I wonder what Dermapen x Exosomes are and how they work?" 'I'm interested in getting the Dermapen x Exosome, and I'd like to get it at a place that's a little less expensive.'
Do you have any of these questions or concerns?
In this article,Ministry of Health, Labour and WelfareThe following is an easy-to-understand explanation from a professional standpoint by a cosmetic dermatology clinic that is a member of the "Aesthetic Dermatology Clinic". (* Type II and Type III Regenerative Medicine Provisioning Plans Accreditation Number: NA8230001)
*If you would like to know the rates, you can jump to the appropriate section from the table of contents below.
TOC
dermapenWhat is 4
Dermapen is a skin treatment device. The tip of the device is equipped with multiple needles thinner than a hair. By inserting these ultra-fine needles into the skin, a process called "wound healing mechanism" occurs inside the skin, resulting in the improvement of skin texture.
What is the wound healing mechanism?
Humans have the ability to repair cells naturally, and minor wounds (wounds) will heal spontaneously. The reaction of cells to return to their original state when they are damaged is called wound healing. Many of you may have experienced the feeling of smooth skin after scabbing over a wound, which is also called wound healing.
It also acts on the epidermis, the shallow layer of the skin, as well as the dermis, the deeper layer of the skin, to normalize skin turnover, which helps to prevent keratin clogging and blemishes.
Although a dermapen can be used by itself, in most cases, an "induction solution" is used at the same time. This is because the dermapen makes a hole in the skin, and the introduction solution allows the drug to penetrate deep into the skin. (Normally, the skin's surface barrier prevents the drug from penetrating deep into the skin.)
What is an exosome?
Exosomes (also called exosomes) are granule-like substances with a diameter of 50-150 nm (nanometers: one billionth of a meter) that are secreted by cells. Their surfaces contain lipids and proteins derived from cell membranes, while their interiors contain nucleic acids (microRNA, messenger RNA, DNA, etc.), proteins, and other intracellular substances.
Exosomes secreted by cells are not only found between cells, but are also present in body fluids (blood, spinal fluid, urine, etc.) and circulate throughout the body. One important function of exosomes that has been highlighted is that they are used to transmit information between cells. As mentioned above, exosomes contain nucleic acids, proteins, and other substances inside them. Since it has been reported that secreted cellular nucleic acids (microRNAs and messenger RNAs) are transmitted to receiving cells via exosomes and function, exosomes are thought to work as communication tools between cells.
As described here, exosomes will be substances in the body that function as "information transmission tools between cells".
The effects of exosomes have been found to include cell activation, angiogenesis, and suppression of inflammation (anti-inflammatory action), resulting in skin beautification, anti-aging, treatment and prevention of diseases, and relief of fatigue and insomnia.
The Dermapen 4 x Exosome allows exosomes with these effects to penetrate directly into the skin.
What is Dermapen 4 x Exosome?
This treatment improves skin texture by creating microscopic holes in the skin with a dermapen4 and introducing exosomes directly into the skin through these holes.
Recommended for the following problems
To improve acne scars (craters, hyperpigmentation)
I want my skin to look firm and luminous.
Reduce the appearance of pores
I want to have beautiful skin like Koreans.
Effect
Effect
Enhances skin's ability to regenerate
Improvement of skin quality
Improvement of pore opening and plugging of horny plugs
Improvement of acne scars (craters, hyperpigmentation)
Promotes natural cell repair and more youthful skin
Renew skin and revitalize its functions
Although Dermapen4 by itself has a skin rejuvenation effect,The introduction of exosomes further enhances this effect.
Exosomes promote wound healing through TGF- β receptor inhibition, which speeds wound closure and reduces scar healing/scar formation while regulating collagen fiber distribution and supporting regeneration of appendages (hair, sebaceous glands, nerves, blood vessels and other skin appendages).
In the following paper,Dermapen x Exosome Introductory Solution has proven to be effective.
The contents of this page include "Comparative experiments between exosome-containing solutions (HACS) and microneedles (dermapen) in combination in patients with aging skin.
Simply put, the study found that "a comparison of wrinkles, elasticity, moisture, and pigmentation between the application of exosomes (HACS) on one side of the same person's face and the application of saline solution on the opposite side showed greater improvement on the exosome (HACS) side.
Global Aesthetic Improvement Scale scores were significantly higher on the exosome-containing solution treated side than on the control side (p = 0.005), including PRIMOS Premium, Cutometer MPA 580, Corneometer CM 825, Mark-Vu Objective measurements with various instruments confirmed a clinically significant improvement in skin wrinkling, elasticity, moisture, and pigmentation on the HACS-treated side over the control side. Results of histopathological evaluation were consistent with clinical findings. No serious adverse events were observed.
Recommended number/frequency of treatments｜How many times should I have the treatment?
This item is a question that is often asked during actual counseling, so we will explain it in the form that we actually tell you at the clinic.
How many Dermapen x Exosomes is it best to undergo?"
About 5 to 10 timesI think it would be a good idea to take it.
How long is the best interval between visits?"
1 month intervalis a good idea.
The reason why we do not use an assertive tone is that the effects of cosmetic dermatology procedures vary from person to person, and we are providing information neutrally based on the methods recommended by cosmetic dermatologists in general and the methods recommended by manufacturers. Although we do not make any assurances, we basically recommend that you receive the above-mentioned number of treatments and frequency.
Advantages/Disadvantages
Advantages
Skin texture improvement effect can be obtained.
Higher effect in the same amount of time compared to dermapen alone
Reduced downtime due to the anti-inflammatory action of exosomes compared to dermapen alone
When compared to exosome infusion, it has a higher effect on the skin because of its concentrated approach to the skin.
Demerit
Pain from dermapen.
Some downtime (reduced compared to dermapen alone due to the anti-inflammatory effects of exosomes)
More expensive than dermapen alone
Smart Skin Clinic's Dermapen x ExosomeFeatures of
Adopt the official exosome formulation from DermapenWorld, a manufacturer of dermapen devices
There are many different types of exosome induction solutions, but we haveWe use MG-EXO-SKIN™, the official exosome formulation from the company that manufactures the dermapen device.
Since it is an official formulation of Dermapen, it can be used with Dermapen without any problem.
With the ability to attach approximately 7,000 exosomes to the tip of a single 33G Dermapen 4™ needle, the Dermapen is an efficient device that delivers exosomes to the skin without compromising them.
Six active ingredients other than exosomes in MG-EXO-SKIN™.
Our exosome induction solution contains not only exosomes but also six other active ingredients. Each of these ingredients and their actions are listed below.
(1) HylaFuse™. Hyaluronic acid of three different molecular weights
- Penetration enhancers to increase delivery of active ingredients - High moisturizing power
2) Calphasomes™. Calcium phosphate compounds - Penetration enhancers that stimulate lamellar granules and fibroblasts to increase ceramide and collagen synthesis.
3) Ascorbyl phosphate Na Stabilized Vitamin C - A versatile redox agent that removes active oxygen species while soothing pigmentation.
Zinc PCA zinc salt Supports wound healing by reducing inflammation and re-epithelialization.
(5) Pan tenor Pro-vitamin B5 - Wound-healing agent with high wetting effect. - Related to tissue repair and regeneration.
(6) Aloe Vera Antioxidant plant-derived ingredients - Plant-derived ingredients with anti-inflammatory and antioxidant properties. Rich in bioflavonoids, polyphenols, and tannins with healing properties.
More than 200 cases of Dermapen 4 x Exosome
We offer Dermapen 4 as a skin texture improvement procedure. The number of cases in which Dermapen 4 was used with Exosome induction solution is over 200.
*For the period June 23, 2023 to October 31, 2024.
Appropriate dermapen needle depth is set after examination by the physician
Dermapen4 allows you to adjust the depth of the needle. Deeper is not necessarily more effective; there is an appropriate depth depending on your concerns and skin area.
The doctor will perform the procedure after examining you and determining the appropriate depth for you.
See also the following article on the proper needle depth for dermapen.
There are other procedures using exosomes besides the dermapen.
Other than direct introduction into the skin, the method is administered intravenouslyThere is a This procedure is called exosome infusion.
Although Dermapen x Exosome is higher in direct effect on the skin, it can provide a variety of other benefits when administered intravenously into the body.
Click here for more information on Exosome infusion.
Basically, it is possible to perform the procedure unless you have some serious illness or inflammation in the area to be treated.
The following information is provided for reference only, as we are obliged to include it to inform "those who are not eligible for the treatment".
Pregnant or nursing mothers
Persons with abnormal immune function or with a history of such abnormality, and persons receiving immunosuppressive therapy.
Those prone to keloid formation, hypertrophic scars and hyperpigmentation
Those with bleeding tendency or using non-steroidal anti-inflammatory analgesics such as aspirin or anticoagulants such as warfarin
Excessive sunburn, eczema, dermatitis, highly inflamed acne, or scabs at the dermapen x exosome treatment site
DowntimeRisks/side effects
Dermapen x Exosome has the following downtime symptoms, risks and side effects
Redness and swelling [will always occur]. After the procedure, especially during the first 24 to 48 hours, the skin may become red and swollen. This is normal and is a natural reaction to the procedure. This condition is temporary and usually settles down in a few days.
Risk of infection [rare The dermapen leaves microscopic holes in the face, and there is a risk of infection if bacteria enter through these holes. This will not happen in most cases as long as the patient avoids touching the face too much after the procedure and avoiding unclean conditions.
skin eruptions To stimulate the production of new skin cells, the old skin may peel off naturally. This is part of the recovery process and is a normal process. When peeling occurs, it is important to keep the skin properly moisturized and avoid direct sunlight.
Pain and discomfort During the procedure, some pain may be felt, but this is felt differently by each person. The same is true for discomfort after the procedure, which usually eases quickly.
Excessive inflammatory response Individuals with sensitive skin or certain skin conditions may experience excessive reactions. For this reason, we will provide a detailed consultation prior to the procedure to accurately assess your skin condition.
If you have any concerns or questions, please feel free to contact us, no matter how small.
Post-treatment precautions/aftercare
The downtime period should include the following
Avoid highly irritating skin care products during the downtime period. Avoid using products containing hydroquinone and retinol for about 2 weeks.
Avoid strenuous exercise, saunas, and prolonged sun exposure.
Keep the treatment area clean and do not forcefully touch or rub the area.
All prices include tax. This special first-time price cannot be used in conjunction with other campaigns.
The above rates areTotal cost including all consultation and anesthesia feesWe will not be upselling on the day of the event. There will be no upselling on the day of the event.
Dermapen + Exosome" and "Exosome infusion": Smart Skin Premium Program
First time special price
60,800 yen ⇒ 39,800 yen
Once
60,800 yen
3 sets
166,500 yen(1 time 55,500 yen)
Set of 5 times
249,800 yen(1 time 49,960 yen)
Set of 7 times
319,800 yen(1 time 45,685 yen)
Set of 10
397,500 yen (One time 39,750 yen)
All prices include tax *This special first time price cannot be combined with other campaigns *This clinic is a free clinic and insurance is not covered.
Flow of treatment
STEP
Reservation
You can easily make reservations with your mobile phone.
It's "smart" and easy: just scan the QR code at the reception desk.
STEP
Counseling and medical examination
In counseling. Please feel free to discuss any concerns you may have. Please be assured that there is no pushy sales.
STEP
Dermapen 4 x Exosome treatment
After anesthesia is administered, the patient's skin is set up accordingly and the procedure is performed.
STEP
After-sales service
We will explain in detail about the care of the treated area and precautions for daily life. We also suggest appropriate home care from the viewpoint of prevention and maintenance, such as oral medicines and skin care cosmetics that can be expected to improve your problems.
STEP
Returning home
FAQ
How often and how many times should I take the course?
Dr. Smaski.
Although a single session is effective, it is recommended to have 4-5 sessions every 4-6 weeks.
Can I have other treatments at the same time?
Dr. Smaski.
Basically, avoid other procedures on the same day. Our clinic also offers laser and chemical peelings, but we ask that they not be used together.
4 to 6 times in total, about once every 4 to 6 weeks
Down time
About 2 to 3 days
Treatment on the day of counseling
Possible
Make
12 hours recommended
Skin care
Recommend not using face wash, lotion, emulsion, etc. for 12 hours
Shower
Allow 12 hours for the face, from the neck down can be done on the same day.
*There are individual differences.
Smart Skin Clinic
Smart Skin Clinic
The concept of the clinic is to "make cosmetic medicine more accessible and smart.
The clinic's concept is to make cosmetic medicine more accessible and smart.
The clinic has eliminated gaudy interior design to reduce interior costs, and instead of introducing equipment in the dark, it carefully selects the equipment it needs and reduces the cost of the equipment.
We aim to "make cosmetic medicine more accessible to as many people as possible.
Address: 8F EX Kanda Nishiki-cho Building, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo Specialty: Cosmetic Dermatology (aesthetic dermatology, medical hair removal, medical slimming)
Address: 8F EX Kanda Nishiki-cho Building, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo Specialty: Cosmetic Dermatology (aesthetic dermatology, medical hair removal, medical slimming)
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of the Smart Skin Clinic supervising physicians.
This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.
This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.
Dr. Smaski.