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NEOFOUND Hydrophotonic Injection (NEOFOUND)
"What kind of injection is a NEOFOUND injection?"
"I'd like to try NEOFOUND, so I'm comparing clinics where I could receive it."
"Dark circles and wrinkles under my eyes and sagging cheeks make me look older than my actual age."
"I wonder if there's a good way to get rid of spots and dullness."
Now in your 30s or 40s, have you resigned yourself to the idea that "it's inevitable that skin concerns increase with age—that's just how it is"?
It is true that, as the skin's metabolism slows with age and the production of collagen and elastin declines, concerns such as spots, wrinkles, and sagging arise. However, that does not mean there is no way to improve them.
In this article, I—a doctor at the cosmetic dermatology practice Smart Skin Clinic—will explain, in clear and professional terms, "NEOFOUND," a groundbreaking treatment for improving the skin concerns that bother you and achieving your ideal, beautiful skin. Please do read on.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
NEOFOUND's main ingredients and how they work
NEOFOUND's key feature lies in the synergy between non-cross-linked hyaluronic acid and amino acids. Non-cross-linked hyaluronic acid penetrates deep into the dermal layer, enhancing water retention while promoting the production of collagen and elastin. Amino acids activate fibroblasts and support the creation of firm, elastic skin.
The main ingredients of NEOFOUND are as follows.
- non-cross-linked hyaluronic acid
- Amino acids (glycine, proline, arginine)
- Acetylcysteine (an antioxidant component)
- Resveratrol (an antioxidant component)
- Niacinamide (Vitamin B3)
In addition, three antioxidants provide powerful support for skin beautification. Acetylcysteine helps prevent spots and freckles through the production of glutathione. Resveratrol activates the longevity gene SIRT1 to help counter aging. Niacinamide offers a dual effect of brightening and helping to reduce rough skin.
In addition, acetyl hexapeptide contributes to the improvement of expression wrinkles. Formulated with 100% naturally derived ingredients, it effectively addresses skin concerns while minimizing the burden on the skin.
NEOFOUND's effects, based on scientific evidence
NEOFOUND's effects have been scientifically demonstrated through numerous clinical trials, primarily in Italy.
Comparative studies with other ECM formulations have also made NEOFOUND's advantages clear. While delivering effects that are equal to or greater than those of other formulations, it has an extremely low incidence of side effects, confirming its high level of safety.
Improvement of spots, freckles, and dullness:
・The combination of non-cross-linked hyaluronic acid and amino acids enhances the skin's water retention and promotes cell turnover, which may help improve spots, freckles, and dullness
・Acetylcysteine and niacinamide suppress melanin production for a brightening effect
Improvement of wrinkles and sagging:
・The combination of non-cross-linked hyaluronic acid and amino acids promotes the production of collagen and elastin in the dermal layer, improving skin firmness and elasticity
Improvement of skin firmness and elasticity:
・The combination of non-cross-linked hyaluronic acid and amino acids enhances water retention in the dermal layer and promotes the production of collagen and elastin, improving skin firmness and elasticity
・Resveratrol exerts an antioxidant effect, helping protect the skin from the reactive oxygen species that cause aging
Improvement of acne scars:
・The combination of non-cross-linked hyaluronic acid and amino acids enhances the skin's water retention and promotes cell turnover, helping improve the redness and unevenness of acne scars
Improvement of melasma:
・Acetylcysteine and niacinamide suppress melanin production and help improve melasma
Overall improvement of skin quality:
・Ingredients such as non-cross-linked hyaluronic acid, amino acids, acetylcysteine, resveratrol, and niacinamide take a multifaceted approach—water retention, cell turnover, collagen and elastin production, melanin suppression, and antioxidant action—so an overall improvement in skin quality can be expected
NEOFOUND is recommended for those who
NEOFOUND helps improve pigmentation such as spots, freckles, and dullness, brightening the skin and evening out its tone. It is particularly effective even for stubborn melasma. In treatment cases, clear improvement has been seen after two to three sessions.
It is also effective for the redness and unevenness of acne scars, helping restore smoothness to the skin. It works on wrinkles and sagging around the eyes and mouth as well, guiding the skin toward a firm, youthful appearance.
NEOFOUND treatment method and recommended protocol
The NEOFOUND procedure uses ultra-fine needles to deliver the ingredients deep into the dermal layer, drawing out the maximum effect.
The recommended protocol is a course of 4 sessions at 1-to-2-week intervals, followed by ongoing maintenance every 4 to 6 months. By the end of the first course, noticeable changes begin to appear, and with each additional maintenance session, the effects continue to build.
Another major advantage is that there is virtually no downtime after the procedure, allowing you to return to daily life right away.
The synergy between NEOFOUND and chemical peeling
Combining NEOFOUND with chemical peeling further enhances its effects. Through the synergy of peeling, which promotes turnover of the epidermis, and NEOFOUND, which acts on the dermal layer, brightening from deep within the skin is achieved.
A greater improvement can be expected for pigmentation such as spots, freckles, and dullness. Combining it with peeling can draw out the full skin-beautifying potential of NEOFOUND.
The best timing for NEOFOUND treatment and the importance of continuity
NEOFOUND treatment is ideal for anti-aging care from your 30s onward. Once you begin to notice spots and wrinkles, we recommend starting treatment early. Being proactive with care from a younger age can also help prevent the signs of aging skin.
In addition, to maintain and further enhance NEOFOUND's effects, ongoing treatment is essential. Regular maintenance keeps your skin condition at its best at all times. You can continue to keep your skin vibrant and beautiful even as you age.
NEOFOUND pricing
NEOFOUND Water Light Injection treatment
| 3cc | Limited-time discount price (until July 31) | Per 1 cc Price |
|---|---|---|
| Once (10% off) | 26,820 yen | ¥8,940 |
| 3 times (20% off) | ¥64,320 (¥21,440 per session)) | 7,100 yen |
| 5 sessions (20% off) | 95,200 yen (per session ¥19,040) | 6,300 yen |
| 6cc | Limited-time discount price (until July 31) | Per 1 cc Price |
|---|---|---|
| Once (10% off) | 40,320 yen | ¥6,720 |
| 3 times (20% off) | 95,520 yen (¥31,840 per session) | 5,300 yen |
| 5 sessions (20% off) | 139,200 yen (per session ¥27,840) | 4,600 yen |
Need for Anesthesia | High
Prices shown are all-inclusive, covering anesthesia and other fees.
This is because anesthesia is recommended for this treatment, so the standard practice is to perform it after applying anesthetic cream or administering local anesthesia.
NEOFOUND, manual injection by a physician
| 3cc | |
|---|---|
| Once | 34,800 yen |
| 3 times | 92,400 yen (30,800 yen per session) |
| 5 sessions | 134,000 yen (26,800 yen per session) |
| [Monitor] 5 sessions | 124,000 yen (24,800 yen per session) |
| 6cc | |
|---|---|
| Once | 52,800 yen |
| 3 times | 143,400 yen (47,800 yen per session) |
| 5 sessions | 214,000 yen (42,800 yen per session) |
| [Monitor] 5 sessions | 204,000 yen (40,800 yen per session) |
Need for anesthesia | Low
This treatment generally does not require anesthesia.
We would like to keep this pricing, so if you would like numbing cream we charge[5,500 yen (tax included) per session]for it. (*This is because anesthesia adds about 20 minutes to the treatment time.)
Features of Smart Skin Clinic's Water Light Injection
Summary
NEOFOUND is a groundbreaking treatment that draws out the skin's natural power to achieve beautiful skin from within. It works on all kinds of skin concerns—spots, wrinkles, sagging, and more—and delivers reliable results grounded in scientific evidence.
At Smart Skin Clinic, we propose a made-to-order NEOFOUND treatment plan tailored to each individual's skin condition. Through careful counseling and treatment, we help you achieve your ideal, beautiful skin. With NEOFOUND, let's help you attain a beauty that stands up to the years.
Related Pages
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising Guidelines Medical Advertising Guidelines revised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last supervision date: June 26, 2025