PRP
Using your own blood,
naturalanti-aging care.
What we aim for is not flashy change.
Something that will let you keep liking yourself a year from now, and five years from now—
we provide "natural, seamless anti-aging care."
Duration
5years and more
Downtime
Almost none
Number of Treatments
1Completed in one session
*Standard

Using your own blood,
naturalanti-aging care.
What we aim for is
not dramatic change.
Something that will let you keep liking yourself a year from now, and five years from now—
we provide "natural, seamless anti-aging care."
Duration
5years and more
Downtime
Almost none
Number of Treatments
1Completed in one session
*Standard

The signs that appear with age are
not just a matter ofthe "surface"of the skin.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs involve not only the surface of the skin but also, deep beneath it,"tissue volume loss."is involved.
Rather than unnaturally packing something into the lost foundation, it encourages tissue to regenerate from within using the power of your own cells.
That is Smart Skin Clinic's approach.
The signs that appear with age are
not just a matter ofthe "surface"just
It is not a problem of.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs involve not only the surface of the skin but also, deep beneath it,"tissue volume loss."is involved.
Rather than unnaturally packing something into the lost foundation, it encourages tissue to regenerate from within using the power of your own cells.
That is Smart Skin Clinic's approach.
What Is Personalized PRP Injection?
Personalized PRP injection is a regenerative medicine treatment in which platelets are purified to a high concentration from your own blood and injected into the area of concern.
The growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than "physically filling in wrinkles" as hyaluronic acid does,your own cells regenerate the tissue,so the result looks extremely natural.
STEP 01
Blood Draw

A small amount of blood is drawn
STEP 02
Purification

PRP is purified to a high concentration, and
FGF is added as needed
STEP 03
Injection

To the optimal layer
The appropriate amount is injected with precision
At Smart Skin Clinic, a growth factor (FGF) may be added depending on the patient's condition.
Based on past clinical data, we carefully design the injection volume, depth, and placement to minimize risks such as excessive swelling or lumps.
Personalized PRP Injection
Personalized PRP injection is a regenerative medicine treatment in which platelets are purified to a high concentration from your own blood and injected into the area of concern.
The growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than "physically filling in wrinkles" as hyaluronic acid does,your own cells regenerate the tissue,so the result looks extremely natural.

STEP 01
Blood Draw
A small amount of blood is drawn

STEP 02
Purification
PRP is purified to a high concentration, and
FGF is added as needed

STEP 03
Injection
To the optimal layer
The appropriate amount is injected with precision
At Smart Skin Clinic, a growth factor (FGF) may be added depending on the patient's condition.
Based on past clinical data, we carefully design the injection volume, depth, and placement to minimize risks such as excessive swelling or lumps.
Our Philosophy
Naturally, beautifully.
Smart Skin Clinic as a "hub for anti-aging care"
As a "hub for anti-aging care"
Smart Skin Clinic
We continue to pursue "a more natural and beautiful rejuvenation,"
and we hope to be your "hub for anti-aging care."
That is precisely why, even with PRP treatments, we do not seek unnatural change.
What we aim for is that, a year from now and five years from now,
"you can still love your own face"—a natural beauty with no sense of unease.."
We continue to pursue "a more natural and beautiful rejuvenation," and we hope to be your "hub for anti-aging care."
That is precisely why, even with PRP treatments, we do not seek unnatural change.
What we aim for is to help you keep loving your face—a year from now and five years from now—"a natural beauty with no sense of unease.."



As a hub for anti-aging care, we offer Profhilo, various devices, exosomes, and more,
and precisely because we have such a wide range of options, we do not make PRP-first recommendations from the outset.
First, we listen carefully to your concerns and recommend only "the treatment that is truly right for you."
What you need, in the amount you need—that isthe philosophy of Smart Skin Clinic..
As a hub for anti-aging care, precisely because we have a wide range of options—including Profhilo, various devices, and exosomes—we do not recommend PRP from the outset.
First, we listen carefully to your concerns and recommend only "the treatment that is truly right for you."
What you need, in the amount you need—that isthe philosophy of Smart Skin Clinic..
Our Protocol
Finding the Best Solution Just for You
Four Points of Personalization
The key in PRP therapy is not to rely too heavily on a physician's personal intuition.
At our clinic, to deliver consistent, natural results, we have established clinical evidence and standards for every step of the process.
The key in PRP therapy is not to rely too heavily on a physician's personal intuition. At our clinic, to deliver consistent, natural results, we have established clinical evidence and standards for every step of the process.

- Personalized Diagnosis
Based on our clinic's case data, we analyze your bone structure and skin condition. We determine whether PRP is the best option by comparing it against other alternatives.
- Personalized Purification
Our clinic's own purification protocol, derived by synthesizing a wealth of clinical results.


- Personalized Design
We calculate the structure of your face to determine "where and in what amount to place the material for the most natural lift of the tissue." The physician builds a blueprint before proceeding with the treatment.
- Personalized Injection
Our group has performed over 24,000 injection procedures annually. We deliver the right amount to the right layer with precision.

Case StudiesSmart Skin's PRP, as the results prove
Case Studiesas proven by
Smart Skin's PRP
Our clinic has accumulated a wealth of case studies and treatment results in PRP therapy alone.
Based on this wealth of data, tailored to each individual's bone structure and skin condition,
we provide "personalized treatment" through diagnosis, purification, design, and injection.
Our clinic has accumulated a wealth of case studies and treatment results in PRP therapy alone.
Based on this extensive data, we provide "personalized treatment"—diagnosis, purification, design, and injection—tailored to each individual's bone structure and skin condition.
Number of PRP Treatment Cases
1,000and more
*Jimbocho Clinic (period: June 2023 – March 14, 2026)
Yokohama Clinic (period: July 2025 – March 14, 2026)
dark circles under the eyes
Three months later

Nasolabial folds
Three months later

The entire face
Three months later

The entire face
Three months later

*The case photos shown here are published with the patients' consent.
View other case studies here
Japanese Anti-AgingBoard-certified specialist
Ministry of Health, Labour and Welfare – Accredited Facility for Regenerative Medicine Provision Plan
Ministry of Health, Labour and Welfare
Accredited Facility for Regenerative Medicine Provision Plans
Type 2 and Type 3 Regenerative Medicine Provision Plans | Certification Number: NA8230001
In accordance with the "Act on Ensuring the Safety of Regenerative Medicine, etc.," our clinic
has filed a Regenerative Medicine Provision Plan with the Ministry of Health, Labour and Welfare and provides PRP therapy after receiving certification.
In accordance with the "Act on Ensuring the Safety of Regenerative Medicine, etc.," our clinic has filed a Regenerative Medicine Provision Plan with the Ministry of Health, Labour and Welfare and provides PRP therapy after receiving certification.

skin

Hair
*This shows part of the document.
Smart Essential
High-quality medical care at a price within reach.
We cut away excessive interiors and sales costs, and channel that into the quality of our formulations and our physicians' skill.
That is our clinic's "Smart Essential" philosophy.
High-quality medical care,
at a price within reach.
Cutting away excessive interiors and sales costs,
and channeling it into the quality of our formulations and our physicians' skill.
That is our clinic's "Smart Essential"
way of thinking.


First,FreeStarting with a consultation
Our clinic offers free consultations with no obligation to receive treatment.
We carefully listen to your concerns and wishes, and recommend the treatment that best suits you.
Reception Hours: Weekdays 11:00–20:00 / Weekends 10:00–19:00
About Risks and Side Effects of the Treatment
About the Risks of the Treatment—
and Its Side Effects
| Treatment name | Personalized PRP Injection *Depending on the patient's condition, a growth factor (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient's own blood, combined with a growth factor as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reaction, and greater-than-expected tissue growth (excessive swelling). Side effects vary from person to person, and the above does not cover all possible risks. Your treating physician will explain the details before the procedure. |
| Downtime | Swelling and redness from the day of the procedure to a few days (varies by area) |
| Growth factors (bFGF) | The bFGF (generic name: trafermin) that may be used in this procedure is the active ingredient of "Fiblast Spray" (approval number: 21300AMZ00387000), a domestically approved drug for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved drugs with the same active ingredient: none (it is an approved drug, but this is off-label use). |
| Approved drug | None (it is an approved drug, but this is off-label use) |
| Adverse drug reaction relief system | In the unlikely event of a serious side effect, it would not be covered by the national Adverse Drug Reaction Relief System. |
| Regenerative Medicine, etc. Provision Plan | This treatment is performed under the "Act on Ensuring the Safety of Regenerative Medicine, etc.," after filing a provision plan with the Ministry of Health, Labour and Welfare and receiving certification. Certification Number: NA8230001 (Type 2 and Type 3 Regenerative Medicine Provision Plans) |
| Treatment name | Personalized PRP Injection *Depending on the patient's condition, a growth factor (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient's own blood, combined with a growth factor as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reaction, and greater-than-expected tissue growth (excessive swelling). Side effects vary from person to person, and the above does not cover all possible risks. Your treating physician will explain the details before the procedure. |
| Downtime | Swelling and redness from the day of the procedure to a few days (varies by area) |
| Growth factor (bFGF) | The bFGF (generic name: trafermin) that may be used in this procedure is the active ingredient of "Fiblast Spray" (approval number: 21300AMZ00387000), a domestically approved drug for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved drugs with the same active ingredient: none (it is an approved drug, but this is off-label use). |
| Approved drug | None (it is an approved drug, but this is off-label use) |
| Adverse Drug Reaction Relief System | In the unlikely event of a serious side effect, it would not be covered by the national Adverse Drug Reaction Relief System. |
| Regenerative Medicine Provision Plan | This treatment is performed under the "Act on Ensuring the Safety of Regenerative Medicine, etc.," after filing a provision plan with the Ministry of Health, Labour and Welfare and receiving certification. Certification Number: NA8230001 (Type 2 and Type 3 Regenerative Medicine Provision Plans) |
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