![Official] Smart Skin Clinic｜Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)
PROFILO｜Smart Skin Clinic [Official]
*Number of cases | For the period from September 1, 2023 to April 1, 2025
Free consultations at our clinic are handled directly by a physician, not by a beauty counselor.
Because of this, there is never any hard selling during a free consultation, so please book with complete peace of mind.
Before/After Profhilo Injections
What is Profhilo?
The official product name is "Profhilo®." On the market since 2015, it is a hyaluronic acid product created using the NAHYCO™ technology developed by Italy's IBSA.
A treatment that can address sagging and improve skin quality at the same time.
The conventional hyaluronic acid that most people are familiar with"cross-linked"It is a form of hyaluronic acid, andProfhilo is a "non-cross-linked" hyaluronic acid.That is the key distinction.
the major difference between cross-linked and non-cross-linked hyaluronic acid comes down to whether or not it spreads. Profhilo, a non-cross-linked hyaluronic acid, spreads out from the injection site and can be expected to deliver effects over a wide area.
Expected benefits
Profhilo can be expected to offer the following effects:
〇 Improvement of wrinkles and sagging
〇 Improvement of firmness and elasticity (enhanced, dewy skin)
〇 Lifting effect
〇 Natural volume enhancement
When can the effects be felt after treatment?
When can the effects be felt after treatment?
Dr. IshiiHow soon the effects are felt varies from person to person, but they are often felt gradually from a few days to a few weeks after the injection. The maximum effect is usually felt around one month after the injection.
How long do the effects last?
How long do the effects last?
Dr. IshiiThey are said to last from about 6 months to 1 year. For lasting results, we recommend regular injections for maintenance.
Profhilo pricing at Smart Skin Clinic
| 1 session (2cc) | 49,800 yen |
| Set of 2 (2cc x 2) | 95,600 yen (47,800 yen per vial) |
| Set of 3 (2cc x 3) | 137,400 yen (45,800 yen per vial) |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
*Profhilo uses a set of designated injection points known as the BAP technique (treatment at bio-aesthetic points), so at essentially any clinic 2cc covers the treatment area described above.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Need for anesthesia | Low
Treatment Area / Method
Profhilo isthe BAP technique (bio-aesthetic point technique)injected using this designated method.
Standardizing the injection sites is said to help achieve consistent results.
10 points each on the face or neck.
These 10 points are centered on the lower third of the face, where skin atrophy from aging tends to appear, and are locations that anatomically contain no major blood vessels or nerves.
A small, shallow amount of 0.2cc is injected per point. One vial (2cc) is used per treatment.
Facial injection sites
Neck injection sites
Injection sites on the backs of the hands
FAQ
- How often and how many times should I receive it?
- Dr. Ishii
You can expect results even after a single session, but for the most effective approach we recommend one of the following:
① Have the first and second sessions one month apart, then continue the same pattern once a year thereafter.
② Have the first and second sessions one month apart, then continue every six months thereafter. - Does it hurt?
- Dr. Ishii
It varies from person to person. We use a fine needle, but you may feel a slight pricking sensation. The center of the face is also said to be more sensitive to pain.
- How long is the downtime?
- Dr. Ishii
Redness subsides in about 24 hours.
Who cannot receive this treatment
Those who are pregnant or breastfeeding
Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy
Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders
Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin
Those with excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Profhilo injection site
Risks and Side Effects
At the needle puncture site:
Redness, swelling, pain, edema
Bruising
Temporary raised bumps
Downtime
Redness and raised bumps may occur at the injection site, but in most cases they return to normal in about 24 hours.
Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.
Treatment Flow
You can easily book from your smartphone.
A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.
During counseling, please feel free to share any concerns. Rest assured, there is no pushy sales.
After marking is done, we perform the injection while checking in with you as we go.
We explain in detail how to care for the treated area and what to keep in mind in daily life. From a prevention and maintenance standpoint, we also suggest suitable home care, such as oral medications and skincare products that can support improvement of your concerns.
Details
| Treatment Time | About 15 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | A set of 2 treatments spaced at least 6 weeks apart is recommended. After that, maintenance about once every six months is recommended. |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | Possible right after the treatment |
| Skincare | Possible right after the treatment |
| Shower | Possible from the same day |
| Pain | A slight pricking sensation when the needle is inserted. |
Legal Notices
In Japan, Profhilo is a pharmaceutical not approved by the Ministry of Health, Labour and Welfare. The pharmaceuticals and devices used in Profhilo treatment are personally imported at the discretion of our physicians. There is also no other domestically approved product with the same performance available for this treatment.
In addition, because Profhilo is an unapproved product in Japan, it is not covered by the Adverse Drug Reaction Relief System.
The drugs and medical devices used in this treatment are not approved within Japan; they are provided based on their track record of use and safety information in other countries. Specifically, Profhilo is a hyaluronic acid currently used in over 80 countries. With more than 500,000 cases reported worldwide, as well as an AMEC & AESTHETICS award, it is a hyaluronic acid whose safety and efficacy are recognized in many countries abroad.
Please refer to this page for information on medications and similar items that require caution in personal importation.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."Profhilo treatment includes procedures using medications or medical devices not approved in Japan. The medications and devices used are personally imported at the discretion of our clinic's physicians.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
We aim to "make aesthetic medicine more accessible" for you.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.