Juvelook injection

*Number of cases|From December 1, 2023 to September 1, 2024

JUVELOOK is a skin booster formulation that has become very popular in Korea since 2023, and an increasing number of clinics in Japan have been handling it since the latter half of 2023. Smart Skin Clinic will explain such a popular formulation in detail. The price at our clinic is also described, so please check it out if you are interested in the treatment.

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What is Juvelook?

Jubeluk Product Images

JUVELUX is a non-cross-linked hyaluronic acid andPDLLA (Poly-DL-lactic acid)This is a type of injectable drug called a skin booster, which is a combination of

After injection, it is slowly absorbed into the body over a period of one to two years, during which time it stimulates fibroblasts to naturally increase collagen and elastin, and a lasting effect can be expected.

Since it is made from lactic acid, which is also present in the human body, it is highly safe and does not cause allergies.


JUVELOOK is written in English.
This is a coined term that combines JUVE (youth, vitality, vigor) and LOOK (appearance, expression).

It is also the equivalent of Japan's Ministry of Health, Labor and Welfare.U.S. Food and Drug Administration (FDA)and ..,Approved by the Korea Food and Drug Administration (KFDA)It is a highly safe formulation.

Originating in Korea, certified by the KFDA in Korea.skin booster

Korea Consumer Awards

Jubeluk has won the award in the Korean consumer skin booster category for two consecutive years (2022,2023).

Korea Consumer Award, 2023A total of 41 brands were selected, including Starbucks, Terra and Jubeluk, at the

Jubeluk is attracting attention as the next generation skin booster of Rejelan. In Korea, it is alreadyMore than 400,000The number of people who have received the program has been (as of December 2023)

Types of Jubeluk

Although it is not well known, there are actually two types of Jubeluk. They are the following two types.

  • Juvelook
  • Jubeluk Volume-Lenisna (Lenisna)

Jubeluk of ➊ is the well-known one, so when we say "Jubeluk," you may recognize it as ➊.

Jubeluk volume of ❷ is often called "renisna" in Japan. In Korea, on the other hand, it is often called "Jubeluk volume.

Difference between Jubeluk and Jubeluk Volume (Renisna)

Difference between Jubeluk and Renisna
What is the difference between the two?
Dr. Smaski.

Concentration and particle size. This will vary in the way volume is produced. As the name suggests, JUVELUX VOLUME (RENISNA) is excellent at producing volume, so it is good at deep wrinkles, such as the laugh lines.

For more information on Jubeluk Volume (Renisna), click here.

Four characteristics of Jubeluk

(1) Longer duration of effect

Polylactic acid (PDLLA) continuously stimulates fibroblasts inside the skin. This stimulates collagen production. After injection, it is slowly broken down into water and carbon dioxide inside the skin over a period of one to two years. Therefore, unlike conventional hyaluronic acid formulations, JUVELUX is a formulation that provides skin growth over a long period of time.

Below is the official Jubeluk YouTube, which explains how Jubeluk works. (*It is in English.)

(2) Fewer side effects

Jubelq uses a drug called polylactic acid (PDLLA). Polylactic acid preparations in the same category as JUVELQ include Sculptra and MacComb.

Sculptra had sharply shaped particles that were highly irritating to surrounding cells and carried the risk of causing subcutaneous lumps.

McComb is an induction agent for potentia. The risk of subcutaneous lumps that were likely to occur with Sculptra has been greatly reduced. On the other hand, it is not approved by the Korea Food and Drug Administration (KFDA) and cannot be injected directly into the skin.

Unlike Sculptra and MacComb, Jubeluk is made so that the particles are round in shape. Therefore, there is virtually no risk of creating subcutaneous lumps. Furthermore, it has been approved by the Korea Food and Drug Administration (KFDA) and the U.S. FDA.

(iii) Customized treatment is possible with local injections

JUVELUX can be injected as a whole as well as locally. Therefore, it is possible to address not only the entire face, but also localized concerns. For example, the following localized areas can be addressed

  • Acne scars and scar indentations
  • Fine lines and sagging under the eyes
  • Nose Pores

(4) Abundant medical data

Numerous medical papers

Jubeluk is used abundantly in Korea, and there are many research papers on its efficacy and safety.

(i)Seyeon Oh,et al. Poly-D,L-Lactic Acid Stimulates Angiogenesis and Collagen Synthesis in Aged Animal Skin. Int. J. Mol. Sci. 2023, 24(9), 7986.

(2)Suk Bae Seo M.D,et al. Skin rejuvenation effect of the combined PDLLA and non cross-linked hyaluronic acid: A preliminary study.J Cosmet Dermatol. 2023;. J Cosmet Dermatol. 2023; 00:1-9.

(iii)Seyeon Oh,et al. Poly-D,L-Lactic Acid Filler Increases Extracellular Matrix by Modulating Macrophages and Adipose-Derived Stem Cells in Aged Animal Antioxidants 2023, 12(6), 1204.

As an example, the following paper mentions the efficacy of PDLA (≈Jubelq) for acne scars.

Intradermal injection of PDLA may be used as an effective treatment with fewer side effects in patients with acne scars of Fitzpatrick skin types III-IV.

Hyeong JH et al(2022). Intradermal Injection of Poly-D, L-Lactic Acid Using
Microneedle Fractional Radiofrequency for Acne Scars:An Open-Label Prospective Trial, DERMATOLOGIC SURGERY December 2022,Volume 48-12

Recommended for

  • Those who have not had satisfactory results with laser treatment.
  • Concerned about unevenness of acne scars
  • Fine lines and wrinkles under the eyes
  • I want to increase the elasticity of my skin.
  • I want to improve my pores.
  • I want to improve my skin texture
  • I'm concerned about wrinkles on my neck.

Effect

The double action of polylactic acid (PDLLA) and non-cross-linked hyaluronic acid improves skin texture from the inside, leading to firm, radiant skin.

  • Improvement of skin quality
  • Increased elasticity and luster
  • Improvement of fine lines and wrinkles
  • Pore reduction
  • Scar Improvement
  • Improvement of acne scars (hyperpigmentation, craters)

PDLLA produces collagen continuously over a period of one to two years, so long-term effects can also be expected.

Mechanism of effect (mechanism of action)

When PDLLA is injected into the dermis deep in the skin, it is gradually broken down and absorbed into water and CO2 over a period of one to two years. In the meantime, it stimulates fibroblasts in the dermis and activates the production of collagen and elastin.

Similarly, non-cross-linked hyaluronic acid activates collagen/elastin production in the dermis by stimulating fibroblasts.

JUVELUX Mechanism of Action

(Source.)Seyeon Oh,et al. Poly-D,L-Lactic Acid Stimulates Angiogenesis and Collagen Synthesis in Aged Animal Skin. Int J Mol Sci. 2023 May; 24(9): 7986.

Case study photographs (Before/After)

Jubeluk skin texture improvement case (1)
Jubeluk skin quality improvement case (2)
Jubeluk skin quality improvement case (3)

Name of treatment Jouberc injectionBefore: Before treatment, After: After 3 treatments
Treatment Details JUVELUX injection is a procedure that improves elasticity and firmness by injecting ingredients that moisturize the skin directly into the dermal layer. It is expected to be effective in improving acne scars (craters), fine lines and wrinkles, and dry skin, and leads the entire skin to a healthy and fresh state. It promotes collagen production and aims for total care of skin texture.

Duration and number of treatments Usually 3 times at 1 month intervals is a course.
Major Risks and Side Effects Temporary redness, swelling, and internal bleeding may occur after injection, but usually improves within a few days. Mild pain or discomfort may be felt at the treatment site, but will be relieved with proper care. Allergic reactions may occur in rare cases, and effects may vary from person to person.
Price of treatment 31,980 - 79,980 yen (per treatment) *The range of prices is due to the treatment method (doctor's manual injection or water light injection) and multiple dosage plans.

Acne scars (craters)

Name of treatment JUVELEC injection: Before Before treatment, After after 3 treatments
Treatment Details JUVELUX injection is a procedure that improves elasticity and firmness by injecting ingredients that moisturize the skin directly into the dermal layer. It is expected to be effective in improving acne scars (craters), fine lines and wrinkles, and dry skin, and leads the entire skin to a healthy and fresh state. It promotes collagen production and aims for total care of skin texture.

Duration and number of treatments Usually 3 times at 1 month intervals is a course.
Major Risks and Side Effects Temporary redness, swelling, and internal bleeding may occur after injection, but usually improves within a few days. Mild pain or discomfort may be felt at the treatment site, but will be relieved with proper care. Allergic reactions may occur in rare cases, and effects may vary from person to person.
Price of treatment 31,980 - 79,980 yen (per treatment) *The range of prices is due to the treatment method (doctor's manual injection or water light injection) and multiple dosage plans.

Acne scar (crater) Jubeluk case 1
Acne scar (crater) Jubeluk case 2
Acne scar (crater) Jubeluk case (3)

(Source.)Juvelook Official

Treatmentpart

There are two major treatment areas.

(1) All faces

In full-face injections, injections are spread over the entire face, forehead, and cheeks. It is expected to be effective in pore treatment and skin texture improvement.

(2) Local

Injections are pinpointed to the wrinkles between the eyebrows, fine lines around the eyes, and acne scars. This treatment is recommended for areas of particular concern.

Treatment Method

There are three main injection methods for JUVELUX.

  • Doctor's handshake
  • Water light injection (mechanical injection)
  • potenza

➊ doctor's hand slap

The physician will check the skin condition and perform the injection at the appropriate depth and dosage for each area. Injection is performed using a syringe.

❷ Water light injections (mechanical injection)

Although the term "water-light injection" is sometimes used as the name of a drug or preparation, it is more often used as the name of a "machine".

Once the drug is set in the water-light injection machine and the depth of injection and the dosage per injection are set by the machine, it can continue to be injected at a fixed depth and dosage. In the case of water-light injections, a nurse performs the procedure.

➌ Potenza

Potenza is a type of treatment machine called microneedle RF. It is sometimes called an advanced version of the dermapen.

After the ultra-fine needle is inserted, RF waves (radio waves) are emitted from the tip of the needle. A hole is made in the skin, and the formulation (JUVELUX) is injected into the hole using a system called a "drug delivery system".

Advantages/Disadvantages

Advantages

The advantage of JUVELUX is that in addition to various skin improvement effects such as firmness and craters, PDLLA can provide long-term skin texture improvement for 1~2 years.

Demerit

Jubeluk has no major disadvantages, but the following article provides a detailed description of some minor disadvantages.

Those who cannot be treated

Pregnant or nursing mothers

Those with abnormal immune function or a history of such abnormality, and those undergoing immunosuppressive therapy.

Those prone to keloid formation, hypertrophic scars and hyperpigmentation

Those with bleeding tendency or using non-steroidal anti-inflammatory analgesics such as aspirin or anticoagulants such as warfarin

Excessive sunburn, eczema, dermatitis, acne with severe inflammation, or scabs at the site of JUVELUX injection

Risks and Side Effects

of the needle puncture site.

Redness, swelling, pain, edema

Intravascular hemorrhage

Temporary protuberance

Down time

Redness and bumps at the injection site may occur, but in most cases will return to normal in about 24 hours.

Due to the nature of the treatment, subcutaneous bleeding may occur at the needle puncture site, although not always. If subcutaneous bleeding spots occur, they will gradually disappear over a period of 10-14 days.

Charge

Our cc breakdown of JubelqOfficial dissolution method of Jubeluk.

This information is provided because we often receive inquiries about it.
Our "cc notation" for JUVELUX is the cc notation for JUVELUX created using the official dissolution method of the JUVELUX formulation.
What this means is that the drug JUVELQ is not used as-is, but is usually dissolved in saline in the proportions prescribed by JUVELQ, then mixed thoroughly, and then the dissolved JUVELQ is used.

Water light injection (mechanical injection)

3cc
Once36,800 yen
3 sets95,940 yen
(per time)31,980 yen)
4cc
Once44,980 yen
3 sets119,400 yen
(per time)39,800 yen)
*Converted to 3 cc:
per session29,850 yenbe proportionate toPrice of
6cc
Once54,980 yen
3 sets146,640 yen
(per time)48,880 yen)
*Converted to 3 cc:
per session24,440 yenbe proportionate toPrice of
Price per 3cc for each plan
plan Actual price (per set of 3 sessions) 3cc equivalent price (per transaction) Difference from 3cc plan
3cc 31,980 yen 31,980 yen
4cc 39,800 yen 29,850 yen equivalent Save 2,130 yen
6cc 48,880 yen 24,440 yen equivalent Save 7,540 yen

Need for anesthesia|High

Prices are all-inclusive, including the cost of anesthesia.
This is because anesthesia is recommended for this procedure, and it is basically standard to perform it after implementing cream anesthesia and local anesthesia.

There will be no upsells other than those indicated in the price listings on the day of the event.

Reference] How to choose the dosage (cc)

JUVELUX dosage guidelines (1)
JUVELEC dosage guidelines (2)
JUVELUX dosage guidelines (3)
Explanation of how to select dosage (cc)
  • We also offer "3cc" for easy consideration in accordance with the notation of other hospitals.
  • On the other hand, 3cc is not enough for the whole face (full face), so if you want the maximum effect, please refer to the following for your choice
  • Pattern 1] The forehead and the area from the nose down can be lighter ⇒ 3cc
  • Pattern 2] The area from the nose down can be lightened a little, but from the nose up, it should be done firmly ⇒ 4cc
  • Pattern (3)] The entire face, including the nose and below the nose, should be done thoroughly ⇒ 6cc
  • If you are not sure, the doctor will confirm your request on the same day and suggest the optimal volume (please be assured that we never upsell unnecessarily).

doctor's help

3cc
Once51,800 yen
3 sets140,940 yen
(per time)46,980 yen)
Monitor price (3 sets)129,800 yen
4cc
Once64,800 yen
3 sets179,820 yen
(per time)59,940 yen)
Monitor price
(Set 3 times)
169,820 yen
6cc
Once93,800 yen
3 sets266,940 yen
(per time)88,980 yen)
Monitor price
(Set 3 times)
256,940 yen

*Some rates have been revised effective December 5, 2024.
*For customers who made reservations on or before December 5, the rate in effect at the time of reservation will be applied.

Need for anesthesia|High

Prices are all-inclusive, including the cost of anesthesia.
This is because anesthesia is recommended for this procedure, and it is basically standard to perform it after implementing cream anesthesia and local anesthesia.

There will be no upsells other than those indicated in the price listings on the day of the event.

FAQ

When will it be effective?
Dr. Smaski.

The effect is often felt after two to three weeks.

You can get the effect once, but after receiving a set of three times, it is easy to feel a big change.

The following methods are also recommended as effective
Maintenance: 3 sets of 3 sessions at 1-month intervals, then every 6 months to 1 year.

*JUVELUX allows for sustained collagen production, resulting in long-lasting effects.

Is it safe?
Dr. Smaski.

JUVELUX is approved by the U.S. FDA and the Korean KFDA and is safe.

How is it different from hyaluronic acid treatment?
Dr. Smaski.

Hyaluronic acid therapy involves injecting cross-linked hyaluronic acid, which is a hard hyaluronic acid. This improves wrinkles by physically increasing volume. JUVELUX, on the other hand, increases collagen, which is produced by the body itself, thereby increasing natural volume.

Flow of treatment

STEP
Reservation

You can easily make reservations with your mobile phone.

STEP
Reception (desk)

This is a "smart" and easy receptionist service that can be completed immediately by the clinic's IT system by simply providing your name.

STEP
Counseling and medical examination

Please feel free to discuss any concerns you may have during the counseling session. Please be assured that there is no pushy sales.

STEP
Jubeluk injection

After the marking is carried out, the injection is carried out while talking to the patient.

STEP
After-sales service

We will explain in detail about the care of the treated area and precautions for daily life. We also suggest appropriate home care from the viewpoint of prevention and maintenance, such as oral medicines and skin care cosmetics that can be expected to improve your problems.

STEP
Returning home

More Information

Treatment Time30~40 minutes (not including counseling)
Recommended number and frequency of treatmentsIt is recommended that the program be performed in sets of three times at one-month intervals.
After that, maintenance is recommended every 6 months to a year.
Down timeAbout 24 hours
Treatment on the day of counselingPossible
MakePossible immediately after the treatment
Skin carePossible immediately after the treatment
ShowerPossible from the same day
PainThere is a stinging pain when the needle is inserted.
*There are individual differences.

Legal description

JUVELUX treatment includes the use of drugs or medical devices that are not approved in Japan. The drugs and devices used in the treatment have been imported on a personal import basis at the discretion of our physicians.

Please refer to this page for information on medicines, etc. that should be noted for personal importation.
Ministry of Health, Labour and Welfare, "Medicines, etc. that Require Caution in Personal Importation".

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Smart Skin Clinic

Smart Skin Clinic

The concept of the clinic is to "make cosmetic medicine more accessible and smart. is the concept of the clinic.

Instead of eliminating ornate interiors to reduce interior design costs and installing equipment in the dark, we carefully select the equipment we need and reduce the cost of the equipment.

We aim to "make cosmetic medicine more accessible" for you.

Clinic Reception

Address: 8F EX Kanda Nishiki-cho Building, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic Dermatology (aesthetic dermatology, medical hair removal, medical slimming)

Address: 8F EX Kanda Nishiki-cho Building, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic Dermatology (aesthetic dermatology, medical hair removal, medical slimming)

About the physician supervision of this site

About the physician supervision of this site


This site is operated under the supervision of the Smart Skin Clinic supervising physicians.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.

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