Water light injection x Exosome [umbilical cord derived].

Hello, I am a doctor at Smart Skin Clinic, an aesthetic dermatology clinic.

Do you have any of these questions or concerns?

In this article,Having obtained a Ministry of Health, Labour and Welfare Type 2 Regenerative Medicine Provision Plan Number,Smart Skin Clinic, a cosmetic dermatology clinic specializing in regenerative medicine, offers a clear explanation from a professional standpoint.

*If you are comparing clinics and would like to know pricing and other details, please choose the item of interest from the table of contents below.

Supervisor Information

Group Chief Director, Smart Skin Clinic Group

IshiiIshii KotaKota

Career

Graduated from Juntendo University School of Medicine

Worked at Tokyo Women's Medical University Hospital and affiliated facilities

Worked at a major aesthetic clinic in Tokyo

Affiliations / Qualifications

Board-certified specialist, Japan Surgical Society

Board-certified specialist, Japanese Society of Anti-Aging Medicine

What is a Water Light Injection x Exosome?

This is a treatment in which an exosome preparation is injected into the face using a machine for injecting products called the Water Light Injection.

For details on the machine called the Water Light Injection, please also see the article below.

Exosomes are components naturally present in the body and have a cell-activating action that delivers anti-aging effects.

If you would like to learn more about exosomes, please also see the article below.

Effect

The following effects on the skin may be expected.

Features of Smart Skin Clinic's exosome preparation

Use of umbilical cord–derived exosomes

At Smart Skin Clinic, of the three major types of exosomes—(1) umbilical cord-derived, (2) fat-derived, and (3) dental pulp- and bone marrow-derived—we use "(1) umbilical cord-derived" exosomes.We use them in our treatments.

Compared with other exosomes, umbilical cord–derived exosomes contain more than 14 times the amount of active components, as shown in the figure below.

We would also like to highlight two of these "active ingredients," including specific data.

(1) Rich in active ingredients for the skin

The first is data on the active ingredients for the "skin."

Exosomes offer a variety of anti-aging effects, one of which is their effect on the "skin." As the figure below shows, umbilical cord–derived exosomes contain a richer concentration of active ingredients for the skin than other exosomes.

(2) Rich in the rejuvenating protein "GDF-11"

The second is data on components involved in "rejuvenation."

There is a component called GDF-11 that is involved in rejuvenation, and umbilical cord–derived exosomes contain it in abundance, as the data below shows.

Our "commitment" to price and quality

At our clinic, we are committed to price and quality. To realize this commitment, we take various measures, including a range of cost-cutting efforts (for example, not making the interior lavish, and reducing labor costs by eliminating the reception desk).

For details, please see here.

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A post shared by Smart Skin Clinic [Aesthetic Dermatology] Jimbocho Juvelook & Profhilo & Sunekos (@smartskin_clinic)

Smart Skin Clinic's "commitment" to Water Light Injections

View this post on Instagram

A post shared by Smart Skin Clinic [Aesthetic Dermatology] Jimbocho Juvelook & Profhilo & Sunekos (@smartskin_clinic)

Safety Initiatives | Compliance with the Guidance of the Japanese Society for Regenerative Medicine

Our Exosome IV drip therapy is carried out in accordance with the "Guidance on the Clinical Application of Extracellular Vesicles, etc. (1st Edition)," published by the Japanese Society for Regenerative Medicine on April 30, 2024.

This guidance serves as an important set of principles for ensuring the safety and efficacy of exosome therapy, and at our clinic we carry out rigorous quality control and safety measures based on this guidance.

Our clinic's specific measures to ensure safety

1. Conducting risk profiling
   • We identify the potential risks associated with treatment and take appropriate measures.
2. Rigorous preparation processes and quality control
   • Our manufacturing processes and quality checks are based on the latest scientific findings.
3. Carrying out appropriate verification of effectiveness
   • We continually assess the effectiveness of treatment and strive to provide the most suitable care for each patient.

Placing your safety first, we are committed to providing treatment grounded in the latest scientific findings.

Recommended number/frequency of treatments | How many times should I have it?

This is a question we're often asked during actual counseling, so we'll explain it just as we would tell you at the clinic.

"How many times should I receive Exosome Water Light Injections for the best results?"

A set of 3 to 4 sessionsis what we would suggest.

"What is the ideal interval between sessions?"

At intervals of about one monthwould be a good idea.

*The reason we don't speak in absolutes is that with cosmetic dermatology treatments, results vary from person to person, so we're neutrally conveying the methods generally recommended in cosmetic dermatology and by manufacturers. While we don't make guarantees, we generally recommend receiving treatment at the number of sessions and frequency described above.

How to space out other treatments

Many people have had other cosmetic treatments beforehand or wish to have them in the future, so we often receive questions like this during counseling.

We will explain this so that reading it resolves your questions.

"I'm also having laser treatment—how long should I space it out?"

As a general rule, allow about one month between sessions.

This basic guidance applies not only to lasers but to other treatments as well.

"Can I have other treatments on the same day?"

As a rule, we do not recommend other treatments on the same day.

Risks and Side Effects・Downtime

Risks, side effects, and downtime may mean roughly the same thing to you, so we will explain them together.

The above reactionssubside within 24 hours in most cases.Swelling from the product often subsides within about 3 hours.

Another point we always make sure to mention is"bruising."the possibility that it may occur. This is sometimes misunderstood, so let us explain it carefully.

First, please see below.

As noted here, bruising occurs at a certain frequency (about 3–10%).

Bruising happens when the needle strikes a "blood vessel (a vein)" beneath the skin, causing a small tear so that blood leaks out and clots.

In other words, to prevent this, it is best "not to hit a blood vessel," but these blood vessels (veins) are very thin, and their course (where they run) differs from person to person. For this reason, it cannot be prevented 100%.

At Smart Skin Clinic, we make every effort to lower the risk of bruising as much as possible. We would appreciate your understanding of this when you visit.

Aftercare｜advice for daily life after treatment

First we will summarize the "what not to do" items, and then explain the reasons in detail.

So, let us first summarize "what not to do" after the treatment.

Next, we will briefly explain "why you should not do these things."

The area injected with the drug will have mild"state of inflammation."This is the case.

Inflammation, put simply,"is a state in which the body is working hard to return to its original condition."That's how we can describe it. Since the body is working hard to improve the injection site, it is best to leave it alone.

What the "things not to do within 24 hours" have in common is "excessively increasing blood flow or applying heat." These can promote inflammation, which may result in a condition called "post-inflammatory hyperpigmentation" or slow the healing process.

In short,"To avoid promoting inflammation, don't irritate the area and let it heal naturally."That is what we mean.

Level of pain｜need for anesthesia

The pain of Exosome Water Light Injections is moderate to high.

Pricing

Treatment Flow

Those who are not eligible for the treatment

In principle, the treatment can be performed unless you have some serious illness or inflammation in the area to be treated.

The following is provided as reference information, since we are obliged to include it to inform "those who are not eligible for the treatment," so please take a quick look through it.

FAQ

Will I be unable to donate blood?

Blood donation is possible.
If exosomes are injected into the skin, as with Dermapen or Water Light Injection, it's fine. If they enter the bloodstream, you will no longer be able to donate blood.

Details

Treatment Time	About 30 to 45 minutes (not including counseling)
Recommended Number & Frequency of Treatments	About 3 to 4 times at one-month intervals
Downtime	About 24 hours
Treatment on the day of counseling	Available
Makeup	From the next day
Skincare	From the next day
Shower	Possible from the same day
Pain	Pain at the moment the needle is inserted and when the product is injected

Smart Skin Clinic

Smart Skin Clinic

A clinic built on the concept of "making aesthetic medicine more accessible and smart."

Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.

We aim to "make aesthetic medicine more accessible" for you.

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Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialties: Aesthetic Dermatology (aesthetic dermatology, medical hair removal, medical body contouring)

Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialties: Aesthetic Dermatology (aesthetic dermatology, medical hair removal, medical body contouring)

About the physician supervision of this site

About the physician supervision of this site

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This site is operated under the supervision of Smart Skin Clinic's supervising physicians.

This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.

This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.