Radical treatment of laugh lines with platelet injections (long-term duration of over 5 years)|Smart Skin Clinic



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↑This effect is achieved with injections alone and lasts about 5 years!
For a limited time, platelet injections for all areas 20% off
"I just want to get rid of my nasolabial folds."
"I've been comparing options for my nasolabial folds — hyaluronic acid injections, facelifts, thread lifts — but I'm afraid of surgery. Isn't there a way to get a natural-looking result?"
Hello, I'm a physician at Smart Skin Clinic, a cosmetic dermatology clinic. Do any of these questions or concerns sound familiar?
In this article, I will provide an easy-to-understand explanation from the perspective of the director of Smart Skin Clinic, which specializes in injection treatments and has performed over 24,000 procedures.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Do you have any of these concerns?
Ugh… it got deeper again…
Nasolabial folds that grow deeper as we age.
- Nasolabial folds so pronounced you're afraid to smile
- Sagging around the mouth that has crept up on you before you knew it
It really shakes your confidence when someone points it out…
What is different from my skin back in my teens?
The difference is…
The collagen and elastin that kept your skin looking beautiful have decreased with age.
This is one of the causes of nasolabial folds.
That said,
we don't really recommend conventional hyaluronic acid injections or facelifts…
Risks of hyaluronic acid injections (cross-linked type)
- There is a risk of blood clots
- Clots form inside the blood vessels and block the flow
- When this happens, it can lead to serious conditions such as heart attack and stroke
- They give an immediate volumizing effect, but are absorbed within 6–12 months
- They can feel off, and a lingering sense of a foreign object may remain
- Overdoing hyaluronic acid injections carries a risk of an unnatural look
Risks of a facelift
- There is a risk of infection associated with surgery
- There are risks associated with anesthesia
- Long downtime (around 1–2 weeks)
- It may leave scars for life
To you, who matter to us
Procedures that carry high risk and burden,
we do not recommend.
So, what should you do?
Not to worry.
- Low risk of blood clots
- No sensation of a foreign object
Let us introduce a new treatment. It is…
Platelet injections into the nasolabial folds.
What are platelet injections?
Platelet injections are a treatment that uses components drawn from your own blood to plump up the skin.
The blood contains tiny substances called "platelets." These platelets have the ability to heal wounds and generate new substances. In a platelet injection, a small amount of blood is first drawn from your arm. The platelets alone are then extracted and concentrated from that blood and injected into your skin.
The injected platelets begin to work within the skin, increasing collagen and elastin—the components that plump the skin. This can help improve wrinkles and sagging and bring the skin closer to a youthful appearance.
Before/After of our platelet injections




Three features of platelet injections
1. Long-term results and cost performance
The effecttypically lasts 5 years or more. Because the results of a single treatment last for an extended period, it offers excellent cost performance.
2. Natural rejuvenation effect
Because it uses components derived from your own body, the result looks natural. The risk of the lingering unnaturalness sometimes seen with hyaluronic acid injections is small.
3. Customized treatment
At our clinic, we adjust the concentration and injection volume to suit each patient’s skin condition and goals, and design the injections on an individual basis.
How platelet injections work: why are they effective for nasolabial folds?
The main reasons platelet injections are effective for nasolabial folds are as follows:Four Mechanismsis due to
1. Promoting Collagen Production
Platelet injections promote collagen production, improving the skin's firmness and elasticity. This helps improve the sagging that causes nasolabial folds.
2. Promoting elastin production
Platelet injections also promote elastin production. Elastin is an important protein that maintains skin elasticity, and increasing it makes the skin around the nasolabial folds more supple.
3. Improving skin thickness
The action of platelet injections thickens the dermal layer of the skin. This makes nasolabial folds less noticeable and gives an overall more youthful impression.
4. Boosting circulation
Platelet injections promote the formation of new blood vessels. Circulation improves and skin metabolism is activated. This improves the overall skin quality around the nasolabial folds.
The combined action of these mechanisms helps improve the appearance of nasolabial folds.
Platelet injections are recommended for
Those concerned about nasolabial folds
Those who have noticed more visible expression lines
Those concerned about sagging cheeks
Those who want to restore firmness
and elasticity to the skin overall
Those who want a natural-looking result
Strengths of Smart Skin Clinic's platelet injections
1. Specialists in Injectable Treatments
・Optimal injections backed by extensive experience and advanced technique
・A proprietary injection technique that minimizes pain
Treatment customized for each patient
2. Anti-aging experts
The director is a board-certified specialist of the Japanese Society of Anti-Aging Medicine
Smart Skin Clinic platelet injection pricing
Typical pricing in Tokyo
The typical price of platelet injections in Tokyo isAround 300,000–400,000 yen(as of August 1, 2024).
Because this procedure cannot be performed without special equipment and can only be carried out at facilities certified by the Ministry of Health, Labour and Welfare, it is more expensive than ordinary hyaluronic acid injections and considerably less expensive than a surgical facelift.
Smart Skin Clinic's platelet injection price list
Our clinic is certified by the Ministry of Health, Labour and Welfare to perform platelet injections
Because this treatment lasts about 5 years, when you factor in the duration, its pricing can be considered more economical than hyaluronic acid injections and the like.
For a limited time, platelet injections for all areas 20% off
| Menu | Regular Price | Limited-time discount through August 31 (20% off) |
| Once | 166,400 yen | |
| Monitor 1 session | 142,400 yen | |
| Second area (face) | ¥133,120 | |
| Monitor Second Area (Face) | ¥109,120 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Prices are shown all-inclusive, covering consultation and needle fees.
There is no separate upselling on the day.
Monitor Requirements
①Intended Use| We may publish the photos on our website, Instagram, and similar media with the eye area concealed, or show them to other patients as treatment examples [please picture typical case photos].
②Procedure|You pay the regular price at your first visit, and we refund the difference (between the regular price and the monitor price) at the time of the monitor photo shoot (approximately one month after treatment as a guide).
Why we can deliver both "high quality" and "some of the lowest prices in the nation"The reasons we can achieve this
In fact, more than 90% of aesthetic clinics carry too many unnecessary costs to offer their patients the best possible price.
Guided by this awareness of the problem, we created an aesthetic clinic completely unlike the conventional norm.
(1) Areas with low rent
(2) Cutting back on lavish interiors
(3) Cutting back on excess staffing
(4) Cutting back on excessive advertising spend
This is how we deliver something other clinics can't match: the "High-quality platelet injectionsoffered at one of the lowest prices nationwide" we're able to achieve.
Smart Skin Clinic consistently earns high ratings in reviews on Google, Hot Pepper, KireiPass, and more.
At Smart Skin Clinic, we think carefully about what our patients truly need and thoroughly cut out unnecessary costs, allowing us to deliver affordability, high quality, and high satisfaction all at once.
As a result,we earn high ratings across a variety of review sites, including Google and Hot Pepper Beauty.we have earned.
As a result, about 80% of those who visit us once return for repeat treatment.
Google review rating 4.5/5.0 (97 reviews)

Hot Pepper Beauty rating 4.57/5.00

KireiPass rating4.30/5.00

Kumapon rating4.71/5.00

Gangnam Unni rating9.3/10.0

The platelet injection procedure
- Blood draw: A small amount of blood is drawn from the patient's arm
- Extracting components from the blood: a special centrifuge is used to extract the skin-plumping components
- Adding nutrients: nutritional components are added to the extracted blood components
- Injection design: we create the design best suited to your concerns
- Injection: a fine needle is used to inject the skin around the nasolabial folds
The needles used are extremely fine, minimizing pain. Anesthetic cream can also be used if needed.
Precautions and Side Effects
Platelet injections are relatively safe, but the following temporary side effects may occur:
・Mild swelling or bruising at the injection site
・Temporary pain or discomfort
In rare cases, infection or an inflammatory reaction may occur. At our clinic, strict hygiene protocols and skilled technique help minimize these risks.
FAQ
Q1: Are platelet injections painful?
A1: Because we use an extremely fine needle and can apply anesthetic cream if needed, most patients experience only mild discomfort.
Q2: When can I expect to notice results?
A2: Results vary by individual, but most patients begin to notice a gradual effect from around 2 to 4 weeks. The full effect often appears after 3 to 6 months.
Q3: How many sessions are typically needed?
A3: One treatment typically lasts more than 5 years.
Summary
Platelet injections are an effective treatment for improving nasolabial folds. Because they use components derived from your own body, they are safe and known for their natural-looking results. They can address even deeply etched nasolabial folds and can offer long-lasting effects.
At Smart Skin Clinic, we draw on our expertise in injectable treatments and anti-aging to provide optimal platelet injections.
Since results and duration vary by individual, we recommend a personal consultation for more detail. Let's find the nasolabial fold treatment that's right for you.
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.
We aim to "make aesthetic medicine more accessible" for you.
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
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