Pullreal Injection [Smart Skin Clinic] Yahoo!
Our free consultations are conducted by a physician. Please feel free to ask about whether a treatment is right for you or about anything you're unsure of. We do not engage in sales-oriented solicitation.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
What is the Pluryal (PLURYAL) Densifier series?
The Pluryal Densify series is an injectable formulation containing polynucleotides (PN) and other ingredients. It was developed by MD Skin Solutions (Luxembourg) and is used at medical institutions overseas.
*In Japan, it is classified as an unapproved pharmaceutical product.
- Pluryal Silk (PLURYAL SILK)
- Pluryal Densify (PLURYAL DENSIFY)
- Pluryal Biosculpture (PLURYAL BIOSCULPTURE)
- Pluryal Hair Density (PLURYAL HAIR DENSITY)
Each formulation is used according to the injection site and purpose. Details will be explained during your consultation.
Main Ingredients
The main ingredient is salmon-derived polynucleotides (PN). Some formulations also contain non-cross-linked hyaluronic acid, mannitol, and other ingredients.
Fees (tax included; private treatment)
Silk (manual injection by a physician)
| 1 session (1 bottle, 2cc) | 44,800 yen |
| 3 sets | 119,400 yen (per session39,800 yen) |
| 4 sets | 155,200 yen (per session38,800 yen) |
Densify (Water Light Injection treatment)
| 1 bottle (2cc) | |
|---|---|
| Once | 49,800 yen |
| 3 sets | 146,400 yen (per session48,800yen) |
| 4 sets | 191,200 (per session47,800yen) |
| 2 bottles (4cc) | |
|---|---|
| Once | 69,800 yen |
| 3 sets | 194,400 yen (per session64,800yen) |
| 4 sets | 255,200 yen (per session63,800yen) |
| 3 bottles (6cc) | |
|---|---|
| Once | 101,800 yen |
| 3 sets | 302,400 yen (per session100,800 yen) |
| 4 sets | 399,200 yen (per session99,800 yen) |
- For easier comparison with other clinics' listings, we also offer a "3cc" option.
- That said, for the whole face (full face), 3cc does not provide sufficient "density," so if you are seeking the maximum effect, we suggest using the following as a guide when choosing.
- [Pattern 1] Lighter treatment is fine for the forehead and the area below the nose ⇒ 3cc
- [Pattern 2] The area below the nose can be a little lighter, but I want thorough treatment above the nose ⇒ 4cc
- [Pattern 3] I want thorough treatment across the whole face, including below the nose ⇒ 6cc
- If you are unsure, the physician will confirm your wishes on the day and suggest the optimal volume (please rest assured that we never upsell unnecessarily).



Hair Density (Water Light Injection treatment)
| 1 bottle (2cc) | |
|---|---|
| Once | 49,800 yen |
| 3 sets | 146,400 yen (per session48,800yen) |
| Set of 5 sessions | 234,000 yen (per session46,800yen) |
| Set of 10 sessions | 428,000 yen (per session42,800 yen) |
| 2 bottles (4cc) | |
|---|---|
| Once | 79,800 yen |
| 3 sets | 236,400 yen (per session78,800yen) |
| Set of 5 sessions | 384,000 yen (per session76,800yen) |
| Set of 10 sessions | 728,000 yen (per session72,800yen) |
| 3 bottles (6cc) | |
|---|---|
| Once | 109,800 yen |
| 3 sets | 323,400 yen (per session107,800 yen) |
| Set of 5 sessions | 524,000 yen (per session104,800 yen) |
| Set of 10 sessions | 998,000 yen (per session99,800 yen) |



FAQ
Which formulation should I choose?
The appropriate formulation varies depending on your goal and the area being treated. Your physician will assess your condition, discuss your preferences, and then make a recommendation.
What are the main risks and side effects?
Redness, swelling, or bruising may occur at the injection site. These symptoms usually subside within a few days to about 14 days. Details will be explained during your consultation.
Legal Notices
This treatment is private-pay care using a pharmaceutical product not approved in Japan. Based on our physicians' judgment, we carry out personal import procedures in accordance with the Act on Pharmaceuticals and Medical Devices.
Overseas safety information: Pluryal has obtained the European CE mark.
Within Japan, it is not covered by the Relief System for Adverse Drug Reactions.
The Ministry of Health, Labour and Welfare's advisory on personal importation
Smart Skin Clinic
EX Kanda Nishikicho Building, 8th Floor, 3-16-1 Kanda Nishikicho, Chiyoda-ku, Tokyo
Supervising Physician: Smart Skin Clinic Physician
This page has been created in compliance with the Medical Advertising Guidelines.
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
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