PRP
Using your own blood,
NaturalAnti-aging care.
We are not aiming for flashy changes.
Something that I’ll still like about myself a year from now, and five years from now
We provide “natural, seamless anti-aging care.”
Duration
5more than [number] years
Down time
almost never
Number of treatments
1One-shot
*Basic

Using your own blood,
NaturalAnti-aging care.
Our goal is to,
It's not a dramatic change.
Something that I’ll still like about myself a year from now, and five years from now
We provide “natural, seamless anti-aging care.”
Duration
5more than [number] years
Down time
almost never
Number of treatments
1One-shot
*Basic

Signs that appear as we age include:
Skin"Surface"It's not just that.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs are not limited to the surface of the skin, but also extend deep within the skin"Tissue Volume Loss"...is involved.
Rather than unnaturally filling in the lost foundation, it promotes tissue regeneration from within using the power of your own cells.
That is Smart Skin Clinic’s approach.
Signs that appear as we age include:
Skin"Surface"just
It's not a problem.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs are not limited to the surface of the skin, but also extend deep within the skin"Tissue Volume Loss"...is involved.
Rather than unnaturally filling in the lost foundation, it promotes tissue regeneration from within using the power of your own cells.
That is Smart Skin Clinic’s approach.
What is personalized PRP injection?
Personalized PRP injections are a form of regenerative medicine in which platelets are purified from your own blood to a high concentration and then injected into the affected area.
Growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than “physically filling in wrinkles” like hyaluronic acid does,Your own cells regenerate tissueAs a result, the finish looks extremely natural.
STEP 01
drawing blood

Collect a small amount of blood
STEP 02
Refining

Purify PRP to a high concentration and
Formulated with FGF as needed
STEP 03
injection

To the Optimal Layer
Precise injection of the appropriate amount
At Smart Skin Clinic, we may incorporate growth factors (FGF) into our treatments depending on the patient's condition.
Based on past clinical data, we carefully determine the injection volume, depth, and location to minimize risks such as excessive swelling or lumps.
Personalized PRP Injection
Personalized PRP injections are a form of regenerative medicine in which platelets are purified from your own blood to a high concentration and then injected into the affected area.
Growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than “physically filling in wrinkles” like hyaluronic acid does,Your own cells regenerate tissueAs a result, the finish looks extremely natural.

STEP 01
drawing blood
Collect a small amount of blood

STEP 02
Refining
Purify PRP to a high concentration and
Formulated with FGF as needed

STEP 03
injection
To the Optimal Layer
Precise injection of the appropriate amount
At Smart Skin Clinic, we may incorporate growth factors (FGF) into our treatments depending on the patient's condition.
Based on past clinical data, we carefully determine the injection volume, depth, and location to minimize risks such as excessive swelling or lumps.
Our Philosophy
Naturally, beautifully.
Smart Skin Clinic: A "Center for Anti-Aging Care"
As an “Aging Care Hub”
Smart Skin Clinic
We continue to pursue “a more natural and beautiful rejuvenation,”
We hope to be your “hub for anti-aging care.”
That is precisely why we do not seek unnatural changes even with PRP treatments.
Our goal is that, whether it’s one year from now or five years from now,
"So you can love your own face,"Natural beauty that feels completely effortless".
We strive to be your “go-to destination for anti-aging care,” as we continue to pursue “a more natural and beautiful rejuvenation.”
That is precisely why we do not seek unnatural changes even with PRP treatments.
Our goal is to help you continue to love your face—whether it’s one year from now or five years from now—“Natural beauty that feels completely effortless".



As a center for anti-aging care, we offer Prophilo treatments, various devices, and exosomes, among other services.
Precisely because we offer a wide range of options, we do not make recommendations based solely on PRP from the outset.
First, we’ll listen carefully to your concerns and recommend only the treatments that are truly right for you.
What you need, in the amount you need—that’sThe Philosophy of Smart Skin ClinicIt is.
As a center specializing in anti-aging care, we offer a wide range of options—including Profhilo, various devices, and exosomes—which is precisely why we do not automatically recommend PRP as the first course of treatment.
First, we’ll listen carefully to your concerns and recommend only the treatments that are truly right for you.
What you need, in the amount you need—that’sThe Philosophy of Smart Skin ClinicIt is.
Our Protocol
Finding the Best Solution Just for You
4 Ways to Personalize
The key to PRP therapy is not to rely too heavily on the doctor’s personal judgment.
At our clinic, we have established clinically validated protocols and standards for every step of the process to ensure consistent and natural results.
The key to PRP therapy is not to rely too heavily on the physician’s personal judgment. At our clinic, we have established clinical guidelines and standards for every step of the process to ensure consistent and natural results.

- Personalized Diagnosis
Based on our clinic’s case data, we’ll analyze your bone structure and skin condition. We’ll determine whether PRP is the best option for you after comparing it with other alternatives.
- Personalization of Refining
Our clinic’s proprietary purification protocol, developed by synthesizing a wealth of clinical data.


- Design Customization
After analyzing the structure of the face, the doctor determines “where and in what quantity the filler should be injected to achieve the most natural lift.” The doctor then creates a treatment plan before proceeding with the procedure.
- Personalizing Injections
Our group has performed more than 20,000 injection procedures annually. We deliver the right amount to the right layer with precision.

Case StudySmart Skin's PRP: The Proof Is in the Results
Case Studyas proven by,
Smart Skin PRP
Our clinic has accumulated a wealth of case studies and treatment results specifically for PRP therapy alone.
Based on this wealth of data, we tailor our treatments to each individual’s bone structure and skin condition
We offer “personalized treatment” through diagnosis, purification, design, and administration.
Our clinic has accumulated a wealth of case studies and treatment results specifically for PRP therapy alone.
Based on this extensive data, we offer “personalized treatment” that involves diagnosis, purification, design, and injection, all tailored to each individual’s bone structure and skin condition.
Number of PRP Treatment Cases
1,000more than [number] items
*Jimbocho Clinic (Period: June 2023 – March 14, 2026)
Yokohama Clinic (Period: July 2025 – March 14, 2026)
dark circles under the eyes
Three months have passed

laugh lines
Three months have passed

The Entire Face
Three months have passed

The Entire Face
Three months have passed

* The case photos shown here are published with the patients' consent.
Click here for other case studies
Japanese Anti-AgingBoard-Certified Physician
Ministry of Health, Labour and Welfare
Ministry of Health, Labour and Welfare
Facilities with accreditation for regenerative medicine provision plans
Type II and Type III Regenerative Medicine Provision Plan | Certification Number: NA8230001
In accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.,” our clinic,
We have submitted a Regenerative Medicine Provision Plan to the Ministry of Health, Labor and Welfare and received certification before administering PRP therapy.
In accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.,” our clinic has submitted a regenerative medicine provision plan to the Ministry of Health, Labor and Welfare and received certification before implementing PRP therapy.

skin

Hair
*This is a partial view of the document.
Smart Essential
High-quality medical care at an affordable price.
We cut back on excessive interior design and operating costs, reinvesting those savings in the quality of our formulations and the skills of our physicians.
That is the concept behind our clinic’s “Smart Essential” approach.
High-quality medical care,
At an affordable price.
By cutting back on excessive interior design and operating costs,
It all comes down to the quality of the medication and the doctor's skill.
That’s our clinic’s “Smart Essential”
That's the idea.


First of allfreeFrom the counseling session
Our clinic offers free consultations that are not contingent on receiving treatment.
We will carefully listen to your concerns and wishes, and recommend the treatment that best suits you.
Reception Hours: Weekdays 11:00 a.m.–8:00 p.m. / Saturdays and Sundays 10:00 a.m.–7:00 p.m.
Risks and Side Effects Associated with the Procedure
Risks Associated with the Procedure—
About Side Effects
| Name of treatment | Personalized PRP Injections *Depending on the patient's condition, growth factors (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient’s own blood, combined with growth factors as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reactions, and unexpected tissue proliferation (excessive swelling). Side effects vary from person to person, and the list above does not cover all possible risks. Your treating physician will provide a detailed explanation before the procedure. |
| Down time | Swelling and redness lasting from the day of the procedure to a few days (varies depending on the area) |
| growth factor (bFGF) | bFGF (generic name: Trafelmin), which may be included in this treatment, is the active ingredient in “Fiblast Spray” (Approval No.: 21300AMZ00387000), a drug approved in Japan for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved pharmaceuticals containing the same active ingredient: None (Although it is an approved pharmaceutical, its use in this context is off-label.) |
| Approved Pharmaceuticals | None (Although this is an approved drug, it is being used off-label.) |
| Adverse Drug Reactions Victim Relief Program | In the unlikely event that a serious side effect occurs, it will not be covered by the national drug adverse reaction relief program. |
| Regenerative Medicine, etc. Service Plan | This treatment is conducted in accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.”, following the submission of a treatment plan to the Ministry of Health, Labor and Welfare and receipt of certification. Certification Number: NA8230001 (Type II and Type III Regenerative Medicine Treatment Plan) |
| Name of treatment | Personalized PRP Injections *Depending on the patient's condition, growth factors (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient’s own blood, combined with growth factors as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reactions, and unexpected tissue proliferation (excessive swelling). Side effects vary from person to person, and the list above does not cover all possible risks. Your treating physician will provide a detailed explanation before the procedure. |
| Down time | Swelling and redness lasting from the day of the procedure to a few days (varies depending on the area) |
| Growth Factor (bFGF) | bFGF (generic name: Trafelmin), which may be included in this treatment, is the active ingredient in “Fiblast Spray” (Approval No.: 21300AMZ00387000), a drug approved in Japan for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved pharmaceuticals containing the same active ingredient: None (Although it is an approved pharmaceutical, its use in this context is off-label.) |
| Approved Pharmaceuticals | None (Although this is an approved drug, it is being used off-label.) |
| Pharmaceutical Adverse Reaction Relief System | In the unlikely event that a serious side effect occurs, it will not be covered by the national drug adverse reaction relief program. |
| Regenerative Medicine Service Plan | This treatment is conducted in accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.”, following the submission of a treatment plan to the Ministry of Health, Labor and Welfare and receipt of certification. Certification Number: NA8230001 (Type II and Type III Regenerative Medicine Treatment Plan) |
![Official] Smart Skin Clinic|Aesthetic Dermatology Group (Jimbocho, Yokohama)](https://smartskin-clinic.com/wp-content/uploads/2023/05/Smart-skin-clinic-ロゴ500-×-100-px.png)
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