Jubelq injection 【Smart Skin Clinic Tokyo】Yahoo!

Supervisor Information
Kota Ishii, Chief Medical Director, Smart Skin Clinic Group

Group Chief Director, Smart Skin Clinic Group

IshiiIshii KotaKota

Career

Graduated from Juntendo University School of Medicine

Worked at Tokyo Women's Medical University Hospital and affiliated facilities

Worked at a major aesthetic clinic in Tokyo

Affiliations / Qualifications

Board-certified specialist, Japan Surgical Society

Board-certified specialist, Japanese Society of Anti-Aging Medicine

What Is Juvelook?

Jubeluk Product Images

Juvelook is a skin booster that combines non-cross-linked hyaluronic acid withPoly-DL-lactic acid (PDLLA)This is an injectable formulation known as a skin booster, made by combining

After injection, it is slowly absorbed by the body over one to two years, during which it stimulates fibroblasts to naturally increase collagen and elastin, so a lasting effect can be expected.

Because it is made from lactic acid, which is also naturally present in the human body, it is a formulation that is unlikely to cause allergies.


In English, Juvelook is spelled "JUVELOOK."
It is a coined word combining JUVE (youth, vitality, energy) and LOOK (appearance, expression).

It is also approved by the body equivalent to Japan's Ministry of Health, Labour and Welfare, namely theU.S. Food and Drug Administration (FDA)and theApproved by the Korea Food and Drug Administration (KFDA)It is a formulation.

Juvelook Case Photos (Before/After)

Below are photos of one of our clinic's monitor patients, without makeup, after two sessions of Juvelook injections.
(Effects vary from person to person and are not guaranteed.)

The case photos below show an overall improvement in skin quality and a shift toward a brighter appearance.

Jubeluk skin texture improvement case (1)

In the case photos below, you can see "sagging" and "softened nasolabial folds."

Jubeluk skin quality improvement case (2)

In the case photos below, you can see "improvement of skin redness," "improvement of pore opening," and "improved firmness and radiance of the skin."

Jubeluk skin quality improvement case (3)

In the case photos below, you can see an even greater "improvement of skin redness," "improvement of pore opening," and "improved firmness and radiance of the skin."

Acne scars (craters)

Acne scar (crater) Jubeluk case 1
Acne scar (crater) Jubeluk case 2

A Korea-born skin booster certified by Korea's KFDAskin booster

Korea Consumer Awards

Juvelook won an award in Korea's consumer skin booster category for two consecutive years (2022, 2023).

At the Korea Consumer Award, 2023,a total of 41 brands were selected, including Starbucks, Terra, and Juvelook.

The Four Features of Juvelook

1. Long-lasting effect

Poly-DL-lactic acid (PDLLA) continuously stimulates the fibroblasts within the skin, which in turn promotes collagen production. After injection, it is slowly broken down into water and carbon dioxide within the skin over one to two years. For this reason, unlike conventional hyaluronic acid formulations, Juvelook is a formulation that nurtures the skin over an extended period.

The official Juvelook YouTube video below explains how Juvelook works. (*The video is in English.)

(2) Relatively few side effects

Juvelook uses a drug called poly-DL-lactic acid (PDLLA). Poly-lactic acid formulations in the same category as Juvelook include Sculptra and Maccume.

Sculptra had angular, pointed particles that strongly irritated surrounding cells and carried a risk of causing subcutaneous lumps.

Maccume is a delivery agent for Potenza. It greatly reduced the risk of the subcutaneous lumps that tended to occur with Sculptra. However, because it is not approved by the Korea Food and Drug Administration (KFDA), it cannot be injected directly into the skin.

Unlike Sculptra and Metacrill, Juvelook is made so that its particles are round in shape. Because of this, the risk of forming subcutaneous lumps is low. It has also been approved by the Korea Food and Drug Administration (KFDA) and the U.S. FDA.

3. Customized treatment possible with localized injection

Juvelook can be injected not only across the whole area but also into localized spots. This makes it possible to address not only the entire face but also localized concerns. For example, it can address the following localized areas.

  • Acne scars and scar indentations
  • Fine lines and sagging under the eyes
  • Pores on the nose

4. Extensive medical data

Numerous medical papers

Juvelook is widely used in Korea, and there are many research papers on its efficacy.

Seyeon Oh, et al. Poly-D,L-Lactic Acid Stimulates Angiogenesis and Collagen Synthesis in Aged Animal Skin. Int. J. Mol. Sci. 2023, 24(9), 7986.

Suk Bae Seo M.D, et al. Skin rejuvenation effect of the combined PDLLA and non cross-linked hyaluronic acid: A preliminary study. J Cosmet Dermatol. 2023;00:1-9.

Seyeon Oh, et al. Poly-D,L-Lactic Acid Filler Increases Extracellular Matrix by Modulating Macrophages and Adipose-Derived Stem Cells in Aged Animal Skin. Antioxidants 2023, 12(6), 1204.

As one example, the following paper discusses the efficacy of PDLA (approximately equivalent to Juvelook) for acne scars.

Intradermal injection of PDLA may be used as an effective treatment with fewer side effects in patients with acne scars of Fitzpatrick skin types III-IV.

Hyeong JH et al (2022). Intradermal Injection of Poly-D, L-Lactic Acid Using
Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial, DERMATOLOGIC SURGERY December 2022, Volume 48-12

Recommended for

  • Those who have not achieved satisfactory results with laser treatment
  • Those concerned about uneven acne scars
  • Those concerned about fine lines under the eyes
  • Those who want to improve skin firmness and elasticity
  • Those who want to refine the appearance of open pores
  • Those who want to improve their skin quality
  • Those concerned about wrinkles on the neck

Treatment area and method

There are two main methods of injection.

(1) Full-face injection

With full-face injection, the product is injected broadly across the entire face, the whole forehead, the whole cheeks, and so on. Effects such as pore treatment and improved skin quality can be expected.

(2) Localized injection

Injections are placed precisely into the frown lines, fine lines around the eyes, acne scars, and similar areas. This is the recommended approach when there are specific areas of concern.

Juvelook by Smart Skin Clinic

Uses the official Juvelook formulation approved by the FDA and KFDA

Jubeluk by Smart Skin Clinic

A physician injects carefully, by hand

Who cannot receive this treatment

Those who are pregnant or breastfeeding

Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy

Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders

Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin

- Those who have excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Juvelook injection site

Risks and Side Effects

At the needle puncture site:

Redness, swelling, pain, edema

Bruising

Temporary raised bumps

Downtime

Redness and raised bumps may appear at the injection site, but they often return to normal within about 24 hours.

Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.

Treatment Flow

STEP
Booking

You can easily book from your smartphone.

STEP
Reception

A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.

STEP
Counseling & Examination

During counseling, please feel free to share any concerns. Rest assured, there is no pushy sales.

STEP
Juvelook injection

After marking is done, we perform the injection while checking in with you as we go.

STEP
Aftercare

We explain in detail how to care for the treated area and what to keep in mind in daily life. From a prevention and maintenance standpoint, we also suggest suitable home care, such as oral medications and skincare products that can support improvement of your concerns.

STEP
Going Home

Price (all prices include tax; private treatment)

Our cc breakdown of JuvelookOfficial dissolution method of Juvelook.

This information is provided because we often receive inquiries about it.
Our "cc notation" for Juvelook is the cc notation for Juvelook created using the official dissolution method of the Juvelook formulation.
What this means is that the drug Juvelook is not used as-is, but is usually dissolved in saline in the proportions prescribed by Juvelook, then mixed thoroughly, and then the dissolved Juvelook is used.

Water Light Injection (mechanical injection)

3cc
Once36,800 yen
3 sets95,940 yen
(per session31,980 yen)
4cc
Once44,980 yen
3 sets119,400 yen
(per session39,800 yen)
*Converted to a 3cc basis:
per session29,850 yenequivalentPrice
6cc
Once54,980 yen
3 sets146,640 yen
(per session48,880 yen)
*Converted to a 3cc basis:
per session24,440 yenequivalentPrice

Need for anesthesia | High

Prices shown are all-inclusive, covering costs such as anesthesia.
This is because anesthesia is recommended for this treatment, so it is standard to perform it with numbing cream and local anesthesia.

There are no upsells beyond the prices shown on the day of your visit.

[Reference] How to Choose the Dosage (cc)

JUVELUX dosage guidelines (1)
JUVELEC dosage guidelines (2)
JUVELUX dosage guidelines (3)
How to choose your dosage (cc)
  • For easier comparison with other clinics' listings, we also offer a "3cc" option.
  • That said, for the whole face (full face), 3cc does not provide sufficient "density," so if you are seeking the maximum effect, we suggest using the following as a guide when choosing.
  • [Pattern 1] Lighter treatment is fine for the forehead and the area below the nose ⇒ 3cc
  • [Pattern 2] The area below the nose can be a little lighter, but I want thorough treatment above the nose ⇒ 4cc
  • [Pattern 3] I want thorough treatment across the whole face, including below the nose ⇒ 6cc
  • If you are unsure, the physician will confirm your wishes on the day and suggest the optimal volume (please rest assured that we never upsell unnecessarily).

Manual injection by a physician

Full face (3cc)
Once51,800 yen
3 sets140,940 yen
(per session46,980 yen)
Monitor price (3 sets)129,800 yen
*Manual injection by a physician
4cc
Once64,800 yen
3 sets179,820 yen
(per session59,940 yen)
Monitor price
(Set of 3)
169,820 yen
6cc
Once93,800 yen
3 sets266,940 yen
(per session88,980 yen)
Monitor price
(Set of 3)
256,940 yen

Need for anesthesia | High

Prices shown are all-inclusive, covering costs such as anesthesia.
This is because anesthesia is recommended for this treatment, so it is standard to perform it with numbing cream and local anesthesia.

There are no upsells beyond the prices shown on the day of your visit.

Details

Treatment TimeAbout 30 to 40 minutes (not including counseling)
Recommended Number & Frequency of Treatments- It is recommended to perform a set of three sessions at one-month intervals.
- After that, maintenance is recommended about once every six months to one year.
DowntimeAbout 24 hours
Treatment on the day of counselingAvailable
MakeupPossible right after the treatment
SkincarePossible right after the treatment
ShowerPossible from the same day
PainA slight pricking sensation when the needle is inserted.
*Results vary from person to person.

FAQ

When will I see results?
Dr. Ishii

Many people feel the effect after two to three weeks.

You can see an effect even with a single session, but it is easier to notice a significant change after receiving a set of three sessions.

We also recommend the following as an effective approach.
- A set of three sessions at one-month intervals, followed by maintenance every six months to one year.

*Because Juvelook stimulates ongoing collagen production, its effects often last for an extended period.

How is it different from hyaluronic acid treatment?
Dr. Ishii

Hyaluronic acid treatment injects cross-linked hyaluronic acid, a firmer form of hyaluronic acid, which physically adds volume to improve wrinkles and similar concerns. Juvelook, on the other hand, achieves a natural increase in volume by boosting the collagen your own body produces.

Legal Notices

Juvelook treatment includes procedures using drugs or medical devices that are not approved in Japan. The drugs and devices used in treatment have been imported through personal importation at the discretion of our physicians.

Because Juvelook is an unapproved product in Japan, it is not covered by the Adverse Drug Reaction Relief System.

For other pharmaceuticals to be aware of regarding personal importation, please refer here.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."

Smart Skin Clinic

Smart Skin Clinic

A clinic built on the concept of "making aesthetic medicine more accessible and smart."

Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.

We aim to "make aesthetic medicine more accessible" for you.

Clinic Reception

Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo

Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo

About the physician supervision of this site

About the physician supervision of this site


This site is operated under the supervision of Smart Skin Clinic's supervising physicians.

This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.

This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.

Physician Who Supervised This Page

Kota Ishii, Chief Medical Director, Smart Skin Clinic

Smart Skin Clinic, Chief Medical Director / Physician

Kota Ishii

We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.

Interview with Director Kota Ishii

Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.