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PRP Regeneration Therapy for Labia Majora Lasts 5 Times Longer than Hyaluronic Acid｜Smart Skin Clinic
Lasts 5x Longer Than Hyaluronic Acid! Labia Majora PRP Injection
20% OFF Campaign Now Running
*All prices shown include tax. *Self-pay treatment (not covered by insurance). *Consultation and needle fees included. No upsells on the day.
Loss of volume, sagging, or wrinkling of the labia majora —
Are you concerned about it?
With aging, childbirth, or rapid weight loss,it is not uncommon for the labia majora to lose firmness and elasticity.When the labia majora lose volume, it's not just a change in appearance —many women also experience discomfort from the labia minora becoming exposedand rubbing against underwear.
As a volumizing treatment for the labia majora,Hyaluronic acid injectionis the common option,but its effects typically last only six months to a year,which is relatively short and requires regular re-injections.
Our clinic'sPersonalized PRP Injectionuses growth factors extracted from your own blood,Regenerative Medicine.offering long-lasting results of 4 to 5 yearsand, because it uses your own tissue,carries almost no risk of a foreign-body reaction..
In this article,Ministry of Health, Labour and Welfare – Accredited Facility for Regenerative Medicine Provision PlanSmart Skin Clinic, a specialist in aesthetic dermatology, offers a clear, expert explanation of PRP regenerative therapy for the labia majora.
(*Type II and Type III Regenerative Medicine Provision Plan accreditation number: NA8230001)
Supervisor Information
Chairman, Smart Skin Clinic Group
Kota Ishii
Career:Graduate of Juntendo University School of Medicine / Worked at Tokyo Women's Medical University Hospital and affiliated facilities / Worked at a major aesthetic clinic in Tokyo
Qualifications:Board-certified specialist, Japan Surgical Society / Board-certified specialist, Japanese Society of Anti-Aging Medicine
For those with these concerns
For patients with these concerns, ourPersonalized PRP Injectionis the treatment of choice.
especiallyhave been dissatisfied with how long hyaluronic acid injection results last,feel this way,
and those who find repeated injections a hasslefeel this way.
What Is PRP Regenerative Therapy for the Labia Majora (Personalized PRP Injection)?
PRP (Platelet Rich Plasma)is plasma extracted from your own blood that containsa high concentration of platelets.Platelets are rich inGrowth factorsgrowth factors, which helppromote collagen production and tissue repair..
PRP contains growth factors such as "platelet-derived growth factor (PDGF),""vascular endothelial growth factor (VEGF), and""transforming growth factor (TGF-β)." When injected into the dermal layer of the labia majora, thesepromote collagen production,restoring firmness and elasticity to the tissue.
In recent years, it has attracted attention in the field of regenerative medicineand, in aesthetic medicine,is also used as a skin-rejuvenating treatment. When injected into the labia majora,rather than supplementing the area with an external substance, as with hyaluronic acid,,its greatest feature is that it activates your own cells to rejuvenate the tissue from within..
Three Key Points of Our Personalized PRP Injection
We precisely plan the depth, area, and volume of injection tailored to each patient's individual condition.
Using our proprietary recipe and protocol, we blend growth factors for optimal durability and effectiveness.
Our experienced physicians inject at the optimal angle, depth, and distribution for a natural-looking result.
Comparison with Hyaluronic Acid Injection for the Labia Majora [In-Depth Comparison]
As a volumizing treatment for the labia majora,Hyaluronic acid injectionis a widely performed procedure. However, there are significant differences between hyaluronic acid injection and PRP regenerative therapy.Which one is right for you?Please refer to the comparison table below.
| Comparison point | Personalized PRP Injection (Recommended by our clinic) |
Hyaluronic acid injection |
|---|---|---|
| Treatment details | PRP and growth factors extracted from your own blood are injected topromote tissue regeneration | Injects synthetic hyaluronic acid to add volume |
| Duration | Lasts as long as 4 to 5 years | Absorbed within roughly 6 months to a year *Regular re-injection required |
| Number of Treatments | Typically completed in a single session | Requires re-injection 1–2 times a year to maintain results |
| Results | Natural firmness and plumpness Because the tissue itself regenerates, there is no unnatural feeling |
Overfilling can sometimes result in unnatural bulging |
| Downtime | Almost none(Back to normal activities the next day) | Bruising or swelling may occur (1–2 weeks) |
| Safety | Uses your own blood No risk of foreign-body reaction or allergy |
Carries a risk of foreign body reaction Rare possibility of lumps or calcification |
| Treatment Time | About 20 minutes (plus roughly 1 hour of waiting time) | About 5–30 minutes |
| Total cost over 5 years |
Cost of a single treatment only Approximately ¥160,000–200,000 |
Requires 5–10 re-injections Approximately ¥500,000–1,000,000 or more |
For those considering switching from hyaluronic acid to PRP
Even if you've previously had hyaluronic acid injections, switching to PRP regenerative therapy is possible. Once the hyaluronic acid has been absorbed by the body, you can safely undergo the treatment. If you find the annual re-injections a hassle, or you're looking for a longer-lasting solution, please feel free to consult with us.
Causes of Labia Majora Aging and How PRP Works
Main Causes of Labia Majora Aging
The labia majora undergo various changes due to aging, childbirth, and shifts in hormonal balance.
3 Ways PRP Benefits the Labia Majora
Growth factors contained in PRP activate fibroblasts, promoting the production of collagen and elastin. This improves tissue elasticity, resulting inimproved sagging and wrinkles..
Growth factor (VEGF) promotes angiogenesis and improves blood flow. As cellular metabolism becomes more active,the tissue is restored to ayouthful, healthy state.
The regenerative effects of PRP promote cell repair in the subcutaneous tissue,compensating for volume loss.. Natural plumpness is restored. Rather than supplementing from outside as with hyaluronic acid,your own tissue regenerates,resulting in a more natural-looking outcome.
8 Features of Personalized PRP Injection
Results Last Approximately 4 to 5 Years
Lasts 4–5x longer than hyaluronic acid
Typically Completed in a Single Session
No need for repeated visits
A Non-Surgical Injectable Treatment
No scarring
Natural-looking results with no discomfort
The tissue itself regenerates
Virtually no downtime
Back to daily activities the next day
No risk of foreign-body reaction
Uses your own blood
Personalized treatment
Optimized for each individual
Facility certified by the Ministry of Health, Labour and Welfare
Registered regenerative medicine provider
Treatment Flow
Free Consultation
Please feel free to discuss any concerns or wishes you may have. Our clinic never engages in sales pitches or upselling, so a consultation alone is completely fine.We conduct consultations in afully private room, with privacy carefully protected.
Consultation & Design
We conduct a detailed consultation to determine whether Personalized PRP Injection is suitable for you and how to design the treatment for a natural-looking improvement.We create an individualized designtailored to each patient's condition.
Blood Draw
PRP is a form of regenerative medicine that uses your own blood. You can think of it as similar to a standard blood draw.
PRP Extraction & Processing (waiting time: approx. 1 hour)
PRP is extracted and processed at our in-house processing facility. As this is a delicate process that takes time,please allow about an hour of waiting time(you are free to go out during this time).
Anesthesia
Anesthesia is administered before the treatment, soyou will feel little to no pain during the PRP injection.Because this is such a sensitive area, we place great care in minimizing any discomfort.
PRP Injection (approx. 20 minutes)
Based on the pre-planned design, we precisely inject "the appropriate amount of PRP at the appropriate depth."
End of Treatment — Head Home
You may return home immediately after the treatment. You may experience slight redness or swelling around the injection site, but this will subside within a few days.
Pricing
[Yokohama Clinic Exclusive] Labia Majora PRP Injection
20% OFF Campaign Now Running
*All prices include tax.
*We offer self-pay (non-insured) treatments only; insurance does not apply.
*Price includes consultation and needle fees. There are no additional upsells on the day of treatment.
Monitor Requirements
①Intended Use｜Featured on our website, Instagram, and other media (published with privacy safeguards so individuals cannot be identified)
②Procedure｜Pay the standard price at your first visit → receive a refund of the difference when monitor photos are taken (approximately 3 months after treatment)
Treatment details
FAQ
Q.Which do you recommend for the labia majora — PRP injection or hyaluronic acid filler?
Q.How many treatments are needed?
Q.Is the treatment painful?
Q.How much downtime is there?
Q.When will I start to notice results?
Q.I've had hyaluronic acid injections before — can I switch to PRP?
Q.Can I have the treatment while menstruating?
Q.Will this affect pregnancy or childbirth?
Q.Will anyone else be able to tell?
Q.Are there any side effects or risks?
Please feel free to reach out first
We welcome your questions about PRP injection and offer free consultations — please feel free to book one.
We'll propose the treatment plan best suited to your concerns.
There is never any high-pressure sales, so please consult with us with confidence.
About the physician supervision of this site
This site is operated under the supervision of a Smart Skin Clinic supervising physician.
This page was produced in accordance with the Medical Advertising GuidelinesMedical Advertising Guidelinesrevised and enforced in June 2018, under which we produce and provide this information.
- Scope of supervision: treatment descriptions, risks and side effects, price display
- Last medically reviewed: January 29, 2026
*Treatment effects vary from person to person. Please be sure to consult a physician regarding side effects and risks.
Physician Who Supervised This Page
Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.