SUNECOS injection|Smart Skin Clinic (Jimbocho, Tokyo)

*Number of cases|From September 1, 2023 to March 31, 2024

I wonder, "What kind of injections are snecos injections, and how do they work?"
I'm trying to choose a clinic to get snekos injections."

Do you have any of these questions or concerns?

In this article, Smart Skin Clinic, a cosmetic dermatology clinic, will provide easy-to-understand explanations from a professional standpoint to help you resolve these questions and concerns.

*If you want to know the rates, you can also jump from the table of contents below.


What is SUNEKOSinjection?

SUNECOS Product Images

SUNECOS injections are a procedure in which a preparation (drug) called "SUNECOS" is injected into the face.

The Snecos formulation is,"Non-cross-linked hyaluronic acid."andSix amino acids."The main ingredient of the product is a formulation of

What is non-cross-linked hyaluronic acid?

There are two types of hyaluronic acid: "cross-linked" and "non-cross-linked." The cross-linked type is the conventional hyaluronic acid that everyone has a quick image of. Specifically, hyaluronic acid is a solid substance that is filled deep into the skin to increase the skin's firmness and elasticity.

On the other hand, non-cross-linked hyaluronic acid injects soft hyaluronic acid rather than solid material, which penetrates to naturally replenish skin firmness and elasticity and increase its volume.

Six amino acids

The names of the six amino acids in the SNECOS formulation and their actions are listed below. These amino acids act on the dermis deep within the skin to naturally increase collagen and elastin.

Glycine| Collagen production
Natural moisturizing factor (NMF), hyaluronic acid production, fibroblast stimulation
Collagen production
L-alanine| Elastin and collagen production
Elastin generation, maintenance of skin elasticity and firmness
(6) L-Leucine| Provides instructions to tissues to promote protein synthesis

One of the unique features of the SNECOS formulation is that the ratio of this "non-cross-linked hyaluronic acid" and "amino acids" is an internationally patented special formula.

This ratio has proven to be an efficient ratio in enhancing ingredients such as collagen and elastin deep in the skin (dermis).

We will tell you about the specific benefits you can obtain in the "Effects" section.

In addition, the "CE Mark Class IIIReceived approval for conformity with European safety standardsIn other words, it is a safe and reliable product approved by an agency like the Ministry of Health, Labor and Welfare in Japan. To put it simply, it is a highly safe drug approved by an agency similar to the Ministry of Health, Labour and Welfare in Japan. The reason why we are in Europe is because SNECOS is made in Italy.

There are two types of SNECOS formulations|SUNECOS 200 and SNECOS 1200

There are actually two types of Snecos formulations, Snecos 200 and Snecos 1200. The well-known one is the "200" formulation.

Perhaps the snecos originally envisioned by the reader of this article will be the "200".

The difference between the two is the "molecular weight" of the non-cross-linked hyaluronic acid. Specifically, SUNECOS 200 is "low molecular weight" and SUNECOS 1200 is "medium molecular weight".

The difference in molecular weights is too technical and will be omitted.

Importantly, thisDifferent molecular weights are good at different parts of the molecule."That is to say.

Please see the table below.



ComponentLow molecular weightNon-cross-linked hyaluronic acid + 6 amino acidsMiddle moleculeNon-cross-linked hyaluronic acid + 6 amino acids
EffectImprovement of firmness and luster, fine lines and wrinkles, dark circlesImprovement of deep wrinkles, wrinkles on the laugh lines
Areas of expertiseAround the eyes, under the eyesLines, marionette lines, cheek moss

As you can see from the table here, "1200" may give you the impression that it is a formulation that solves problems at a deeper level of the skin. This perception is true, because the larger the molecular weight, the stronger the "volumizing" action.

Smart Skin Clinic has not introduced SUNECOS 1200.

The reason for this is that there is a formulation called Profibro, which is as good at treating lines and deep wrinkles as SUNECOS 1200. The areas in which SUNECOS 1200 is strong are almost the same as those of Profibro, so those who prefer SUNECOS 1200 should also consider Profibro as an option.

For more information on PROFHILO, click here.

The Snecos.Recommended for the following problems

If you have read this far, you probably have these questions and concerns.

In what cases should I choose a Sneco formulation?"
I'm not sure I'm really in the right Snecos formulation."

Our cosmetic dermatologists will solve your problem in a professional and easy-to-understand manner.

Let me first tell you the conclusion.

If any of the following apply to you, SUNECOS is a good option.

[The main target audience for the SUNECOS formulation].
Those who suffer from dark circles under their eyes.
Those who suffer from fine lines and wrinkles around the eyes
Those who suffer from dryness around the eyes.

Your hopes and concerns
Hyaluronic acid injections and surgical procedures "don't feel natural," so I prefer procedures that allow for natural changes.
I have been told that dark circles and fine lines under my eyes cannot be cured, but I want to do something about it.
I don't want a procedure that causes more than 3 days of downtime.

To explain in detail, Snechos is aStrong around the eyes."It is good to recognize that it is a formulation.

In fact, until the SUNECOS formulation was introduced, problems around the eyes (dark circles, fine lines) were one of the most difficult problems to solve.

It is against this background that the SUNECOS formulation has come out, and we hope that those who suffer from dark circles and fine lines under the eyes will consider it.

If you suffer from wrinkles that do not improve easily or deep wrinkles,Jubeluk Volume (Renisna)"Another option is PDLLA, an injectable formulation that is strong in volume enhancement.

In the following article.Jubeluk Volume (Renisna)"The following is a detailed explanation of the


We hope that you have understood the effects of the SUNECOS formulation in the "Recommended for such problems" section above, but we will explain it again.

The following effects can be summarized in an organized manner.

[Main effects] (Effects most expected by customers)
Improvement of dark circles under the eyes
Improvement of fine lines around the eyes

[Other effects
Improvement of dryness around eyes
Improvement of skin elasticity and firmness around the eyes
Reduction of sagging under the eyes

We would like to introduce one medical paper that provides evidence for the above effects. The following clinical studies have demonstrated the "effects on problems around the eyes".

HA-AA application (≈snecos injection) isThey concluded that it is effective in healing dark circles and wrinkles in women aged 30-55.Participant feedback also revealed an increase in eyebrow height and an increase in upper eyelid height. Therefore,HA-AA application (≈snekos injection) can be used for periorbital (i.e., around the eyes) rejuvenation.

Ayse Gul Kabakci, et al. Assessing the Rejuvenation Effectiveness of a Hyaluronic Acid and Amino Acid Mixture in the Periorbital Region. Investig Dermatol. 2023; 16: 973-980.

Why is the SUNECOS formulation so effective?

We hope you understand the effectiveness of SUNECOS.

Next, I will explain the mechanism and mechanism of "Why is the SUNECOS formulation effective?" The following is an explanation of the mechanism of why the Snecos formulation is so effective.

Many of you may not "need to know" how this works, so please skip this section unless you are interested.

To understand how SUNECOS works, it is important to understand what causes each of these problems in the first place.

Therefore, we will explain why "dark circles under the eyes" and "fine lines under the eyes" occur, respectively.

Why do dark circles under the eyes occur?

First, "dark circles under the eyes" are classified into three types depending on the cause as follows.

(1) Blue dark circles
Dark circles that show through the blood vessels and muscles (orbicularis oculi) under the skin. It is said to be caused by volume loss under the skin and poor circulation.

(2) Black bear (shadow bear)
Dark circles shadowed by "fat" under the eyes. The main cause is sagging skin due to aging.

(3) Brown bear
Dark circles that have become colored due to pigmentation. Melanin pigmentation.

Of these, the best indication for SUNECOS will be (1) blue dark circles. The reason is that blue dark circles are caused by volume loss due to a decrease in collagen and elastin in the skin under the eyes.

Snecos has the ability to compensate for this volume loss, which is expected to improve blue dark circles.

Why do fine lines around the eyes occur? Why do they tend to dry out?

Fine lines and wrinkles form due to the following factors

  • age| The most common cause, which occurs naturally as we age.
  • ultra-violet rays| Sunburn is known to destroy collagen and elastin and accelerate skin aging.
  • smoking|Smoking worsens blood flow and decreases the supply of oxygen and nutrients needed by the skin.
  • facial expression| Frequent changes in facial expression stress certain skin areas and cause fine lines to form.
  • dryness|Dry skin makes wrinkles more noticeable and accelerates their formation.

The above factors cause the following reactions in the skin

  • Decreased collagen and elastin| These proteins are important components of skin elasticity and strength. As we age, production of these proteins declines and the skin tends to sag.
  • Decreased water retention capacity| The skin's ability to retain moisture decreases due to a decrease in hyaluronic acid and other moisture-retaining components of the skin. This leads to dry skin and the development of fine wrinkles.
  • Decreased ability of cells to regenerate|The rate of skin cell regeneration slows with age. This makes it easier for damage to accumulate and wrinkles to form.

The above reactions occur inside the skin and result in the appearance of "fine lines and wrinkles.

As you may understand from reading this far, the Snekos formulation is effective in the direction of "improving" the above reactions.

One of the factors contributing to the formation of fine lines and wrinkles is "dryness," especiallyAreas around the eyes are prone to drynesswill be.

Why is the area around the eyes prone to dryness? It is for two main reasons

  • Due to the thin thickness of the skin under the eyes|About half of the thickness of the cheeks
  • Because there are few sebaceous glands that secrete sebum

For two reasons: thin skin and few sebaceous glands, the area around the eyesA delicate area with low water retention capacity, prone to dryness."This is the case.

The SUNECOS formulation also moisturizes the under-eye area with non-cross-linked hyaluronic acid and six amino acids, which means that it is not only a current treatment, but also a preventive effect.

Snecos formulations areNaturally increases collagen and elastin

When injected into the area of the skin called the dermis, non-cross-linked hyaluronic acid and six amino acids, which are components of SNECOS, stimulate cells called fibroblasts. When stimulated, fibroblasts are activated and produce the components collagen and elastin.

This collagen and elastin are the components that produce skin firmness and elasticity. By increasing these components, it is possible to restore and produce skin firmness and elasticity naturally.

Case photos (before/after)

Snekos case photo (1)
Snekos case photo (2)
Snekos case photo (3)

Name of Treatment|Snekos Injection

Treatment Description|Treatment to improve dark circles and fine lines under the eyes by intradermal administration of a drug that has the effect of activating collagen and elastin in the dermis.

Redness, swelling, and internal bleeding at the injection site

Price of treatment|1 time (3 cc): 27,500 yen to 33,000 yen (including tax)

Treatment area/method

For the SUNECOS, a fine needle is used to inject 10 to 30 areas per side in fine detail.

The area and extent of injections will be customized according to the individual's concerns, but the following is a basic idea of what is involved.

SUNECOS injection point

Recommended number/frequency of treatments|How many times should I have the treatment?

This item is a question that is often asked during actual counseling, so we will explain it in the form that we actually tell you at the clinic.

How many times is it best to take SUNECOS?"

Set of 4I think it would be a good idea to take it in

How long is the best interval between visits?"

About 2 weeks intervalis a good idea.

The reason why we do not use an assertive tone is that the effects of cosmetic dermatology procedures vary from person to person, and we are providing information neutrally based on the methods recommended by cosmetic dermatologists in general and the methods recommended by manufacturers. Although we do not make any assurances, we basically recommend that you receive the above-mentioned number of treatments and frequency.

Spacing between other treatments

Since many people have received other cosmetic procedures beforehand or wish to receive cosmetic procedures in the future, we often receive these questions during the counseling process.

We will explain the information so that your questions will be answered by reading this page.

I'm having another laser, how long should I leave it open?"

If the laser is not applied under the eyes (in the area of the snecos injection), there is no problem with spacing.

When applying/applying under the eyes, we recommend an interval of at least 2 weeks, preferably 1 month.

Not only laser, but any other treatment can basically be considered as above.

Can I have other treatments on the same day?"


Since SUNECOS injections are for one area, under the eyes, it is possible to perform other procedures on the same day.

For example, a profilo injection can be performed on the same day.

Are there any disadvantages of the SUNECOS formulation?

Basically, the "Risks, Side Effects, and Downtime" described in this article should be sufficient.

For more detailed information, please also see the following articles.

Pain intensity|Need for anesthesia

The degree of pain in the snecos is low to moderate.

Necessity of AnesthesiaLow to medium

Smart Skin Clinic's SUNEKOS InjectionFeatures of

Those who are not eligible for the treatment

Basically, it is possible to perform the procedure unless you have some serious illness or inflammation in the area to be treated.

The following information is provided for reference only, as we are obliged to include it to inform "those who are not eligible for the treatment".

  • Pregnant or nursing mothers
  • Persons with abnormal immune function or with a history of such abnormality, and persons receiving immunosuppressive therapy.
  • Those prone to keloid formation, hypertrophic scars and hyperpigmentation
  • Those with bleeding tendency or using non-steroidal anti-inflammatory analgesics such as aspirin or anticoagulants such as warfarin
  • Excessive sunburn, eczema, dermatitis, highly inflamed acne, or scabs at the snecos injection site

Risks and Side EffectsDowntime

Risks, side effects, and downtime may mean almost the same thing to you, so we will explain them all together.

In SUNECOS injections, the SUNECOS preparation is injected under the eye with a needle in several dozen or more places on each side. Therefore, the following reactions may occur

Redness, swelling (puffiness), and pain occur at the site of injection.

Above Response,In most cases, it will return to normal within 24 hours.

Another point I will always tell you,Internal bleeding."This is about the possibility of the occurrence of This one may be incorrectly perceived, so we will explain it carefully.

First, please see below.

Due to the nature of the treatment, internal bleeding may occur at the needle puncture site, although not always. If internal bleeding does occur, it will gradually disappear over a period of one to two weeks.

As described here, internal bleeding occurs with a certain frequency (about 3~101 TP3T).

Internal bleeding is when a needle strikes a "blood vessel" (called a vein) under the skin and causes a slight break in the vessel, causing it to bleed and clot.

In other words, in order to prevent this from happening, it is "better if it does not hit a blood vessel." However, these blood vessels (veins) are very thin and run differently (where they are located) from person to person. Therefore, it is not possible to prevent 100% by the skill of the doctor alone.

At Smart Skin Clinic, we "stick" to ultra-fine needles and make every effort to reduce the risk of internal bleeding as much as possible. We hope you will understand this when you come to our clinic.

The downtime process is explained in more detail in the following article. For more detailed information, please also see the following article.

Aftercare|Advice for daily life after treatment

We will first summarize the "what not to do" items and then explain in detail why.

Let's start with the following list of "what not to do" after the procedure.

[What not to do in the next 24 hours
Strenuous exercise
Bathing in hot temperatures
Excessive alcohol consumption
Use of retinol and hydroquinone cream

[What to avoid in the next 24 hours].
Injection siteMakeup *Can be applied except under the eyes.

[What you may do in the next 24 hours.
Wash your face gently to avoid friction.
Use non-irritating cosmetics and moisturizers.

[To be avoided within a week.
Massage around the area to be treated
Use of retinol and hydroquinone cream

Next, we will briefly explain the reasons why you should not do it.

The area injected with SUNECOS has a mildInflammation."The company is now in the process of

Inflammation is simply put.It's a state in which the body is doing its best to get back to normal."We can say. They are doing their best to improve the injection site, so it is best to leave them alone.

Common among "what not to do within 24 hours" are "excessive blood flow and heat." These can promote inflammation, which can result in a condition called "inflammatory hyperpigmentation" and slow healing.

In short,To avoid contributing to inflammation, do not irritate the area and allow it to heal naturally."That is to say.


Snekos Rates

1 time (1 bottle|3cc)33,000 yen
Set of 2 (2 bottles)62,000 yen
(31,000 yen per session)
Set of 4 (4 pcs.)110,000 yen
(per time)27,500 yen)
All prices include tax.
We are a free clinic and not covered by insurance.

Price includes consultation fee and ultrafine needle (see image below) fee
There will be no separate upsell on the day of the event.

Need for anesthesia|Low

This procedure is basically considered anesthesia-free.
We would like to maintain this price, so if you would like cream anesthesia5,500 yen (tax included) / 1 time(*This is because anesthesia will increase the time by about 20 minutes. (*This is because anesthesia will increase the time by about 20 minutes.)

Sneco Spaforma Rates

Compared to traditional snecos, "snecospaforma" is now more effective thanks to the following three enhancements
①Amino acid content|100mg to 128mg, a 28% increase
(2) Non-cross-linked hyaluronic acid: increased from 30 mg to 35 mg
Hyaluronic acid degradation reaction|40% reduction

1 time (1 bottle|3.5cc)43,800 yen
2 sets83,600 yen
(41,800 yen per session)
4 sets159,200 yen
(1 time)39,800 yen)

Need for anesthesia|Low

This procedure is basically considered anesthesia-free.
We would like to maintain this price, so if you would like cream anesthesia5,500 yen (tax included) / 1 time(*This is because anesthesia will increase the time by about 20 minutes. (*This is because anesthesia will increase the time by about 20 minutes.)

Flow of treatment


You can easily make reservations with your mobile phone.

Reception (desk)

This is a "smart" and easy receptionist service that can be completed immediately by the clinic's IT system by simply providing your name.

Counseling and consultation by a physician

Please feel free to discuss any concerns you may have during the counseling session. Please be assured that there is no pushy sales.

SUNEKOS injection

We will carefully carry out the injection while talking to the patient.

After-sales service

We will explain in detail about the care of the treated area and precautions for daily life.

Returning home


What is the difference between SUNECOS injections and conventional hyaluronic acid?

Hyaluronic acid is injected subcutaneously, and in order to make it less likely to be absorbed, hyaluronic acid is bonded to other hyaluronic acid. This process is called "cross-linking," and is performed to maintain skin elasticity and hydration for a long period of time. However, if this "cross-linked hyaluronic acid" accidentally enters a blood vessel, there is a risk of clogging within the artery, resulting in vascular occlusion.

On the other hand, non-cross-linked hyaluronic acid is hyaluronic acid that has not been processed to be "cross-linked. Unlike regular hyaluronic acid, the hyaluronic acid used in SUNEKOS injections is not cross-linked. This is expected to reduce the risk to the body and the risk of post-injection results.

Which should I choose, SUNEKOS 200 or 1200?

The clinic only offers SUNECOS 200.
For the eye area, I would use 200; 1200 would be applicable for "deeper" wrinkles such as lines, hands, etc. In such cases, Profibro injections would be a good indication, so please consider Profibro.

How effective is one session?

Although there are individual differences, even one session can be expected to improve dark circles and fine lines. Basically, a set of 3 to 4 times is required for this treatment to be effective.

How long do the effects last?

It will vary from 9 months to 1 year, depending on the individual. It also varies with lifestyle, skin care, and other factors.

Can I wear makeup on the same day?

Since the procedure is performed on the eye area, it can be done on the same day except for the eye area. For the areas to be treated, the next day is recommended.

More Information

Treatment TimeAbout 15 minutes (not including counseling)
Recommended number and frequency of treatmentsAround the eyes|3-4 times every 2 weeks
[Reference] Whole face|About 4 times every 7 to 10 days
Down timeAbout 24 hours
Treatment on the day of counselingPossible
MakeFrom the next day
Skin careFrom the next day
ShowerPossible from the same day
PainThere is a stinging pain when the needle is inserted.
*There are individual differences.

[Legal description

SUNEKOS injections include procedures using drugs or medical devices that are not approved in Japan. The medicines and devices used in the treatment have been imported on a personal import basis under the judgment of our physicians.

Please refer to this page for information on medicines, etc. that should be noted for personal importation.
Ministry of Health, Labour and Welfare, "Medicines, etc. that Require Caution in Personal Importation".

Smart Skin Clinic

Smart Skin Clinic

The concept of the clinic is to "make cosmetic medicine more accessible and smart. is the concept of the clinic.

Instead of eliminating ornate interiors to reduce interior design costs and installing equipment in the dark, we carefully select the equipment we need and reduce the cost of the equipment.

We aim to "make cosmetic medicine more accessible" for you.

Address:EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)

Address: EX Kanda Nishiki-cho Building 8F, 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo
Specialty: Cosmetic dermatology (cosmetic dermatology, medical hair removal, medical slimming)

About the physician supervision of this site

About the physician supervision of this site

This site is operated under the supervision of the Smart Skin Clinic supervising physicians.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.

This page is produced under the supervision of our supervising physician, who also operates the website as a medical institution in accordance with the Medical Advertising Guidelines, which were revised and enforced in June 2018.