A doctor explains why Jubeluk is "ineffective".

"Does Jubeluk not work?"
Can Jubeluk feel the effects of one session?"
How long do the effects of Jubeluk last?"

Do you have these questions about Jubeluk?

Hello. I am a doctor at Smart Skin Clinic.

JUVELUX is an injectable that can be used for a variety of skin care effects, but it is sometimes said to be "ineffective".
In this issue, a physician explains the effectiveness of JUVELEC and why it is said to be "ineffective.


What are the effects of Jubeluk in the first place?

JUVELUX is a formulation combining "non-cross-linked hyaluronic acid" and "polylactic acid (PDLLA).
Non-cross-linked hyaluronic acid has a structure close to that of natural hyaluronic acid and is effective in retaining moisture. Together with polylactic acid (PDLLA), it activates fibroblasts that produce collagen, leading to beautiful skin.

A type of injectable drug called a skin booster, as the words "skin (skin)" and "boost (boost) the effect" suggest, can be expected to enhance the function of the skin by injecting active ingredients.

Specific benefits you can expect from Jubeluk

As suggested by the name JUVE (youth, vitality, and vigor) LOOK (appearance and expression), JUVELUX can be expected to be effective for a variety of conditions, including the following

  • Fine lines, lack of volume
  • Pore opening
  • Skin elasticity, skin firmness, and skin texture
  • Crater (acne scar), scar indentation

In fact, in the following paper, "In 16 Korean men and women aged 20-65 years, two to three injections of a combination of PDLLA and non-cross-linked hyaluronic acid (≈Juvelock) every 4 weeks resulted in improvement of aging signs and histological examination showed an increase in collagen and elastin fibers in the dermis" The results of the study showed an improvement in signs of aging and an increase in collagen and elastin fibers in the dermis on histological examination.

Overall, statistically significant differences were observed in all signs of aging skin, such as fine wrinkles, skin texture, irregular pigmentation, telangiectasia, and facial erythema before and after treatments. Half (50%) of patients responded that there was more than 50% overall improvement. Histologic examination demonstrated increases in collagen and elastic fibers in the dermis.

Japanese translation: Overall, there was a statistically significant difference in all signs of aging before and after treatment, including fine lines and wrinkles, skin texture, blemishes, telangiectasias, and erythema. Half (50%) of patients reported an overall improvement of 50% or more. No serious adverse events were observed. Histological examination showed an increase in collagen and elastin fibers in the dermis.

Suk Bae Seo, Hyunwoo Park, Ju Young Jo, Hwa Jung Ryu. Skin rejuvenation effect of the combined PDLLA and non cross-linked hyaluronic acid: A preliminary Journal of cosmetic dermatology. 2023 Nov 15; doi: 10.1111/jocd.16085

Why Jubeluk is "ineffective"?

Although Jubelq has been shown to have certain effects, unfortunately, it is sometimes said to be "ineffective". The reasons for this are explained below.

Effects are not immediately apparent.

JUVELUX is not something that you will feel the effects of immediately afterwards. In most cases, the effect will be felt approximately 2 to 3 weeks after the surgery.

In addition, although effects can be achieved with a single treatment, it is usually only after a set of three treatments that significant changes are likely to be felt.

After the procedure, the drug is slowly absorbed into the body over a period of one to two years. In the process, fibroblasts are stimulated and the effect is sustained. Fibroblasts are cells that produce collagen and elastin, which are the source of firmness and elasticity.

Effects are not permanent.

The effects of JUVELUX are not permanent.

Although the process of absorption produces firmness and elasticity, it is broken down into water and carbon dioxide in about 1-2 years and loses its effectiveness.

However, compared to conventional hyaluronic acid preparations, which are gradually absorbed and reduced over time, it can be said that "the effect lasts for a relatively long time.

It's not an adaptation.

Any treatment, not just Jubeluk, is only effective if it is indicated.

JUVELUX works on fibroblasts to promote collagen production, which can be effective for fine lines and wrinkles, pores, acne scars such as craters, and loss of skin elasticity.

On the other hand, it is not expected to have an immediate effect, or to physically increase volume and shape the nose and chin, or to have an effect on the muscles.

Lack of physician skill

The result of JUVELUX depends on the skill of the physician. Insufficient knowledge or skill may make it difficult to achieve the desired effect.

The treatment methods of JUVELUX are (1) aqueous light injection, (2) Potenza, (3) dermapen, and (4) manual injection. The ➀②③ is basically performed on the entire face. The advantage of using a machine is that the drug can be injected to a uniform depth. (4) can be performed on either the whole face or locally.

In both treatment methods, technique is important.

Inappropriate postoperative spending.

If you expect JUVELUX to have a beautiful skin effect, it may not only be ineffective but may even have the opposite effect if the postoperative period is spent improperly.

For example, you cannot take a bath on the day of surgery. You can take a bath the next day, but avoid exercise and other activities that heat up the body for about a week.

The affected area after surgery is in a delicate state and is more prone to dryness and UV damage. Moisturizing and UV protection should be taken even more thoroughly than usual.

JUVELUX Side Effects

Although JUVELUX is an effective formulation, side effects may occur due to physical constitution and other factors.

JUVELUX is a preparation approved by the U.S. FDA, Japan's Ministry of Health, Labor and Welfare, and Korea's KFDA, and is said to be relatively safe, but it has not been approved by the MHLW. It is not approved by the Ministry of Health, Labour and Welfare of Japan. It cannot be used if the patient is allergic to hyaluronic acid or anesthesia. There is also a rare risk of infection.

If symptoms such as pain or increased swelling appear after surgery, please consult the clinic immediately.

What you can do to avoid the "ineffective" result of receiving Jubeluk.

Here are some measures you can take on your own to avoid the "ineffective" results of receiving JUVELUX.

Receive an effective number of treatments with JUVELUX

As an effective way to receive JUVELUX treatments, it is recommended to first receive "a set of three treatments at one-month intervals", followed by "maintenance every six months to a year". The repeated treatment will help to sustain collagen production, and the effect is more likely to last for a long period of time.

Since continuous treatment is necessary to maintain the effects of the treatment, another point to be checked is whether the cost can be continued.

Choose a medical institution you can trust.

When receiving JUVELUX, choose a reliable medical institution from among several clinics.

Check the clinic's website, SNS, word-of-mouth, etc., and compare treatment methods and case results. Also check the cost considering ongoing treatment.

Once you have narrowed down the potential clinics, you will receive advice on the effective frequency of use of JUVELUX and how to spend your time after the surgery at the preliminary consultation, and ask any questions that are unclear. Please resolve any doubts you may have and accept the treatment only after you are satisfied with the results.

Jubeluk to Smart Skin Clinic

Have your questions and concerns about the effectiveness of Jubeluk been answered?

JUVELUX is expected to have a lasting effect due to its time-intensive, skin-nurturing approach to working. Understanding the characteristics of JUVELUX and following the postoperative lifestyle precautions will help avoid the "JUVELUX does not work" result.

At Smart Skin Clinic, our technically skilled physicians perform the procedure by hand. We will also advise you on appropriate treatment intervals and post-operative lifestyle. Our fees are easy to maintain so that you can feel the effects of the treatment.

Free counseling is available. If you have any questions about Jubeluk, please feel free to contact us.

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Suk Bae Seo, Hyunwoo Park, Ju Young Jo, Hwa Jung Ryu. Skin rejuvenation effect of the combined PDLLA and non cross-linked hyaluronic acid: A preliminary Journal of cosmetic dermatology. 2023 Nov 15; doi: 10.1111/jocd.16085

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