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Jubelook Injection Yahoo!
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What Is Juvelook?
Juvelook is an injectable formulation that combines non-crosslinked hyaluronic acid with “poly-DL-lactic acid (PDLLA)” , and is classified as a “skin booster.”
After injection, it is slowly absorbed by the body over the course of 1 to 2 years. During this time, it stimulates fibroblasts to naturally increase collagen and elastin production, resulting in long-lasting effects.
Because it is made from lactic acid, which is also naturally present in the human body, it is a formulation that is unlikely to cause allergies.
In English, Juvelook is spelled "JUVELOOK."
It is a coined word combining JUVE (youth, vitality, energy) and LOOK (appearance, expression).
It is also approved by the body equivalent to Japan's Ministry of Health, Labour and Welfare, namely theU.S. Food and Drug Administration (FDA)and theApproved by the Korea Food and Drug Administration (KFDA)It is a formulation.
Juvelook Case Photos (Before/After)
Before Viewing the Case Photos
- Treatment Details:Jubelook injections. This is a self-pay service (not covered by public health insurance).
- Cost (including tax):HydraFacial Injection: 3 cc per session, starting at 36,800 yen / Administered by a physician; Full Face (3 cc), starting at 51,800 yen per session (All prices include anesthesia fees)
- Treatment Duration and Number of Sessions:We recommend three treatments at one-month intervals. After that, we recommend maintenance treatments about once every six months to one year.
- Main risks and side effects:Redness, swelling, pain, edema, bruising, and temporary swelling at the injection site. If subcutaneous bruising occurs, it will gradually fade over 10 to 14 days.
Below are photos of one of our clinic's monitor patients, without makeup, after two sessions of Juvelook injections.
(Effects vary from person to person and are not guaranteed.)
The case photos below show an overall improvement in skin quality and a shift toward a brighter appearance.
In the case photos below, you can see "sagging" and "softened nasolabial folds."
In the case photos below, you can see "improvement of skin redness," "improvement of pore opening," and "improved firmness and radiance of the skin."
In the case photos below, you can see an even greater "improvement of skin redness," "improvement of pore opening," and "improved firmness and radiance of the skin."
The following case photos clearly show "improvement in post-acne marks."
Acne scars (craters)
A skin booster originating in South Korea and certified by the KFDA
Juvelook won an award in Korea's consumer skin booster category for two consecutive years (2022, 2023).
A total of 41 brands, including Starbucks, Terra, and Jubelk, were selected for the 2023 Korea Consumer Award (Korea Consumer Award, 2023).
The Four Features of Juvelook
1. Long-lasting effect
Poly-DL-lactic acid (PDLLA) continuously stimulates the fibroblasts within the skin, which in turn promotes collagen production. After injection, it is slowly broken down into water and carbon dioxide within the skin over one to two years. For this reason, unlike conventional hyaluronic acid formulations, Juvelook is a formulation that nurtures the skin over an extended period.
The official Juvelook YouTube video below explains how Juvelook works. (*The video is in English.)
(2) Relatively few side effects
Juvelook uses a drug called poly-DL-lactic acid (PDLLA). Poly-lactic acid formulations in the same category as Juvelook include Sculptra and Maccume.
Sculptra had angular, pointed particles that strongly irritated surrounding cells and carried a risk of causing subcutaneous lumps.
Maccume is a delivery agent for Potenza. It greatly reduced the risk of the subcutaneous lumps that tended to occur with Sculptra. However, because it is not approved by the Korea Food and Drug Administration (KFDA), it cannot be injected directly into the skin.
Unlike Sculptra and Metacrill, Juvelook is made so that its particles are round in shape. Because of this, the risk of forming subcutaneous lumps is low. It has also been approved by the Korea Food and Drug Administration (KFDA) and the U.S. FDA.
3. Customized treatment possible with localized injection
Juvelook can be injected not only across the whole area but also into localized spots. This makes it possible to address not only the entire face but also localized concerns. For example, it can address the following localized areas.
- Acne scars and scar indentations
- Fine lines and sagging under the eyes
- Pores on the nose
4. Extensive medical data
Juvelook is widely used in Korea, and there are many research papers on its efficacy.
As one example, the following paper discusses the efficacy of PDLA (approximately equivalent to Juvelook) for acne scars.
Intradermal injection of PDLA may be used as an effective treatment with fewer side effects in patients with acne scars of Fitzpatrick skin types III-IV.
Hyeong JH et al. (2022). Intradermal Injection of Poly-D, L-Lactic Acid Using
Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial, DERMATOLOGIC SURGERY December 2022, Volume 48-12
Recommended for
- Those who have not achieved satisfactory results with laser treatment
- Those concerned about uneven acne scars
- Those concerned about fine lines under the eyes
- Those who want to improve skin firmness and elasticity
- Those who want to refine the appearance of open pores
- Those who want to improve their skin quality
- Those concerned about wrinkles on the neck
Treatment Method
There are three main ways to inject Juvelook.
- Manual injection by a physician
- Water Light Injection (mechanical)
- Potenza
1. Manual injection by a physician
The physician checks the condition of the skin and injects at the appropriate depth and dosage for each area. The injection is performed using a syringe.
2. Water Light Injection (mechanical injection)
The term "Water Light Injection" is sometimes used as the name of a drug or formulation, but more often it is used as the name of a "machine."
Once the drug is loaded into the Water Light Injection machine and the injection depth and dosage per injection are set on the machine, it can keep injecting at a fixed depth and dosage. With Water Light Injection, a nurse performs the procedure.
3. Potenza
Potenza is a type of treatment device known as microneedle RF. It is sometimes called an advanced version of the Dermapen.
After ultra-fine needles are inserted, RF waves (radio waves) are emitted from the tips of the needles. This creates channels in the skin, into which the formulation (Juvelook) is delivered through what is known as a drug delivery system.
TreatmentArea
There are two main treatment approaches.
(1) Full-face injection
With full-face injection, the product is injected broadly across the entire face, the whole forehead, the whole cheeks, and so on. Effects such as pore treatment and improved skin quality can be expected.
(2) Localized injection
Injections are placed precisely into the frown lines, fine lines around the eyes, acne scars, and similar areas. This is the recommended approach when there are specific areas of concern.
Juvelook by Smart Skin Clinic
Uses the official Juvelook formulation approved by the FDA and KFDA
A physician injects carefully, by hand
A board-certified anti-aging specialist with over 4,000 Juvelook procedures to their creditperforms the treatment
At Smart Skin Clinic,A board-certified specialist in anti-aging medicine with extensive experience—over 4,000 procedures using Jubelook alone—and a high level of technical expertisewill always perform your treatment (*this applies to physician manual injections, not Water Light Injections).
Drawing on our extensive experience, we perform treatments that not only ensure excellent results but also take into consideration any discomfort during the procedure and swelling during the recovery period.
*Number of treatments performed based on our clinic's records
Why patients choose Smart Skin Clinic
Please compare the differences with the general trends at other clinics
-
💰 Price
General trendHigher pricingEven a Water Light Injection often costs over 50,000 yenOur clinicAffordable pricingHydraFacial (3 cc), 1 session: Starting at 36,800 yen (tax included) -
➕ Additional charges
General trendAdditional charges
tend to ariseAnesthesia fees and the like may be charged separatelyOur clinicAll-inclusive,
All-inclusive price shownTotal price including anesthesia fees -
👩⚕️ Consultation
General trendCounselor-ledThe doctor's examination can be briefOur clinicThe same physician cares for you throughoutPlease consult with us until you are fully satisfied -
🔬 Quality control
General trendQuality control is unclearThe process of preparing the products may not be visibleOur clinicThorough, transparent quality controlThe proper mixing process and more are fully disclosed
*This comparison is a general guide to "typical trends" versus our clinic's policy. It may differ depending on the clinic and the time.
Reasons for Keeping Prices Low and Quality Control
We understand some patients may feel uneasy, thinking, "If it's this cheap, it's actually scary..." "Could they be diluting it with water...?" "Are they using counterfeit products...?"
To ease these concerns, we will explain our clinic's approach and the characteristics of the drug Juvelook.
Juvelook is a "powder" product
Unlike drugs such as Profhilo and Sunekos, Juvelook comes in a box as a "powder" rather than a liquid. (See the image below.)
Because it is a powder, the following points are essential.
- It must be mixed with saline solution to dissolve it (there is a proper reconstitution method specified by the Juvelook manufacturer).
- After dissolving, it must be "stirred" (mixed thoroughly). If it is not mixed thoroughly, the effect may be uneven, or the ingredients may become unevenly distributed, creating a risk of lumps.
"Stirring" is the key point
At our clinic, we use a genuine Juvelook (JUVELOOK) mixer to stir the formulation thoroughly, as shown below.
The reason for our prices is "waste reduction and greater efficiency."
At Smart Skin Clinic, wegenuine Juvelook, at the proper concentration and by the proper method of administration.We provide it as follows.
We apply thorough quality control to every process involved in the formulation.
The reason our clinic can keep its fees low isbecause we dilute the contents.Nor is it"because we use counterfeit products."Neither is the case.
It is because, guided by our management and operating concept of "making cosmetic medicine more accessible and smarter," we thoroughly eliminate waste and maximize operational efficiency.
Who cannot receive this treatment
Those who are pregnant or breastfeeding
Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy
Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders
Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin
- Those who have excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Juvelook injection site
Risks and Side Effects
At the needle puncture site:
Redness, swelling, pain, edema
Bruising
Temporary raised bumps
Downtime
Redness and raised bumps may appear at the injection site, but they often return to normal within about 24 hours.
Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.
Treatment Flow
You can easily book from your smartphone.
A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.
During counseling, please feel free to discuss anything that’s on your mind.
After marking is done, we perform the injection while checking in with you as we go.
We will provide detailed instructions on how to care for the treated area and what to keep in mind in your daily life.
In addition, with a focus on prevention and maintenance, we recommend appropriate home care products—such as oral medications and skincare products—that can help alleviate your concerns.
Price (all prices include tax; private treatment)
Our cc breakdown of JuvelookOfficial dissolution method of Juvelook.
This information is provided because we often receive inquiries about it.
Our "cc notation" for Juvelook is the cc notation for Juvelook created using the official dissolution method of the Juvelook formulation.
What this means is that the drug Juvelook is not used as-is, but is usually dissolved in saline in the proportions prescribed by Juvelook, then mixed thoroughly, and then the dissolved Juvelook is used.
Water Light Injection (mechanical injection)
| 3cc | |
|---|---|
| Once | 36,800 yen |
| 3 sets | 95,940 yen |
| 4cc | |
|---|---|
| Once | 44,980 yen |
| 3 sets | 119,400 yen |
| 6cc | |
|---|---|
| Once | 54,980 yen |
| 3 sets | 146,640 yen |
Anesthesia｜Includes topical anesthetic cream
This procedure is performed after applying a topical anesthetic cream. The price listed includes the cost of the topical anesthetic cream.
[Reference] How to Choose the Dosage (cc)
- For easier comparison with other clinics' listings, we also offer a "3cc" option.
- That said, for the whole face (full face), 3cc does not provide sufficient "density," so if you are seeking the maximum effect, we suggest using the following as a guide when choosing.
- [Pattern 1] Lighter treatment is fine for the forehead and the area below the nose ⇒ 3cc
- [Pattern 2] The area below the nose can be a little lighter, but I want thorough treatment above the nose ⇒ 4cc
- [Pattern 3] I want thorough treatment across the whole face, including below the nose ⇒ 6cc
- If you're unsure, the doctor will ask about your preferences on the day of your appointment, and you can decide on the dosage together after discussing it.
Manual injection by a physician
| Full face (3cc) | |
|---|---|
| Once | 51,800 yen |
| 3 sets | 140,940 yen |
| 4cc | |
|---|---|
| Once | 64,800 yen |
| 3 sets | 179,820 yen |
| 6cc | |
|---|---|
| Once | 93,800 yen |
| 3 sets | 266,940 yen |
Anesthesia｜Includes topical anesthetic cream
This procedure is performed after applying a topical anesthetic cream. The price listed includes the cost of the topical anesthetic cream.
Details
| Treatment Time | About 30 to 40 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | ・It is recommended to undergo a series of three treatments at one-month intervals. ・After that, maintenance treatments are recommended approximately once every six months to one year. |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | Possible right after the treatment |
| Skincare | Possible right after the treatment |
| Shower | Possible from the same day |
| Pain | A slight pricking sensation when the needle is inserted. |
FAQ
- When will I see results?
Dr. IshiiMany people feel the effect after two to three weeks.
You can see an effect even with a single session, but it is easier to notice a significant change after receiving a set of three sessions.
We also recommend the following as an effective approach.
- A set of three sessions at one-month intervals, followed by maintenance every six months to one year.
*Because Juvelook stimulates ongoing collagen production, its effects often last for an extended period.- How is it different from hyaluronic acid treatment?
- Dr. Ishii
Hyaluronic acid treatment injects cross-linked hyaluronic acid, a firmer form of hyaluronic acid, which physically adds volume to improve wrinkles and similar concerns. Juvelook, on the other hand, achieves a natural increase in volume by boosting the collagen your own body produces.
Legal Notices
Juvelook treatment includes procedures using drugs or medical devices that are not approved in Japan. The drugs and devices used in treatment have been imported through personal importation at the discretion of our physicians.
Because Juvelook is an unapproved product in Japan, it is not covered by the Adverse Drug Reaction Relief System.
For other pharmaceuticals to be aware of regarding personal importation, please refer here.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.
We aim to "make aesthetic medicine more accessible" for you.
Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.