A Doctor Explains! Why they say Rejuran is "ineffective" and how to experience its effects.

I've been asking myself, "Does Rejuran not work? Does it really work?"
When will I start feeling the effects of Rejuran?"
How long will Rejuran last?"

Are you at Rejran and have these questions?

Hello, I am a doctor at Smart Skin Clinic.

Some of you may be curious about Rejuran but have heard that it is not effective. We will explain the misconceptions about the effects and effectiveness of Rejuran from our professional standpoint as a cosmetic dermatology clinic.

This article will give you a better understanding of Rejuran, its effectiveness, and the measures you can take to experience its benefits.

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Rejuran is effective.

Conclusion,Rejuran is a proven effective treatmentIt is.

However, effectiveness can be achieved only when used appropriately, and the manifestation of effectiveness varies from person to person.

What is Rejuran?

First, what kind of effect can we expect from Rejuran?

Rejuran is one of the injectable treatments aimed at improving skin texture, and uses a formulation based on "polynucleotides" extracted from salmon.

Polynucleotides contain astaxanthin, an antioxidant 1,000 times more potent than vitamin E. It acts on the dermal layer deep within the skin to activate fibroblasts. Fibroblasts are cells that produce collagen and hyaluronic acid, which are the source of elasticity and moisture. They also produce new blood vessels and calm inflammation, and are expected to regenerate the skin.

[Riduran action].

  • Activates fibroblasts
  • Activation of angiogenesis
  • anti-inflammatory action

Effects of Rejuran

What can be felt early on is a change in the skin's surface luster and makeup application. Subsequently, the increase in collagen and elastin inside the skin will produce firmness and elasticity, which will improve fine lines and wrinkles, pores, sagging, and fine lines.

However, dramatic changes such as surgical procedures cannot be expected.

[Expected effects

  • Leads to firm, radiant, and flawless skin
  • Improves wrinkles, sagging, and lines by bringing moisture and elasticity
  • Pore tightening
  • Supports metabolism, skin regeneration and repair
  • Improve wrinkles around the eyes and dark circles under the eyes
  • Improve rough skin, acne, and scars

The effectiveness of Rejuran for skin rejuvenation, including improvement of pores and skin thickness, dullness, blotches, wrinkles, and sagging skin, is described in the following research paper on "Injection of polynucleotide-containing products (≒ Rejuran) for cheek rejuvenation in more than 5 Korean patients".

Five Korean women received four injections of long-chain PN filler at 2-week intervals for skin rejuvenation. Approximately 0.05 mL of material was injected at 40 sites on one cheek; patients in their 30s showed marked improvement in pores and skin thickness, whereas those in their 40s showed marked improvement in skin tone, melanin, wrinkles, and sagging.

Kui Young Park, Joon Seok, Nark Kyoung Rho, Beom Joon Kim, Myeung Nam Kim. long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Dermatologic therapy. 2016 Jan-Feb;29(1);37-40. doi: 10.1111/dth.12299.

Types and Characteristics of Rejuran

There are four different formulations of Rejuran for different purposes.
Some clinics combine Rejelan with other preparations and treat it as an original procedure.

 Rejuran (Healer)Rejuran iRejuran sRejuran HB
ComponentPolynucleotides 20mg/ccPolynucleotides 20mg/cc polynucleotidePolynucleotides 10mg/cc
+hyaluronic acid (HA) 10mg
+Lidocaine 2.8mg/cc
hardnessduring (a certain time when one did or is doing something)lowamount of moneyduring (a certain time when one did or is doing something)
EffectPowerful skin texture improvementImprovement of wrinkles and dark circles around the eye area (exclusively for the eye area)Acne scar improvement, craters, indentations (pinpoint use)Close to healer
PainIntense pain during injectionAbout the usual drug level except for Rejuran HealerAbout the usual drug level except for Rejuran HealerLidocaine (local anesthesia) is added to reduce pain

Rejuran i is a formulation for use exclusively around the eyes, while Rejuran s is a pinpoint formulation for acne scars. Rejuran HB contains lidocaine, which has been reported to reduce pain by 561 TP3T compared to Rejuran Healer.

Reasons why people say Rejuran is not effective

Although Rejuran has these various effects, it is sometimes said to be "ineffective.

It is not a case of ineffectiveness of Rejuran, but rather a case of misunderstanding due to the way the effect was manifested or not being effective due to non-adaptation.

Not immediately effective.

Rejuran does not have an immediate effect. It takes time for fibroblasts to be activated by the injection and for new cells to be born and grow.

In addition, the effect of a single treatment is small, and the effect increases with repeated treatments; quitting after one treatment may result in a "less effective" result than expected.

Effects are not permanent.

The skin texture improvement effect of Rejuran can be expected for more than one year, but the effect is not permanent.

In addition, since the polynucleotides stimulate fibroblasts and activate the skin's natural functions, the way the effect is manifested depends on lifestyle and skin care.

It's not an adaptation.

The effects of any treatment cannot be realized unless it is indicated.

For example, young, healthy skin will have difficulty perceiving changes. Also, fine lines and wrinkles are indicated, but for deeper wrinkles, a physically volumizing preparation such as hyaluronic acid, rather than Rejelan, is more appropriate.

In addition, there are four different formulations of Rejuran. They differ in ingredient ratio and hardness, and each has its own suitable area and treatment. By selecting the formulation that best suits your purpose, you can expect the maximum effect.

Measures to realize the effects of Rejuran

To avoid the "ineffective" results of the Rejuran treatment, we will tell you the points you need to know and the measures you need to take.

Receive the appropriate number and frequency of treatments.

Rejuran should be treated regularly.

The recommended frequency of treatment is "3 to 4 times every 3 weeks, and then once every 6 months to a year as maintenance.

Select the right formulation for the site

Rejuran injections are indicated for a wide range of areas, including not only the face but also the neck and the backs of the hands.

Selecting a suitable formulation, such as Rejuran i for dark circles under the eyes, Rejuran (Healer) for laugh lines, or Rejuran HB for those who are sensitive to pain, will lead to natural-looking results and comfortable treatments.

Be aware of postoperative behavior.

Bathing and makeup can be done after surgery, but avoid strenuous exercise, prolonged bathing, saunas, and other activities that heat the body. Downtime symptoms may be more severe.

In addition, skin that has been pricked with needles is more prone to dryness and damage than usual because the barrier function has been weakened. Thorough moisturizing and UV protection are recommended.

Receive treatment at a reputable medical institution.

Rejuran should be received at a reputable medical institution.

First, narrow down the list of potential clinics by checking their websites and social networking sites for formulations, case photos, and costs. The results of injectable treatments vary depending on the skill of the physician.

Since fees vary from clinic to clinic, it is advisable to compare the total amount and choose a clinic that offers clear accounting.

Finally, a pre-counseling session is used to discuss the situation to your satisfaction and decide where to receive treatment.

Kiara Reju, a polynucleotide formulation similar to Rejuran

Chiara Rege Product Images

Rejuran is a formulation whose main ingredient is a polynucleotide (PDRN).

This polynucleotide is sometimes called "salmon injection" because it is derived from salmon.

Rejuran was patented as a formulation using this "polynucleotide," but this patent has recently expired, and several inexpensive formulations using polynucleotides are now available.

One of these will be "Kiara Reju" injections.Riguran GenericThe product will be an injection formulation that stands like a

Like Rejuran, it is a polynucleotide-based formulation and is less expensive than Rejuran.

At Smart Skin Clinic, the following prices are available for Chiara Rejuvenation injections with water light injections.

1 bottle (2.2cc)
Once24,800 yen → 22,320 yen
3 sets68,400 yen → 58,140 yen
(per time)19,380 yen)
4 sets79,200 yen → 63,360 yen
(per time)15,840 yen)
2 bottles (4.4 cc)
Once34,800 yen → 31,320 yen
3 sets92,400 yen → 78,540 yen
(per time)26,180 yen)
4 sets115,200 yen → 92,160 yen
(per time)23,040 yen)
3 bottles (6.6cc)
Initial Price36,800 yen
Once39,800 yen → 35,820 yen
3 sets104,400 yen →. 88,740 yen
(per time)29,580 yen)
4 sets131,200 yen →. 104,960 yen
(per time)26,240 yen)

If you are interested in Chiara Lege, please also see the following articles

If you want to receive Rejuran, go to Smart Skin Clinic.

Have your questions about the effectiveness of Rejuran been answered?

Rejuran is a treatment that is easy to feel the effects of if used appropriately. Select the formulation that best suits the area and your needs, understand when and how long the effects will appear, and undergo regular treatment at a reliable medical institution.

Smart Skin Clinic's Rejelan will choose the right formulation for each individual client, and will also provide advice on how the results will appear after the treatment and how to spend downtime. The price is clear and reasonable.

If you are interested in Smart Skin Clinic's Rejuran, please also see below.


In addition, our clinic has the following "particulars" in injections of Rejuran and other products.

Reference

Kui Young Park, Joon Seok, Nark Kyoung Rho, Beom Joon Kim, Myeung Nam Kim. long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Dermatologic therapy. 2016 Jan-Feb;29(1);37-40. doi: 10.1111/dth.12299.

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