Lately, I've grown increasingly concerned about the changes that come with age. I felt I'd reached the limits of self-care when it came to sagging around my mouth, hollow cheeks, nasolabial folds, sunken temples, and the wrinkles and hollows under my eyes. I found Smart Skin Clinic through an online search,and it had extremely high reviews,so I decided to come here. I chose Profhilo because I wanted minimal downtime, safety, and rejuvenation of my whole face. Treatment began right after the consultation, with injections at five points on each side of my face, ten in total. The moment of the needle is just a slight prick, but the discomfort builds as the solution goes in. Still, it's not painful enough to require anesthesia. After the procedure, the injection sites swell a little like mosquito bites, but it's mild enough to hide with a mask and doesn't interfere with heading home. In my case, one spot under my eye bruised, and I'm still covering it with a mask for work. I expect the bruise to fade in about 10 days. On day 1 after the procedure, my cheeks felt fuller. It's now day 5, andthe results far exceed what I imagined,and I couldn't be happier.
Jalpro Super Hydro Japan's Lowest Price Level 1cc 19,900 yen~|Smart Skin Clinic [Official]

For those who want to "address sagging at its root" without surgery
_2172x724_01.jpg)
| Sessions (2.5 cc) | twice | Per 1 cc Price |
|---|---|---|
| Once | 49,800 yen | 23,900 yen |
| 2 sessions | 95,600 yen (47,800 yen per session) | ¥19,120 |
| 3 times | 137,400 yen (¥45,800 per session) | ¥18,320 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
At our clinic, free consultations are handled directly by specialized physicians, not by cosmetic counselors as at large clinics.
For this reason, there is no hard selling at any point during the free consultation, which has made it very popular even with clients who are new to cosmetic care. Please book with confidence.
What is Jalupro Super Hydro?

Ingredients and mechanism of action (skin-nurturing injection and bio-remodeling action)
Jalupro Super Hydro isNon-cross-linked hyaluronic acid, amino acids, and peptidesIt is a "skin-nurturing injection" made up of these three groups of ingredients.
- non-cross-linked hyaluronic acidcombines two types of different molecular weights (high molecular weight: 2000kDa, low molecular weight: 200kDa) to bring water retention and elasticity to the superficial and deep layers, respectively.
- Amino acidsincludes seven types (glycine, proline, lysine, leucine, alanine, valine, and arginine) and is an important component that supports fibroblasts and forms the foundation for collagen production.
- Peptidescontains three types (acetyl decapeptide-3, oligopeptide-24, and acetyl tetrapeptide) that help promote the cell activation involved in skin regeneration and tightening.
By working on the skin's foundation (the dermis), these combined ingredients aim for "structurally beautiful skin" with moisture, firmness, and elasticity. Jalupro Super Hydro isInjection treatment that improves the quality of the skin itselfIt is drawing attention as
Differences from conventional hyaluronic acid injections and thread lifts
Unlike hyaluronic acid injections, which are mainly about "volume replenishment," or thread lifts, which center on "physical traction," the core of Jalupro Super Hydro is "bio-remodeling" that draws on the body's own healing ability. Because tissue reconstruction progresses after injection, the result is very natural and unlikely to leave irregularities. In addition, by evenly hydrating the full thickness of the skin, it can improve skin quality at the same time, so even as a standalone treatment it can offer multifaceted anti-aging care.
Who is it recommended for? (Suitable concerns and areas)
- Concerned about sagging along the jawline
- A thread lift helped temporarily, but the sagging has come back...
- Bothered by hollow cheeks, but worried that hyaluronic acid might leave them looking overfilled...
- Worried that a thread lift might cause dimpling or tightness...
- I want to lift and firm my face
How long do the effects last? (Duration)
With Jalupro Super Hydro, in addition to the sense of moisture felt right after injection, an increase in elasticity from fibroblast activation typically progresses from about two to three weeks later and generally lasts three to six months. The more treatments you receive, the more collagen density increases and the longer the effects tend to remain stable. Recommending maintenance injections every six months makes it easier to sustain a sense of lift and improved skin quality over the long term. Results vary from person to person, but the duration can be extended further depending on post-treatment lifestyle and skincare.

Causes of Sagging
As we age, the following changes occur in the skin and the tissues beneath it.
- Outer skin: stretches
- Inner collagen and elastin: decrease
- Inner fat tissue: atrophies
- Inner bone: recedes
- Ligaments (supporting ligaments) that connect the outer and inner layers: stretch and loosen
These factors do not act in isolation; they interact with one another to produce sagging.

Our "Signature" Jalupro Super Hydro
We use genuine "Jalupro SuperHydro®."
CurrentlyAdopted in more than 70 countriesIt is a preparation with a proven track record. Across the Jalupro series as a whole, over 1.5 million treatments have been performed worldwide,A preparation whose safety and efficacy are recognized worldwide.
Jalupro Super Hydro is an innovative treatment that strengthens the ligaments (supporting ligaments) without using any device, achieving a natural lift and improved skin quality at the same time.
Some patients at Smart Skin Clinic tell us, "Because the prices are so low, I worry whether the product is genuine."
To ease such concerns,we open a brand-new formulation on the spot and show it to you,which gives our patients peace of mind.

Comparing our clinic with others
Comparison Chart with Other Hospitals (Jalpro Super Hydro)
Why choose our clinic?
Please review the differences in pricing, structure, and transparency.
-
Price (Face 2.5cc)
General Market Trends and PricesOnce ¥60,000–¥110,000※Based primarily on standard listing price ranges at major clinics in Tokyo (excluding campaigns)
2 sessions ¥167,200 to ¥217,800
3 times ¥250,800 to ¥280,000Smart Skin Clinic (Tax Included / Total Amount)Once 59,800 yen
2 sessions 109,600 yen
3 times 149,400 yenAll-inclusive price shownConsultation and acupuncture includedNo upsells on the dayCompared to other hospitals, the maximumSave ¥130,600! -
Display and Additional Fees
General trendConsultation fee, needle cost, anesthesia, medication cost, etc.separatelymay occurSmart Skin ClinicTotal cost (including consultation and acupuncture)
No upsells on the day -
Counseling System
General trendBeauty Counselor-Centered InformationSmart Skin ClinicPhysician direct response
No hard selling -
Transparency of Formulations
General trendExplanation of the delivery confirmationif notもSmart Skin ClinicOpen a new product on the spot and present it to you. -
Jalpro SH Case Results
General trendby the institutionNon-public · VariabilityYesSmart Skin ClinicOver 2,000 casesOur hospital's tally (total number of Jalpro SH cases) -
Same-day treatment
General trendIn some cases, we may need to reschedule for another day.Smart Skin ClinicSame-day appointments available※※Availability and eligibility apply.
Comparisons serve as a general guideline for our hospital's policy. Results may vary depending on the hospital and timing.
Why is our clinic so affordable?
Kota Ishii
Chairman, Smart Skin Clinic
Patient Testimonials
Consistently highly rated in patient reviews
Google Reviews 4.5/5.0

Hot Pepper Beauty 4.57/5.00

KireiPass rating4.30/5.00

Kumapon rating4.71/5.00

Gangnam Unni rating9.3/10.0

Smart Skin Clinic's Jalupro Super Hydro — Pricing Among the Lowest in Japan
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| Sessions (2.5 cc) | twice | Per 1 cc Price |
|---|---|---|
| Once | 49,800 yen | 23,900 yen |
| 2 sessions | 95,600 yen (47,800 yen per session) | ¥19,120 |
| 3 times | 137,400 yen (¥45,800 per session) | ¥18,320 |
*We offer self-pay (non-insured) treatments only; insurance does not apply.
Prices are shown all-inclusive, covering consultation and needle fees.
There is no separate upselling on the day.
FAQ
- What is the difference between Jalupro and Super Hydro?
-
Jalupro comes in several types: Classic is suited to areas such as around the eyes, while Jalupro Super Hydro combines hyaluronic acid and amino acids with peptides and is especially designed to target skin tightening by injecting into the ligaments.
- When do the effects of Jalupro Super Hydro begin to appear?
-
Many people find it easy to feel added moisture right after the injection and notice a change in firmness and tightness within about one to two weeks. Jalupro Super Hydro is characterized by working gradually on the skin's structure.
- What are the drawbacks of Jalupro Super Hydro?
-
Bruising and swelling may occur in rare cases, but because it uses non-cross-linked hyaluronic acid, lumps are unlikely and downtime is relatively short. Jalupro Super Hydro has a formulation designed with safety in mind.
- Is Jalupro effective under the eyes?
-
Dedicated formulations such as Jalupro Classic and Jalupro Eye are commonly used under the eyes. Jalupro Super Hydro is more often used to tighten the skin of the cheeks, jawline, and neck.
- Is the treatment painful? I am not good with pain, so will I be all right?
-
Many people find the Jalupro Super Hydro treatment to be less painful than they expected.
- How much downtime is there? Can I return to my normal routine right after the treatment?
-
Temporary redness or swelling may occur after the Jalupro Super Hydro treatment, but in most cases it settles within one to two days. Downtime is relatively short, and makeup can be applied from the next day.
- How many sessions do I need? What is the recommended frequency and interval?
-
Typically, three treatments performed at one-month intervals form the basic course. After that, maintenance every six months is recommended. With Jalupro Super Hydro, repeated sessions can help stabilize the skin structure.
- How is Jalupro Super Hydro different from Profhilo?
-
The effects are similar, but strictly speaking, the areas they target are different. The main target of Jalupro Super Hydro is the ligaments (supporting ligaments). The main targets of Profhilo are collagen and elastin production in the dermis and the activation of fat cells in the subcutaneous tissue.
- Can anyone receive this treatment? Are there age limits or cases where it cannot be performed (such as pre-existing conditions or pregnancy)?
-
Generally, it is intended for healthy individuals aged 18 and over.Jalupro Super HydroIt is not recommended for those who are pregnant or breastfeeding, or who have severe skin conditions or serious illness. A physician will confirm suitability before the treatment.
Treatment areas for Jalupro Super Hydro
Jalupro Super Hydro is a treatment that primarily targets the ligaments of the face. For this reason, recommended points are chosen so that the active ingredients reach the facial ligaments efficiently.
Approximately 0.1 to 0.2 ml is used per site across 13 points each on the face and neck, for a total of about 2.5 ml of Jalupro Super Hydro.
The following two diagrams (first: face, second: neck) show the representative areas where Jalupro Super Hydro is injected. By injecting particularly around the ligaments where sagging is a concern, the aim is to achieve natural tightening.


Jalupro Super Hydro'sRecommended Number & Frequency of Treatments
About three sessions at one-month intervals are recommended. After that, maintenance about once every six months to a year is recommended.
The Jalupro Super Hydro treatment process
You can easily book from your smartphone.
It is a "smart," simple reception process without complicated procedures.
The Jalupro Super Hydro treatment begins with counseling by a physician. We never push you to have the treatment, so you are welcome to visit even if you only want a consultation.
For Jalupro Super Hydro injections, a physician who understands the skin's structure and the position of the ligaments carefully injects the product into a shallow or slightly deeper layer according to the goal. To bring out a natural sense of lift and firmness, the injection volume and points may be designed individually. The injection typically takes about 15 to 30 minutes in total. We aim to create an environment where you can relax while we value conversation with you throughout.
After treatment, we explain any necessary precautions. Jalupro Super Hydro is a same-day treatment that lets you go home the same day, and face washing and makeup are usually possible from the next day. As a basic rule, vigorous massage, long baths, and excessive alcohol should be avoided for several days, but no special care is required.
For Your Daily Care
To every day beyond,
Skin-nurturing care.
&DR.is a skincare brand born from the findings of cosmetic dermatology. Its first product, BAKU, is a skin-nurturing serum that focuses on gentleness, centered on the plant-derived skin-conditioning ingredient BAKUCHIOL. It can be used gently every day, both in the morning and at night.
Risks and side effects of Jalupro Super Hydro
What side effects can occur after injection? (swelling, bruising, redness)
Jalupro Super Hydro is a minimally invasive injectable treatment, but mild side effects may occur right after the procedure. Common ones include swelling, redness, bruising, and a feeling of tightness at the injection site. These are natural biological reactions and most settle within a few days.
Bruising in particular is more likely in areas where the skin is thin, and many people return to daily life while covering it with makeup. Any pain during the procedure is also very mild and can be reduced further with anesthetic cream.
Rare risks and cases requiring caution
The non-cross-linked hyaluronic acid, amino acids, and peptides used in Jalupro Super Hydro have been confirmed to be highly safe, but in rare cases allergic reactions or skin discomfort may occur. Those who have experienced skin problems with cosmetic injections in the past, or who have hypersensitivity to medications, should always consult a physician in advance.
In addition, as with any injection, there is a very rare risk of infection or inflammation. To minimize these risks, it is important to receive treatment at a reliable medical institution and to avoid firmly touching or rubbing the area after treatment.
What you can do to minimize side effects
After the Jalupro Super Hydro treatment, you can minimize the risk of side effects by being mindful of a few things. On the day of treatment, avoid strenuous exercise, alcohol, and long baths, and refrain from excessively boosting your metabolism and blood flow.
It is also ideal to avoid actions that place strong pressure on the injection site (massage, sleeping face-down, etc.) for two to three days. If you are pregnant, breastfeeding, or have skin problems, consult your physician in advance about whether the treatment is suitable, and prepare so you can receive it with peace of mind.
Those who are not eligible for the treatment
Jalupro Super Hydro is an injectable treatment confirmed to be highly safe; however, Treatment cannot be provided if any of the following apply.
- Those who are pregnant or breastfeedingThose who are
- At the treatment siteInfection, severe inflammation, or herpesThose with skin conditions such as
- Severe autoimmune diseaseandBleeding disordersThose whose general condition is unstable, such as serious heart or kidney disease
- Anticoagulants or antiplatelet agentsThose taking medications that increase bleeding risk, such as the above, without approval from their treating physician
- In the pastAllergic reaction to hyaluronic acid preparations or peptide-based injectionsThose who have experienced
Also,Impaired barrier function immediately after intense sunburn or due to severe atopic dermatitisIf any of these are present, the timing of the treatment may be postponed. To ensure safe treatment, please always inform your physician of any pre-existing conditions, current medications, and life events (such as trying to conceive) at the time of counseling. If you have any questions, discussing them in advance allows us to propose a more suitable treatment plan.
Summary
Jalupro Super Hydro is a "structural anti-aging" injection that supports the ligaments while enhancing skin quality. With its short downtime, it can be applied not only to the face but also to the neck and the backs of the hands, making it well suited to natural rejuvenation.
At Smart Skin Clinic, drawing on our experience of more than 10,000 injectable procedures per year, physicians examine and perform the treatments directly, without counselors. We do no sales or upselling whatsoever, and by eliminating unnecessary costs we keep prices accessible. We have created an environment where you can consult with peace of mind. Please feel free to come in for a consultation first.
(Note)Details
| Treatment Time | About 15 minutes (not including counseling) |
| Recommended Number & Frequency of Treatments | - About three times at one-month intervals - After three sessions, maintenance in six months to one year is recommended |
| Downtime | About 24 hours |
| Treatment on the day of counseling | Available |
| Makeup | From the next day |
| Skincare | From the next day |
| Shower | Possible from the same day |
| Pain | A slight pricking sensation when the needle is inserted. |
- This limited-time special price may end without notice. Now is your chance to receive it at the lowest price level in Japan.
- Performed by an Anti-Aging Society board-certified specialist with over 10,000 skin-nurturing injection procedures
- A free consultation with a physician (normally valued at 10,000 yen)
- Minimal downtime, with natural improvements and changes that others won't notice
- Trusted with a 90%-plus satisfaction rating across various reviews and ratings
At our clinic, consultations are conducted directly by a physician, not a beauty counselor. There is no hard selling whatsoever, so please feel free to consult with us.
- The following section offers a detailed explanation for those who wish to learn more about Jalupro Super Hydro.
The history of Jalupro (development background and safety)
Background to the development of the Jalupro formulation
"Jalupro," the base of Jalupro Super Hydro, was created as an anti-aging formulation from Italy. In the early 2000s, physicians who focused on the combination of "non-cross-linked hyaluronic acid + amino acids" for the purpose of skin restructuring developed it as an injection to restore youthfulness from within the skin. It was later adopted in many countries across Europe, Asia, and beyond, and the Jalupro series has grown into a formulation that can address skin concerns across a wide range of ages.
For details on the other Jalupro products in the series, please also see the following articles.
The emergence and evolution of Super Hydro
Jalupro Super Hydro was developed as the latest evolution in the series. It contains a higher ratio of non-cross-linked hyaluronic acid and amino acids than earlier products, and three types of peptides have been newly added. These ingredients support the production of collagen and elastin, which are involved in skin elasticity, and in addition to improved skin quality and moisturizing effects, a growing number of people report a sense of "skin tightening" and "reduced jawline slackness." Some physicians have also reported using injections into the ligament (supporting ligament) areas for structural support, making it a suitable option for those concerned about mild sagging.
European approval and safety track record
Jalupro Super Hydro has obtained the "CE mark," the safety standard required in the European Union, and has an extensive track record of use in clinical settings. The Jalupro range as a whole has been used in a cumulative total of more than 1.5 million procedures across over 70 countries worldwide, making it a product that has built trust over the long term. The injections use non-cross-linked hyaluronic acid, which is unlikely to cause lumps or excessive bulging, another reason it is easy to receive with peace of mind.
The fourpoints
①Natural lifting effect (tightening through ligament reinforcement)
Jalupro Super Hydro is a formulation designed to give three-dimensional firmness to loosened tissue and tighten the jawline by injecting around the "ligaments (supporting ligaments)" that support the facial structure. Unlike surgical lifting, it is characterized by an approach that "reshapes from the foundation" while preserving natural expressions. It is an option that aims for a natural-looking result among injectable treatments, geared toward those who have begun to notice cheek sagging or slackness.



②Skin-quality improvement (enhanced moisture, firmness, and radiance)
Jalupro Super Hydro contains a well-balanced combination of non-cross-linked hyaluronic acid plus seven amino acids and three peptides involved in skin structure. By working on the dermal layer, they help balance the skin's moisture, elasticity, and radiance from within. With a composition that addresses "signs of aging in overall skin quality" such as dryness, uneven texture, and fine lines, many people notice changes such as smoother, more even-looking skin after treatment.
③Short downtime (makeup possible from the day after treatment)
One reason so many people choose Jalupro Super Hydro is that it involves relatively little downtime after treatment. Because it is an injectable treatment, very mild redness or swelling may occur, but this generally becomes unnoticeable within one to two days. In most cases makeup can be applied the next day, making it an easy treatment to incorporate for busy people or those who want to fit it around their work schedule. It is also a reassuring choice for those considering their first injectable treatment.
④Safety demonstrated in countries around the world (extensive case experience)
Jalupro Super Hydro is an injectable formulation adopted by medical institutions around the world, especially in Europe. It has obtained the CE mark (the EU medical device safety standard) and has an extensive track record of use in clinical settings. Since the 2020s, awareness has also grown in Japan, making it one of the treatments now attracting attention. By using non-cross-linked hyaluronic acid, it is unlikely to cause excessive bulging or lumps, with careful attention paid to safety.
Introducing other injectable treatments at Smart Skin Clinic for those with skin-quality concerns
In addition to Jalupro Super Hydro injections, Smart Skin Clinic offers other injection treatments effective for improving skin quality.




If you're interested, please explore the wide range of treatments we offer via the links below.
Legal Notices
Jalupro Super Hydro treatment includes procedures using drugs or medical devices not approved in Japan. The drugs and devices used in treatment are imported personally at the discretion of our clinic's physicians.
Please refer to this page for information on medications and similar items that require caution in personal importation.
Ministry of Health, Labour and Welfare, "Medications and Similar Items That Require Caution in Personal Importation."
Physician Who Supervised This Page

Smart Skin Clinic, Chief Medical Director / Physician
Kota Ishii
We oversee treatment policies across the entire group, tailored to the skin condition of each individual patient. The content on this page has been reviewed and approved in line with our clinic's treatment policies.
Interview with Director Kota Ishii
Kota Ishii, our Chief Medical Director, shares our clinic's approach to patient care.
Group Chief Director, Smart Skin Clinic Group
Ishii Kota
Career
Graduated from Juntendo University School of Medicine
Worked at Tokyo Women's Medical University Hospital and affiliated facilities
Worked at a major aesthetic clinic in Tokyo
Affiliations / Qualifications
Board-certified specialist, Japan Surgical Society
Board-certified specialist, Japanese Society of Anti-Aging Medicine
Smart Skin Clinic
Smart Skin Clinic
A clinic built on the concept of "making aesthetic medicine more accessible and smart."
Rather than spending on ornate interiors, we keep fit-out costs down, and rather than adding equipment indiscriminately, we carefully select only the devices we need to keep equipment costs down.
We aim to "make aesthetic medicine more accessible" for you.
Clinic List
Jimbocho Clinic
〒101-0054
3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo, EX Kanda Nishiki-cho Building 8F (general reception) / 7F
Hours: Mon–Fri 11:00–20:00 / Sat & Sun 10:00–19:00
Yokohama Clinic
〒221-0835
TS Plaza Building 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Hours: 10:00–19:00
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of Smart Skin Clinic's supervising physicians.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
This page is operated as a medical institution's website in accordance with the Medical Advertising Guidelines revised and enforced in June 2018, and is produced under the supervision of our supervising physician.
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