PROFHILO BODY | A Doctor Explains the Effects, Treatment Details, and Drawbacks

*Number of cases | During the period from September 1, 2023 to March 31, 2024
“I wonder what Profhilo Body is.”
“I know Profhilo, but what is Profhilo Body?”
“I'd like to try Profhilo Body.”
Hello, I am a doctor at Smart Skin Clinic, an aesthetic dermatology clinic.
Do you have any of these questions or concerns?
Profhilo is hugely popular, and a body-specific Profhilo has recently become available, so we'll explain in clear terms, from an expert's perspective, what kind of formulation it is.
*You can jump to the pricing and other details from the table of contents below.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What is Profhilo Body?
Profhilo is an injectable treatment to improve skin elasticity and firmness on various areas of the body.
Profhilo is a product developed by the Italian company IBSA Derma, known for using highly concentrated hyaluronic acid to create a natural lifting effect on the face and elsewhere.
Profhilo Body is the body version, using the same technology to benefit the skin on the body as well.
Overview and effects of Profhilo
What is Profhilo?
Profhilo is an injectable treatment containing a high concentration of hyaluronic acid that promotes skin regeneration and provides a natural lifting effect. Unlike conventional fillers and botulinum toxin, Profhilo works in the deeper layers of the skin to improve skin texture by stimulating the production of collagen and elastin.
Effects of Profhilo
- Improved skin firmness and elasticity: Replenishes moisture in the skin and enhances its elasticity.
- Improvement of wrinkles and sagging: Because it works into the deeper layers of the skin, it effectively improves wrinkles and sagging.
- Increased collagen and elastin: This strengthens the skin's structure.
Effects of Profhilo Body
- Tightening of body lines: Injecting into specific areas can help tighten the silhouette of the whole body.
- Improved skin firmness and elasticity: Profhilo Body uses the power of hyaluronic acid to replenish moisture in the deeper layers of the skin, enhancing skin firmness and elasticity.
- Improvement of wrinkles and sagging: Because it works into the deeper layers of the skin, it effectively improves wrinkles and sagging.
- Increased collagen and elastin: Promotes the production of collagen and elastin, strengthening the skin's structure.
- Improvement of a décolletage that has become thin and aged: Improves aging of the décolletage caused by weight loss.
- Improvement of fine creases on the abdomen after childbirth or weight loss: Smooths out fine creases on the abdomen after childbirth or weight loss.
- Improvement of fine lines on the upper arms, above the elbows, and above the knees: Reduces fine lines in these areas.
Treatment details
Treatment area
Profhilo Body can be performed essentially anywhere on the body. Common areas include the following:
- Décolleté
- Backs of the hands and fingers
- Abdomen
- Above the elbows
- Above the knees
- Thighs
What's in the Profhilo Body kit

The Profhilo Body kit consists of one kit with the following contents:
- Profhilo 3 cc x 2 syringes(usually 2 cc for the face)
- Post-treatment tape: Applied immediately after injection to protect the injection site. The tape is left on for 30 minutes to 3 hours.
- Body cream for aftercare: Protects the skin after treatment and supports recovery.
Treatment Method
- Treatment area and injection amount: Typically, one syringe of 3 cc (0.3 cc at a time) is injected across 10 sites. As a guide, 3 cc is used for the abdomen (upper or lower), and 6 cc across 20 sites for both legs, both arms, and the upper and lower abdomen.
- Injection sites: Injected into the shallow layer of the skin, from the dermis to just beneath the dermis.
- Treatment Time: The procedure usually takes about 30–45 minutes.
Aftercare
- Whether there is downtime: Mild swelling and redness may occur, but usually disappear within a few days.
- Key points for aftercare: After treatment, it is recommended to use specific skincare products and keep the skin moisturized. The second treatment is 4 weeks later, and until then, you care for the skin with body cream.

Advantages and disadvantages
Benefits
- Natural finish: Because it promotes the skin's natural regenerative process, the results are very natural.
- Both immediate and long-lasting: The effect can be felt soon after treatment and lasts for several months.
Drawbacks
- Risk of pain and swelling: Temporary pain and swelling may occur at the injection sites.
- Cost: Because it is a high-quality treatment, it can be costly.
The safety of Profhilo Body
The ingredients used and their safety:
The hyaluronic acid used in Profhilo Body is highly biocompatible and has a proven safety record.
Side effects and risks:
Common side effects include swelling, redness, and mild pain at the injection sites. Major risks are very rare.
Pricing
Profhilo has standardized injection sites and volumes*, and one syringe (3 cc to 6 cc) is used per treatment. In other words, the amount of Profhilo used per treatment is basically the same at any clinic, making it easy to compare treatment details and prices.
*There may be slight individual differences, and customized treatment is sometimes provided.
*Treatable areas
Anywhere on the body except the face
e.g., décolleté, backs of the hands, abdomen (upper and lower), above the elbows, fingers, above the knees, thighs, etc.
*Required dosage
3cc per area is the guideline. When treating both left and right, or both the upper and lower abdomen, a total of 6cc per session is recommended.
| 1 session (3cc) | 59,800 yen |
| 2 sessions (3cc × 2) [Includes 1 bottle of dedicated body cream] | 109,600 yen (54,800 yen per session) |
| 4 sessions (3cc × 4) [Includes 2 bottles of dedicated body cream] | 194,200 yen (48,500 yen per session) |
| [Monitor price] 2 sessions (3cc × 2) [Includes 1 bottle of dedicated body cream] | 99,600 yen (49,800 yen per session) |
| [Monitor price] 4 sessions (3cc × 4) [Includes 2 bottles of dedicated body cream] | 184,200 yen (46,000 yen per session) |
Need for anesthesia | Low
This treatment generally does not require anesthesia.
We would like to keep this pricing, so if you would like numbing cream we charge[5,500 yen (tax included) per session]for it. (*This is because anesthesia adds about 20 minutes to the treatment time.)
Monitor Requirements
①Intended Use|Your photos may be published on our website, Instagram, and other media with your face concealed, or shown to other patients as treatment examples [please picture the kind of general case-study photo you often see].
②Procedure|You pay the regular price at your first visit, and we refund the difference (between the regular price and the monitor price) at the time of the monitor photo shoot (3 to 7 days after the final treatment).
Things worth confirming before having the treatment
Recommended for people who:
・want to improve a décolletage that has become thin and aged
・want to improve the rough, bony look of the backs of the hands
・want to improve wrinkles on the abdomen after childbirth or weight loss
・want to improve fine lines on the upper arms, above the elbows, and above the knees
Those who are not eligible for the treatment
Those who are pregnant or breastfeeding
Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy
Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders
Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin
Those with excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Profhilo injection site
FAQ
- How often should I have the treatment?
-
Usually, 2 to 3 treatments are recommended. To maintain the effect, regular maintenance is needed.
- How long do the effects last?
-
The effect after treatment lasts 6–12 months. There are individual differences, but the effect can be prolonged with regular maintenance.
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
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