive with age and stress.
Improved sensory acuity and sexual responseare anticipated, bringing a positive change to the time you spend with your partner.
Rejuvenation of overall function through tissue regeneration
By promoting the regeneration of smooth muscle and the tissue itself,fundamental improvement of ED and a preventive approachare also anticipated uses.
Unlike temporary oral medications,it is a treatment aimed at "restoring your original function"that is the greatest strength of exosome therapy.
Scientific evidence for exosome ED treatment
- In human clinical studies, IIEF-5 improved by an average of +5.1 points improvement[1]
- Once a week × 4 times dosing produced greater recovery than a single dose[3]
- In a diabetic ED model, regeneration of blood flow and smooth muscle was confirmed[2]
Open study details
von Schwarz et al. (2021)In a human clinical trial, 20 men with a history of ED of at least one year received a single injection of stem cell-derived exosomes, and their IIEF-5 scores improved significantly from an average of 12.9 to 18.0 after 6 months.[1].
Chen et al. (2017)reported that, in a type 2 diabetes rat model, exosome injection markedly improved erectile function (ICP/MAP ratio), penile smooth muscle and endothelial markers, and anti-apoptotic markers.[2].
Kim et al. (2024)In a study using a rat model of nerve injury, four weekly exosome doses restored erectile function more clearly than a single dose, and increases in nNOS and cGMP concentrations were also confirmed.[3].
References
- von Schwarz ER, et al. Intracavernous injection of stem cell-derived bioactive molecules for erectile dysfunction: a pilot phase non-randomized controlled trial. J Men’s Health. 2021;17(4):99-108. Official page
- Chen F, et al. Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes. J Sex Med. 2017;14(9):1084-1094. PubMed
- Kim MY, et al. Repeated injections of MSC-derived exosomes ameliorate erectile dysfunction in a cavernous nerve injury rat model. World J Men’s Health. 2024;42:787-796. PubMed
Through a consultation with a physician, we will recommend the treatment best suited to you.
Please feel free to reach out to us first.
Our clinic hasno sales or upselling whatsoever.
We will listen carefully to your concerns and anxieties.
Why is exosome injection therapy effective?
Addressing the root causes of ED
The main causes of ED are reduced blood flow, declining nerve function, and aging of the tissue.
Conventional oral treatment provides only temporary relief of symptoms,whereas exosomes act on those underlying causes.
A mechanism of regeneration and repair
Because exosomes help promote cell repair and regeneration within the body,they may help restore erectile function in a natural wayare available.
"Fundamental treatment," not symptomatic treatment
ED medications are a means to "achieve an erection right now," whereas exosome therapyaims to "restore your original function again,"which isthe regenerative medicine approach.
That's exactly why,with the potential to contribute to long-term improvement and prevention as wellare available.
Rather than a superficial fix,it aims for improvement from a fundamental, medical standpoint.
Exosome injection therapy is a form of regenerative medicine.
Differences from other ED treatments
Oral treatment (e.g., Viagra)
- Fast-acting, but the effect is only temporary and does not amount to fundamental treatment
- In some cases, side effects such as palpitations or headaches may occur
Surgical procedures (e.g., implants)
- Effects on erectile function (excessive scarring can reduce the erection angle or cause deformity)
- Risks such as reduced sensation have also been noted
- Because a foreign object is inserted into the body, there is a risk of infection or rejection
Exosome injection therapy
- A fundamental treatment that uses your own regenerative capacity, without inserting any foreign substances
- Almost zero risk of infection, combining safety and a natural approach
- The potential to restore erectile function to its "natural state"
Precisely because there are so many treatment options,safety, fundamental improvement, and a natural approachthe balance among these is important.
Exosome injection therapy is an option with the potential to fulfill all of these.
Our commitment to ED treatment
ED is not merely a matter of physical function.
It is a sensitive and important topic, deeply connected to confidence, partnership, and the overall fulfillment of life itself.
We ourselves, as we have grown older, have experienced changes that we did not feel in our teens and early twenties.
We feel it is far from uncommon for people to have "a little ED," even if not complete ED.
In fact, the number of people with ED in Japan is estimated at approximately14 millionIt is said that there are many people of all ages who wonder, "Isn't there a way to solve this fundamentally, without relying on drugs and without risk?"
There are many people of all ages who wonder whether their concerns can be resolved fundamentally, without relying on drugs and without risk.
To address such concerns with care, our clinic
has a board-certified urologist and a board-certified anti-aging medicine specialist on staff to oversee Exosome Penile Injection Therapy.so it does.
So that men, too, can visit with peace of mind,our space is designed with careful attention to the interior and patient flow,and we provide a smart treatment experience free from the stress of long waits and discomfort.
So that each and every person can live positively, in their own way.
We arecommitted to ED treatment that values medical evidence and honest dialogue.We will continue to dedicate ourselves to this.
Features of our Exosome Penile Injection Therapy
Pricing
For first-time patients, instead of the regular price of 49,800 yen (tax included),first session 34,860 yen (tax included)is available.
| Penis (ED improvement) | |
|---|---|
| Once | 49,800 yen |
| 3 times | 143,400 yen (47,800 yen per session) |
| 5 sessions | 224,000 yen (per session 44,800yen) |
FAQ
Will my erections become better or firmer than they are now?
Rather than a temporary aid like medication,it is a treatment aimed at restoring your essential function.
Is there any pain during treatment?
We can also accommodate requests for anesthesia,so please rest assured, even if you feel anxious.
How long does the treatment take?
Does it work even at an older age?
It depends on the condition of your blood vessels and tissue, so please consult a physician first.
I'm in my 20s. Can I still receive it?
A growing number of people receive it for mild ED or to enhance performance.
Can it be combined with other treatments (such as oral medications)?
Will I be unable to donate blood?
Is MISEV supported?
So that more people can experience ED treatment through regenerative medicine,
we offer "30% OFF the treatment cost" for first-time visitors only.Please see the details below.
Take this opportunity to experience a consultation and treatment by a physician.
| Plan | Regular Price | First-time price (30% OFF) |
|---|---|---|
| Once | ¥49,800 | 34,860 yen (tax included) |
Through a consultation with a physician, we will recommend the treatment best suited to you.
Please feel free to reach out to us first.
Our clinic hasno sales or upselling whatsoever.
We will listen carefully to your concerns and anxieties.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.