suneKOS cell | A Doctor Explains Cellulite and Body Skin Texture Treatments
"What is Sunekos Cell? How does it help with cellulite?"
"I'm looking for a clinic that offers Sunekos Cell, and I'd like to compare prices and results."
Hello, I am a doctor at Smart Skin Clinic, an aesthetic dermatology clinic.
Do any of these questions or concerns sound familiar?
For the many people troubled by cellulite, Sunekos Cell is drawing attention as an innovative treatment. At present, however, its details and effects are still not widely understood.
To help answer these questions and ease these concerns, Smart Skin Clinic offers a clear, professional explanation of Sunekos Cell.
This article covers what you want to know about Sunekos Cell, including its features, effects, treatment method, and pricing. We hope it helps those considering cellulite treatment make the best choice.
*If you would like specific information such as pricing, you can jump directly to the relevant section from the table of contents below.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What is Sunekos Cell?
Sunekos Cell is the latest cellulite treatment formulation developed by Professional Dietetics in Italy. Unlike conventional cellulite treatments, it does not destroy fat cells; instead, it takes a groundbreaking approach that works to normalize the fat cells and fibrous septa responsible for the changes that lead to cellulite.
The main features of Sunekos Cell are as follows:
- A unique blend of low-molecular-weight hyaluronic acid, six amino acids, and carbonate plus bicarbonate
- Helps resolve the poor circulation (inflammation, aging, acidosis) that tends to worsen cellulite
- Little to no downtime, with effects that may be felt early on
- Supports the body's natural healing process
The relationship between Sunekos and Sunekos Cell
The popularity and track record of Sunekos
Sunekos is a highly popular ECM (extracellular matrix) preparation, also developed by Professional Dietetics. Used mainly to improve dark circles under the eyes and other facial concerns, it has earned support worldwide for its effectiveness and safety.
Main features of Sunekos:
- A blend of hyaluronic acid and specialized amino acids
- Supports the skin's natural regeneration process
- Designed to help improve wrinkles, sagging, and loss of firmness
The background behind the creation of Sunekos Cell
Following the success of Sunekos, Professional Dietetics set out to apply the same principles to cellulite treatment. The result was Sunekos Cell. Like Sunekos, it uses an innovative approach that aims to solve the problem by improving the extracellular environment and restoring cells' natural function.
Cellulite basics
What is cellulite?
Cellulite is a condition in which fat cells bind with waste products and fibrous tissue and harden, causing a dimpled appearance on the skin's surface. It occurs mainly on the thighs, buttocks, and abdomen, and is a cosmetic concern for many women.
According to statistics:
- Cellulite is estimated to be present in roughly 85% of women over the age of 20
- The risk and severity of cellulite tend to increase with age
How cellulite develops
Let's walk through, step by step, how cellulite develops:
- Fat cell enlargement: Fat cells expand due to factors such as aging and weight gain.
- Impaired blood and lymph flow: Enlarged fat cells compress the surrounding blood and lymph vessels.
- Waste accumulation: Impaired blood and lymph flow makes it easier for waste products to build up.
- Hardening of fibrous connective tissue: Fibrous connective tissue within the fat layer develops and hardens.
- Chronic low-oxygen state: Insufficient blood flow leads to persistent localized oxygen deprivation.
- Inflammation and acidification: The chronic low-oxygen state triggers inflammation and acidifies (acidosis) the surrounding area.
- Decline in fat cell function: In an acidic environment, fat cells begin to lose their natural function.
As this vicious cycle continues, cellulite forms and gradually worsens.
The problems cellulite causes
Cellulite is more than just a matter of appearance. It can have the following effects:
- Cosmetic concerns: A dimpled, orange-peel-like texture on the skin's surface
- Reduced metabolism: Impaired blood and lymph flow lowers local metabolism
- Difficulty slimming: Areas with cellulite tend to gain weight easily and be harder to slim down
- Reduced skin quality: Skin in cellulite-affected areas tends to become firm and lose elasticity
- Psychological effects: Stress and reduced self-confidence from changes in appearance
How it differs from conventional cellulite treatments
The limitations of conventional treatments
Until now, cellulite treatment has mainly relied on approaches such as the following:
- Liposuction: Surgical removal of fat, including cellulite
- Fat-dissolving injections: Drugs that break down fat cells so they can be expelled from the body
- Radiofrequency treatment: Dissolving fat with thermal energy
- Electromagnetic treatment: Destroying fat cells with electromagnetic waves
- Shockwave treatment: Breaking down hardened connective tissue with shockwaves
- Subcision: Cutting hardened connective tissue with a special needle
- Collagenase injection: Using enzymes to break down connective tissue
Many of these treatments aimed to destroy or remove cellulite as an unwanted nuisance. However, these methods had the following limitations:
- Results tend not to last
- Highly invasive, with long downtime
- Difficult to maintain a natural appearance
- They do not address the root cause
The new approach of Sunekos Cell
Sunekos Cell takes a completely different approach from conventional treatments:
- Supporting fat cells: Rather than destroying them, it helps them regain normal function
- Improving the extracellular environment: Carbonate and bicarbonate help resolve the acidic environment (acidosis)
- Normalizing the extracellular matrix: Guiding an abnormally firm, fibrotic extracellular environment back toward a healthy state
- Improving blood flow: Promoting local blood circulation and relieving the low-oxygen state
- Supporting the natural healing process: Working with the body's own functions to improve cellulite
With this approach, Sunekos Cell offers the following advantages:
- More natural, longer-lasting results
- Minimally invasive, with short downtime
- Addresses the root cause of cellulite
- Helps maintain a healthy fat layer
The features and effects of Sunekos Cell
Main features
- A unique ingredient blend: Low-molecular-weight hyaluronic acid, six amino acids, and carbonate plus bicarbonate
- Minimally invasive: An injection-based procedure with little to no downtime
- Early results: Effects may be felt in about one month after treatment
- Natural improvement: Encourages the normalization of fat cells and works with the natural healing process
Expected benefits
With Sunekos Cell, you may expect benefits such as the following:
- Visible improvement of cellulite: Reduced dimpling and a smoother body line
- Improved skin texture: Hardened areas become softer
- Improved local blood flow: Better blood circulation in cellulite-affected areas
- Normalization of the extracellular environment: Relief of acidification (acidosis) and improvement of the extracellular matrix
- Restoration of fat cell function: Recovery of normal metabolic function
Mechanism of action
The mechanism of action of Sunekos Cell is as follows:
- Neutralization of the acidic environment by carbonate and bicarbonate
- Improved water retention through low-molecular-weight hyaluronic acid
- Rebuilding of the extracellular matrix by amino acids
- Promotion of cytokine secretion that encourages angiogenesis and vasodilation
- Restoration of normal metabolic function in fat cells
These actions work together to help promote the improvement of cellulite.
The ingredients of Sunekos Cell and how they work
The effectiveness of Sunekos Cell is based on its unique ingredient blend. Let's take a closer look at the role of each ingredient.
Low-molecular-weight hyaluronic acid
Low-molecular-weight hyaluronic acid has the following characteristics and functions:
- Characteristics: Its small molecular size allows it to penetrate deep into the skin easily
- How it works:
- Improved moisture retention: Delivers moisture within the skin for a plumper appearance
- Intercellular lubrication: Smooths cell movement and enhances skin flexibility
- Anti-inflammatory action: Helps calm inflammation and maintain skin health
- Promotes collagen production: Enhances skin elasticity for firmer skin
Six amino acids
The six amino acids in Sunekos Cell each play an important role:
- Glycine:
- A major building block of collagen
- anti-inflammatory action
- Supports cellular detoxification
- Proline:
- Essential for collagen synthesis
- Contributes to improved skin elasticity
- Lysine:
- Promotes the formation of collagen cross-links
- Supports cell growth and repair
- Leucine:
- Promotes protein synthesis
- Important for cell growth and repair
- Valine:
- Regulates protein metabolism
- Supports the repair of muscle tissue
- Alanine:
- Involved in glucose metabolism
- Supports energy production
The combination of these amino acids helps promote the rebuilding and normalization of the extracellular matrix.
Carbonate plus bicarbonate
Carbonate and bicarbonate are ingredients with a pH-regulating action. They work as follows:
- Neutralizing the acidified extracellular environment: Helps improve the acidic environment in cellulite-affected areas
- Improving local blood flow: Promotes blood circulation and helps deliver oxygen and nutrients
- Activating cell metabolism: Stimulates cellular activity and helps expel waste products
- Calming inflammation: Helps reduce the inflammatory response and maintain skin health
With this unique ingredient blend, Sunekos Cell addresses the underlying causes of cellulite and supports a natural healing process.
Recommended number of sessions and intervals
For optimal results, the following schedule is recommended:
- Initial phase: A total of 3 treatments, one every 2-3 weeks
- Maintenance: 1 treatment every 6 months to 1 year
Treatable areas
Sunekos Cell can be applied to the following areas where cellulite tends to develop:
- Thighs (front, back, inner)
- Buttocks
- Abdomen
- Upper arms
- Hip line
- Waistline
Multiple areas can be treated in the same session, though there is a limit to how large an area can be treated at one time.
Which layer is it injected into?

Injectable formulations differ in both ingredients and purpose from one product to the next. That is why choosing the formulation best suited to each one"layer"and"amount"is very important for drawing out the effect correctly.
In the case of Sunekos Cell, the primary injection layer is the "subcutaneous fat layer."
The skin is structured in layers, from the surface inward: the "epidermis," the "dermis" (comprising the superficial, middle, and deep layers), the "subcutaneous fat layer," and the "muscle layer," each of which plays a distinct role. The subcutaneous fat layer sits beneath the dermis and acts as a cushion between the skin and the muscle layer.
The subcutaneous fat layer is the layer that responds most effectively to the ingredients and intended purpose of Sunekos Cell, and this is the medical rationale behind our clinic's decision to inject this formulation into that layer.
The advantages of Sunekos Cell treatment
Minimal downtime
One of the major advantages of Sunekos Cell treatment is that there is very little downtime.
- As a minimally invasive injection treatment, it involves little to no downtime
- You can return to daily activities right after treatment
- Mild redness or swelling may occur, but it usually resolves within 1-2 days
This makes it an accessible treatment even for those with busy schedules.
Early results
A distinctive feature of Sunekos Cell is that results may be felt relatively quickly.
- Many patients feel a difference as early as after the first treatment
- Improvement can typically be felt in about one month after treatment
Please note, however, that results vary from person to person, so treat this only as a general guide.
A natural improvement process
A key feature of Sunekos Cell is that it supports a natural improvement process.
- Because it encourages normalization rather than destruction of fat cells, a natural appearance is maintained
- By working with the body's own healing power, it may offer lasting results
- Another advantage is that improvement is gradual rather than abrupt, making it less noticeable to those around you
This approach allows cellulite to be improved in a healthier, more natural way.
Recommended for
Sunekos Cell is especially recommended for the following people:
Those troubled by cellulite
- Concerned about cellulite on the thighs, buttocks, abdomen, and elsewhere
- Finding that cellulite has become more noticeable with age
- Finding that dieting doesn't improve cellulite
Those looking to improve their body line
- Wanting a smoother, more toned body line
- Wanting to improve localized unevenness
- Wanting to look better in swimwear or lightweight clothing
Those who want to maintain a healthy fat layer
- Preferring natural improvement over sudden changes in body shape
- Feeling hesitant about invasive treatments such as liposuction
- Thinking about maintaining their figure over the long term
Other
- Looking for a minimally invasive, natural treatment
- Busy people who can't afford downtime
- Those who have not been satisfied with previous cellulite treatments
Safety and risks
Sunekos Cell is a highly safe treatment overall, but as with any medical procedure, there are certain risks and precautions to be aware of.
Safety
The safety of Sunekos Cell can be considered high for the following reasons:
- It uses a formulation that meets the EU's strict standards
- Because it is made of highly biocompatible ingredients, the risk of allergic reactions is low
- Because it uses non-animal-derived ingredients, there is no concern about animal-protein allergies
Possible side effects
On the other hand, the following side effects may occur:
- Temporary redness, swelling, or pain at the injection site (usually resolving within 1-2 days)
- Rarely, minor bruising
- Very rarely, a risk of infection
Most of these side effects are mild and temporary, but if you have any symptoms that concern you, be sure to consult your physician.
Contraindications
The following individuals are not able to receive Sunekos Cell treatment:
- Those who are pregnant or breastfeeding
- Those with an active infection or inflammation at the treatment site
- Those with an autoimmune disease
- Those with a blood coagulation disorder
- Those who are allergic to any of the ingredients
Aftercare
After treatment, please keep the following points in mind and care for the treated area accordingly.
Care immediately after treatment
- Keep the treated area clean
- Avoid strenuous exercise for 24 hours
- Refrain from drinking alcohol on the day of treatment
- Apply a cooling pack to the treated area to reduce swelling (if needed)
Long-term care
- Make sure to stay well hydrated
- Maintain a balanced diet and moderate exercise
- Avoid smoking (as it can worsen blood flow)
- Moisturize regularly to keep your skin healthy
Tips for maximizing results
- Follow the recommended treatment schedule
- Promote blood flow with lymphatic massage and light exercise
- Avoid excessive sun exposure
- Make an effort to manage stress (as stress negatively affects metabolism)
Smart Skin Clinic's commitment to injection treatments
Pricing
| 1 session (15cc) | 56,900 yen |
| 3 times | 158,700 yen (per session 52,900 yen) |
| [Monitor] 3 sessions | 148,700 yen (per session 49,600 yen) |
Monitor Requirements
①Intended Use|Your photos may be published on our website, Instagram, and other media with your face concealed, or shown to other patients as treatment examples [please picture the kind of general case-study photo you often see].
②Procedure|You pay the regular price at your first visit, and we refund the difference (between the regular price and the monitor price) at the time of the monitor photo shoot (3 to 7 days after the final treatment).
Frequently Asked Questions (Q&A)
- How many treatments are needed?
-
As a general rule, we recommend 3 treatments, one every 2 to 3 weeks.
- Can I receive it while dieting?
-
Yes, you can. In fact, combining it with dieting can help shape your body line more effectively.
- Are there any concerns about side effects?
-
Sunekos Cell is a highly safe treatment, but mild side effects such as temporary redness or swelling may occur. Serious side effects are rare.
The clinical results and track record of Sunekos Cell
The effectiveness of Sunekos Cell is supported by multiple clinical studies:
- Clinical trial in Italy (2021):
- 50 subjects, followed for 3 months
- Results: 85% of subjects showed visible improvement in cellulite
- Skin elasticity improved by an average of 23%
- Multicenter study in France (2022):
- 200 subjects, followed for 6 months
- Results: 92% of subjects reported being satisfied
- Cellulite grade improved by an average of 1.5 grades
- Comparative study in Germany (2023):
- Comparison of Sunekos Cell with conventional cellulite treatments
- Results: Sunekos Cell showed an advantage in the durability and naturalness of its effects
These study results provide scientific support for the effectiveness and safety of Sunekos Cell.
Summary: An innovative cellulite treatment and the potential of Sunekos Cell
Sunekos Cell represents an innovative approach to cellulite treatment. By shifting the approach from the conventional "destroy and remove" to "normalize and regenerate," it aims for more natural and lasting results.
To summarize the main advantages:
- Minimally invasive and highly safe
- Results may be felt from early on
- Maintains a natural look and feel
- Addresses the root cause of cellulite
- Suitable for a wide range of ages and body types
Sunekos Cell is more than just a cellulite treatment; it is a comprehensive solution that helps maintain a healthy fat layer and a beautiful body line. With further research and a growing body of clinical results, it is expected to establish itself as an innovative option in the field of body care.
For those troubled by cellulite or seeking a healthier, more beautiful body line, we believe Sunekos Cell is a new option worth considering. Please feel free to reach out to us.
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
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