exosome nasal spray therapy
Limited Time Campaign
Exosome nasal drops [umbilical cord derived] "20%" off the initial price
(Initial price) 29,440 yen → 23,522 yen
Period｜June 12, 2024 - June 30, 2024
Red text indicates the price after discount is applied.
I know what an exosome infusion is, but what is a nasal drip?" What's the difference?"
I'd like to get exosome nasal drip, but I'm not sure where to go."
Do you have any of these questions or concerns?
Exosome is a well-known anti-aging treatment, and there are various ways to administer it, including intravenous infusion and injection into the face. Smart Skin Clinic, a cosmetic dermatology clinic, will provide a professional and easy-to-understand explanation of the "nasal drip" method of administering Exosome through the nose.
*If you are comparing clinics and are concerned about fees, you may save time by jumping to the table of contents below.
What is Exosome Nasal Drops?
The procedure involves "nasal administration" of exosomes, which have anti-aging properties.
IV infusion and dermapen are perhaps the more well-known methods of administering exosomes.
Intranasal administration can deliver exosomes to the brain, preventing dementia, improving concentration, and improving brain fatigue.
What is an exosome?
Exosomes are substances originally found in the body. In medical terms, they are small cellular vesicles encased in a lipid bilayer membrane that are actively secreted by various cells and play an important role in intercellular communication.
Through this role of intercellular communication, exosomes exert diverse effects, including anti-apoptotic, anti-inflammatory, neurogenic, and angiogenic effects. As a result of exerting these effects, they provide so-called anti-aging effects.
Variations of exosome injection methods
Exosome injection methods can be broadly divided into two patterns: systemic and local administration.
systemic administration
- intravenous drip
- injection
- nasal drip
For more information on intravenous administration, click here.
local administration
- Vital Injector
- dermapen
For more information on dermapen dosing, click here.
Effect
- Dementia Prevention
- Improvement of brain fatigue
- Improvement of insomnia
- Improved concentration
- allergic rhinitis
- Improvement of post-corona sequelae
*Expected effects
*There are individual differences.
To deliver certain substances to the brain, they must pass through a barrier called the BBB.
BBB is a medical term and stands for Blood Brain Barrier, which in Japanese is the cerebrovascular barrier.
To overcome this hurdle barrier, nasal administration has gained attention as a non-invasive (damage-free) and effective route to get drugs to the central nervous system (brain).
Numerous studies have confirmed that intranasal (intranasal) administration can bypass the BBB and deliver low molecular weight substances and high molecular weight proteins to the central nervous system (brain).
Nasal administration has the advantages of noninvasiveness and high utility. Intranasal administration facilitates the delivery of all types of drug molecules and stem cells to bypass the BBB and reach the CNS, providing a non-invasive and effective method for stem cell therapy in CNS diseases.
Yu-Ting Zhang, et al. Advances in intranasal application of stem cells in the treatment of central nervous system diseases. volume 12, Article number: 210 (2021) .
Effectiveness of Nasal Nasal Therapy in Patients with Alzheimer's Disease
Data are available on nasal drip therapy for patients with Alzheimer's disease.
By using exosomes, remarkable improvement was seen in refractory diseases such as Alzheimer's disease, cerebral infarction, atopic dermatitis, rheumatoid arthritis, and pollinosis.
Without the need for expensive "transplant" surgery,It can be treated only by intravenous infusion, application as a topical drug, or inhalation through the nose.
This innovative technology is the subject of a large-scale clinical collaboration with the University of Bergen, Norway, beginning in 2019.
Minoru Ueda, "Threatening Regenerative Medicine: What is Cultured Supernatant?
Advantages/Disadvantages of nasal drops
Advantages
Administering through the nose allows the exosomes to reach the brain.
The blood vessels that go to the brain have a barrier called the BBB (blood-brain barrier) that allows only certain components to go to the brain. Therefore, in the case of intravenous administration, it is not possible to efficiently deliver the ingredients to the brain.
On the other hand, as mentioned earlier, nasal administration of exosomes (intranasal administration) allows them to reach the brain directly while bypassing the blood-brain barrier.
Demerit
One disadvantage would be that it would be costly.
Risks and Side Effects
It is basically the same as an exosome infusion. Unlike an intravenous drip, no needles are inserted, so there are no side effects from needle insertion.
How to use nasal drops (Instructions for use)
Features of Smart Skin Clinic's Exosome Nasal Drop Therapy
Use of umbilical cord-derived exosomes
SmartSkin Clinic uses exosomes derived from the umbilical cord, which are one of the three major types of exosomes: (1) umbilical cord-derived, (2) fat-derived, and (3) pulp/marrow-derived.
When compared to other exosomes, umbilical cord-derived exosomes contain 14 times more effective components, as shown in the figure below.
We will also introduce two of these "active ingredients," including specific data.
(1) Rich in active ingredients for skin
The first is data on active ingredients for "skin.
Exosomes have various anti-aging effects, one of which is their effect on "skin. As shown in the figure below, umbilical cord-derived exosomes contain more active ingredients for skin and skin than other exosomes.
(2) Rich in rejuvenating protein "GDF-11
The second will be data on ingredients involved in "rejuvenation.
There is a component called GDF-11, which is involved in rejuvenation, and is abundant in umbilical cord-derived exosomes, as shown by the following data.
Commitment to price and quality
We are committed to price and quality. In order to realize this commitment, we are implementing various initiatives. We are implementing various cost-cutting measures (e.g., less glamorous interior design, elimination of receptionists to reduce labor costs, etc.).
For more information, please click here.
Charge
Limited Time Campaign
Exosome nasal drops [umbilical cord derived] "20%" off the initial price
(Initial price) 29,440 yen → 23,522 yen
Period｜June 12, 2024 - June 30, 2024
Red text indicates the price after discount is applied.
| 5cc per bottle [for one week]. | |
|---|---|
| Initial Price | 29,440 yen → → → $3,000 23,522 yen [Normal to 20%OFF |
| one (object) | |
| Set of 2 bottles (for 2 weeks) | (35,800 yen per bottle) |
| Set of 4 bottles (1 month's supply) | (32,800 yen per bottle) |
| Set of 12 (3-month supply) | (28,800 yen per bottle) |
*Our clinic is not insured, but free medical care
All prices include tax.
Smart Skin Clinic
Smart Skin Clinic
The concept of the clinic is to "make cosmetic medicine more accessible and smart. is the concept of the clinic.
Instead of eliminating ornate interiors to reduce interior design costs and installing equipment in the dark, we carefully select the equipment we need and reduce the cost of the equipment.
We aim to "make cosmetic medicine more accessible" for you.
Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)
Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)
About the physician supervision of this site
About the physician supervision of this site
This site is operated under the supervision of the Smart Skin Clinic supervising physicians.
This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.
This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.