What are the expected effects of Rejuran for dark circles and fine wrinkles under the eyes?

Does Rejuran work under the eyes?"
When can I expect to see the benefits of Rejuran for dark circles under my eyes?"

Do you have these questions about Rejuran?

Hello. I am a doctor at Smart Skin Clinic.

Rejuran is effective for a variety of skin problems, but it is also a treatment for under-eye problems.

In this issue, our cosmetic dermatology clinic will explain the effects that Rejuran can have on the under-eye area, when the effects appear, how long the effects last, suitable formulations and treatments, and how to receive effective treatment.

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What is Rejuran?

What is Rejuran, and how does it work and show its effects on under-eye concerns?

Rejuran is an injectable treatment, and the formulation is based on "polynucleotides" extracted from salmon. Polynucleotides act on the dermis layer deep in the skin to activate fibroblasts. Fibroblasts are cells that produce collagen and hyaluronic acid, which are the source of firmness and moisture. By injecting Rejelan, it is expected to bring firmness and moisture to the skin.

Rejuran also contains astaxanthin, an antioxidant 1,000 times more potent than vitamin E. Oxidation of the skin causes aging, leading to spots, wrinkles, and sagging. Its antioxidant effect can be expected to improve these symptoms.

How Rejuran works under the eyes

Rejelan can be expected to improve various problems under the eyes, such as fine lines and wrinkles, dryness, dark circles, and dark circles.

The skin under the eyes is thinner than any other part of the face and moves around a lot, exposing it to an environment where fine lines and wrinkles can easily form due to dryness and fatigue. In addition, the area is prone to skin problems such as blue circles due to poor blood circulation, pigmentation and brown circles due to rubbing the eye area, and black circles caused by sagging.

Rejuran can be expected to gradually restore firmness, moisture retention, and elasticity around the eyes by increasing hyaluronic acid and collagen, reduce the appearance of dark circles caused by sagging and fine lines caused by dryness, and improve blue circles by promoting capillary circulation.

The effectiveness of Rejuran injections into the periorbital area for rejuvenation, including firmness, hydration, and pore improvement, is described in the following research paper, "Comparison of polynucleotide-containing products (≒ Rejuran) and hyaluronic acid injected into the periorbital area in 27 subjects".

PATIENTS/METHODS: A total of 27 subjects were enrolled in this randomized, paired-matched, active-control study. Each subject received three PN filler injections on one side and non-cross-linked hyaluronic acid (HA) filler injections on the contralateral periorbital area, 2 weeks apart. RESULTS. Improvements in visual analog scale and global esthetic improvement scale scores were not significantly different between the PN and HA groups. The rate of improvement in skin elasticity and hydration decreased over time in both groups, with a higher rate of improvement in the PN group. The improvement rate of skin roughness and pore volume was higher in the PN group than in the HA group. There was no significant difference in the improvement rate of dermal density between the two groups.

Ye Jin Lee, Hak Tae Kim, You Jin Lee, Seung Hwan Paik, Young Seon Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Joon Min Jung, Chong Hyun Won. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial. The Journal of dermatological treatment. 2022 Feb;33(1);254-260. doi: 10.1080/09546634.2020.1748857.

When will Rejuran be effective under the eyes?

The effects of Rejuran will be difficult to feel after just one treatment. Repeated treatments will make it easier to feel the effects. The recommended number of treatments is three to four, spaced about three weeks apart.

Duration of effect of Rejuran under the eyes

The effects of Rejuran on the under-eye area will essentially last for a year or more.

Injection stimulates fibroblasts to produce collagen, elastin, and hyaluronic acid on their own. Even the best treatment will be less effective if lifestyle habits and aftercare are neglected.

I recommend "Rejuran i (Rejuran Eye)" for under eyes.

Rejuran has a formulation called "Rejuran i" suitable for under the eyes.

There are four different formulations of Rejuran for different purposes, each with different amounts of ingredients, hardness, effectiveness, and degree of pain. The formulations called "Rejuran (Healer)" and "Rejuran HB" can be used for the entire face.

However, if you are particularly concerned about the area around the eyes, we recommend that you choose Rejuran i, which is not as painful as Rejuran (Healer) and whose hardness and absorption rate are suitable for the eye area. Since it is soft and stretchy, a smooth and natural finish without discomfort can be expected even when injected into the thin skin around the eyes.

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How to treat under eyes with Rejuran

The flow of Rejuran treatment is as follows

  • Cleanse and wash face to clean the treatment area.
  • Cooling and surface anesthesia to alleviate needle pain
  • Injection while checking for pain

I recommend "doctor's hand" for rejuran under the eyes.

There are three treatment methods for Rejuran: (1) manual injection by a doctor, (2) water light injection, and (3) dermapen.

Manual injection by a physician" is recommended for treating a narrow area under the eyes. Manual injection allows for fine adjustment of "injection depth," "injection volume," and "injection density," and thus has the advantage of allowing for a more personalized approach for each patient. In this case, it is important to choose a clinic with a high level of skill. Check the results with case photos in advance.

Downtime, side effects, and risks of Rejuran under the eyes

Rejuran is a treatment with relatively few side effects and risks.

Downtime of Rejuran under the eyes

Downtime for Rejuran is relatively mild, lasting only a few days.

Pain and swelling will subside in a few days. If internal bleeding appears, it will take 10 to 14 days to disappear, but it can be covered with makeup such as foundation and concealer for daily life. Makeup can be applied after 24 hours.

Risk of fish allergy.

Since Rejuran uses ingredients extracted from salmon, people who are allergic to fish should be careful. The risk of allergic reactions to Rejuran also makes it inadvisable for them to undergo treatment.

Pain during injection can be alleviated with anesthesia.

Because Rejuran is an injectable treatment, it causes a prickling pain when the needle pricks the skin. Rejuran is said to be more painful than other injectable products. However, it is "Rejuran (Healer)" that is more painful, and the pain of "Rejuran i" is about the same as other injection treatments.

Cooling and surface anesthesia prior to the procedure will alleviate pain during injection.

If swelling and pain increase, infection is possible.

Downtime symptoms of Rejuran will gradually subside over time.

If it takes time for the pain and swelling to resolve, you may have an infection. Please contact the clinic immediately. If you have any other symptoms of concern, please consult the clinic.

Maximize effectiveness with regular treatment intervals.

Rejuran will be more effective with repeated treatments.

Regardless of the area, the recommended number and frequency of treatments is 3 to 4 sessions, spaced about 3 weeks apart. After that, maintenance is recommended once every six months to a year.

Difference from hyaluronic acid injections

Hyaluronic acid injections are a treatment that physically increases volume. Although the effects can be felt immediately, the preparation is gradually absorbed into the body. In addition, hyaluronic acid suitable for the eye area is particularly easily absorbed, so the effect lasts only about six months.

On the other hand, Rejelan is a treatment that improves the patient's own skin through its own regenerative power. Although the effect is not immediate, it is gradual, and the natural look lasts longer.

Go to Smart Skin Clinic for under eye rejurant.

Have your questions been answered about Rejuran under the eyes?

Rejelan is a formulation suitable for various problems around the eyes, such as wrinkles, sagging and dark circles under the eyes. In particular, Rejuran i is specially designed for the eye area and offers natural-looking results. When undergoing treatment, choose a clinic you can trust and have the procedure performed at appropriate intervals.

Smart Skin Clinic offers free consultations. If you suffer from dark circles, sagging skin under the eyes, or wrinkles, please feel free to contact us for a consultation.

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In addition, our clinic has the following "particulars" in injections of Rejuran and other products.

Reference

Ye Jin Lee, Hak Tae Kim, You Jin Lee, Seung Hwan Paik, Young Seon Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Joon Min Jung, Chong Hyun Won. Comparison of the effects of polynucleotide and hyaluronic acid fillers on periocular rejuvenation: a randomized, double-blind, split-face trial. The Journal of dermatological treatment. 2022 Feb;33(1);254-260. doi: 10.1080/09546634.2020.1748857.

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