![Official] Smart Skin Clinic｜Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)
Personalized PRP Injection for Nasolabial Folds
Personalized PRP Injection
Regenerative Medicine Provision PlanSubmitting Facilitynote 1
People in their 50s and 60sMany Patients Visited Our Clinic
Number of PRP Treatment CasesMore than 1,000 cases*2
*1 Type II and Type III Regenerative Medicine Provision Plans: Certification No.: NA8230001
*2 Jimbocho Clinic (Period: June 2023 – March 14, 2026) and Yokohama Clinic (Period: July 2025 – March 14, 2026)
*Please note that the treatments listed on this page are private, out-of-pocket services and are not covered by public health insurance. Results may vary from person to person.
| Menu | Prices (including tax) |
| Personalized PRP Injection (1 session) | 208,000 yen |
| On the same day, for the second and subsequent areas (face), per area | 166,400 yen |
*Please note that our clinic provides private medical care, and public health insurance does not apply.
*Includes consultation and acupuncture needle fees. There are no additional charges on the day of your visit.
Nasolabial foldsAre you curious about this?
As we get olderThose nasolabial folds are starting to bother me.
Without surgery, using components derived from your own bloodTreating nasolabial foldsThere is a treatment.
- Without using a scalpel,Aiming for a Natural Look
- Generally, one treatment session(The duration may vary from person to person.)
- Downtime is short, andYou can wear makeup starting the next day
- Components derived from your own bloodI'll use it
In this article,Has submitted a Regenerative Medicine Service Provision PlanSmart Skin Clinic, a cosmetic dermatology clinic,From a professional standpointI'll explain it in simple terms.
(*Type II and Type III Regenerative Medicine Provision Plans) Certification Number: NA8230001)
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
For those with these concerns
- My nasolabial folds have deepened, andIt makes me look a lot older all of a sudden…
- A natural finishI hope to
- Surgery and major medical treatments areI want to avoid that…
- Since I don't want anyone to find out,I prefer treatments with minimal downtime.
- Want a treatment with long-lasting results
For those of you who are facing these kinds of challenges,Our clinic's personalized PRP injectionsIt has been selected.
Case Photos (Before/After)
Before: Before Treatment
After: Following the completion of one treatment session
| Treatment period and number of sessions | Typically, only one treatment session is required*In cases where the results are insufficient, additional treatments may be performed. |
|---|---|
| Treatment price | 166,400–208,000 yen (tax included)*1: 208,000 yen per area; 166,400 yen per area for the second and subsequent areas on the same day. As this is a private medical service, public health insurance does not apply. |
- Mild redness, swelling, or bruising may occur after the injection, but these symptoms usually subside on their own within a few days.
- You may experience mild pain or a sensation of a lump at the injection site, but these symptoms are usually temporary and can be alleviated with proper aftercare.
- In very rare cases, allergic reactions or the formation of tumors at the treatment site have been reported. If you experience any concerning symptoms, a doctor will examine you directly and provide appropriate care.
- Results vary from person to person, and we cannot guarantee the same outcome for every patient.
Number of PRP Treatment Cases
1,000and more
*Jimbocho Branch (Eligibility Period: June 2023 – March 14, 2026) and Yokohama Branch (Eligibility Period: July 2025 – March 14, 2026)
What Is Personalized PRP Injection?
PRP (platelet-rich plasma) is,Extracted from your own blood,This ingredient is rich in growth factors.
Focusing on the skin's own regenerative power,We will address the nasolabial folds.
STEP 01
Blood Draw
We will draw a small amount of blood. The procedure is the same as for a regular blood test.
STEP 02
Purification
We purify PRP to a high concentration and blend it with growth factors (FGF).
STEP 03
Injection
Inject the appropriate amount into the appropriate layer.
PRP contains platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and other factors that promote collagen production, improve blood flow, and facilitate cell repair.
Tailored to each individual,Four Points of Personalization
Rather than relying solely on a doctor's judgment,In every step of the processBacked by clinical data.
Tailored to each individualWe design it.
Personalized Diagnosis
Based on case dataAnalyze body structure and skin condition.Whether PRP is appropriateWe'll check and then make a proposal.
Personalized Purification
Based on numerous clinical results,We have derived,Our clinic’s proprietary purification protocol.
Personalized Design
Aiming for a Natural LookAfter considering the location and quantity,First, create the design plan, then proceed with the treatment.
Personalized Injection
Across the entire groupOver 24,000 injections performed annually.The right amount to the right layer,We'll deliver it right on target.
Difference from hyaluronic acid injections
| Comparison point | Personalized PRP Injection | Hyaluronic acid injections |
|---|---|---|
| Treatment details | Injects PRP extracted from your own blood to promote skin regeneration | Injects synthetic hyaluronic acid to add volume |
| Results | Aiming for a Natural Look | The final result varies depending on the amount injected. |
| The Concept of Sustainability | Due to organizational changes (the timeframe may vary by individual) | Absorbed within roughly 6 months to a year |
| Downtime | Short-term (you can resume your normal daily activities the same day) | May cause bruising or swelling |
| Materials Used | Using components derived from your own blood | Use a formulation that is absorbed by the body |
| Treatment Time | Approx. 20 minutes | Approx. 15-30 min. |
Treatment details
Results
The Concept of Sustainability
Downtime
Materials Used
Treatment Time
Which option is best for you depends on the condition of your face and your preferences. I will explain this to you after your consultation.
Causes of nasolabial folds and how PRP works
The causes of nasolabial folds are,It's not just sagging.
Loss of skin elasticity, fat atrophy,Since this results from cumulative volume loss,A comprehensive approach isIt is considered necessary.
Three actions of PRP
Features of Personalized PRP Injection
(Results may vary.)
Personalized treatment
Submitting Facility
Pricing
| Menu | Prices (including tax) |
| Personalized PRP Injection (1 session) | 208,000 yen |
| On the same day, for the second and subsequent areas (face), per area | 166,400 yen |
*Please note that our clinic provides private medical care, and public health insurance does not apply.
*Includes consultation and acupuncture needle fees. There are no additional charges on the day of your visit.
Prices are shown all-inclusive, covering consultation and needle fees.
Information on Private Medical Services
- Because it is: The treatments described on this page are private medical services not covered by public health insurance. You are responsible for the full cost.
- Cost: As shown in the price list above (all prices include tax). The fee includes the consultation fee, and there are no additional charges other than those listed.
- Treatment Duration and Number of Sessions: Typically, one treatment session (treatment time: approximately 20 minutes; plus approximately 1 hour of waiting time for PRP preparation). Additional treatments may be performed if the results are insufficient.
- Main risks and side effects: Mild redness, swelling, or bruising may occur after the procedure (these symptoms usually subside within a few days). You may experience mild pain or a sensation of a lump at the injection site. In extremely rare cases, allergic reactions or tumor formation at the treatment site have been reported. Additionally, the growth factor (bFGF) preparation used in this procedure is off-label for cosmetic purposes and is not covered by the Pharmaceutical Side Effect Victim Relief System.
- Regarding effectiveness: Results and duration may vary from person to person, and our clinic does not guarantee any specific results.
- Regenerative Medicine Provision Plan: Type II and Type III Regenerative Medicine Provision Plans Submitted (Certification Number: NA8230001)
- Contact Us: Smart Skin Clinic TEL 050-1720-6230
First of all,You're welcome to just come in for a free consultation.
"I'm nervous about deciding on a treatment right away..."That's what most people say.
Counseling at our clinic is,This is not intended to be a treatment.
- "Just listen to what I have to say,We also welcome you to “take your time to consider it at home.”
- Includes a doctor's consultation.Whether it applies or not, andAll the way through to assessing the final resultI can confirm that
- All-inclusive, covering consultation fees and other costsTransparent pricing.There are no additional charges on the day of the event.
Reception Hours: Weekdays 11:00 a.m.–8:00 p.m. / Saturdays and Sundays 10:00 a.m.–7:00 p.m.
Treatment Flow
(Waiting time: about 1 hour) From the customer's own blood,At the on-site processing facilityWe perform PRP extraction and processing.This is a delicate process, andSince this will take some time,It will take about an hour for our customersYou will need to wait.(You are free to go out.)
If you have any questions, please consult directly with a physician
To help ease any concerns as much as possible, at our clinic
During a free consultation, a doctor will speak with you directlyHere is my answer.
Whether or not to undergo the treatment depends on,
Please take your time to consider it after that.
We’re happy to provide consultations only as well.
Treatment details
・Those who are pregnant or breastfeeding (please consult your doctor before treatment)
You may experience mild pain or a sensation of a lump at the injection site, but these symptoms are usually temporary and can be alleviated with proper aftercare.
In very rare cases, allergic reactions or the formation of tumors at the treatment site have been reported. If you experience any concerning symptoms, a doctor will examine you directly and provide appropriate care.
Results vary from person to person, and the same outcome cannot be guaranteed for every patient.
*The growth factor (bFGF) preparation used in this procedure is a pharmaceutical product approved in Japan that is being used off-label for cosmetic purposes; therefore, it is not covered by the Pharmaceutical Side Effect Relief System. A physician will explain the risks associated with off-label use prior to the procedure.
FAQ
How many treatments are needed?
Generally, one treatment session is sufficient. The number of sessions required varies from person to person, and additional sessions may be performed if the results are unsatisfactory.
Do personalized PRP injections hurt?
We administer anesthesia before the procedure, but pain sensitivity varies from person to person. Please consult with us in advance if you have any concerns.
How much downtime is there?
Redness may occur immediately after the treatment. The time it takes for the redness to subside varies from person to person.
Can I apply makeup right after the treatment?
You should avoid strong stimulation to the injection site on the day of treatment, but you can wear makeup as usual starting the next day.
Can personalized PRP injections be used for areas other than nasolabial folds?
Yes, it is possible. We treat dark circles under the eyes, forehead wrinkles, sunken eyes, wrinkles around the mouth, and the backs of the hands, among other areas. We will explain whether you are a suitable candidate following a consultation.
Are there any side effects or risks?
Mild redness, swelling, or bruising may occur after the procedure (these symptoms usually subside within a few days). In very rare cases, allergic reactions or tumor formation at the treatment site have been reported, and it is not possible to completely eliminate these risks.
Please feel free to reach out first
We welcome your questions, concerns, and free counseling bookings regarding Personalized PRP injection.
Following your examination, we will explain the treatment plan, costs, and risks.
We’re happy to provide consultations only.
Our Commitment to Addressing Your Skin Concerns
Various facial concerns, such as,It's not just a matter of appearance...No.For daily joy and a sense of self-worthI think this is an important issue that concerns us all,I'm thinking about it.
As we get older ourselves,"I wonder if my nasolabial folds have gotten a little deeper...""My dark circles are a little noticeable today, so I might look tired..."I even found myself worrying about that.
Just one change in your face,Fashion and interpersonal relationshipsI started to enjoy it, andTo enjoy life even moreYou might find yourself able to do it.
We offer personalized PRP injections,It's not just about improving the appearance, but rather,A Positive Outlook on Life ItselfA trigger for being caughtWe consider this to be a treatment that will result in...
Under the supervision of a board-certified specialist in anti-aging medicine,Explanation of the Treatment and RisksWe are thorough.
It is true that this is a costly treatment.But more than that,"I want to enjoy the rest of my life more."For customers who think,Once you are satisfied with this,With the treatment options available,That is what I hope to achieve.
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising Guidelines Medical Advertising Guidelines revised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last Reviewed: August 1, 2026