PLURYAL SILK [Injection formulation exclusively for the eye area
*Number of cases｜From September 1, 2023 to March 31, 2024
What is pull-real silk?"
I'm looking for a clinic where I can get pull-real silk at a reasonable price."
I need to do something about the wrinkles and dark circles around my eyes."
I wonder if there is an effective treatment for the eye area."
Hello, I am a doctor at Smart Skin Clinic, a cosmetic dermatology clinic.
I am sure you all have these questions.
In this article,Pull Real Silk, one of four in the Pull Real Densifiers series.The cosmetic dermatology clinic will provide a professional and easy-to-understand explanation of the following.
*If you want to know the rates, you can quickly see them in the table of contents below.
What is Plurial Silk?
PullReal Silk is a formulation developed specifically for the eye area.CE approved for use exclusively around the eyesThe product is an injectable formulation that is rapidly gaining popularity, especially in Europe.
The three features are as follows
- CE approved for use around the eyes only： Safety and efficacy for the delicate area around the eyes have been recognized.
- High purity polynucleotide (PN) formulation： Special purification technology simultaneously maximizes efficacy and minimizes allergy risk.
- Formulation design suitable for delicate areas： Specially designed to have the right viscosity and penetration for thin and delicate skin areas such as around the eyes and mouth.
Positioning in the Plurial Series
Plurial Silk is the only one in the Plurial series,Products specialized for the eye areaIt is.
Other products include Plurial Densify for the whole face and Plurial Hair Density for hair growth, but Plurial Silk occupies an important position in the series as a formulation optimized for a specific area, the eye area.
Main ingredient: polynucleotides (PN)
The main ingredient of Plurial Silk is polynucleotide (PN), a highly purified PN derived from salmon. This PN has a variety of benefits.
- Increased skin hydration： PN has high water retention properties and improves the skin's ability to retain moisture.
- antioxidant action： PN is a powerful antioxidant and prevents skin damage caused by free radicals. This can be expected to slow down the skin aging process.
- anti-inflammatory action： PN has anti-inflammatory properties and inhibits skin inflammation.
- Promotes fibroblast proliferation： PN promotes fibroblast proliferation. Fibroblasts are important cells that produce collagen and elastin, and their proliferation leads to improved skin elasticity.
- DNA repair and regeneration： PN promotes DNA repair and regeneration. This helps skin cells recover from damage caused by UV rays and other factors.
- Promotion of angiogenesis： PN stimulates the secretion of vascular endothelial growth factor (VEGF) and promotes angiogenesis. This improves skin blood flow and nutrient supply.
Applicable areas for plurial silk
PLURYAL SILK can be applied mainly to the following areas
- around one's eyes
- around one's lips
- Other sensitive areas (e.g., scars)
Effective for the following problems
Pull Real Silk is especially effective for those with the following concerns
- Those who are concerned about wrinkles and sagging around the eyes
- Those who are concerned about dark circles under the eyes
- Fine wrinkles around the eyes and mouth
- Those with skin problems due to chronic inflammation (e.g., hyperpigmentation of atopic dermatitis, redness of acne scars)
- Those who feel a decrease in skin elasticity and firmness
Until PullReal Silk came out, problems around the eyes (dark circles, fine lines) were one of the most difficult problems to solve. It is against this background that Plurial Silk was developed.
Expected Benefits
The use of pull-real silk can be expected to
- Improvement of wrinkles and sagging： The cellular regenerative effect of PN promotes collagen and elastin production, which improves wrinkles and sagging.
- Improvement of skin qualityPN's moisturizing and cellular regeneration effects improve skin texture and overall skin quality.
- Improvement of dark circles： Due to its angiogenesis-promoting and anti-inflammatory effects, it is expected to improve dark circles and dark circles under the eyes.
- Reduction of redness： Anti-inflammatory action reduces chronic redness and inflammation.
- Improvement of skin elasticity and firmness： Increased collagen and elastin improves skin firmness and elasticity.
- Long-term skin rejuvenation effect： With continuous use, the skin's regeneration cycle is activated and a long-term rejuvenation effect can be expected.
*These effects depend on individual differences and skin conditions.
PLURYAL SILK is unique in that it gradually enhances the skin's natural functions rather than having an immediate effect. Therefore, natural rejuvenation is possible and can be expected to improve skin texture without giving the impression that any treatment has been performed.
Mechanism of action of Plurial Silk
Plurial silk is effective through the following mechanisms
- tissue regeneration： PN activates fibroblasts and promotes collagen and elastin production.
- angiogenesis： Promotes the secretion of VEGF and the formation of microvessels. This improves the skin's nutritional status.
- anti-inflammatory action： Inhibits the production of inflammatory cytokines and reduces chronic inflammation.
- scar repair： Promotes the reconstruction of the extracellular matrix and contributes to the improvement of scars.
Smart Skin Clinic Pull RealCharacteristics of the "Kao Group's" commitment to injectable formulations
Our director's policy is to implement the following "particulars" in injections.
Charge
| 1 time (1 bottle 2cc) | 44,800 yen |
| 3 sets | 119,400 yen (per time)39,800 yen) |
| 4 sets | 155,200 yen (per time)38,800 yen) |
Treatment Method
The procedure for pull-real silk is as follows:
- Counseling： We will listen to the patient's concerns and wishes, and diagnose the skin condition in detail. We will then propose the optimal treatment plan.
- Preparation before treatment： I would clean and disinfect the treatment area. I apply a local anesthetic cream if necessary.
- injection： Using a special fine needle or cannula, a small amount is injected into the necessary areas, such as around the eyes and mouth.
- Explanation of post-treatment care： We will explain in detail the precautions and appropriate skin care procedures and confirm the next treatment schedule.
The procedure usually takes about 20 to 30 minutes. We recommend that you expect to stay at the clinic for approximately one hour, including counseling and preparation time before and after the procedure.
Recommended number/frequency of treatments
The standard treatment plan for Plurial Silk is as follows
- Initial treatment: 3~4 treatments at 2-3 week intervals
- Maintenance: 1 treatment every 6 to 12 months depending on effectiveness
However, this is only a guide, as cosmetic dermatology procedures vary from person to person in terms of the effects they produce.
Side Effects and Risks
Plurial silk is aAllergy risk is extremely low.It is. Common side effects include the following
- Redness, swelling (puffiness), and pain at the site of injection
- internal hemorrhage
Most of these reactions return to normal within 24 hours.However, if internal bleeding occurs, it will gradually disappear over a week or two.
The clinic makes every effort to minimize the risk of internal bleeding by using ultrafine needles.
After-sales service
After the procedure, please note the following
- Avoid strenuous exercise and alcohol consumption on the day of treatment
- Avoid hot environments such as rock baths and saunas for about a week.
- Do not touch the treatment area unnecessarily
- Perform skin care as directed by a physician.
By following these precautions, safer and more effective results can be achieved.
Frequently Asked Questions (FAQ)
Q1: When can I start seeing results?
A: Although the effects of the treatment vary from person to person, the general process is as follows:
- Immediately after the treatment: Some patients may feel a mild sensation of tightness.
- After 1 week: Many people start to notice a mild improvement in their skin, as it begins to look firmer and shinier.
- After 2-4 weeks: Collagen production is activated and the full effect begins to appear.
- After 2-3 months: This is when the greatest effect is seen.
PullReal Silk has the characteristic of gradually improving the skin, rather than having an immediate effect.
Q2: How old do I have to be to take the course?
A: There is no specific age limit, but generally people in their late thirties to sixties are most likely to receive this service. Those who wish to receive care at an earlier age and younger people can also receive this service. However, those under 18 years of age must have parental consent.
Q3: Is there any pain?
A: Due to the use of an extremely fine needle, pain is relatively mild. Many patients describe it as only mild irritation or pressure. If desired, a local anesthetic cream can be used.
Q4: How long do the effects last?
A: Although there are individual differences, the effect usually lasts from 6 months to 1 year. Regular maintenance (about once every 3 to 6 months) will help maintain the effect for a longer period of time.
Q5: Can I receive the treatment while pregnant or nursing?
A: For safety reasons, we do not recommend this procedure for pregnant or nursing mothers. We recommend that the procedure be performed after pregnancy and lactation are over.
Q6: Can it be combined with other cosmetic treatments?
A: Yes, it can be used in conjunction with many cosmetic treatments. In particular, it is considered to be compatible with Botox and laser treatments. However, when used in combination, it is necessary to keep an appropriate interval between treatments, so I would recommend that you consult with your doctor beforehand.
Q7: What should I take care of after the surgery?
A: After the procedure, please note the following
- Avoid strenuous exercise and alcohol consumption on the day of treatment
- Avoid hot environments such as rock baths and saunas for about a week
- Do not touch the treatment area unnecessarily!
- Please follow your doctor's instructions for skin care
Q8: How much does it cost?
A: Costs vary from clinic to clinic. The market price in Tokyo is approximately 50,000-100,000 yen/treatment. (as of June 2025).
Plurial Silk vs. other eye area treatments
Compare PullReal Silk to other common eye area treatments.
Comparison with Botox
Botox
- Main effects: Improvement of expression lines and wrinkles, reduction of wrinkles at the corners of the eyes
- Mode of action: Inhibits muscle movement
- Duration: 3-6 months
- Characteristics: Immediate effect, but natural look may be compromised
pull-real silk
- Main effects: wrinkle improvement, skin texture improvement, dark circles improvement
- Mode of action: Promotes cell regeneration and collagen production
- Duration: 6 months to 1 year
- Characteristics: Long-term improvement of skin texture while maintaining a natural look
Unlike Botox, PLURYAL SILK does not inhibit muscle movement, so it provides a rejuvenating effect while maintaining a more natural look. You can also expect a fundamental improvement in skin texture.
Comparison with hyaluronic acid injection
hyaluronic acid injection
- Main effects: volume replenishment, immediate wrinkle improvement
- Mode of action: physically lifts skin
- Duration: 6 months to 1 year
- Characteristics: Immediate effect, but may cause unnatural volume
pull-real silk
- Main effects: wrinkle improvement, skin texture improvement, creation of natural elasticity
- Mode of action: Promotes cell regeneration and collagen production
- Duration: 6 months to 1 year
- Characteristics: Gradual effect and natural rejuvenation
PLURYAL SILK does not provide immediate volume like hyaluronic acid injections, but rather enhances the skin's natural functions to achieve a natural rejuvenation effect. It also improves dark circles and other effects that are difficult to achieve with hyaluronic acid injections.
Comparison with laser therapy
laser therapy
- Main effects: Skin tightening, pigmentation improvement
- Mechanism of action: Acceleration of skin regeneration by thermal energy
- Duration: Varies with effect, usually 6 months to 1 year
- Characteristics: There is downtime, and multiple treatments are often required
pull-real silk
- Main effects: wrinkle improvement, skin texture improvement, dark circles improvement
- Mode of action: Promotes cell regeneration and collagen production
- Duration: 6 months to 1 year
- Characteristics: Almost no downtime, and makeup can be applied on the same day.
PLURYAL SILK has almost no downtime compared to laser treatments and is less burdensome for patients. It can also improve dark circles and other effects that are difficult to achieve with laser treatments.
summary
Plurial silk is chosen by many for the following reasons
- Overall Improvement Effectiveness： It can simultaneously address various problems around the eyes, such as wrinkles, sagging, dark circles, and skin texture.
- Natural finish： Enhances the skin's natural functions, resulting in a rejuvenating effect that is not unnatural.
- Long-term effects： Not only temporary improvement, but also gradual improvement in skin condition with continuous use.
- Hypoallergenic and low risk： The use of highly purified PN means that the risk of allergies is extremely low, making it suitable for people with sensitive skin.
- Less downtime： You can go back to your daily life immediately after the procedure, and makeup can be applied on the same day.
- Possibility of concomitant use with other treatments： Even higher effects can be expected when used in combination with other treatments such as Botox or laser therapy.
Because of these features, PullReal Silk is getting a lot of attention as the new standard for eye area treatment. However, depending on the individual case and desired effect, other treatments or a combination of treatments may be appropriate. Please consult with our physicians regarding the best treatment option.
We hope that Plurial Silk can be your first step toward regaining a beautiful, confident look. For more information or an individual consultation, we invite you to schedule a consultation.
Clinic List
Jimbocho Institute
〒101-0054
EX Kanda Nishiki-cho Building 8F (general reception), 3-16-1 Kanda Nishiki-cho, Chiyoda-ku, Tokyo 7F
Business hours: Monday-Friday 11:00-20:00 / Saturday and Sunday 10:00-19:00
Yokohama Institute of Technology
〒221-0835
TS Plaza Bldg. 2F, 2-23-2 Tsuruya-cho, Kanagawa-ku, Yokohama-shi, Kanagawa
Business hours: 10:00-19:00