Rejuran Generic (PDRN) | Japan's Lowest Price: 19,800 yen (price per session for a 4-session) | Smart Skin Clinic

Our clinic's free consultation is conducted directly by specialist doctors, not by beauty counselors as at large clinics. As a result, there is absolutely no hard selling during the free consultation, which makes it very popular with those trying aesthetic treatments for the first time. Please feel free to book with peace of mind.
Japan's Lowest Prices for Rejuran Generic (Kiarareju)
Rejuran Generic (Kiarareju)
*A polynucleotide (PDRN) preparation similar to Rejuran
| 1 vial (2.2cc) | |
|---|---|
| 1 session | 24,800 yen |
| 3-session set | 68,400 yen (22,800 yen per session) |
| 4-session set | 79,200 yen (19,800 yen per session) |
| 2 vials (4.4cc) | |
|---|---|
| 1 session | 34,800 yen |
| 3-session set | 92,400 yen (30,800 yen per session) |
| 4-session set | 115,200 yen (28,800 yen per session) |
| 3 vials (6.6cc) | |
|---|---|
| First time | 36,800 yen |
| 1 session | 39,800 yen |
| 3-session set | 104,400 yen (34,800 yen per session) |
| 4-session set | 131,200 yen (32,800 yen per session) |
Need for anesthesia | High
The price includes all costs, including anesthesia.
This treatment is recommended with anesthesia, so it is standard to perform it with cream anesthesia and local anesthesia.
Why we can offer "high quality" at "Japan's lowest standard prices"
In fact, more than 90% of aesthetic clinics carry too many unnecessary costs, which prevents them from offering the best prices to their customers.
Based on this awareness of the problem, we have built an aesthetic clinic that is completely different from conventional wisdom.
(1) Locations with low rent
(2) Reducing lavish interiors
(3) Reducing excessive staffing
(4) Reducing excessive advertising costs
This allows us to achievehigh-quality Rejuran generic injections at Japan's lowest standard prices, which other clinics cannot imitate.
Smart Skin Clinic's Rejuran Generic consistently earns high ratings in reviews on Google, Hot Pepper, Kirei Pass, and more.
At Smart Skin Clinic, we have thoroughly considered what our customers truly need and ruthlessly eliminated unnecessary costs, striking a balance of affordability, high quality, and high satisfaction.
As a result, we have earned high ratings on various review sites such as Google and Hot Pepper Beauty.
Consequently, about 80% of our first-time visitors become repeat customers.

Hot Pepper Beauty rating 4.57/5.00

Kirei Pass rating4.30/5.00

What is Rejuran Generic (Kiarareju)?
Put simply, Rejuran Generic (Kiarareju) is a preparation that injects the same main component—polynucleotide (PDRN)—as Rejuran.
Therefore, you can consider its effects to be the same as those of Rejuran.
On the other hand, because it is a later-developed preparation, research and development costs have been reduced, allowing it to be offered at a lower price than Rejuran.
Details of Rejuran Generic (Kiarareju)
Rejuran Generic (Kiarareju) is a preparation whose main component is salmon-derived polydeoxynucleotide (PDRN). In addition to polydeoxynucleotide, it contains hyaluronic acid and niacinamide, and it is also called a skin booster because it boosts the skin's inherent power. It is also sometimes referred to as a "salmon injection" because it uses salmon-derived polydeoxynucleotide.
When you hear "salmon-derived polydeoxynucleotide," some people may think of "Rejuran," known for its cell regeneration effect.
Rejuran is a preparation whose active ingredient is polydeoxynucleotide (PDRN) extracted from salmon DNA, which has the effect of enhancing the skin's self-regeneration power.
Polydeoxynucleotide (PDRN) has various effects, including increasing the production of growth factors, promoting capillary circulation, anti-inflammatory action, and DNA resynthesis.
Effects of Rejuran Generic (Kiarareju)
The effects of Rejuran Generic (Kiarareju) are basically the same as those of Rejuran.
- Improved skin texture
- Moisturizing
- Improved skin tone
- Improved skin elasticity
- Improvement of fine wrinkles
- Strengthened skin barrier function
Components of Rejuran Generic (Kiarareju)
- Polydeoxynucleotide: skin regeneration
- Hyaluronic acid: high moisturizing effect, long-lasting
- Niacinamide: brightening
Rejuran Generic (Kiarareju) contains the same components as Rejuran..
Hyaluronic acid is a component found in human skin and cartilage, with a high moisture-retention effect. It decreases with age. It is considered relatively safe, as it has the property of being absorbed into the body.
Niacinamide is a component recognized by the Ministry of Health, Labour and Welfare for its brightening, wrinkle-improving, and skin-roughness-improving effects.
Features of Smart Skin Clinic's Water Light Injection
At our clinic (Smart Skin Clinic), we inject Rejuran Generic (Kiarareju) using a Water Light Injection device.
Our clinic's Water Light Injection is performed with a strong commitment to our customers, so please take a look at the post below.
Treatment areas for Rejuran Generic (Kiarareju)
- Face (forehead, temples, nose, cheeks, fine lines, wrinkles)
- Neck
- Décolletage
- Backs of the hands
Rejuran Generic (Kiarareju) can be used on a wide range of areas, from the entire face to the neck and décolletage.
Pain during Rejuran Generic (Kiarareju) treatment
- A slight stinging pain when the needle is inserted
*Individual differences may occur; anesthesia is used
With Rejuran Generic (Kiarareju), pain can be reduced by performing the injection with suction.
The needles are ultra-fine, and 9 can be injected at once, reducing the number of times you need to be pricked.
Pain can also be further reduced by cooling the treatment area before the procedure or by using anesthesia. Note that at Smart Skin Clinic, the anesthesia fee is included in the price.
Duration of effects, longevity, and recommended maintenance frequency for Rejuran Generic (Kiarareju)
[When effects appear]
- Moisturizing and tone-up effects = immediately after treatment
- Skin regeneration effects = about 2 to 4 weeks after treatment
[Recommended number of treatments]
- 3 to 4 times at 2- to 4-week intervals (= 1 course)
[Duration of effects]
- Over 1 year
*After completing 1 course of treatment
[Recommended maintenance frequency]
- 1 course every 6 months to 1 year
Initially, you'll notice moisturizing and tone-up effects from the hyaluronic acid, and after 2 to 4 weeks the skin regeneration effects of polydeoxynucleotide will become apparent.
Like Rejuran, even a single treatment is effective, but repeated treatments make the effects more noticeable.
Recommended injection amount for Rejuran Generic (Kiarareju)
[Pattern 1] Light treatment for the forehead and areas below the nose → 3cc
[Pattern 2] Light treatment for areas below the nose, with more intensive treatment for areas above the nose → 4cc
[Pattern 3] Intensive treatment for the entire face, including areas below the nose → 6cc
If you're unsure which amount is right for your condition, please consult with us during the counseling session.
Downtime and risks of Rejuran Generic (Kiarareju)
The most concerning aspect of Rejuran Generic (Kiarareju) is likely its impact on daily life after the procedure.
Downtime for Rejuran Generic (Kiarareju)
[Duration]
- About 2 to 3 days
[Symptoms]
- Redness and bumpy swelling at the injection sites: disappears within 24 hours
- Stinging pain: a few days
- Bruising: gradually fades over 10 to 14 days
Pain and swelling can be relieved by cooling. It's best to wrap an ice pack in a clean cloth and apply it intermittently to the affected area.
Post-treatment care for Rejuran Generic (Kiarareju)
Please pay attention to the following points after the procedure:
- Skincare: possible immediately after treatment
- Shower: possible from the day of treatment
- Makeup: possible after about 24 hours
There is no significant impact on daily life after Rejuran Generic (Kiarareju) treatment. You can carry on with desk work as usual. If bruising occurs, it can be covered with concealer.
However, the skin is working to repair invisible wounds internally. Avoid activities that could hinder recovery, such as long baths, intense exercise, or massages that increase blood flow, as these may worsen downtime symptoms.
In addition to downtime symptoms, Rejuran Generic (Kiarareju) has the following potential side effects:
Risks of Rejuran Generic (Kiarareju)
In addition to downtime symptoms, Rejuran Generic (Kiarareju) has the following potential side effects:
- Pigmentation
- Infection
- Allergic reactions
After the procedure, avoid touching the treated area unnecessarily, as this can lead to pigmentation or infection. Also, since regenerating skin is prone to various skin troubles, including pigmentation, be sure to moisturize thoroughly and use UV protection.
While swelling, pain, and redness are similar to downtime symptoms and typically subside over time, a worsening of symptoms is an important sign of an allergic reaction. If you notice this, please consult the clinic immediately.
Note that Rejuran Generic (Kiarareju), like Rejuran, contains salmon-derived components, so it cannot be used by those with fish allergies.
Rejuran Generic (Kiarareju) treatment procedure
The treatment takes about 30 to 40 minutes excluding consultation, or about 60 minutes including anesthesia.
The treatment process is as follows:
STEP
You can easily make a reservation using your smartphone.
Our "smart" and easy check-in can be completed instantly using the clinic's IT system just by providing your name.
During the consultation, feel free to discuss any concerns you may have. Rest assured, there will be no pushy sales tactics.
We apply cream anesthesia, perform local anesthesia, and then proceed with the injection while communicating with you throughout the process.
We provide detailed explanations about caring for the treated area and precautions for daily life. We also recommend appropriate home care from a preventive and maintenance standpoint, including oral medications and skincare products that can help improve your concerns.
Japan's Lowest Standard Prices for Rejuran Generic (Kiarareju) (Recap)
Rejuran Generic (Kiarareju)
*A polynucleotide (PDRN) preparation similar to Rejuran
| 1 vial (2.2cc) | |
|---|---|
| 1 session | 24,800 yen |
| 3-session set | 68,400 yen (22,800 yen per session) |
| 4-session set | 79,200 yen (19,800 yen per session) |
| 2 vials (4.4cc) | |
|---|---|
| 1 session | 34,800 yen |
| 3-session set | 92,400 yen (30,800 yen per session) |
| 4-session set | 115,200 yen (28,800 yen per session) |
| 3 vials (6.6cc) | |
|---|---|
| First time | 36,800 yen |
| 1 session | 39,800 yen |
| 3-session set | 104,400 yen (34,800 yen per session) |
| 4-session set | 131,200 yen (32,800 yen per session) |
Need for anesthesia | High
The price includes all costs, including anesthesia.
This treatment is recommended with anesthesia, so it is standard to perform it with cream anesthesia and local anesthesia.
Details of Rejuran Generic (Kiarareju)
| Treatment time | About 30 to 40 minutes (excluding consultation) |
| Recommended number and frequency of treatments | We recommend 3 to 4 treatments at intervals of about 2 to 4 weeks. |
| Downtime | About 2 to 3 days |
| Treatment on the day of consultation | Possible |
| Makeup | Possible after about 24 hours |
| Skincare | Possible immediately after treatment |
| Shower | Possible from the day of treatment |
| Pain | A slight stinging pain when the needle is inserted |
Choose Smart Skin Clinic for Rejuran Generic (Kiarareju)
Smart Skin Clinic's Rejuran Generic (Kiarareju) uses 9 ultra-fine needles, with adjustable subcutaneous depth from 0.6 to 1.2mm and controllable injection amount.
Our pricing is transparent. We offer three unit sizes per vial—2.2cc, 4.4cc, and 6.6cc—with easy-to-try single-session fees and affordable 3-session and 4-session set prices to suit your needs and schedule.
If you have any questions, please feel free to ask during our free consultation. Our doctors will propose the best treatment for you.
Reference
Medical Supervision of This Page

Group Director, Smart Skin Clinic / Physician
Kota Ishii
Dr. Kota Ishii oversees the treatment policy across the entire Smart Skin Clinic group, tailored to each patient's skin condition. This page is supervised in accordance with our clinical policy.
Interview with Group Director Kota Ishii
Dr. Kota Ishii shares our approach to treatment. (Interview in Japanese.)
![Official] Smart Skin Clinic|Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)