PRP
Use your own blood for
natural anti-aging care.
What we aim for is not flashy change.
We provide
“natural, seamless anti-aging care” that will help you continue to love yourself one year and five years from now.
Duration
5years and more
Downtime
Almost none
Number of Treatments
1Completed in one session
*Standard

Use your own blood for
natural anti-aging care.
What we aim for is
not dramatic change.
We provide
“natural, seamless anti-aging care” that will help you continue to love yourself one year and five years from now.
Duration
5years and more
Downtime
Almost none
Number of Treatments
1Completed in one session
*Standard

The signs of aging are not just a problem limited to the "surface" of the
skin.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs are caused not only by changes on the skin’s surface but also by “loss of tissue volume” deep within the skin.
Rather than unnaturally filling in the lost foundation, we use the power of your own cells to promote tissue regeneration from within.
That is the Smart Skin Clinic approach.
The signs of aging are not just a problem limited to the "surface" of the
skin.
Dark circles under the eyes, nasolabial folds, forehead wrinkles, sagging around the mouth, and overall sagging.
These signs involve not only the surface of the skin but also, deep beneath it,"tissue volume loss."is involved.
Rather than unnaturally packing something into the lost foundation, it encourages tissue to regenerate from within using the power of your own cells.
That is Smart Skin Clinic's approach.
What Is Personalized PRP Injection?
Personalized PRP injections are a regenerative medicine treatment in which platelets are purified from your own blood to a high concentration and injected into the areas of concern.
The growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than "physically filling in wrinkles" like hyaluronic acid does, your own cells regenerate the tissue, resulting in an extremely natural-looking finish.
STEP 01
Blood Draw

A small amount of blood is drawn
STEP 02
Purification

High-concentration PRP is purified
and FGF is added as needed
STEP 03
Injection

To the optimal layer
The appropriate amount is injected with precision
At Smart Skin Clinic, we may incorporate growth factors (FGF) depending on the patient's condition.
Based on past clinical data, we carefully determine the injection volume, depth, and location to minimize risks such as excessive swelling or lumps.
Personalized PRP Injection
Personalized PRP injection is a regenerative medicine treatment in which platelets are purified to a high concentration from your own blood and injected into the area of concern.
The growth factors contained in platelets stimulate the production of collagen and elastin, rebuilding tissue from within the skin.
Rather than "physically filling in wrinkles" as hyaluronic acid does,your own cells regenerate the tissue,so the result looks extremely natural.

STEP 01
Blood Draw
A small amount of blood is drawn

STEP 02
Purification
High-concentration PRP is purified
and FGF is added as needed

STEP 03
Injection
To the optimal layer
The appropriate amount is injected with precision
At Smart Skin Clinic, a growth factor (FGF) may be added depending on the patient's condition.
Based on past clinical data, we carefully design the injection volume, depth, and placement to minimize risks such as excessive swelling or lumps.
Our Philosophy
Naturally, beautifully.
Smart Skin Clinic as a "hub for anti-aging care"
As a "hub for anti-aging care"
Smart Skin Clinic
We are committed to the pursuit of “more natural and beautiful rejuvenation,” and we aim to be your “aging care hub” at
.
That is precisely why we do not aim for unnatural changes, even with PRP treatments.
Our goal is to help you continue to love your own face—whether it’s one year or five years from now—by achieving "natural beauty that feels completely comfortable.”
We are committed to the pursuit of “more natural and beautiful rejuvenation,” and we aim to be your “aging care hub” at
.
That is precisely why we do not aim for unnatural changes, even with PRP treatments.
Our goal is to help you continue to love your own face—whether it’s one year or five years from now—by achieving "natural beauty that feels completely comfortable.”



As a center for anti-aging care, we offer a wide range of options—including Profhilo, various devices, and exosomes
—which is precisely why we do not automatically recommend PRP from the outset.
First, we’ll listen carefully to your concerns and recommend only the treatments that are truly right for you.
Just what you need, in the right amount—that’s Smart Skin Clinic’s philosophy.
As a center for anti-aging care, we offer a wide range of options—including Profhilo, various devices, and exosomes
—which is precisely why we do not automatically recommend PRP from the outset.
First, we’ll listen carefully to your concerns and recommend only the treatments that are truly right for you.
Just what you need, in the right amount—that’s Smart Skin Clinic’s philosophy.
Our Protocol
Find the Best Solution Just for You
4 Personalized
The key to PRP therapy is not to rely too heavily on the physician’s personal judgment.
At our clinic, we have established clinical guidelines and standards for every step of the process to ensure consistent, natural-looking results.
The key to PRP therapy is not to rely too heavily on the physician’s personal judgment.
At our clinic, we have established clinical guidelines and standards for every step of the process to ensure consistent, natural-looking results.

- Personalized Diagnosis
Based on our clinic's case data, we analyze your bone structure and skin condition. We determine whether PRP is the best option by comparing it against other alternatives.
- Personalized Purification
Our clinic's own purification protocol, derived by synthesizing a wealth of clinical results.


- Personalized Design
We calculate the structure of your face to determine "where and in what amount to place the material for the most natural lift of the tissue." The physician builds a blueprint before proceeding with the treatment.
- Personalized Injection
Our group has performed over 24,000 injection procedures annually. We deliver the right amount to the right layer with precision.

Smart Skin's PRP, as Demonstrated by Case Studies
Smart Skin's PRP, as Demonstrated by Case Studies
Our clinic has accumulated a wealth of case studies and treatment results specifically for PRP therapy alone.
Based on this extensive data, we offer “personalized treatment” that involves
diagnosis, purification, design, and injection tailored to each patient’s individual skeletal structure and skin condition.
Our clinic has accumulated a wealth of case studies and treatment results in PRP therapy alone.
Based on this extensive data, we provide "personalized treatment"—diagnosis, purification, design, and injection—tailored to each individual's bone structure and skin condition.
Number of PRP Treatment Cases
1,000and more
*Jimbocho Clinic (period: June 2023 – March 14, 2026)
Yokohama Clinic (period: July 2025 – March 14, 2026)
dark circles under the eyes
Three months later

Nasolabial folds
Three months later

The entire face
Three months later

The entire face
Three months later

*The case photos shown here are published with the patients' consent.
View other case studies here
Japanese Anti-AgingBoard-certified specialist
Ministry of Health, Labour and Welfare – Accredited Facility for Regenerative Medicine Provision Plan
Ministry of Health, Labour and Welfare
Accredited Facility for Regenerative Medicine Provision Plans
Type 2 and Type 3 Regenerative Medicine Provision Plans | Certification Number: NA8230001
In accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.,” our clinic has submitted a regenerative medicine provision plan to the Ministry of Health, Labor and Welfare (
) and received certification before implementing PRP therapy.
In accordance with the “Act on Ensuring the Safety of Regenerative Medicine, etc.,” our clinic has submitted a regenerative medicine provision plan to the Ministry of Health, Labor and Welfare (
) and received certification before implementing PRP therapy.

skin

Hair
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Smart Essential
High-quality medical care at a price within reach.
We eliminate excessive interior design and operating costs, reinvesting those savings in the quality of our treatments and the skills of our physicians.
That is the philosophy behind our “Smart Essential” approach.
High-quality medical care,
at a price within reach.
We eliminate excessive interior design and operating costs, reinvesting those savings in the quality of our treatments and the skills of our physicians.
That is the philosophy behind our “Smart Essential” approach.
Start with a free consultation
Our clinic offers free consultations with no obligation to undergo treatment.
We will listen carefully to your concerns and wishes and recommend the treatment that best suits your needs.
Reception Hours: Weekdays 11:00–20:00 / Weekends 10:00–19:00
About Risks and Side Effects of the Treatment
About the Risks of the Treatment—
and Its Side Effects
| Treatment name | Personalized PRP Injection *Depending on the patient's condition, a growth factor (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient's own blood, combined with a growth factor as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reactions, and unexpected tissue proliferation (excessive swelling). Side effects vary from person to person, and the list above does not cover all possible risks. Your treating physician will provide a detailed explanation before the procedure. |
| Downtime | Swelling and redness from the day of the procedure to a few days (varies by area) |
| Growth factors (bFGF) | The bFGF (generic name: trafermin) that may be used in this procedure is the active ingredient of "Fiblast Spray" (approval number: 21300AMZ00387000), a domestically approved drug for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved drugs with the same active ingredient: none (it is an approved drug, but this is off-label use). |
| Approved drug | None (it is an approved drug, but this is off-label use) |
| Pharmaceutical Adverse Reaction Compensation System | In the unlikely event of a serious side effect, it would not be covered by the national Adverse Drug Reaction Relief System. |
| Regenerative Medicine, etc. Service Plan | This treatment is performed under the "Act on Ensuring the Safety of Regenerative Medicine, etc.," after filing a provision plan with the Ministry of Health, Labour and Welfare and receiving certification. Certification Number: NA8230001 (Type 2 and Type 3 Regenerative Medicine Provision Plans) |
| Treatment name | Personalized PRP Injection *Depending on the patient's condition, a growth factor (bFGF) may be added. |
|---|---|
| Treatment Overview | This is a regenerative medicine treatment in which PRP is purified from the patient's own blood, combined with a growth factor as needed, and injected into the target area. |
| Risks and Side Effects | Swelling, pain, bruising, subcutaneous nodules (lumps), hyperpigmentation, allergic reactions, and unexpected tissue proliferation (excessive swelling). Side effects vary from person to person, and the list above does not cover all possible risks. Your treating physician will provide a detailed explanation before the procedure. |
| Downtime | Swelling and redness from the day of the procedure to a few days (varies by area) |
| Growth factor (bFGF) | The bFGF (generic name: trafermin) that may be used in this procedure is the active ingredient of "Fiblast Spray" (approval number: 21300AMZ00387000), a domestically approved drug for wound healing. Its use in PRP therapy constitutes off-label use. Other domestically approved drugs with the same active ingredient: none (it is an approved drug, but this is off-label use). |
| Approved drug | None (it is an approved drug, but this is off-label use) |
| Pharmaceutical Adverse Reaction Compensation System | In the unlikely event of a serious side effect, it would not be covered by the national Adverse Drug Reaction Relief System. |
| Regenerative Medicine, etc. Service Plan | This treatment is performed under the "Act on Ensuring the Safety of Regenerative Medicine, etc.," after filing a provision plan with the Ministry of Health, Labour and Welfare and receiving certification. Certification Number: NA8230001 (Type 2 and Type 3 Regenerative Medicine Provision Plans) |
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