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Profhilo Injection [Smart Skin Clinic Tokyo] Yahoo!
Profhilo pricing at Smart Skin Clinic
| 1 session (2cc) | 49,800 yen |
| Set of 2 (2cc x 2) | 95,600 yen (47,800 yen per vial) |
| Set of 3 (2cc x 3) | 137,400 yen (45,800 yen per vial) |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
*Profhilo uses a set of designated injection points known as the BAP technique (treatment at bio-aesthetic points), so at essentially any clinic 2cc covers the treatment area described above.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What is Profhilo?
Its official product name is "Profhilo®." On the market since 2015, it is a hyaluronic acid product from the Italian company IBSA.
To explain it in technical terms,
it is a hybrid complex of low- and high-molecular-weight hyaluronic acid (hybrid hyaluronic acid), combining two types of hyaluronic acid — high- and low-molecular-weight — through NAHYCO Hybrid Technology.
The conventional hyaluronic acid that most people are familiar with"cross-linked"hyaluronic acid.Profhilo is a "non-cross-linked" hyaluronic acid.That is the key distinction.
The major difference between cross-linked and non-cross-linked lies in whether it spreads. Profhilo, a non-cross-linked hyaluronic acid, spreads out from the injection site to deliver its effects over a wide area.
With conventional hyaluronic acid injections, bone and fat volume lost with age was "filled in" with hyaluronic acid to refine facial contours and improve wrinkles and nasolabial folds.
It targets specific areas such as the under-eyes, nasolabial folds, and marionette lines; the injected hyaluronic acid stays within the treatment area, filling in lost fat and lifting ligaments.
Recommended if you have any of these concerns
- Sagging under the eyes
- Dark circles under the eyes
- Hollows under the eyes
- Fine lines at the corners of the eyes
- Gaunt or sagging cheeks
- Wanting to improve neck wrinkles
- Prominent tendons and wrinkles on the backs of the hands
- Wanting fast-acting results from skin treatment
Effects and how they work
In a nutshell,it "rebuilds the skin's cells.".
As a result, you can gain the following three main effects.
- Improvement of wrinkles
- Improvement of firmness and elasticity (enhanced, dewy skin)
- Lifting effect
To give a more technical explanation,
hyaluronic acid comes in low- and high-molecular-weight forms. (Different molecular weights have different biological actions.) The "NAHYCO Hybrid Technology" used in Profhilo makes it possible to loosely bond low- and high-molecular-weight hyaluronic acid. In the dermal layer of the skin, this combined complex of low- plus high-molecular-weight hyaluronic acid (hybrid hyaluronic acid)stimulates fibroblasts to produce extracellular matrix.At the same time, it also increases fat cells in the subcutaneous tissue.
Through these actions, it can improve wrinkles and sagging and plump up the skin.
The extracellular matrix is the collective term for the substances surrounding cells in the body. In the dermis,the extracellular matrix refers to collagen, elastin, and ground substance (such as hyaluronic acid).This dermal extracellular matrix is responsible for maintaining skin elasticity and retaining moisture.
With age, the extracellular matrix degenerates and deteriorates. This degeneration causes the skin to lose elasticity, become thinner, and lose moisture. As a result, the skin loses firmness and shows signs such as sagging and fine lines.
efficacy
Profhilo contains no chemicals or biological agents whatsoever.
Therefore,it is less likely to cause allergic reactions and the like.This is one of its characteristics.
Also,The efficacy of Profhilo has also been noted in several published papers.
Based on three years of post-market experience, the efficacy profile of the medical device in this study is favorable
Daniel Cassuto, et al. (2020) Safety Assessment of High- and Low-Molecular-Weight Hyaluronans (Profhilo®) as Derived from Worldwide Postmarketing Data. Biomed Res Int.
Profhilo at Smart Skin Clinic
We use "Profhilo®."
As of 2020,it has been introduced in more than 80 countriesIt is a hyaluronic acid with over 500,000 cases reported worldwide, and it has also won AMEC & AESTHETICS awards.
Who cannot receive this treatment
Those who are pregnant or breastfeeding
Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy
Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders
Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin
Those with excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Profhilo injection site
Risks and Side Effects
At the needle puncture site:
Redness, swelling, pain, edema
Bruising
Temporary raised bumps
Downtime
Redness and raised bumps may occur at the injection site, but in most cases they return to normal in about 24 hours.
Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.
Treatment Flow
You can book from your smartphone.
A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.
During counseling, please feel free to share any concerns. Rest assured, there is no pushy sales.
After marking is done, we perform the injection while checking in with you as we go.
We will provide detailed instructions on how to care for the treated area and what to keep in mind in your daily life.
In addition, with a focus on prevention and maintenance, we recommend appropriate home care products—such as oral medications and skincare products—that can help alleviate your concerns.
Details
| Treatment Time | About 15 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | ・It is recommended to wait at least 6 weeks and undergo the treatment as a two-session set. ・After that, maintenance treatment is recommended about once every six months. |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | Possible right after the treatment |
| Skincare | Possible right after the treatment |
| Shower | Possible from the same day |
| Pain | A slight pricking sensation when the needle is inserted. |
FAQ
- How often and how many times should I receive it?
Dr. IshiiA single session may be effective, but as more effective approaches we recommend one of the following.
① Have the first and second sessions one month apart, then continue the same pattern once a year thereafter.
② Have the first and second sessions one month apart, then continue every six months thereafter.
*Through Profhilo's skin-remodeling effect, the extracellular matrix increases and skin recovery is encouraged. Without maintenance, once treatment reaches its peak, the extracellular matrix gradually declines "with aging." For this reason, we recommend the approach above.- Does it hurt?
- Dr. Ishii
It varies from person to person. We use a fine needle, but you may feel a slight pricking sensation. The center of the face is also said to be more sensitive to pain.
- How long is the downtime?
- Dr. Ishii
Redness often subsides within about 24 hours.
Legal Notices
In Japan, Profhilo is a pharmaceutical not approved by the Ministry of Health, Labour and Welfare. The pharmaceuticals and devices used in Profhilo treatment are personally imported at the discretion of our physicians. There is also no other domestically approved product with the same performance available for this treatment.
In addition, because Profhilo is an unapproved product in Japan, it is not covered by the Adverse Drug Reaction Relief System.
Please refer to this page for information on medications and similar items that require caution in personal importation.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."
Launched in Italy in 2015, the Profhilo procedure has been recognized for its wide-ranging effects and is now offered in more than 80 countries worldwide.
In addition, more than 500,000 cases have been reported to date, and it has also received the AMEC & AESTHETICS award (a prominent international award).
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.
We aim to "make aesthetic medicine more accessible" for you.
Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.