JalPro Japan's lowest level 3cc 39,800 yen (47%off) [Smart Skin Clinic

At our clinic, the free consultation is handled directly by a specialist physician, not by a beauty counselor as at major clinics. For this reason, there is no hard selling whatsoever during the free consultation, which has made it very well received even by patients who are new to aesthetic treatments. Please book with peace of mind.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Jalupro Super Hydro at one of the lowest price levels in Japan
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| Sessions (2.5 cc) | twice | Per 1 cc Price |
|---|---|---|
| Once | 49,800 yen | 23,900 yen |
| 2 sessions | 95,600 yen (47,800 yen per session) | ¥19,120 |
| 3 times | 137,400 yen (¥45,800 per session) | ¥18,320 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Jalupro (Classic, HMW) at one of the lowest price levels in Japan
Jalupro Classic (manual injection by a doctor)
| 3cc | Price | Per 1 cc Price |
| 1 bottle | 39,800 yen | 13,270 yen |
| 4 bottles | 139,200 yen (34,800 yen per session) | 11,600 yen |
Jalupro HMW (manual injection by a doctor)
| 3cc | Price | Per 1 cc Price |
| 1 bottle | 59,800 yen | 19,930 yen |
| 3 bottles | 173,400 yen (per session 57,800 yen) | 19,270 yen |
| 4 bottles | 227,200 yen (per session 56,800 yen) | 18,900 yen |
Jalupro Classic Water Light Injection (mechanical injection)
| 3cc | Price | Per 1 cc Price |
|---|---|---|
| Once | 29,800 yen | ¥9,933 |
| 4 sessions | 107,200 yen (¥26,800 per session) | ¥8,933 |
| 6cc | Price | Per 1 cc Price |
|---|---|---|
| Once | 47,880 yen | 7,980 yen |
| 4 sessions | 179,520 yen (per session44,¥880) | 7,480 yen |
Need for Anesthesia | High
Prices shown are all-inclusive, covering anesthesia and other fees.
This is because anesthesia is recommended for this treatment, so the standard practice is to perform it after applying anesthetic cream or administering local anesthesia.
Why we can deliver both "high quality" and "some of the lowest prices in the nation"The reasons we can achieve this
In fact, more than 90% of aesthetic clinics carry too many unnecessary costs to offer their patients the best possible price.
Guided by this awareness of the problem, we created an aesthetic clinic completely unlike the conventional norm.
(1) Areas with low rent
(2) Cutting back on lavish interiors
(3) Cutting back on excess staffing
(4) Cutting back on excessive advertising spend
This is how we deliver something other clinics can't match: the "High-quality Jalupro injections offered at one of the lowest price levels in Japan" we're able to achieve.
Some patients are also concerned about whether a formulation is genuine, given the low price.
To ease such concerns,we open a brand-new formulation on the spot and show it to you,which gives our patients peace of mind.

Smart Skin Clinic's Profhilo consistently earns high ratings in reviews on Google, Hot Pepper, KireiPass, and more
At Smart Skin Clinic, we think carefully about what our patients truly need and thoroughly cut out unnecessary costs, allowing us to deliver affordability, high quality, and high satisfaction all at once.
As a result,we earn high ratings across a variety of review sites, including Google and Hot Pepper Beauty.we have earned.
As a result, about 80% of those who visit us once return for repeat treatment.
Google review rating 4.5/5.0 (97 reviews)

Hot Pepper Beauty rating 4.57/5.00

KireiPass rating4.30/5.00

Kumapon rating4.71/5.00

Gangnam Unni rating9.3/10.0

What is Jalupro?

An injectable preparation made of non-cross-linked hyaluronic acid + amino acids + peptides
Because it contains high concentrations of both low- and high-molecular-weight hyaluronic acid, the low-molecular-weight hyaluronic acid enhances immediate results and hydration, while the high-molecular-weight hyaluronic acid strengthens the scaffolding for the moisturizing effect and helps it last longer. In this way, by strengthening and regenerating the ligaments, it increases density and helps restore the skin's elasticity.
Through the action of amino acids, it activates fibroblasts and promotes the production of collagen and elastin, remodeling the skin to improve natural firmness and fine lines. In particular, Jalupro contains a high concentration—50%—of "glycine," which supports collagen production.
The peptides contain growth factors and moisturizing factors. The "growth factors" actively generate new skin cells, helping to improve and prevent wrinkles and to support wound healing. The "moisturizing factors" enhance skin texture and clarity.
An ECM preparation—a type of injectable known as a collagen booster
ECM preparations are drugs that act on the ECM (Extracellular Matrix) to improve the condition of the skin. In addition to Jalupro, ECM preparations include Profhilo and Sunekos. Even among ECM preparations, the ingredients differ, so the effects you can expect differ as well.
Milan Injection
It is also called the "Milan Injection" because its manufacturing plant is located in Milan, Italy.
It is a hyaluronic acid–based collagen booster developed by the Swiss biotechnology company "Professional Derma." Three types of Jalupro are currently available.
It has been in use since 2005 and has a track record of more than 1 million cases.
Three types of Jalupro
- Classic
- HMW
- Superhydro
1. Classic

- Ingredients:
Low-molecular-weight hyaluronic acid + 4 amino acids - Injection site:
Fine lines at the corners of the eyes, dark circles under the eyes, around the eyes, forehead, neck - Expected effects:
Dark circles around the eyes, wrinkles at the corners of the eyes, improvement of acne scars, improvement of pigmentation, strong antioxidant action, fine wrinkles, wrinkle prevention, skin maintenance, improvement of scars after surgery - Recommended number of sessions:
4 sessions in total, spaced 1 to 2 weeks apart. After that, once every 6 to 9 months.
②HMW (High Molecular Weight)

- Ingredients:
High-molecular-weight hyaluronic acid + 4 amino acids. HMW (High Molecular Weight) means high molecular weight. - Effect:
Deeply etched wrinkles. Effective for natural aging care, especially for those with thin skin or little subcutaneous fat. High-molecular-weight hyaluronic acid can hold more water, moisturizing the skin and providing a long-lasting hydrating effect. It is often used to form a film on the skin's surface to protect it from dryness. - Injection site:
Mid-face to lower face. As a guide, injecting 9 spots on one side—18 spots on both sides combined—allows it to penetrate over several hours to a day, taking effect across the entire area from the eyes downward.
Superhydro

- Overview:
An injectable preparation designed to regenerate the retinacula cutis (RC)—that is, the ligaments. For this reason, it is also"a tightening injection."as it is also called. Ligaments, like the branches of a tree, spread in all directions through the layers of subcutaneous tissue and support the skin. - Ingredients:
It contains "7 amino acids," "3 peptides," and "80mg/2.5ml of low-/high-molecular-weight hyaluronic acid." Hyaluronic acid of different sizes—from low to medium to high molecular weight—is combined. Low-molecular-weight hyaluronic acid penetrates easily into the deeper layers of the skin, while high-molecular-weight hyaluronic acid is effective at retaining moisture on the surface. This combination of hyaluronic acids is designed to provide a multifaceted moisturizing and therapeutic effect on the skin.- [7 amino acids] Glycine, proline, lysine, leucine, alanine, valine, arginine
- [3 peptides] Acetyl decapeptide-3, oligopeptide-24, acetyl tetrapeptide
- [Hyaluronic acid of two molecular weights] Low molecular weight: 200kDa, high molecular weight: 2000kDa
- Effect:
Strengthens and regenerates ligaments, lifts, remodels subcutaneous tissue, and offers a high moisturizing effect—particularly effective for tightening the skin of the mid-face - Injection site:
Predetermined. One side of the face: 6 to 7 spots, one side of the neck: 6 spots - Recommended number of sessions:
It is best to do a set of 2 sessions within one month. Once the skin is in good condition, we recommend a treatment about once every 6 months for maintenance. - Other:
Launched in 2021
Click here for details on Jalupro Super Hydro.
Case photos (before/after)



Recommended if you have any of these concerns
- I want to aim for a natural improvement
- dark circles under the eyes
- Wrinkles at the corners of the eyes, crepe-like fine lines
- I want firmness and radiance
- Hollow cheeks
- I want firmness and radiance in my cheeks
- neck wrinkles
- Sagging of the face and cheeks
- I want to lift and firm
- Nasolabial folds
Effects & benefits
[Effect]
Within the skin, Jaluproremodeling of the extracellular matrix (ECM)promotes this, which delivers a range of benefits.
Remodeling of the extracellular matrix is the action of repairing and reactivating collagen and elastin in aging skin.
Young skin has many fibroblasts, and as these fibroblasts work actively, collagen and elastin are metabolized smoothly, keeping the skin healthy, firm, and elastic. In aging skin, on the other hand, fibroblasts decrease and collagen and elastin decline, leading to wrinkles and sagging.
By replenishing fibroblasts with amino acids, Jalupro activates fibroblast activity, boosts the production of collagen and elastin, and remodels the extracellular matrix (ECM).
After injection, the effect of the hyaluronic acid appears within a few days, while the effect of the amino acids appears gradually over 6 months, starting about 1 month later.
[Benefits]
・Improved skin hydration:
Jalupro enhances the skin's ability to retain moisture, leaving it hydrated and plump.
・Reduced fine lines:
By promoting collagen production and refining skin texture, it makes wrinkles and fine lines less noticeable.
・Improved skin tone and texture:
It improves overall skin texture and evens out skin tone, making the skin look smoother and brighter.
・Minimal downtime:
Non-invasive Jalupro treatment involves little to no downtime, so you can resume daily life right away.
・Versatility:
Jalupro can be used not only on the face but also on various parts of the body, making it well suited to addressing concerns in multiple areas.
・Natural finish:
It provides a natural appearance without looking artificial.
Safety
Because Jalupro contains no cross-linking agents,it can be considered highly safe..
Specifically,it is less likely to cause allergic reactions or emboliThat is the point.
The reason for this is that Jalupro does not contain a "cross-linking agent."
Cross-linking agents may cause allergic reactions, immune reactions, and inflammation. Although very infrequent, allergic reactions have been reported. Conventional hyaluronic acid injectables contain a substance called a cross-linking agent.
It is the creation of new chemical bonds that bridge chain-like strands of hyaluronic acid together. As a result of cross-linking, hyaluronic acid takes on a three-dimensional structure. This three-dimensional structure slows the absorption and breakdown of hyaluronic acid at the injection site, giving it a longer-lasting effect.
In addition, EU regulatory authorities recognize Jalupro's therapeutic efficacy and safety. Jalupro has received the CE Mark, which indicates compliance with European standards and safety requirements for medical products.
Who cannot receive this treatment
Those who are pregnant or breastfeeding
Those with abnormal immune function or a history of it, and those undergoing immunosuppressive therapy
Those prone to keloid formation, hypertrophic scarring, or pigmentation disorders
Those with a bleeding tendency, or those taking non-steroidal anti-inflammatory drugs such as aspirin or anticoagulants such as warfarin
・Those with excessive sunburn, eczema, dermatitis, severely inflamed acne, or scabs at the Jalupro injection site
Risks and Side Effects
At the needle puncture site:
Redness, swelling, pain, edema
Bruising
Temporary raised bumps
Downtime
Redness and raised bumps may occur at the injection site, but in most cases they return to normal in about 24 hours.
Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, though not always. If bruising occurs, it gradually fades over 10 to 14 days.
Treatment Flow
You can easily book from your smartphone.
A smart, effortless check-in: just give your name and our clinic IT system completes reception right away.
During counseling, please feel free to share any concerns. Rest assured, there is no pushy sales.
After marking is done, we perform the injection while checking in with you as we go.
We explain in detail how to care for the treated area and what to keep in mind in daily life. From a prevention and maintenance standpoint, we also suggest suitable home care, such as oral medications and skincare products that can support improvement of your concerns.
Details
| Treatment Time | About 20 to 30 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | [Classic / HMW] ・A set of 4 sessions, spaced 1 to 2 weeks apart, is recommended. ・After that, maintenance about once every 6 to 9 months is recommended. [Super Hydro] ・A set of 2 sessions, spaced 2 weeks apart, is recommended. ・After that, maintenance about once every 6 to 9 months is recommended. |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | Possible right after the treatment |
| Skincare | Possible right after the treatment |
| Shower | Possible from the same day |
| Pain | If topical anesthesia is applied, the stinging pain of the needle prick is reduced. There is little pain while the drug is being injected. |
FAQ
- How often and how many times should I receive it?
Dr. IshiiEven a single session can be effective, but as the most effective approach, we recommend one of the following for each preparation.
[Classic / HMW]
・A set of 4 sessions, spaced 1 to 2 weeks apart
・After that, maintenance about once every 6 to 9 months
[Super Hydro]
・A set of 2 sessions, spaced 2 weeks apart
・After that, maintenance about once every 6 to 9 months
*Through Jalupro's skin-remodeling effect, the extracellular matrix increases and the skin is rejuvenated. Without maintenance, once treatment reaches its peak the extracellular matrix will gradually decrease "due to aging." For this reason, we recommend the approach above.- Does it hurt?
Dr. IshiiIt varies from person to person. We use a fine needle, but you may feel a slight pricking sensation. The center of the face is also said to be more sensitive to pain.
- How long is the downtime?
Dr. IshiiRedness subsides in about 24 hours.
Introducing other injectable treatments at Smart Skin Clinic for those with skin-quality concerns
In addition to Jalupro, Smart Skin Clinic offers other injection treatments effective for improving skin quality.


If you are interested in Juvelook treatment, please see the link below.
Legal Notices
Jalupro treatment involves the use of drugs or medical devices not approved in Japan. The drugs and devices used in the treatment are personally imported under the judgment of our clinic's physicians.
Please refer to this page for information on medications and similar items that require caution in personal importation.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.
We aim to "make aesthetic medicine more accessible" for you.
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
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